SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Björklund Stefan) ;srt2:(2020-2024)"

Sökning: WFRF:(Björklund Stefan) > (2020-2024)

  • Resultat 1-42 av 42
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Abdel-Fattah, Wael R., et al. (författare)
  • Growth-regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes
  • 2024
  • Ingår i: Nucleic Acids Research. - : Oxford University Press. - 0305-1048 .- 1362-4962. ; 52:11, s. 6220-6233
  • Tidskriftsartikel (refereegranskat)abstract
    • Mediator is a well-known transcriptional co-regulator and serves as an adaptor between gene-specific regulatory proteins and RNA polymerase II. Studies on the chromatin-bound form of Mediator revealed interactions with additional protein complexes involved in various transcription-related processes, such as the Lsm2–8 complex that is part of the spliceosomal U6 small nuclear ribonucleoprotein complex. Here, we employ Chromatin Immunoprecipitation sequencing (ChIP-seq) of chromatin associated with the Lsm3 protein and the Med1 or Med15 Mediator subunits. We identify 86 genes co-occupied by both Lsm3 and Mediator, of which 73 were intron-containing ribosomal protein genes. In logarithmically growing cells, Mediator primarily binds to their promoter regions but also shows a second, less pronounced occupancy at their 3́-exons. During the late exponential phase, we observe a near-complete transition of Mediator from these promoters to a position in their 3́-ends, overlapping the Lsm3 binding sites ∼250 bp downstream of their last intron–exon boundaries. Using an unbiased RNA sequencing approach, we show that transition of Mediator from promoters to the last exon of these genes correlates to reduction of both their messenger RNA levels and splicing ratios, indicating that the Mediator and Lsm complexes cooperate to control growth-regulated expression of intron-containing ribosomal protein genes at the levels of transcription and splicing.
  •  
2.
  • Adli, Erik, et al. (författare)
  • Progress Of The Ess Proton Beam Imaging Systems
  • 2022
  • Ingår i: LINAC2022. - : ACoW Publishing. ; , s. 395-398
  • Konferensbidrag (refereegranskat)abstract
    • The ESS Target Proton Beam Imaging Systems has the objective to image the 5 MW ESS proton beam as it entersthe spallation target. The imaging systems has to operate in a harsh radiation environment, leading to a number of challenges : development of radiation hard photon sources, long and aperture-restricted optical paths and fast electronics required to provide rapid information in case of beam anomalies. This paper outlines how main challenges of the imaging systems have been addressed, and the status of deployment as ESS gets closer to beam.
  •  
3.
  • Baiamonte, Lidia, et al. (författare)
  • Carbide-laden coatings deposited using a hand-held high-velocity air-fuel (HVAF) spray gun
  • 2021
  • Ingår i: Surface & Coatings Technology. - : Elsevier BV. - 0257-8972 .- 1879-3347. ; 406
  • Tidskriftsartikel (refereegranskat)abstract
    • Driven by sustainability and cost considerations, there is growing interest in power generation utilizing renewable sources, especially biomass and waste. While premature degradation of power plant components due to corrosion is well-known, erosion can be a dominant damage mechanism in plants that use “pure” biomass with less corrosive elements like Cl, K, etc. Circulating fluidized bed (CFB) parts are prone to erosion-driven damage and demand periodic re-protection or replacement. In response to the above, this preliminary study evaluates a selection of complex carbide-based coatings to enhance protection against erosion to prolong service life of boiler components. Recognizing on-site coating requirements of real boiler applications, a specific focus is on evaluating performance of a hand-held high-velocity air-fuel (HVAF) spray gun and compare it with the current state-of-the-art high-velocity oxy-fuel (HVOF) deposition. Coatings developed by the above routes have been characterized with microstructural analyses, and their performance evaluated and ranked in an air-jet erosion rig at various impact angles.
  •  
4.
  • Bellippady, Madhura, et al. (författare)
  • Characteristics and performance of suspension plasma sprayed thermal barrier coatings on additively manufactured superalloy substrates
  • 2023
  • Ingår i: Surface and Coatings Technology. - : Elsevier. - 0257-8972. ; 472
  • Tidskriftsartikel (refereegranskat)abstract
    • The complex-shaped hot-section parts of new-generation turbine engines demand unique design solutions. Additive Manufacturing (AM) is an emergent production method that can produce metallic parts with complex geometries and minimal material wastage. In this work, the characteristics and performance behavior of Thermal Barrier Coatings (TBCs) deposited on forged and AM-built HAYNES®282® superalloy substrates were studied and compared. The bond coats were produced by High-Velocity Air-Fuel (HVAF) spraying using NiCoCrAlY powder feedstock and TBC top-coats by Suspension Plasma Spraying (SPS) using water- and ethanol-based suspensions of Yttria-Stabilized Zirconia (YSZ). The microstructural features, adhesion, Thermal Cycling Fatigue (TCF) lifetime, and thermal shock lifetimes of the TBCs were comprehensively investigated. The results showed that the deposition of bond coats reduced the roughness and asperities of the AM-built substrates. Depending on the type of suspension used and the spray parameters employed, the TBCs exhibited vertically cracked and columnar microstructures. However, no significant differences in TCF and thermal shock lifetimes of TBCs on AM and forged substrates were observed. It is demonstrated that TBC systems can be produced on AM-built metallic substrates, and the resulting TBCs can have similar microstructures and properties as TBCs deposited on conventional substrates.
  •  
5.
  • Bellippady, Madhura, et al. (författare)
  • Performance of Atmospheric Plasma-Sprayed Thermal Barrier Coatings on Additively Manufactured Super Alloy Substrates
  • 2024
  • Ingår i: Coatings. - : MDPI. - 2079-6412. ; 14:5
  • Tidskriftsartikel (refereegranskat)abstract
    • This work represents a preliminary study of atmospheric plasma-sprayed (APS) YttriaStabilized Zirconia (YSZ)-based thermal barrier coatings (TBCs) deposited on forged and additivemanufactured (AM) HAYNES®282® (H282) superalloy substrates. The effect of different feedstockmorphologies and spray gun designs with radial and axial injection on APS-deposited YSZ layercharacteristics such as microstructure, porosity content, roughness, etc., has been investigated. Theperformance of TBCs in terms of thermal cycling fatigue (TCF) lifetime and erosion behaviour werealso comprehensively investigated. In view of the high surface roughness of as-built AM surfacescompared to forged substrates, two different types of NiCoCrAlY bond coats were examined: oneinvolved high-velocity air fuel (HVAF) spraying of a finer powder, and the other involved APSdeposition of a coarser feedstock. Despite the process and feedstock differences, the above two routesyielded comparable bond coat surface roughness on both types of substrates. Variation in porositylevel in the APS topcoat was observed when deposited using different YSZ feedstock powdersemploying axial or radial injection. However, the resultant TBCs on AM-derived substrates wereobserved to possess similar microstructures and functional properties as TBCs deposited on reference(forged) substrates for any given YSZ deposition process and feedstock. 
  •  
6.
  • Bellippady, Madhura, et al. (författare)
  • Process Parameter Impact on Axial Plasma Sprayed Ytterbium Disilicate Coatings for Environment Barrier Coating Applications
  • 2024
  • Ingår i: Sustainable Production through Advanced Manufacturing, Intelligent Automation and Work Integrated Learning. - : IOS Press. - 9781643685106 - 9781643685113 ; , s. 101-110
  • Bokkapitel (refereegranskat)abstract
    • In future generation aviation, light weight, and thermally stable SiC/SiC ceramic matrix composites (CMCs) are considered the most promising structural materials to replace traditionally used Ni-based superalloys. However, in the presence of steam (a common combustion reaction product) and corrosive species (from ingestion of debris along with the intake air during take-off and landing), accelerated degradation of CMCs compromising its structural integrity is inevitable. Environmental Barrier Coatings (EBCs) are protective ceramic coatings consisting of rare earth (RE) silicates as a topcoat with silicon as a bond coat, and are widely used on CMCs, to impede their surface recession.Thermal spray techniques are commonly employed to deposit EBCs, with highly crystalline, dense, and crack free coatings being desired for robust performance. In general, the high particle velocity and efficient energy transfer in axial feeding systems can result in coatings with higher density, reduced oxide content, and improved mechanical properties. In the present study, axial plasma sprayed ytterbium disilicate (YbDS) coatings deposited on silicon carbide (SiC) substrates using varying plasma spray parameters have been comprehensively characterized. Microstructure, porosity, and hardness have been studied for YbDS coatings deposited by varying nozzle diameter, carrier gas flow rate and stand of distance (SOD) during plasma spraying. Erosion and thermal cyclic fatigue performance of these coatings has also been investigated. 
  •  
7.
  • Björklund, Ann-Christin, et al. (författare)
  • Using ICF to Describe Problems With Functioning in Everyday Life for Children Who Completed Treatment for Brain Tumor : An Analysis Based on Professionals' Documentation
  • 2021
  • Ingår i: Frontiers in Rehabilitation Sciences. - : Frontiers Media S.A.. - 2673-6861. ; 2
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Children treated for brain tumors often experience persistent problems affecting their activity performance and participation in everyday life, especially in school. Linking these problems to the International Classification of Functioning, Disability and Health (ICF) classification system can be described as affecting body function, activity performance, and/or participation. Services involved in the everyday life of the child have different focus and goals when meeting the child in context, which advantage the use of ICF to overcome this impediment to follow-up and provide comprehensive support for children who have completed treatment for a brain tumor.Aim: The aim of the study was to use the ICF classification system to describe how professionals in healthcare, habilitation, and school document problems with everyday life functioning at body, activity, and participation levels for children who completed treatment for a brain tumor.Materials and Methods: A retrospective review of records from healthcare, habilitation, and school concerning nine children completed treatment for brain tumor was implemented. Identified problems in everyday life were linked to ICF codes. Descriptive statistics of ICF-linked code frequency supplemented by network visualization diagrams viewing the co-occurrence between codes within the body, activity participation, and environmental components were performed.Results: Most documented problems were found in healthcare records, whereas the documentation in habilitation and school was sparse. The frequently occurring codes, independent of record source, were linked to the body function component, and ICF-linked problems in habilitation and school were salient in the activity and participation component. To gain a holistic picture of relations between ICF codes and problems, network visualization diagrams were used to illustrate clusters of problems.Conclusion: Code prevalence likely reflects where healthcare professionals and educators focus their attention when meeting the needs of children treated for a brain tumor in context. To maximize the comprehensive view of functioning and participation of children in everyday life, the full range of difficulties regarding body impairments, activity limitations, and participation restrictions must be identified and linked to each other in patterns of co-occurrence, which the ICF facilitate. However, ICF provides no guidance on how to identify networks of problems within the body, activity, and participation. Identifying such networks is important for building comprehensive interventions for children.
  •  
8.
  • Blomberg, Jeanette, et al. (författare)
  • Pseudomonas syringae infectivity correlates to altered transcript and metabolite levels of Arabidopsis mediator mutants
  • 2024
  • Ingår i: Scientific Reports. - : Springer Nature. - 2045-2322. ; 14:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Rapid metabolic responses to pathogens are essential for plant survival and depend on numerous transcription factors. Mediator is the major transcriptional co-regulator for integration and transmission of signals from transcriptional regulators to RNA polymerase II. Using four Arabidopsis Mediator mutants, med16, med18, med25 and cdk8, we studied how differences in regulation of their transcript and metabolite levels correlate to their responses to Pseudomonas syringae infection. We found that med16 and cdk8 were susceptible, while med25 showed increased resistance. Glucosinolate, phytoalexin and carbohydrate levels were reduced already before infection in med16 and cdk8, but increased in med25, which also displayed increased benzenoids levels. Early after infection, wild type plants showed reduced glucosinolate and nucleoside levels, but increases in amino acids, benzenoids, oxylipins and the phytoalexin camalexin. The Mediator mutants showed altered levels of these metabolites and in regulation of genes encoding key enzymes for their metabolism. At later stage, mutants displayed defective levels of specific amino acids, carbohydrates, lipids and jasmonates which correlated to their infection response phenotypes. Our results reveal that MED16, MED25 and CDK8 are required for a proper, coordinated transcriptional response of genes which encode enzymes involved in important metabolic pathways for Arabidopsis responses to Pseudomonas syringae infections.
  •  
9.
  • Crawford, Tim, et al. (författare)
  • Specific functions for Mediator complex subunits from different modules in the transcriptional response of Arabidopsis thaliana to abiotic stress
  • 2020
  • Ingår i: Scientific Reports. - : Nature Publishing Group. - 2045-2322. ; 10:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Adverse environmental conditions are detrimental to plant growth and development. Acclimation to abiotic stress conditions involves activation of signaling pathways which often results in changes in gene expression via networks of transcription factors (TFs). Mediator is a highly conserved co-regulator complex and an essential component of the transcriptional machinery in eukaryotes. Some Mediator subunits have been implicated in stress-responsive signaling pathways; however, much remains unknown regarding the role of plant Mediator in abiotic stress responses. Here, we use RNA-seq to analyze the transcriptional response of Arabidopsis thaliana to heat, cold and salt stress conditions. We identify a set of common abiotic stress regulons and describe the sequential and combinatorial nature of TFs involved in their transcriptional regulation. Furthermore, we identify stress-specific roles for the Mediator subunits MED9, MED16, MED18 and CDK8, and putative TFs connecting them to different stress signaling pathways. Our data also indicate different modes of action for subunits or modules of Mediator at the same gene loci, including a co-repressor function for MED16 prior to stress. These results illuminate a poorly understood but important player in the transcriptional response of plants to abiotic stress and identify target genes and mechanisms as a prelude to further biochemical characterization.
  •  
10.
  • Fefekos, Alexandros G., et al. (författare)
  • Effect of spray angle and substrate material on formation mechanisms and properties of HVAF sprayed coatings
  • 2023
  • Ingår i: Surface & Coatings Technology. - : Elsevier. - 0257-8972 .- 1879-3347. ; 452
  • Tidskriftsartikel (refereegranskat)abstract
    • Thermally sprayed coatings are often used to enhance the surface properties (wear resistance, corrosion resistance, etc.) of engineering components in order to extend their performance and service lifetime. Typically, the industrial components to be coated possess complex geometries and are fabricated using different materials, which can influence the deposited coating’s microstructure and performance. High-velocity air fuel (HVAF) process is a relatively new thermal spray processing technique that has shown tremendous potential to deposit high performance coatings for durable industrial components. However, no detailed studies have been reported on HVAF sprayed coating formation mechanisms so far in relation to the spray angle and substrate properties, and the influence of coating material on the above. The objective of this work was to study the influence of spray angles and substrate materials on splat characteristics, coating microstructure evolution, properties and performance for two distinct coating materials. In this study, one cermet (WC-CoCr) and one metallic (Inconel 625) feedstock were deposited onto three different substrates (aluminium alloy, carbon steel and Hastelloy-X) utilising different spray angles (40°, 60° and 90°). The coating evolution was analysed utilising SEM/EDS, image analysis, and micro-indentation. To determine the tribological performance, coatings were subjected to dry sliding wear test utilising alumina ball as counter surface and specific wear rates were obtained. The results showed that initial splat characteristics were substantially altered on changing the substrate and the spray angle. However, the final coating properties were not affected significantly even though the deposition rate was reduced significantly at lower spray angle, suggesting the versatility of the HVAF process. 
  •  
11.
  • Frost, Robert J. W., et al. (författare)
  • Preliminary results from a study of luminescent materials : For application in the beam imaging system at the ESS
  • 2023
  • Ingår i: Nuclear Instruments and Methods in Physics Research Section B. - : Elsevier. - 0168-583X .- 1872-9584. ; 540, s. 227-233
  • Tidskriftsartikel (refereegranskat)abstract
    • As part of the development of the beam imaging system at the European Spallation Source, luminescent screens have been fabricated by the flame spraying of scintillating materials onto stainless steel backings. A total of seven screens were produced, three of chromia alumina (Al2O3:Cr), two of YAG (Y3Al5O12:Ce) and two of a 50/50 mix of these. The properties of these screens under proton irradiation were evaluated using a2.55 MeV proton beam at currents of up to 10 μA. Irradiation times were up to 25 h per sample, during which luminescence-, spectrographic-, thermal- and current-data was sampled at a rate of 1 Hz. Preliminary results of these measurements are reported here; with a quantitative analysis presented for one of the chromia alumina screens and a qualitative comparison of all three material types. The luminescent yield for chromia alumina was determined to be around 2000 photons/MeV for a virgin screen, and was found to drop to 1.5% after 167 mC of proton irradiation. A recovery of the luminescence of chromia alumina to >60% was observed after beam current was reduced for an 8 h period. Observations indicate that the YAG and mixed composition screens retain higher luminescence than the chromia alumina even at temperatures of over 200 ◦C. It is indicated that the luminescence from YAG feeds the R-lines of chromia alumina in the mixed composition screens. 
  •  
12.
  • Ganvir, Ashish, 1991-, et al. (författare)
  • Novel utilization of liquid feedstock in high velocity air fuel (HVAF) spraying to deposit solid lubricant reinforced wear resistant coatings
  • 2021
  • Ingår i: Journal of Materials Processing Technology. - : Elsevier BV. - 0924-0136 .- 1873-4774. ; 295
  • Tidskriftsartikel (refereegranskat)abstract
    • The ability to axially inject liquid feedstock has encouraged the thermal spray research community to explore this concept to deposit coatings for various next generation functional applications. The current study explores the utilization of liquid feedstock in high velocity air fuel (HVAF) spraying to deposit solid lubricant reinforced wear resistant coatings for the first time. The study successfully demonstrates the use of a powder-suspension hybrid processing approach to incorporate a solid lubricant Boron Nitride (as suspension) in a wear resistant Cr3C2–NiCr (as powder) cermet matrix. Coatings were characterized using Scanning Electron Microscopy and Raman Spectroscopy to analyze their microstructure and phase constitution. The results show that the tribological performance of the hexagonal boron nitride (hBN)-incorporated composite coating was significantly better than the traditional powder-derived Cr3C2–NiCr coating. Such hBN-incorporated composite coatings are needed to improve the mechanical properties and enhance the overall tribological performance of metallic components used in various applications, especially at high temperature such as cylinder bore, pistons, deformation tools, etc. The limitations of liquid based lubricants at high temperature motivates the use of hBN reinforced composite coatings as it can form a protective solid lubrication tribo-film. The study concludes that the emerging HVAF technology can accommodate liquid feedstock and be successfully utilized to deposit hybrid powder-suspension composite coatings to create multi length scale microstructures which can be attractive for combining different tribological attributes in the same coatings system.
  •  
13.
  • Ganvir, Ashish, 1991-, et al. (författare)
  • Tribological performance assessment of Al2O3-YSZ composite coatings deposited by hybrid powder-suspension plasma spraying
  • 2021
  • Ingår i: Surface and Coatings Technology. - : Elsevier BV. - 0257-8972 .- 1879-3347. ; 409
  • Tidskriftsartikel (refereegranskat)abstract
    • The advent of high-throughput plasma spray systems that allow axial feeding encourages the study of using liquid feedstock for various next-generation functional applications. The current study explores the benefit of such a plasma spray system to deposit hybrid powder-suspension Al2O3-YSZ ceramic matrix composite (CMC) coatings for tribological applications. The tribological performance of the hybrid processed CMC coatings was assessed using scratch, ball-on-plate wear and erosion tests and compared with that of monolithic powder-derived Al2O3 coatings. As-deposited and tribo-tested coatings were characterized using Scanning Electron Microscopy, X-ray Diffraction and Energy Dispersive Spectroscopy to analyse their microstructure and phase constitution. The results showed that the tribological performance of the hybrid powder-suspension Al2O3-YSZ CMC coating was significantly improved by enhancing the wear resistance under scratch, dry sliding ball-on-plate and erosion tests as compared to the conventional APS deposited monolithic Al2O3 coating. About 36% decrease in the dry sliding ball-on-plate specific wear rate and up to 50% decrease in the erosion wear rate was noted in the hybrid powder-suspension Al2O3-YSZ CMC coating as compared to the conventional APS deposited monolithic Al2O3 coating. The study concludes that the hybrid powder-suspension route can create CMC coatings with unique multi-length scale microstructures which can be attractive for combining different tribological attributes in the same coating system.
  •  
14.
  • Goel, Sneha, 1993-, et al. (författare)
  • Axial Plasma Spraying of Mixed Suspensions : A Case Study on Processing, Characteristics, and Tribological Behavior of Al2O3-YSZ Coatings
  • 2020
  • Ingår i: Applied Sciences. - : MDPI. - 2076-3417. ; 10:15
  • Tidskriftsartikel (refereegranskat)abstract
    • Thermal spraying deploying liquid feedstock offers an exciting opportunity to obtain coatings with characteristics vastly different from those produced using conventional spray-grade powders. The most extensively investigated variant of this technique is Suspension Plasma Spraying (SPS), which utilizes a suspension of fine powders in an appropriate medium. The relatively recent advent of axial feed capable plasma spray systems can enable higher throughputs during SPS, provides the possibility for spraying with longer stand-off distances, and also permit the use of suspensions with higher solid loading. The present work investigates axial plasma sprayed coatings produced using a mixed suspension of fine (submicron or nano-sized) powders of Al(2)O(3)and YSZ as a case study. Deposition of the mixed suspension using axial injection plasma spraying, comprehensive evaluation of characteristics of the resulting coatings, and assessment of their tribological behavior were of particular interest. Evaluation of surface morphology, microstructure, and hardness of the coatings reveals that axial SPS of mixed suspensions provides an exciting pathway to realize finely structured multi-constituent coatings using suspensions with as high as 40 wt.% solid loading. The study of scratch, dry sliding wear, and erosion behavior also specifically shows that the addition of YSZ in the Al(2)O(3)matrix can improve the tribological properties of the coating.
  •  
15.
  • Henriksson, Robin, 1986- (författare)
  • Secondary prevention after acute coronary syndrome : antiplatelet therapy and risk factor control
  • 2020
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Background: One of the leading causes of death and disability worldwide is cardiovascular disease (CVD), including acute myocardial infarction (AMI). Despite improvements in medical treatment, management, and care over the years and the halving of mortality in recent decades, there is considerable room for improvement. Following myocardial infarction (MI), a patient is at great risk for subsequent infarctions or other related complications. In addition, the risk of ischemic stroke is increased following MI. Secondary prevention after MI is paramount for reducing further complications and consists of lifestyle changes, optimised medical treatment, and risk factor control of blood pressure (BP) and blood lipid levels. Although secondary preventive measures are effective, the proportion of patients reaching set treatment target levels is disappointingly low.Most patients are prescribed dual antiplatelet therapy (DAPT) following MI as part of their secondary preventive treatment. Several articles have been published on treatment efficacy based on comparisons with different kinds of antiplatelet drugs and in different combinations. However, little data specifically address the incidence of ischemic stroke after MI in real-world populations. In addition to antiplatelet treatment, secondary prevention comprises risk factor control of hypertension and hyperlipidaemia. Given the low proportion of patients reaching set target levels for BP and blood lipids, new strategies are needed.Aims: The aim of this dissertation is partly to elucidate if the rapid change in preferred DAPT in Sweden, from clopidogrel to ticagrelor in addition to aspirin, affected the incidence of ischemic stroke in patients suffering AMI (paper I) and in patients suffering AMI who have a history of ischemic stroke (paper II).The second part of the dissertation aims to investigate the feasibility and implementation of a randomised controlled trial of a nurse-led telephone-based secondary preventive program, and to assess the proportion of patients who can be included in an unselected acute coronary syndrome (ACS) population (paper III). Furthermore, the aim of the trial was to assess the long term results regarding systolic BP (SBP), diastolic BP (DBP), and low-density lipoprotein cholesterol (LDL-C) after 36 months of intervention and follow-up compared to a control group receiving usual care (paper IV).Methods: Papers I and II examined the impact of a change in the antiplatelet regimen following MI in regard to ischemic stroke occurrence. Data were obtained from the Swedish Register of Information and Knowledge about Swedish Heart Intensive Care Admissions (i.e., RIKS-HIA). The register was combined with the National Patient Register (NPR) and the Cause of Death Register (CDR) in order to obtain data on stroke occurrence. Patients with AMI and treated with either clopidogrel or ticagrelor were assigned to one of two cohorts, each covering a 2- year time period, with the initial prescription of ticagrelor (20 Dec 2011) used as a cutoff point. Patients in the early cohort (n=23,447) were treated exclusively with clopidogrel, whereas those in the later cohort (n=24,227) were treated with either clopidogrel (47.9%) or ticagrelor (52.1%). In paper II, the same methodology was used, but with a study sample restricted to AMI patients with a history of ischemic stroke. In paper II, there were 1633 patients in the early cohort and 1642 in the late cohort. In the late cohort, 66.3% patients were treated with clopidogrel and 33.7% with ticagrelor. Kaplan–Meier analysis was used to assess the risk of ischemic stroke over time, with multivariable Cox regression analysis used to identify predictors of ischemic stroke. Nurse-based Age independent Intervention to Limit Evolution of Disease (Papers III and IV were based on the NAILED)-ACS trial. The NAILED-ACS trial was an open randomised controlled trial of whether a nurse-led telephone-based follow-up and medical titration after MI or unstable angina achieved lower levels of BP and LDL-C than usual care. In paper III, patients admitted for ACS during January 2010 and December 2013 were evaluated for participation. Factors predicting participation and non- participation were assessed using logistic regression. Mortality rates after one year among included and excluded patients and patients declining participation were assessed using Kaplan–Meier analysis. For paper IV, all patients admitted with ACS at Östersund Hospital between January 2010 and December 2014 were screened for inclusion based on their ability to participate in a telephone- based follow-up. Participants were randomised into two parallel groups, an intervention group and a control group receiving usual care. BP and LDL-C were measured at 1, 12, 24, and 36 months. The baseline consisted of randomised patients who completed the one-month follow-up. The intervention group  received counselling and medical titration to attain treatment targets (BP <140/<90 mmHg and LDL-C <2.5/<1.8 mmol/L). Adjusted means stratified by sex and type of ACS were calculated for SBP and DBP and LDL-C. The proportion of patients who achieved treatment target levels at the end of the study was also assessed.Results: Among the general AMI population treated with either clopidogrel or ticagrelor, the incidence of ischemic stroke after one year was 2.8% in the early cohort vs. 2.4% in the late cohort (p=0.001) (paper I). The study population in paper II, in which all patients had a history of previous ischemic stroke, was overall older and had a higher prevalence of comorbidities than the population in paper I. In paper II, incidence of ischemic stroke in the early cohort was 12.1% vs. 8.6% in the late cohort (p<0.01). Corresponding incidence of intracranial bleeding for the population in paper II was a non-significant 1.2% vs 1.5%.In the feasibility study of the NAILED-ACS trial (paper III), 907 patients were assessed for inclusion. Among these, 72.9% could be included (n=661), 146 patients (16.1%) were excluded, and 100 patients declined participation (11 %). Reasons for exclusion were mainly participation in another trial, dementia, inability to use a telephone, and advanced disease. Examples of predictors of both exclusion and declining participation were older age, lower functional status, and lower education. Non-participating patients had significantly higher mortality rates at one year compared to participating patients.Paper IV presents the final results of the NAILED-ACS risk factor trial in which a total of 962 patients were randomised and completed the one-month follow- up. Of this group, 797 were available for analysis after 36 months. Compared to the control group, in the intervention group, mean SBP was 4.1 mmHg lower, mean DBP was 2.9 mmHg lower, and mean LDL-C was 0.28 mmol/L lower (p<0.001 for all). The proportions of patients reaching treatment target goals for SBP, DBP, and LDL-C were significantly higher in the intervention group. In regard to SBP, 77.6% of intervention patients achieved treatment target levels, compared to 62.9% in the control group. Corresponding numbers for DBP were 90.9% vs. 80.8% and for LDL-C, they were 65.6% vs. 53.1%Conclusion: The incidence of ischemic stroke was significantly lower in a cohort of AMI patients following a change in preferred treatment from clopidogrel to ticagrelor (paper I). In AMI patients with a history of ischemic stroke (paper II), the incidence rate of ischemic stroke was significantly lower in the late cohort compared to the early cohort, and overall incidence rates were markedly higher than in paper I.The NAILED-ACS trial was shown to be both feasible (paper III) and successful, with a higher proportion of patients reaching treatment target levels in the intervention group, and significantly lower mean values for SBP, DBP, and LDL- C (paper IV).
  •  
16.
  • Häggström, Daniel, et al. (författare)
  • Optimization of synchronizer cone angle with regard to manufacturing tolerances of cone roundness and cone angle
  • 2020
  • Ingår i: Proceedings of the Institution of mechanical engineers. Part D, journal of automobile engineering. - : SAGE PUBLICATIONS LTD. - 0954-4070 .- 2041-2991. ; 234:2-3, s. 681-688
  • Tidskriftsartikel (refereegranskat)abstract
    • The effects of manufacturing tolerances on the maximum focal temperature has been investigated by transient thermomechanical simulations. Both relative cone angle and cone out-of-roundness for molybdenum and carbon fibre reinforced polymer synchronizers were evaluated. It was shown that cone out-of-roundness significantly increases the focal contact temperature for that specific cone but has little impact on the opposing cone. Two populations of measured synchronizers were evaluated, and it was shown that the maximum focal surface temperature can be decreased in almost all tolerance cases by introducing a relative angle between the cones.
  •  
17.
  • Häggström, Daniel, et al. (författare)
  • Thermomechanical performance of carbon fiber reinforced polymer synchronizer friction liners
  • 2022
  • Ingår i: Proceedings of the Institution of mechanical engineers. Part J, journal of engineering tribology. - : SAGE Publications. - 1350-6501 .- 2041-305X. ; 236:6, s. 1074-1080
  • Tidskriftsartikel (refereegranskat)abstract
    • To improve the ability of a thermomechanical simulation model for carbon fiber reinforced polymer lined synchronizers to predict synchronization performance and reliability, temperature dependent material data for the specific carbon fiber reinforced polymer lining is needed. The compressive modulus, coefficient of thermal expansion, specific heat and thermal conductivity are determined experimentally. The effect of each material property on the focal surface temperature is analyzed, and it is shown that the compressive modulus has the largest influence for all analyzed load cases. Physical tests show that surface hot spots begin to appear at a simulated focal surface temperature of 200 (Formula presented.) C, while performance degradation occurs at a simulated focal surface temperature of 230 (Formula presented.) C–250 (Formula presented.) C. 
  •  
18.
  • Kjellström, Barbro, et al. (författare)
  • Five year risk assessment and treatment patterns in patients with chronic thromboembolic pulmonary hypertension
  • 2022
  • Ingår i: ESC Heart Failure. - : John Wiley & Sons. - 2055-5822. ; 9:5, s. 3264-3274
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims: Repeated risk assessments and treatment patterns over long time are sparsely studied in chronic thromboembolic pulmonary hypertension (CTEPH); thus, we aimed to investigate changes in risk status and treatment patterns in incident patients with CTEPH over a 5 year period.Methods and results: Descriptive and explorative study including 311 patients diagnosed with CTEPH 2008–2019 from the Swedish pulmonary hypertension registry, stratified by pulmonary endarterectomy surgery (PEA). Risk and PH-specific treatment were assessed in surgically treated (PEA) and medically treated (non-PEA) patients at diagnosis and up to 5 years follow-up. Data are presented as median (Q1–Q3), count or per cent. Prior to surgery, 63% in the PEA-group [n = 98, age 64 (51–71) years, 37% female] used PH-specific treatment and 20, 69, and 10% were assessed as low, intermediate or high risk, respectively. After 1 year post-surgery, 34% had no PH-specific treatment or follow-up visit registered despite being alive at 5 years. Of patients with a 5 year visit (n = 23), 46% were at low and 54% at intermediate risk, while 91% used PH-specific treatment. In the non-PEA group [n = 213, age 72 (65–77) years, 56% female], 28% were assessed as low, 61% as intermediate and 11% as high risk. All patients at high risk versus 50% at low risk used PH-specific treatment. The 1 year mortality was 6%, while the risk was unchanged in 57% of the patients; 14% improved from intermediate to low risk, and 1% from high to low risk. At 5 years, 27% had a registered visit and 28% had died. Of patients with a 5 year visit (n = 58), 38% were at low, 59% at intermediate and 1% at high risk, and 86% used PH-specific treatment.Conclusions: Risk status assessed pre-surgery did not foresee long-term post-PEA risk and pre-surgery PH-specific treatment did not foresee long-term post-PEA treatment. Medically treated CTEPH patients tend to remain at the same risk over time, suggesting a need for improved treatment strategies in this group.
  •  
19.
  • Kristan, Matej, et al. (författare)
  • The first visual object tracking segmentation VOTS2023 challenge results
  • 2023
  • Ingår i: 2023 IEEE/CVF International conference on computer vision workshops (ICCVW). - : Institute of Electrical and Electronics Engineers Inc.. - 9798350307443 - 9798350307450 ; , s. 1788-1810
  • Konferensbidrag (refereegranskat)abstract
    • The Visual Object Tracking Segmentation VOTS2023 challenge is the eleventh annual tracker benchmarking activity of the VOT initiative. This challenge is the first to merge short-term and long-term as well as single-target and multiple-target tracking with segmentation masks as the only target location specification. A new dataset was created; the ground truth has been withheld to prevent overfitting. New performance measures and evaluation protocols have been created along with a new toolkit and an evaluation server. Results of the presented 47 trackers indicate that modern tracking frameworks are well-suited to deal with convergence of short-term and long-term tracking and that multiple and single target tracking can be considered a single problem. A leaderboard, with participating trackers details, the source code, the datasets, and the evaluation kit are publicly available at the challenge website1
  •  
20.
  • Kumlien, Christine, et al. (författare)
  • Research priorities to prevent and treat diabetic foot ulcers-A digital James Lind Alliance Priority Setting Partnership
  • 2022
  • Ingår i: Diabetic Medicine. - : John Wiley & Sons. - 0742-3071 .- 1464-5491. ; 39:11
  • Tidskriftsartikel (refereegranskat)abstract
    • Aim To establish outcomes of a priority setting partnership between participants with diabetes mellitus and clinicians to identify the top 10 research priorities for preventing and treating diabetic foot ulcers (DFUs). Methods Due to the COVID-19 pandemic, the James Lind Alliance Priority Setting Partnership process was adapted into a digital format which involved a pilot survey to identify understandable uncertainties with high relevance for participants tested by calculating the content validity index; a main survey answered by 53 participants living with diabetes and 49 clinicians; and a final digital workshop to process and prioritise the final top 10 research priorities. Results The content validity index was satisfactory for 20 out of 25 uncertainties followed by minor changes and one additional uncertainty. After we processed the 26 uncertainties from the main survey and seven current guidelines, a list of 28 research uncertainties remained for review and discussion in the digital workshop. The final top 10 research priorities included the organisation of diabetes care; screening of diabetes, impaired blood circulation, neuropathy, and skin properties; vascular surgical treatment; importance of self-care; help from significant others; pressure relief; and prevention of infection. Conclusion The top 10 research priorities for preventing and treating DFUs represent consensus areas from persons living with diabetes and clinicians to guide future research. These research priorities can justify and inform strategic allocation of research funding. The digitalisation of James Lind Alliance methodology was feasible.
  •  
21.
  • Löbel, Martin, et al. (författare)
  • Microstructure and Corrosion Properties of AlCrFeCoNi High-Entropy Alloy Coatings Prepared by HVAF and HVOF
  • 2022
  • Ingår i: Journal of thermal spray technology (Print). - : Springer. - 1059-9630 .- 1544-1016. ; :1-2, s. 247-255
  • Tidskriftsartikel (refereegranskat)abstract
    • High-entropy alloys (HEAs) represent an innovative development approach for new alloy systems. These materials have been found to yield promising properties, such as high strength in combination with sufficient ductility as well as high wear and corrosion resistance. Especially for alloys with a body-centered cubic (bcc) structure, advantageous surface properties have been revealed. However, typical HEA systems contain high contents of expensive or scarce elements. Consequently, applying them as coatings where their use is limited to the surface represents an exciting pathway enabling economical exploitation of their superior properties. Nevertheless, processing conditions strongly influence the resulting microstructure and phase formation, which in turn has a considerable effect on the functional properties of HEAs. In the presented study, microstructural differences between high-velocity oxygen fuel (HVOF) and high-velocity air fuel (HVAF) sprayed coatings of the alloy AlCrFeCoNi are investigated. A metastable bcc structure is formed in both coating processes. Precipitation reactions are suppressed by the rapid solidification during atomization and by the relatively low thermal input during spraying. The coating resistance to corrosive media was investigated in detail, and an improved passivation behavior was observed in the HVAF coatings. 
  •  
22.
  • Mahade, Satyapal, 1987-, et al. (författare)
  • Incorporation of graphene nano platelets in suspension plasma sprayed alumina coatings for improved tribological properties
  • 2021
  • Ingår i: Applied Surface Science. - : Elsevier BV. - 0169-4332 .- 1873-5584. ; 570
  • Tidskriftsartikel (refereegranskat)abstract
    • Graphene possesses high fracture toughness and excellent lubrication properties, which can be exploited to enhance tribological performance of coating systems utilized to combat wear. In this work, suspension plasma spray (SPS) process was employed to deposit a composite, graphene nano-platelets (GNP) incorporated alumina coating. For comparison, monolithic alumina was also deposited utilizing identical spray conditions. The as-deposited coatings were characterized in detail for their microstructure, porosity content, hardness, fracture toughness and phase composition. Raman analysis of the as-deposited composite coating confirmed retention of GNP. The composite coating also showed good microstructural integrity, comparable porosity, higher fracture toughness and similar alumina phase composition as the monolithic alumina coating. The as-deposited coatings were subjected to dry sliding wear tests. The GNP incorporated composite coating showed lower CoF and lower specific wear rate than the pure alumina coating. Additionally, the counter surface also showed a lower wear rate in case of the composite coating. Post-wear analysis performed by SEM/EDS showed differences in the coating wear track and in the ball wear track of monolithic and composite coatings. Furthermore, Raman analysis in the wear track of composite coating confirmed the presence of GNP. The micro-indentation and wear test results indicate that the presence of GNP in the composite coating aided in improving fracture toughness, lowering CoF and specific wear rate compared to the monolithic coating. Results from this work demonstrated retention of GNP in an SPS processed coating, which can be further exploited to design superior wear-resistant coatings.
  •  
23.
  • Mahade, Satyapal, 1987-, et al. (författare)
  • Influence of processing conditions on the microstructure and sliding wear of a promising Fe-based coating deposited by HVAF
  • 2021
  • Ingår i: Surface & Coatings Technology. - : Elsevier. - 0257-8972 .- 1879-3347. ; 409, s. 1-17
  • Tidskriftsartikel (refereegranskat)abstract
    • Thermal spray is a versatile and cost-effective process to deposit wear and corrosion resistant coatings. In this work, a relatively new ‘Fe-based’ chemistry comprising boride and carbides, is explored as a ‘greener’ alternative to the relatively expensive and carcinogenic Co-based coatings to mitigate wear. The emergent thermal spray process of high-velocity air-fuel (HVAF) spraying was chosen to deposit the Fe-based coatings, with the high-velocity oxy-fuel (HVOF) also being employed solely for the purpose of preliminary comparison. Detailed characterization of the HVOF and HVAF sprayed Fe-based coatings was carried out. Microstructure, porosity, hardness and phase analysis results demonstrate the influence of processing conditions, where specific spray conditions yielded minimal undeformed particulates content, high hardness, low porosity and feedstock phase retention. Differences in microstructural features of the as-deposited coatings in relation to their processing conditions are discussed in detail. The coatings were subjected to ball-on-disc tribometry tests at different load conditions and their friction and wear performance were evaluated. The coefficient of friction results of investigated coatings concurred with their respective microstructural features. Post-mortem of the worn coating surface, the mating alumina ball surface and wear debris was performed using SEM/EDS analysis to understand the associated wear mechanisms and material transfer. This work provides new insights on identifying appropriate HVAF processing conditions to achieve acceptable microstructural features and phases in Fe-based coatings for improved wear performance.
  •  
24.
  • Mahade, Satyapal, 1987-, et al. (författare)
  • Investigating Load-dependent Wear Behavior and Degradation Mechanisms in Cr3C2-NiCr coatings deposited by HVAF and HVOF
  • 2021
  • Ingår i: Journal of Materials Research and Technology. - : Elsevier BV. - 2238-7854. ; 15, s. 4595-4609
  • Tidskriftsartikel (refereegranskat)abstract
    • Wear resistant coatings that comply with non-toxic environment goals are highly desirable. Cr3C2-NiCr is a promising alternative to the toxic, ‘Co’- containing WC-Co coatings to mitigate wear. The purpose of this study was to examine the suitability of Cr3C2-NiCr coatings for automotive brake disc application by systematically investigating their dry sliding wear behavior at different test conditions. Therefore, High Velocity Air Fuel (HVAF) and High Velocity Oxy Fuel (HVOF) were employed to deposit Cr3C2-NiCr coatings. The powder feedstock and as-deposited Cr3C2-NiCr coatings were characterized for their microstructure and phase composition using SEM and XRD. Mechanical properties (hardness, fracture toughness), porosity and surface topography of the as-deposited coatings were evaluated. The coatings were subjected to sliding wear tests at different normal loads (5 N, 10 N and 15 N) using alumina ball as the counter surface. Coefficient of friction (CoF) evolution of HVAF and HVOF deposited coatings, along with their wear performance, was obtained for different normal load conditions. The wear performance ranking of HVAF and HVOF processed coatings was influenced by the test conditions, with HVAF coatings demonstrating better wear resistance than HVOF coatings at harsh test conditions and the HVOF coatings performing better under mild wear test conditions. Detailed post-wear analysis of worn coatings, the alumina ball counter-body and the resulting debris was performed to reveal the degradation mechanisms at different test conditions. Findings from this work provide new insights into the desirable microstructural features to mitigate wear, which can be further exploited to deposit wear-resistant coatings.
  •  
25.
  • Mahade, Satyapal, 1987-, et al. (författare)
  • Novel suspension route to incorporate graphene nano-platelets in HVAF-sprayed Cr3C2-NiCr coatings for superior wear performance
  • 2021
  • Ingår i: Journal of Materials Research and Technology. - : Elsevier BV. - 2238-7854. ; 13, s. 498-512
  • Tidskriftsartikel (refereegranskat)abstract
    • Graphene nano platelets (GNP) have several attractive properties, including excellent lubricity that can be used to develop wear-resistant coatings. Thermally sprayed chromium carbide-nickel chromium (Cr3C2-NiCr) coatings are widely employed to impart wear resistance to engineering components. This work attempts to improve the wear resistance of high velocity air fuel (HVAF) sprayed Cr3C2-NiCr coatings by incorporating GNP using a hybrid approach in which Cr3C2-NiCr (powder) and GNP (suspension) are co-axially injected. Two different powder-to-suspension delivery ratios were employed in this study that utilizes a liquid feedstock in tandem with a HVAF system. Furthermore, for comparison, a pure (without graphene) Cr3C2-NiCr reference coating was deposited by the HVAF process using identical spray parameters. The as-sprayed coatings were characterized for their microstructure and phase constitution by SEM/EDS and X-Ray Diffraction. Mechanical properties such as hardness and fracture toughness were evaluated using micro-indentation technique. The hybrid coatings were subjected to dry sliding wear tests and wear performance was compared with reference Cr3C2-NiCr. The GNP incorporated hybrid coatings exhibited lower CoF and lower wear rates than the reference Cr3C2-NiCr coating. Post wear SEM/EDS analysis revealed different wear mechanisms predominant in the investigated coatings. Utilizing the above as a case study, this work provides key insights into a new approach to produce GNP incorporated coatings for mitigating wear.
  •  
26.
  • Mahade, Satyapal, 1987-, et al. (författare)
  • Novel utilization of powder-suspension hybrid feedstock in HVAF spraying to deposit improved wear and corrosion resistant coatings
  • 2021
  • Ingår i: Surface & Coatings Technology. - : Elsevier. - 0257-8972 .- 1879-3347. ; 412
  • Tidskriftsartikel (refereegranskat)abstract
    • Deployment of a suspension feedstock has been known to alleviate problems associated with using sub-micron and nanosized powder feedstock for thermal spraying of monolithic as well as powder-suspension ‘hybrid’ composite coatings. However, a powder-suspension hybrid feedstock has never been previously used in high-velocity air-fuel (HVAF) spraying. In this work, for the very first time, a chromium carbide (Cr3C2) suspension has been co-sprayed along with an Inconel-625 (IN-625) powder by the HVAF process as an illustrative case study. Two variants of the IN-625 + Cr3C2 hybrid coatings were produced by varying relative powder-suspension feed rates. For comparison, pure IN-625 coating was also deposited utilizing identical spray parameters. Detailed microstructural characterization, porosity content, hardness measurement and phase analysis of the as-deposited coatings was performed. The suspension-derived carbides were retained in the bulk of the coating, resulting in higher hardness. In the dry sliding wear test, the hybrid coatings demonstrated lower wear rate and higher coefficient of friction (CoF) compared to the conventional, powder-derived IN-625 coatings. Furthermore, the wear rate improved slightly with an increase in Cr3C2 content in the hybrid coating. Post-wear analysis of the worn coating, worn alumina ball and the wear debris was performed to understand the wear mechanisms and material transfer in the investigated coatings. In the potentiodynamic polarization test, higher corrosion resistance for hybrid coatings than conventional IN-625 coatings was achieved, indicating that the incorporation of a secondary, carbide phase in the IN-625 matrix did not compromise its corrosion performance. This work demonstrates a novel approach to incorporate any finely distributed second phase in HVAF sprayed coatings to enhance their performance when exposed to harsh environments.
  •  
27.
  • Mahade, Satyapal, 1987-, et al. (författare)
  • Novel wear resistant carbide-laden coatings deposited by powder-suspension hybrid plasma spray : Characterization and testing
  • 2020
  • Ingår i: Surface & Coatings Technology. - : Elsevier BV. - 0257-8972 .- 1879-3347. ; 399
  • Tidskriftsartikel (refereegranskat)abstract
    • Thermal spraying with a hybrid powder-suspension feedstock presents a novel approach to conveniently realize coatings with unusual chemistries and unique microstructures. In this study, coatings were deposited by simultaneous spraying of T-400 (Tribaloy-400) powder and Cr3C2 suspension with varying relative feed rates. For comparison, pure T-400 coating was also deposited using powder feedstock via atmospheric plasma spray (APS) route to assess the role of incorporating a hard, finely distributed carbide phase in the coating. SEM (Scanning electron microscopy)/EDS (Energy-dispersive X-ray spectroscopy) investigation of the hybrid coatings revealed a lamellar microstructure with distributed fine carbides. XRD (X-ray diffraction) analysis of the feedstock and hybrid coatings showed the presence of original feedstock constituents, along with some oxides of chromium, in the deposited coating. Hardness measurements on the as-sprayed coatings indicated higher hardness in hybrid coatings than in the pure T-400 coating. The deposited coatings were subjected to scratch testing on polished surfaces as well as on polished cross sections. The scratching response of the coatings was examined by SEM analysis. Results demonstrated that the hybrid coatings possess excellent scratch resistance, superior compared to the pure T-400 coating, which is promising for extending the durability of engineering components operating under severe wear conditions. This was confirmed by abrasion test results which established the superior wear resistance of hybrid coatings. The above hybrid approach is easily extendable to other material systems and can have important implications in the realization of next-generation wear resistant coatings. © 2020 Elsevier B.V.
  •  
28.
  • Mahade, Satyapal, 1987-, et al. (författare)
  • Sliding wear behavior of a sustainable Fe-based coating and its damage mechanisms
  • 2022
  • Ingår i: Wear. - : Elsevier. - 0043-1648 .- 1873-2577. ; 500-501
  • Tidskriftsartikel (refereegranskat)abstract
    • The current industry demand is to identify suitable alternatives to the risk-of-supply prone and/or toxic, WC-Co and electrolytic hard chrome coatings without comprising the desired wear performance. Therefore, compositions based on abundantly available elements (e.g. ‘Fe’) that possess adequate wear resistance are desirable from health, sustainability and economic standpoints. In this work, crystalline Fe-based (Rockit-401) coatings were processed using two different thermal spray routes, i.e. HVOF and HVAF spraying. The influence of deposition route and processing conditions on the microstructure, porosity content, hardness and phase composition was examined. The as-deposited coatings were subjected to mild (5 N) and harsh (15 N) dry sliding wear test conditions by employing alumina ball as the counter surface material, and their wear performance was examined. Mild sliding wear test conditions (5 N) resulted in anomalous wear behavior, where the abrupt drop in CoF at several instances during the test was observed in all the investigated coatings. On the other hand, under harsh wear test conditions (15 N), such an abrupt dip in CoF was not observed. Detailed wear mechanisms of the coatings were revealed under different test conditions (5 N and 15 N). This work sheds light on processing, wear behavior and wear mechanisms of a sustainable and high-performance coating that fulfills non-toxic and sustainability goals in tandem for tribological applications. © 2022 The Authors
  •  
29.
  • Mahade, Satyapal, 1987-, et al. (författare)
  • Tailoring microstructure of double-layered thermal barrier coatings deposited by suspension plasma spray for enhanced durability
  • 2021
  • Ingår i: Surface & Coatings Technology. - : Elsevier B.V.. - 0257-8972 .- 1879-3347. ; 425
  • Tidskriftsartikel (refereegranskat)abstract
    • Gadolinium zirconate (GZ)-based TBCs comprising GZ as the top layer and yttria stabilized zirconia (YSZ) as the base layer, are attractive double-layered thermal barrier coatings (TBCs) for high temperature gas turbine engine application. This work attempts to understand the influence of individual layer microstructure on the durability of GZ/YSZ double-layered TBCs processed by suspension plasma spray (SPS). Two different spray parameters were chosen to obtain a combination of three microstructurally distinct GZ/YSZ double-layered TBCs i.e. GZ porous (P)/YSZ porous (P), GZ dense (D)/YSZ porous (P) and GZ dense (D)/YSZ dense (D). Thermal diffusivity of the as-deposited coatings was measured using Laser Flash Analysis (LFA) technique and the thermal conductivity of the TBCs was calculated. The GZ/YSZ double-layered TBC specimens were subjected to two different durability tests, i.e. thermal cyclic fatigue (TCF) and burner rig test (BRT). Sintering behavior of the individual layer TBC microstructures was evaluated by comparing the porosity evolution in as-deposited and TCF tested TBCs. Fracture toughness measurements performed on each layer of the double-layered TBCs were correlated with the durability results. Thermal cycling results amply demonstrate that the individual layer microstructure of GZ/YSZ double-layered TBC influenced its durability. Detailed failure analysis of the TCF and BRT failed specimens revealed similar failure modes for GZ (P)/YSZ (P), GZ (D)/YSZ (P) and GZ (D/YSZ (D) TBCs under identical thermal cyclic test conditions. However, failure modes differed when subjected to different thermal cyclic test conditions (TCF and BRT) and the probable causes are discussed. Findings from this work provide key insights on designing durable GZ/YSZ double-layered TBCs.
  •  
30.
  • Mathiyalagan, Sribalaji, et al. (författare)
  • Deposition characteristics and tribological performance of atmospheric plasma sprayed diamond metal matrix composite (DMMC) coatings
  • 2024
  • Ingår i: Materials Chemistry and Physics. - : Elsevier Ltd. - 0254-0584 .- 1879-3312. ; 315
  • Tidskriftsartikel (refereegranskat)abstract
    • Diamond-reinforced metal matrix composites (DMMC) have great potential for wear-resistance applications due to the superior hardness imparted by diamond. Atmospheric plasma spraying involving axial injection of suitable feedstock is a convenient pathway to fabricate DMMC coatings for tribological applications. In this paper, thick DMMC coatings were deposited by plasma spraying Ni–P clad diamond particles under varying spray conditions. It was found that the phase characteristics of DMMC coatings as well as extent of diamond retention and fragmentation were significantly influenced by spray conditions such as, stand-off distance (SOD) and carrier gas flow rate (CGFR). Mechanical characterization (by micro-indentation) on all DMMC coatings developed in this work showed that coatings sprayed with longer SOD and higher CGFR has relatively higher hardness than other two coatings. However, on nanoindentation, the diamond hardness was found overestimated due to effect of diamond roughness on fragmentation. Ball-on-disc wear testing showed excellent tribological properties in all cases, with enhanced wear performance being noted when more diamond is retained in the coating. © 2024
  •  
31.
  • Mathiyalagan, Sribalaji, et al. (författare)
  • High velocity air fuel (HVAF) spraying of nickel phosphorus-coated cubic-boron nitride powders for realizing high-performance tribological coatings
  • 2022
  • Ingår i: Journal of Materials Research and Technology. - : Elsevier Editora Ltda. - 2238-7854. ; 18, s. 59-74
  • Tidskriftsartikel (refereegranskat)abstract
    • High velocity air fuel (HVAF) spraying is an emergent thermal spray process, which is used in this work to realize high-performance large area tribological coatings of nickel-phosphorus cladded cubic-boron nitride (c-BN) particles. To the best of authors’ knowledge, this is the first time that HVAF has been utilized for developing Ni–P coatings reinforced with c-BN (NBN). The importance of appropriate processing was highlighted by utilizing two different nozzle configurations, for which microstructure, phase analysis and hardness results demonstrates considerable differences. Furthermore, the coatings were subjected to sliding wear tests to assess their friction and wear characteristics. Post-wear SEM analysis reveals the associated wear mechanisms. Effect of annealing on tribological performance of NBN coatings was also examined, and it is shown that optimal processing can preclude the need for post-treatment. Results ensuing from this work lay the foundation for new generation of HVAF-sprayed wear resistant metal/c-BN composite coatings for diverse applications. © 2022 The Author(s)
  •  
32.
  • Meghwal, Ashok, et al. (författare)
  • Novel Al2CoCrFeNi high-entropy alloy coating produced using suspension high velocity air fuel (SHVAF) spraying
  • 2023
  • Ingår i: Intermetallics. - : Elsevier. - 0966-9795. ; 163, s. 1-4
  • Tidskriftsartikel (refereegranskat)abstract
    • Metallic coatings of Al2CoCrFeNi high entropy alloy (HEA) were deposited using the suspension high velocity air fuel spray (SHVAF) process, towards exploring its viability as a bond coat in thermal barrier coatings. The relatively high Al content promoted a BCC + B2 phase-dominated coating structure, leading to enhanced mechanical properties. The oxidized microstructure exhibited a protective Al2O3 layer with characteristics comparable to conventional bond coat alloys. 
  •  
33.
  • Michalak, Monika, et al. (författare)
  • Wear Behavior Analysis of Al2O3 Coatings Manufactured by APS and HVOF Spraying Processes Using Powder and Suspension Feedstocks
  • 2021
  • Ingår i: Coatings. - : MDPI. - 2079-6412. ; 11:8
  • Tidskriftsartikel (refereegranskat)abstract
    • Thermally sprayed ceramic coatings are applied for the protection of surfaces that are exposed mainly to wear, high temperatures, and corrosion. In recent years, great interest has been garnered by spray processes with submicrometric and nanometric feedstock materials, due to the refinement of the structure and improved coating properties. This paper compares the microstructure and tribological properties of alumina coatings sprayed using conventional atmospheric plasma spraying (APS), and various methods that use finely grained suspension feedstocks, namely, suspension plasma spraying (SPS) and suspension high-velocity oxy-fuel spraying (S-HVOF). Furthermore, the suspension plasma-sprayed Al2O3 coatings have been deposited with radial (SPS) and axial (A-SPS) feedstock injection. The results showed that all suspension-based coatings demonstrated much better wear resistance than the powder-sprayed ones. S-HVOF and axial suspension plasma spraying (A-SPS) allowed for the deposition of the most dense and homogeneous coatings. Dense-structured coatings with low porosity (4 vol.%) and good cohesion to the metallic substrate, containing a high content of alpha-Al2O3 phase (56 vol.%) and a very low wear rate (0.2 +/- 0.04 mm(3) x 10(-6)/(N center dot m)), were produced with the S-HVOF method. The wear mechanism of ceramic coatings included the adhesive wear mode supported by the fatigue-induced material delamination. Moreover, the presence of wear debris and tribofilm was confirmed. Finally, the coefficient of friction for the coatings was in the range between 0.44 and 0.68, with the highest values being recorded for APS sprayed coatings.
  •  
34.
  • Mulone, Antonio, 1989, et al. (författare)
  • Development of yttria-stabilized zirconia and graphene coatings obtained by suspension plasma spraying: Thermal stability and influence on mechanical properties
  • 2023
  • Ingår i: Ceramics International. - : Elsevier BV. - 0272-8842 .- 1873-3956. ; 49:6, s. 9000-9009
  • Tidskriftsartikel (refereegranskat)abstract
    • This study investigated the feasibility of depositing graphene nanoplatelet (GNP)-reinforced yttria-stabilized zirconia (YSZ) composite coatings. The coatings were deposited from an ethanol-based mixed YSZ and GNP suspension using suspension plasma spraying (SPS). Raman spectroscopy confirmed the presence of GNPs in the YSZ matrix, and scanning electron microscopy (SEM) analysis revealed a desired columnar microstructure with GNPs distributed predominantly in the inter-columnar spacing of the YSZ matrix. The as-deposited YSZ-GNP coatings were subjected to different isothermal treatments—400, 500, and 600 °C for 8 h—to study the thermal stability of the GNPs in the composite coatings. Raman analysis showed the retention of GNPs in specimens exposed to temperatures up to 500 °C, although the defect concentration in the graphitic structure increased with increasing temperature. Only a marginal effect on the mechanical properties (i.e., hardness and fracture toughness) was observed for the isothermally treated coatings.
  •  
35.
  • Nilsson, Miriam, 1984- (författare)
  • Studies of the chromatin form of yeast Mediator and the function of its tail module
  • 2023
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Mediator is a large, multifunctional complex that is conserved in eukaryotes. It was first discovered in Saccharomyces cerevisiaeas required for transcriptional activators to function in a reconstituted in vitro system. Mediator is also important for stimulation of basal, unregulated transcription, and transcriptional repression. In yeast, Mediator consists of 25 subunits divided into head, middle, and tail modules, and is intermittently associated with a Cdk8 kinase module (CKM). The head and middle bind to the RNA polymerase II (Pol II) while the tail is responsible for binding to gene-specific transcriptional regulators. Most head and middle subunits are essential, whereas all tail module subunits are encoded by non-essential genes. CKM is mostly involved in transcriptional repression by binding Mediator in a way that sterically blocks the binding of Pol II to Mediator. Mediator is traditionally purified from the ‘non-chromatin’ fraction of whole-cell extracts. Since most Mediator functions occur in a chromatin context, we set out to purify Mediator from the chromatin fraction of cell extracts. We performed affinity-purification using strains expressing epitope-tagged Mediator subunits, combined with mass spectrometry to reveal the composition of chromatin-bound Mediator. We found that Mediator in chromatin interacts with several protein complexes involved in different aspects of gene expression. Several of them, such as CPF, CF IA, and TFIIB have been shown to be involved in gene looping. Using Chromatin immunoprecipitation (ChIP)-seq experiments, we localized Mediator occupancy genome-wide. As expected, we found enrichment of Mediator at gene promoters, but also at Chromatin Interaction Domain boundaries (CIDBs), which are important for chromatin organization and transcriptional regulation. We also investigated the yeast Tail module function in detail. Individually, Tail subunit mutants are non-essential, but med15/med16 or med5/med15 strain are lethal. We used the N-degron system to conditionally deplete Med15/Med16 or Med5/Med15 and studied their effects on global gene expression using MicroArray assays. Several meiosis and sporulation genes were upregulated in the med5/med15 and med15/med16. In support of this, Rck1 which is a repressor of meiosis and sporulation rate in diploid cells, was downregulated in both strains. All strains where Med15 expression was depleted showed downregulation of several target genes for the Ace2 transcription factor which is important for cell cycle progression through the G1 cell cycle phase. Accordingly, all our med15-degron strains showed a G1-phase arrest in flow cytometry assays. Finally, we investigated the tail module subunit Med2 which has a phosphorylation site at position S208. We found that point mutations of S208A led to downregulation of several genes that are usually expressed during anaerobic growth. We also found that a med2 strain was unable to grow under anaerobic conditions.
  •  
36.
  • Owoseni, Tunji A., et al. (författare)
  • Microstructure and Tribological Performance of HVAF-Sprayed Ti-6Al-4V Coatings
  • 2023
  • Ingår i: Coatings. - : MDPI. - 2079-6412. ; 13:11, s. 1-15
  • Tidskriftsartikel (refereegranskat)abstract
    • Ti-6Al-4V is a widely used titanium alloy in aviation and bio/chemical applications for its attractive mechanical and corrosion resistance properties. The use of Ti-6Al-4V as a coating for repair purposes through thermal spray techniques provides a unique productivity opportunity. A repair coating must be dense to provide the required in-service functionalities, such as resistance to wear. The High Velocity Air Fuel (HVAF) thermal spray technique deposits dense coatings with reduced concern for oxide inclusions. This work presents an investigation of the microstructure, dry sliding, and solid particle erosive wear performance of four different coatings engineered through the configuration of the nozzle of an HVAF spray gun, based on the length of the nozzle and the size of the nozzle exit. A long nozzle length and wide nozzle exit mean increased inflight dwell time and reduced average inflight temperature for the sprayed particles, respectively—a reversed configuration means the opposite. The tested coatings showed a porosity of less than 2%. The sliding and erosion wear performance of the densest of the coatings compares to that of the bulk material tested under the same conditions. Electron microscopy was used to investigate the driving mechanisms for the performance of the respective coatings. The implications of the results are discussed for the potential adoption of HVAF-sprayed coatings in metal component repair.
  •  
37.
  • Rossetti, Matteo, et al. (författare)
  • Advanced diamond-reinforced metal matrix composite (DMMC) coatings via HVAF process : Effect of particle size and nozzle characteristics on tribological properties
  • 2023
  • Ingår i: Ceramics International. - : Elsevier. - 0272-8842 .- 1873-3956. ; 49:11 Part A, s. 17838-17850
  • Tidskriftsartikel (refereegranskat)abstract
    • High-velocity air fuel (HVAF) spraying is a versatile and cost-effective platform to fabricate wear resistant coatings. In this work, deposition of Nickel–Phosphorus cladded diamond feedstock is explored as a greener alternative to realize highly wear resistant large-area coatings. To the best of authors knowledge. this is the first study that has utilized HVAF technique for developing wear resistant Ni–P coatings reinforced with diamond (NCD). This work also aims to understand the effect of particle size by using coarse (20–30 μm) and fine NCD (10–15 μm) particles as feedstock. The importance of utilizing appropriate processing conditions was also highlighted by using two different nozzle configurations, for which the two powder particle sizes exhibited considerable differences in terms of microstructure, phase characteristics and mechanical properties. Further, the effect of annealing on the above coating characteristics was also examined, and it is shown that optimal spraying conditions can preclude the need for post-treatment. Furthermore, the as-deposited and annealed coatings were subjected to sliding wear tests to assess their tribological performance. Post-wear analysis performed on worn surfaces revealed the associated wear mechanisms. The results ensuing from this work lay the foundation for realizing new generation of HVAF sprayed wear resistant Ni–P/diamond composite coatings for diverse applications.
  •  
38.
  • Sädbom, Stefan, et al. (författare)
  • The use of systematic sampling and XRF-XRT based scanning to determine potential recovery of metals from waste rock
  • 2020
  • Ingår i: Mine Water Solutions. - : International Mine Water Association. - 9783000672972 ; , s. 146-151
  • Konferensbidrag (refereegranskat)abstract
    • It is difficult to evaluate the potential for reprocessing and extraction of minerals from waste rock with valuable and/or harmful elements.We suggest a new sampling strategy/protocol for waste rock, specifically developed for historic mining sites, in combination with XRF-XRT scanning with a GeoCore X10 instrument.Håkansboda historical mine site in Sweden was used as a case study to look at the potential for the combination of techniques.The combination of the suggested randomized sampling strategy/protocol and the dataset from the GX10 scanning enables prediction of amenability for pre-processing with the use of mechanical sorting or if the extraction of valuable minerals only can be achieved through fine grinding, flotation or leaching.
  •  
39.
  • Testa, Veronica, et al. (författare)
  • Micromechanical behaviour and wear resistance of hybrid plasma-sprayed TiC reinforced Tribaloy-400
  • 2021
  • Ingår i: Surface & Coatings Technology. - : Elsevier. - 0257-8972 .- 1879-3347. ; 425
  • Tidskriftsartikel (refereegranskat)abstract
    • Cobalt-based alloys such as Tribaloy-400 are known for their sliding wear resistance at room as well as elevated temperature. However, further enhancement in terms of hardness and wear resistance could be achieved by creating metal matrix composites reinforced by ceramic particles. For this purpose, Tribaloy-400 based coatings were deposited with the addition of different amounts of TiC reinforcement (≈25 vol%, ≈40 vol%, ≈60 vol%) through a “hybrid” plasma spray process, using a dry Tribaloy-400 powder with 10–45 μm particle size and a water-based TiC suspension (d50 = 2.2 μm). Pure Tribaloy and pure TiC coatings were employed for comparison. During spraying, TiC was partly oxidized but could nonetheless be embedded between the bigger Tribaloy-400 lamellae. Specifically, the coating containing ≈ 25 vol% TiC shows a homogeneous microstructure, whilst greater amounts of hard phase lead to some agglomeration. Accordingly, the coating with 25 vol% TiC exhibits a good combination of hardness and toughness (the latter being assessed by scratch testing) and low sliding wear rates of ≈10−5–10−6 mm3/(N·m) from room temperature up to 700 °C in ball-on-disc tests against an Al2O3 counterbody. At room temperature, the tribological behaviour of the coatings is controlled by abrasive grooving and spallation due to surface fatigue. With increasing temperature, tribochemical phenomena take on an ever-increasing role and, at 700 °C, a uniform, oxide-based tribofilm is developed, so that the wear rates are often lower than are recorded at 400 °C.
  •  
40.
  • Torkashvand, Kaveh, 1990-, et al. (författare)
  • Influence of nozzle configuration and particle size on characteristics and sliding wear behaviour of HVAF-sprayed WC-CoCr coatings
  • 2021
  • Ingår i: Surface & Coatings Technology. - : Elsevier BV. - 0257-8972 .- 1879-3347. ; 423, s. 127585-127585
  • Tidskriftsartikel (refereegranskat)abstract
    • In this study, effect of feedstock particle size and nozzle configuration on deposition, microstructural features, hardness and sliding wear behaviour of high velocity air fuel (HVAF)-sprayed WC-CoCr coatings was evaluated. Three different WC-CoCr powders with nominal particle sizes of 5/20 μm (fine), 5/30 μm (medium) and 15/45 μm (coarse) were sprayed employing a HVAF gun with four distinct DeLaval nozzle configurations involving different lengths and/or exit diameters. Microstructure, phase constitution and mechanical characteristics of the coatings were evaluated using SEM, EDS, XRD and micro indentation testing. Specific wear rate for all the samples was determined under sliding conditions and a comprehensive post wear analysis was conducted. X-ray diffraction analysis showed negligible decarburization in all the HVAF-sprayed coatings. It was shown that decrease in particle size of employed feedstock results in discernible changes in microstructural features of the coatings as well as considerable improvement in their performance. Also, notable changes in wear mechanisms were identified on reducing particle size from coarse to medium or fine. Fine and coarse feedstock powders were found to be sensitive to the type of nozzle used while no major difference was observed in coatings from powders with medium cut size sprayed with different nozzles. 
  •  
41.
  • Torkashvand, Kaveh, 1990-, et al. (författare)
  • Tribological Performance of Thin HVAF-Sprayed WC-CoCr Coatings Fabricated Employing Fine Powder Feedstock
  • 2023
  • Ingår i: Journal of thermal spray technology (Print). - : Springer. - 1059-9630 .- 1544-1016. ; 32, s. 1033-1046
  • Tidskriftsartikel (refereegranskat)abstract
    • In this study, sliding and abrasion wear performance of WC-CoCr coatings deposited by high velocity air–fuel (HVAF) spraying with various thicknesses (i.e., 240, 150, 100, 50 and 30 µm), fabricated from fine feedstock powder (5–15 µm), were evaluated. The main aim was to investigate how thinner coatings (30 and 50 µm) perform compared to conventional thick coatings (> 100 µm), in an effort to address the supply and cost concerns associated with Co and W.The feedstock powder and deposited coatings were characterized in terms of microstructure. The hardness of the thin and thick coatings was measured using Vickers hardness method from both cross section and top-surface. It was found that, regardless of the thickness, extremely dense coatings with very high hardness ( 1500 HV) can be deposited employing HVAF and fine feedstock powder. Thin and thick coatings were found to perform similarly under sliding wear with a normal load of 10 N or lower as well as under abrasion wear conditions which highlights the possibility of employing thinner coatings for a majority of the real applications.The results suggest that peening effect does not have a considerable influence on the microstructure or performance of the deposited coatings. However, for sliding wear tests with a 20 N normal load, it was noticed that wear resistance of the coatings slightly declines with decreasing thickness of the coating beyond 150 µm. The main reason was identified to be the involvement of substrate effect when performing tests under severe Hertzian contact pressure.  
  •  
42.
  • Völz, Sebastian, et al. (författare)
  • Survival of Patients With Angina Pectoris Undergoing Percutaneous Coronary Intervention With Intracoronary Pressure Wire Guidance
  • 2020
  • Ingår i: Journal of the American College of Cardiology. - : Elsevier BV. - 0735-1097 .- 1558-3597. ; 75:22, s. 2785-2799
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Intracoronary pressure wire measurement of fractional flow reserve (FFR) provides decision-making guidance during percutaneous coronary intervention (PCI). However, limited data exist on the effect of FFR on long-term clinical outcomes in patients with stable angina pectoris. Objectives: The purpose of this study was to determine the association between the usage of FFR and all-cause mortality in patients with stable angina undergoing PCI. Methods: Data was used from the SCAAR (Swedish Coronary Angiography and Angioplasty Registry) on all patients undergoing PCI (with or without FFR guidance) for stable angina pectoris in Sweden between January 2005 and March 2016. The primary endpoint was all-cause mortality, and the secondary endpoints were stent thrombosis (ST) or restenosis and peri-procedural complications. The primary model was multilevel Cox proportional hazards regression adjusted with Kernel-based propensity score matching. Results: In total, 23,860 patients underwent PCI for stable angina pectoris; of these, FFR guidance was used in 3,367. After a median follow-up of 4.7 years (range 0 to 11.2 years), the FFR group had lower adjusted risk estimates for all-cause mortality (hazard ratio: 0.81; 95% confidence interval [CI]: 0.73 to 0.89; p < 0.001), and ST and restenosis (hazard ratio: 0.74; 95% CI: 0.57 to 0.96; p = 0.022). The number of peri-procedural complications did not differ between the groups (adjusted odds ratio: 0.96; 95% CI: 0.77 to 1.19; p = 0.697). Conclusions: In this observational study, the use of FFR was associated with a lower risk of long-term mortality, ST, and restenosis in patients undergoing PCI for stable angina pectoris. This study supports the current European and American guidelines for the use of FFR during PCI and shows that intracoronary pressure wire guidance confers prognostic benefit in patients with stable angina pectoris.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-42 av 42
Typ av publikation
tidskriftsartikel (36)
konferensbidrag (3)
doktorsavhandling (2)
bokkapitel (1)
Typ av innehåll
refereegranskat (40)
övrigt vetenskapligt/konstnärligt (2)
Författare/redaktör
Björklund, Stefan, 1 ... (29)
Joshi, Shrikant V., ... (26)
Björklund, Stefan (5)
Markocsan, Nicolaie, ... (4)
Sellgren, Ulf (2)
Vergara, Alexander (2)
visa fler...
Blomberg, Jeanette (2)
Fröbert, Ole, 1964- (1)
Abdel-Fattah, Wael R ... (1)
Carlsson, Mattias (1)
Hu, Guo-Zhen (1)
Singh, Ajeet (1)
Aslam, Rameen (1)
Ronne, Hans (1)
Wiklund, Urban (1)
Wang, Fei (1)
Johansson, R. (1)
Mayer, Christoph (1)
Wang, Dong (1)
Redfors, Björn (1)
Acosta, Stefan (1)
Kumlien, Christine (1)
Granlund, Mats, 1954 ... (1)
Hartl, M. (1)
Adli, Erik (1)
Gjersdal, Håvard (1)
Sjøbæk, Kyrre N. (1)
Christoforo, Grey (1)
Fackelman, Eric D. (1)
Røhne, Ole M. (1)
Ringnes, Jonas S. (1)
Solbak, Simen R. (1)
Lithun, Maren C. (1)
Thomas, Cyrille (1)
Levinsen, Yngve (1)
Rosengren, Kaj (1)
Shea, Thomas (1)
Bell, Gerard (1)
Ibison, Mark (1)
Erlinge, David (1)
Björklund, Fredrik (1)
Chen, Yan (1)
Björklund, Stefan, P ... (1)
James, Stefan, 1964- (1)
Götberg, Matthias (1)
Li, Xin (1)
Rådegran, Göran (1)
Bouzina, Habib (1)
Björklund, Johanna, ... (1)
Jensen, Jens (1)
visa färre...
Lärosäte
Högskolan Väst (29)
Umeå universitet (7)
Chalmers tekniska högskola (7)
Uppsala universitet (5)
Lunds universitet (4)
Kungliga Tekniska Högskolan (2)
visa fler...
Örebro universitet (2)
Linköpings universitet (2)
Malmö universitet (2)
Karolinska Institutet (2)
Göteborgs universitet (1)
Jönköping University (1)
Högskolan Dalarna (1)
visa färre...
Språk
Engelska (42)
Forskningsämne (UKÄ/SCB)
Teknik (31)
Naturvetenskap (8)
Medicin och hälsovetenskap (6)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy