| 1. |
- Arking, D. E., et al.
(författare)
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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
- 2014
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Ingår i: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 46:8, s. 826-836
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Tidskriftsartikel (refereegranskat)abstract
- The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac death (SCD) and could indicate the presence of the potentially lethal mendelian long-QT syndrome (LQTS). Using a genome-wide association and replication study in up to 100,000 individuals, we identified 35 common variant loci associated with QT interval that collectively explain ∼ 8-10% of QT-interval variation and highlight the importance of calcium regulation in myocardial repolarization. Rare variant analysis of 6 new QT interval-associated loci in 298 unrelated probands with LQTS identified coding variants not found in controls but of uncertain causality and therefore requiring validation. Several newly identified loci encode proteins that physically interact with other recognized repolarization proteins. Our integration of common variant association, expression and orthogonal protein-protein interaction screens provides new insights into cardiac electrophysiology and identifies new candidate genes for ventricular arrhythmias, LQTS and SCD. © 2014 Nature America, Inc.
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| 2. |
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| 3. |
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| 4. |
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| 5. |
- Berndt, Sonja I., et al.
(författare)
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Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia
- 2013
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 45:8, s. 868-U202
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Tidskriftsartikel (refereegranskat)abstract
- Genome-wide association studies (GWAS) have previously identified 13 loci associated with risk of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL). To identify additional CLL susceptibility loci, we conducted the largest meta-analysis for CLL thus far, including four GWAS with a total of 3,100 individuals with CLL (cases) and 7,667 controls. In the meta-analysis, we identified ten independent associated SNPs in nine new loci at 10q23.31 (ACTA2 or FAS (ACTA2/FAS), P = 1.22 x 10(-14)), 18q21.33 (BCL2, P = 7.76 x 10(-11)), 11p15.5 (C11orf21, P = 2.15 x 10(-10)), 4q25 (LEF1, P = 4.24 x 10(-10)), 2q33.1 (CASP10 or CASP8 (CASP10/CASP8), P = 2.50 x 10(-9)), 9p21.3 (CDKN2B-AS1, P = 1.27 x 10(-8)), 18q21.32 (PMAIP1, P = 2.51 x 10(-8)), 15q15.1 (BMF, P = 2.71 x 10(-10)) and 2p22.2 (QPCT, P = 1.68 x 10(-8)), as well as an independent signal at an established locus (2q13, ACOXL, P = 2.08 x 10(-18)). We also found evidence for two additional promising loci below genome-wide significance at 8q22.3 (ODF1, P = 5.40 x 10(-8)) and 5p15.33 (TERT, P = 1.92 x 10(-7)). Although further studies are required, the proximity of several of these loci to genes involved in apoptosis suggests a plausible underlying biological mechanism.
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| 6. |
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| 8. |
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| 9. |
- Fernandez-Rozadilla, C., et al.
(författare)
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A genome-wide association study on copy-number variation identifies a 11q11 loss as a candidate susceptibility variant for colorectal cancer
- 2014
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Ingår i: Human Genetics. - : Springer Science and Business Media LLC. - 1432-1203 .- 0340-6717. ; 133:5, s. 525-534
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Tidskriftsartikel (refereegranskat)abstract
- Colorectal cancer (CRC) is a complex disease, and therefore its development is determined by the combination of both environmental factors and genetic variants. Although genome-wide association studies (GWAS) of SNP variation have conveniently identified 20 genetic variants so far, a significant proportion of the observed heritability is yet to be explained. Common copy-number variants (CNVs) are one of the most important genomic sources of variability, and hence a potential source to explain part of this missing genetic fraction. Therefore, we have performed a GWAS on CNVs to explore the relationship between common structural variation and CRC development. Phase 1 of the GWAS consisted of 881 cases and 667 controls from a Spanish cohort. Copy-number status was validated by quantitative PCR for each of those common CNVs potentially associated with CRC in phase I. Subsequently, SNPs were chosen as proxies for the validated CNVs for phase II replication (1,342 Spanish cases and 1,874 Spanish controls). Four common CNVs were found to be associated with CRC and were further replicated in Phase II. Finally, we found that SNP rs1944682, tagging a 11q11 CNV, was nominally associated with CRC susceptibility (p value = 0.039; OR = 1.122). This locus has been previously related to extreme obesity phenotypes, which could suggest a relationship between body weight and CRC susceptibility.
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| 10. |
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| 11. |
- Carracedo, J. C., et al.
(författare)
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Evolution of ocean-island rifts : The northeast rift zone of Tenerife, Canary Islands
- 2011
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Ingår i: Geological Society of America Bulletin. - 0016-7606 .- 1943-2674. ; 123:3-4, s. 562-584
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Tidskriftsartikel (refereegranskat)abstract
- The northeast rift zone of Tenerife presents a superb opportunity to study the entire cycle of activity of an oceanic rift zone. Field geology, isotopic dating, and magnetic stratigraphy provide a reliable temporal and spatial framework for the evolution of the NE rift zone, which includes a period of very fast growth toward instability (between ca. 1.1 and 0.83 Ma) followed by three successive large landslides: the Micheque and Guimar collapses, which occurred approximately contemporaneously at ca. 830 ka and on either side of the rift, and the La Orotava landslide (between 690 +/- 10 and 566 +/- 13 ka). Our observations suggest that Canarian rift zones show similar patterns of development, which often includes overgrowth, instability, and lateral collapses. Collapses of the rift flanks disrupt established fissural feeding systems, favoring magma ascent and shallow emplacement, which in turn leads to magma differentiation and intermediate to felsic nested eruptions. Rifts and their collapses may therefore act as an important factor in providing architectural and petrological variability to oceanic volcanoes. Conversely, the presence of substantial felsic volcanism in rift settings may indicate the presence of earlier landslide scars, even if concealed by postcollapse volcanism. Comparative analysis of the main rifts in the Canary Islands outlines this general evolutionary pattern: (1) growth of an increasingly high and steep ridge by concentrated basaltic fissure eruptions; (2) flank collapse and catastrophic disruption of the established feeder system of the rift; (3) postcollapse centralized nested volcanism, commonly evolving from initially ultramafic-mafic to terminal felsic compositions (trachytes, phonolites); and (4) progressive decline of nested eruptive activity.
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| 12. |
- Carracedo, J.C., et al.
(författare)
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The Ongoing Volcanic Eruption of El Hierro, Canary Islands
- 2012
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Ingår i: Transaction of the American Geophysical Union, EOS. ; 93, s. 89-90
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- El Hierro, the youngest of the Canary Islands (Spain), is no stranger to hazards associated with volcanic activity or to efforts to minimize the effects of these hazards on local communities. As early as 1793, administrative records of El Hierro indicate that a swarm of earthquakes was felt by locals; fearing a greater volcanic catastrophe, the first evacuation plan of an entire island in the history of the Canaries was prepared. The 1793 eruption was probably submarine with no appreciable consequences other than that the earthquakes were felt [Carracedo, 2008]; over the next roughly 215 years the island was seismically quiet. Yet seismic and volcanic activity are expected on this youngest Canary Island due to its being directly above the presumed location of the Canary Island hot spot, a mantle plume that feeds upwelling magma just under the surface, similar to the Hawaiian Islands. Because of this known geologic activity, the Spanish Instituto Geográfco Nacional (IGN) has managed geophysical monitoring of the island since the beginning of the 1990s.
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| 13. |
- Lappalainen, Tuuli, et al.
(författare)
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Transcriptome and genome sequencing uncovers functional variation in humans
- 2013
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 501:7468, s. 506-511
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Tidskriftsartikel (refereegranskat)abstract
- Genome sequencing projects are discovering millions of genetic variants in humans, and interpretation of their functional effects is essential for understanding the genetic basis of variation in human traits. Here we report sequencing and deep analysis of messenger RNA and microRNA from lymphoblastoid cell lines of 462 individuals from the 1000 Genomes Project-the first uniformly processed high-throughput RNA-sequencing data from multiple human populations with high-quality genome sequences. We discover extremely widespread genetic variation affecting the regulation of most genes, with transcript structure and expression level variation being equally common but genetically largely independent. Our characterization of causal regulatory variation sheds light on the cellular mechanisms of regulatory and loss-of-function variation, and allows us to infer putative causal variants for dozens of disease-associated loci. Altogether, this study provides a deep understanding of the cellular mechanisms of transcriptome variation and of the landscape of functional variants in the human genome.
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| 14. |
- Troll, Valentin, et al.
(författare)
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Floating stones off El Hierro, Canary Islands: xenoliths of pre-island sedimentary origin in the early products of the October 2011 eruption
- 2012
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Ingår i: Solid Earth. - : Copernicus Publications. - 1869-9510 .- 1869-9529. ; 3:1, s. 97-110
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Tidskriftsartikel (refereegranskat)abstract
- A submarine eruption started off the south coast of El Hierro, Canary Islands, on 10 October 2011 and continues at the time of this writing (February 2012). In the first days of the event, peculiar eruption products were found floating on the sea surface, drifting for long distances from the eruption site. These specimens, which have in the meantime been termed "restingolites" (after the close-by village of La Restinga), appeared as black volcanic "bombs" that exhibit cores of white and porous pumice-like material. Since their brief appearance, the nature and origin of these "floating stones" has been vigorously debated among researchers, with important implications for the interpretation of the hazard potential of the ongoing eruption. The "restingolites" have been proposed to be either (i) juvenile high-silica magma (e. g. rhyolite), (ii) remelted magmatic material (trachyte), (iii) altered volcanic rock, or (iv) reheated hyaloclastites or zeolite from the submarine slopes of El Hierro. Here, we provide evidence that supports yet a different conclusion. We have analysed the textures and compositions of representative "restingolites" and compared the results to previous work on similar rocks found in the Canary Islands. Based on their high-silica content, the lack of igneous trace element signatures, the presence of remnant quartz crystals, jasper fragments and carbonate as well as wollastonite (derived from thermal overprint of carbonate) and their relatively high oxygen isotope values, we conclude that "restingolites" are in fact xenoliths from pre-island sedimentary layers that were picked up and heated by the ascending magma, causing them to partially melt and vesiculate. As they are closely resembling pumice in appearance, but are xenolithic in origin, we refer to these rocks as "xeno-pumice". The El Hierro xeno-pumices hence represent messengers from depth that help us to understand the interaction between ascending magma and crustal lithologies beneath the Canary Islands as well as in similar Atlantic islands that rest on sediment-covered ocean crust (e. g. Cape Verdes, Azores). The occurrence of "restingolites" indicates that crustal recycling is a relevant process in ocean islands, too, but does not herald the arrival of potentially explosive high-silica magma in the active plumbing system beneath El Hierro.
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| 15. |
- Ali, Alaa M. G., et al.
(författare)
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Alcohol Consumption and Survival after a Breast Cancer Diagnosis: A Literature-Based Meta-analysis and Collaborative Analysis of Data for 29,239 Cases
- 2014
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Ingår i: Cancer Epidemiology Biomarkers & Prevention. - 1538-7755 .- 1055-9965. ; 23:6, s. 934-945
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Tidskriftsartikel (refereegranskat)abstract
- Background: Evidence for an association of alcohol consumption with prognosis after a diagnosis of breast cancer has been inconsistent. We have reviewed and summarized the published evidence and evaluated the association using individual patient data from multiple case cohorts. Methods: A MEDLINE search to identify studies published up to January 2013 was performed. We combined published estimates of survival time for "moderate drinkers" versus nondrinkers. An analysis of individual participant data using Cox regression was carried out using data from 11 case cohorts. Results: We identified 11 published studies suitable for inclusion in the meta-analysis. Moderate postdiagnosis alcohol consumption was not associated with overall survival [HR, 0.95; 95% confidence interval (CI), 0.85-1.05], but there was some evidence of better survival associated with prediagnosis consumption (HR, 0.80; 95% CI, 0.73-0.88). Individual data on alcohol consumption for 29,239 cases with 4,839 deaths were available from the 11 case cohorts, all of which had data on estrogen receptor (ER) status. For women with ER-positive disease, there was little evidence that pre-or postdiagnosis alcohol consumption is associated with breast cancer-specific mortality, with some evidence of a negative association with all-cause mortality. On the basis of a single study, moderate postdiagnosis alcohol intake was associated with a small reduction in breast cancer-specific mortality for women with ER-negative disease. There was no association with prediagnosis intake for women with ER-negative disease. Conclusion: There was little evidence that pre- or post-diagnosis alcohol consumption is associated with breast cancer-specific mortality for women with ER-positive disease. There was weak evidence that moderate post-diagnosis alcohol intake is associated with a small reduction in breast cancer-specific mortality in ER-negative disease. Impact: Considering the totality of the evidence, moderate postdiagnosis alcohol consumption is unlikely to have a major adverse effect on the survival of women with breast cancer. (C) 2014 AACR.
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| 16. |
- Deegan, Frances M., et al.
(författare)
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Crustal versus source processes recorded in dykes from the Northeast volcanic rift zone of Tenerife, Canary Islands
- 2012
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Ingår i: Chemical Geology. - : Elsevier BV. - 0009-2541 .- 1872-6836. ; 334, s. 324-344
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Tidskriftsartikel (refereegranskat)abstract
- The Miocene–Pliocene Northeast Rift Zone (NERZ) on Tenerife is a well exposed example of a feeder system to a major ocean island volcanic rift. We present elemental and O–Sr–Nd–Pb isotope data for dykes of the NERZ with the aim of unravelling the petrological evolution of the rift and ultimately defining the mantle source contributions. Fractional crystallisation is found to be the principal control on major and trace element variability in the dykes. Differing degrees of low temperature alteration and assimilation of hydrothermally altered island edifice and pre-island siliciclastic sediment elevated the δ18O and the 87Sr/86Sr ratio of many of the dykes, but had little to no discernible effect on Nd and Pb isotopes. Once the data are screened for alteration and shallow level contamination, the underlying source variations of the NERZ essentially reflect derivation from a young High-μ (HIMU, where μ = 238U/204Pb)-type mantle component mixed with depleted mid-ocean ridge-type mantle (DMM). The Pb isotope data of the NERZ rocks (206Pb/204Pb and 207Pb/204Pb range from 19.591 to 19.838 and 15.603 to 15.635, respectively) support a model of initiation and growth of the rift from the Central Shield volcano (Roque del Conde), consistent with latest geochronology results. The similar isotope signature of the NERZ to both the Miocene Central Shield and the Pliocene Las Cañadas central volcano suggests that the central part of Tenerife Island was supplied from a mantle source that remained of similar composition through the Miocene to the Pliocene. This can be explained by the presence of a discrete column of young HIMU-like plume material, ≤ 100 km in vertical extent, occupying the melting zone beneath central Tenerife throughout this period. The most recent central magmatism on Tenerife appears to reflect greater entrainment of DMM material, perhaps due to waning of the HIMU-like “blob” with time.
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| 17. |
- Delcamp, A., et al.
(författare)
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Dykes and structures of the NE rift of Tenerife, Canary Islands : a record of stabilisation and destabilisation of ocean island rift zones
- 2012
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Ingår i: Bulletin of Volcanology. - : Springer. - 0258-8900 .- 1432-0819. ; 74:5, s. 963-980
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Tidskriftsartikel (refereegranskat)abstract
- Many oceanic island rift zones are associated with lateral sector collapses, and several models have been proposed to explain this link. The North–East Rift Zone (NERZ) of Tenerife Island, Spain offers an opportunity to explore this relationship, as three successive collapses are located on both sides of the rift. We have carried out a systematic and detailed mapping campaign on the rift zone, including analysis of about 400 dykes. We recorded dyke morphology, thickness, composition, internal textural features and orientation to provide a catalogue of the characteristics of rift zone dykes. Dykes were intruded along the rift, but also radiate from several nodes along the rift and form en échelon sets along the walls of collapse scars. A striking characteristic of the dykes along the collapse scars is that they dip away from rift or embayment axes and are oblique to the collapse walls. This dyke pattern is consistent with the lateral spreading of the sectors long before the collapse events. The slump sides would create the necessary strike-slip movement to promote en échelon dyke patterns. The spreading flank would probably involve a basal decollement. Lateral flank spreading could have been generated by the intense intrusive activity along the rift but sectorial spreading in turn focused intrusive activity and allowed the development of deep intra-volcanic intrusive complexes. With continued magma supply, spreading caused temporary stabilisation of the rift by reducing slopes and relaxing stress. However, as magmatic intrusion persisted, a critical point was reached, beyond which further intrusion led to large-scale flank failure and sector collapse. During the early stages of growth, the rift could have been influenced by regional stress/strain fields and by pre-existing oceanic structures, but its later and mature development probably depended largely on the local volcanic and magmatic stress/strain fields that are effectively controlled by the rift zone growth, the intrusive complex development, the flank creep, the speed of flank deformation and the associated changes in topography. Using different approaches, a similar rift evolution has been proposed in volcanic oceanic islands elsewhere, showing that this model likely reflects a general and widespread process. This study, however, shows that the idea that dykes orient simply parallel to the rift or to the collapse scar walls is too simple; instead, a dynamic interplay between external factors (e.g. collapse, erosion) and internal forces (e.g. intrusions) is envisaged. This model thus provides a geological framework to understand the evolution of the NERZ and may help to predict developments in similar oceanic volcanoes elsewhere.
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| 18. |
- Delcamp, A., et al.
(författare)
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Vertical axis rotation of the upper portions of the north-east rift of Tenerife Island inferred from paleomagnetic data
- 2010
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Ingår i: Tectonophysics. - : Elsevier BV. - 0040-1951 .- 1879-3266. ; 492:1-4, s. 40-59
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Tidskriftsartikel (refereegranskat)abstract
- Paleomagnetic sampling sites were established in 82 dykes along an 8 km long section of the north-east rift-zone (NERZ) of Tenerife, Canary Islands, Spain. Of the 70 interpretable sites, 16 are of normal polarity and 54 of reversed polarity. Four normal polarity sites and fifteen reverse polarity sites were excluded from the grand mean calculation for statistical reasons. After inverting the reverse polarity sites through the origin, the in-situ grand mean yields a declination (D) = 023.8 degrees, an inclination (I) = 42.3 degrees, alpha(95) = 3.2 degrees, kappa = 39.0, N = 51 that is discordant to the expected late Miocene to Pleistocene field direction (D = 357.6 degrees, I = 38.8 degrees, alpha(95) = 4.7 degrees). This discordance can be explained as either a 26 degrees clockwise vertical axis rotation or a 28 degrees WNW-side-down-tilt about an average 009 degrees horizontal tilt axis. The sampled section is composed of numerous semi-vertical dykes cutting mainly lava flow units that are sub-horizontal and cross-cut by steeply dipping faults (70 degrees-90 degrees). Field evidence is therefore more compatible with a vertical-axis rotation rather than a horizontal axis tilt of the drilled units. We argue that this clockwise vertical-axis rotation is likely related to strike-slip movements that occurred along the edges of the collapse scars and accommodate the emplacement and growth of the underlying intrusive core and associated dykes. Six new Ar-40/Ar-39 age determinations constrain the main interval of dyke emplacement within the NERZ between 0.99 Ma and 0.56 Ma. The intrusive activity in the sampled section of the rift appears to have been almost continuous, with several intrusion pulses that are probably related to flank destabilisation event(s) during the mid Pleistocene. Our study thus demonstrates a long-lived, multi-faceted history that shaped the NERZ.
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| 19. |
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| 20. |
- Perez-Torrado, F. J., et al.
(författare)
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La erupción submarina de La Restinga en la islade El Hierro, Canarias : Octubre 2011-Marzo 2012
- 2012
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Ingår i: Estudios Geológicos. - : Editorial CSIC. - 0367-0449 .- 1988-3250. ; 68:1, s. 5-27
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Tidskriftsartikel (refereegranskat)abstract
- The first signs of renewed volcanic activity at El Hierro began in July 2011 with the occurrence of abundant, low-magnitude earthquakes. The increasing seismicity culminated on October 10, 2011, with the onset of a submarine eruption about 2 km offshore from La Restinga, the southernmost village on El Hierro. The analysis of seismic and deformation records prior to, and throughout, the eruption allowed the reconstruction of its main phases: 1) ascent of magma and migration of hypocentres from beneath the northern coast (El Golfo) towards the south rift zone, close to La Restinga, probably marking the hydraulic fracturing and the opening of the eruptive conduit; and 2) onset and development of a volcanic eruption indicated by sustained and prolonged harmonic tremor whose intensity varied with time. The features monitored during the eruption include location, depth and morphological evolution of the eruptive source and emission of floating volcanic bombs. These bombs initially showed white, vesiculated cores (originated by partial melting of underlying pre-volcanic sediments upon which the island of El Hierro was constructed) and black basanite rims, and later exclusively hollow basanitic lava balloons. The eruptive products have been matched with a fissural submarine eruption without ever having attained surtseyan explosiveness. The eruption has been active for about five months and ended in March 2012, thus becoming the second longest reported historical eruption in the Canary Islands after the Timanfaya eruption in Lanzarote (1730-1736). This eruption provided the first opportunity in 40 years to manage a volcanic crisis in the Canary Islands and to assess the interpretations and decisions taken, thereby gaining experience for improved management of future volcanic activity. Seismicity and deformation during the eruption were recorded and analysed by the Instituto Geografico Nacional (IGN). Unfortunately, a lack of systematic sampling of erupted pyroclasts and lavas, as well as the sporadic monitoring of the depth and growth of the submarine vent by deployment of a research vessel, hampered a comprehensive assessment of hazards posed during volcanic activity. Thus, available scientific data and advice were not as high quality as they could have been, thereby limiting the authorities in making the proper decisions at crucial points during the crisis. The response in 2011-12 to the El Hierro eruption has demonstrated that adequate infrastructure and technical means exist in the Canary Islands for the early detection of potential eruptive hazards. However, it also has taught us that having detailed emergency management plans may be of limited value without an accompanying continuous, well-integrated scientific monitoring effort (open to national and international collaboration) during all stages of an eruption.
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| 21. |
- Perez-Torrado, F.J., et al.
(författare)
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The submarine erupton of La Restinga (El Hierro, Canary Islands): : October 2011 - March 2012
- 2012
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Ingår i: Estudios Geológicos. - : Editorial CSIC. - 1988-3250 .- 0367-0449. ; 68:1
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Tidskriftsartikel (refereegranskat)abstract
- Los primeros indicios de una posible erupción volcánica en El Hierro se percibieron a partir de julio de 2011 en forma de sismos de baja intensidad pero anormalmente numerosos. La intensificación de la sismicidad culminó con el inicio de la erupción submarina el 10 de octubre de 2011 a unos 2 km al sur de La Restinga. La sismicidad y deformación del terreno que precedieron y acompañaron a esta erupción han permitido reconstruir las principales fases de actividad volcánica: 1) generación y ascenso del magma con migración de los hipocentros sísmicos desde el norte, en el Golfo, hasta el rift sur, en La Restinga, marcando la apertura hidráulica del conducto magmático; y 2) inicio y continuidad de la erupción volcánica evidenciada por un tremor armónico continuo de intensidad variable en el tiempo. Las características observadas a lo largo de la erupción, principalmente localización, profundidad y evolución morfológica del foco emisor, así como emisión de materiales volcánicos flotantes, inicialmente con un núcleo blanco poroso (procedentes de la fusión parcial de sedimentos de la capa superior de la corteza oceánica anteriores a la construcción del edificio insular de El Hierro) envuelto por una corteza basanítica y después huecas (lava balloons), se han correspondido con una erupción submarina fisural profunda sin que nunca hayan intervenido mecanismos más explosivos tipo surtseyano. La erupción se mantuvo activa durante unos cinco meses, dándose por finalizada en marzo del 2012, convirtiéndose de este modo en la segunda erupción histórica más longeva de Canarias después de la de Timanfaya (1730-36) en Lanzarote. Esta erupción ha supuesto la primera oportunidad en 40 años de gestionar una crisis volcánica en Canarias y de analizar las observaciones e interpretaciones y las decisiones adoptadas, con objeto de mejorar la gestión de futuras crisis volcánicas. El Instituto Geográfico Nacional (IGN) se encargó de adquirir y analizar la información sísmica y de deformación durante todo el proceso. Sin embargo, no se dispuso inicialmente de un barco oceanográfico que realizara estudios sistemáticos de la profundidad y progresión de la erupción, así como de toma de muestras de los materiales emitidos (piroclastos y lavas), elementos claves para la determinación de la peligrosidad eruptiva. Estas deficiencias en el seguimiento científico del proceso eruptivo dificultaron en algunos momentos la toma de decisiones de protección civil. El análisis de la crisis ha puesto de manifiesto que, aunque se disponga de una infraestructura técnica adecuada para la detección temprana de crisis eruptivas en el archipiélago, de poco valen las medidas administrativas planificadas sin un seguimiento científico continuo e integrador del proceso eruptivo, abierto a la colaboración científica nacional e internacional.
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| 22. |
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| 23. |
- Wiesmaier, S., et al.
(författare)
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Bimodality of lavas in the teide-pico viejo succession in tenerife-the role of crustal melting in the origin of recent phonolites
- 2012
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Ingår i: Journal of Petrology. - : Oxford University Press (OUP). - 0022-3530 .- 1460-2415. ; 53:12, s. 2465-2495
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Tidskriftsartikel (refereegranskat)abstract
- In Tenerife, lavas of the recent Teide-Pico Viejo central complex show a marked bimodality in composition from initially mafic lavas (200-30 ka) to highly differentiated phonolites (30-0 ka). After this abrupt change, the bimodality of the lavas continued to manifest itself between the now felsic Teide-Pico Viejo central complex and the adjacent, but exclusively mafic, rift zones. Whole-rock trace element fingerprinting distinguishes three compositional groups (mafic, transitional, felsic). Groundmass Sr-Nd-Pb-O and feldspar δ. 18O data demonstrate open-system behaviour for the petrogenesis of the Teide-Pico Viejo felsic lavas by high. 87Sr/. 86Sr ratios of up to 0·7049, uniform. 206Pb/. 204Pb (19·75-19·78), variable. 207Pb/. 204Pb (15·53-15·62) and heterogeneous δ. 18O values (5·43-6·80‰). However, ocean sediment contamination can be excluded because of the low. 206Pb/. 204Pb ratios of North Atlantic sediments. Isotope mixing hyperbolae reproduce the entire Teide-Pico Viejo succession and require an assimilant of predominantly felsic composition. Unsystematic and heterogeneous variation of δ. 18O in fresh and unaltered feldspars across the Teide-Pico Viejo succession indicates magmatic addition of diverse δ. 18O assimilants, altered near surface at high and low temperatures. The best fit for these requirements is provided by nepheline syenite that occurs as fresh or altered lithic blocks in voluminous pre-Teide ignimbrite deposits and is similarly heterogeneous in oxygen isotope composition. Nepheline syenite blocks are considered to represent deep remnants of associated earlier eruptions and were thus available for assimilation at depth. Rare earth element modelling indicates that nepheline syenite needs to be melted in bulk to form a suitable end-member composition. Using this assimilant, energy-constrained assimilation fractional crystallization (EC-AFC) modelling reproduces the bulk of the succession, which leads us to suggest that Teide-Pico Viejo petrogenesis is governed by assimilation and fractional crystallization. Both mixing hyperbolae and EC-AFC models indicate that assimilation is more pronounced for the more felsic lavas. The maximum assimilation is evident in the most strongly differentiated (and the most radiogenic in Sr) lava and computes to >97·8% of the assimilant. This most evolved eruption probably represents nepheline syenite bulk melts that formed spatially decoupled from juvenile material. This study therefore recognizes a wider variability of magmatic differentiation processes at Teide-Pico Viejo than previously thought.
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| 24. |
- Wiesmaier, Sebastian, et al.
(författare)
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Magmatic Differentiation in the Teide–Pico Viejo Succession : Isotope Analysis as a Key to Deciphering the Origin of Phonolite Magma
- 2013
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Ingår i: Teide Volcano. - Berlin, Heidelberg : Springer Berlin/Heidelberg. - 9783642258923 - 9783642258930 ; , s. 173-190
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Bokkapitel (refereegranskat)abstract
- In Tenerife, lavas of the recent Teide–Pico Viejo central complex show a marked bimodality in composition from initially mafic lava (200–30 ka) to highly differentiated phonolite (30–0 ka). Groundmass Sr–Nd–Pb–O and feldspar 18O data demonstrate open system behaviour for the petrogenesis of Teide–Pico Viejo felsic lavas, but contamination by ocean sediment can be excluded due to the low 206Pb/204Pb ratios of North Atlantic sediment. Isotope mixing hyperbolae require an assimilant of predominantly felsic composition for the Teide–Pico Viejo succession. Unsystematic and heterogeneous variation of 18O in fresh and unaltered feldspars across the Teide–Pico Viejo succession indicates magmatic addition of diverse 18O assimilants, best matched by nepheline syenites that occur as fresh and altered lithic blocks in voluminous pre-Teide ignimbrite deposits. Rare earth element modelling indicates that nepheline syenite needs to be melted in bulk to form a suitable end-member composition. Energy-Constrained Assimilation Fractional Crystallisation (EC-AFC) modelling reproduces the bulk of the succession, which implies that the petrogenesis of Teide–Pico Viejo lavas is governed by the coupled assimilation of nepheline syenite during fractional crystallisation. The most differentiated (and most radiogenic) lava computes to >97.8 % assimilant, likely represented by a nepheline syenite bulk melt that formed by underplating with juvenile mafic material. These recent research developments therefore recognise a wider variability of magmatic differentiation processes at Teide–Pico Viejo than previously considered.
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| 25. |
- Wiesmaier, Sebastian, et al.
(författare)
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Open-system processes in the differentiation of mafic magma in the Teide-Pico Viejo succession, Tenerife
- 2013
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Ingår i: Journal of the Geological Society. - : Geological Society of London. - 0016-7649 .- 2041-479X. ; 170:3, s. 557-570
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Tidskriftsartikel (refereegranskat)abstract
- Oceanic island basalts are commonly thought to differentiate by fractional crystallization, yet closed-system fractionation models have so far failed to reproduce major and trace element variations observed in mafic lavas from the Teide-Pico Viejo stratovolcano complex on Tenerife. Here, new high-precision plagioclase trace element data are fed into such a fractionation model. The results confirm that fractionation of phenocrysts found in the lavas does not reproduce trace element variations, in particular enrichment of Sr and Zr observed in the Teide-Pico Viejo mafic suite. This enrichment of Sr and Zr is tested by an energy-constrained recharge, assimilation and fractional crystallization (EC-RAFC) model at high T and low Lambda T intervals, consistent with previously determined magma storage beneath Tenerife at sub-Moho depths. Published mineral-melt equilibrium relations using the plagioclase anorthite content (0.4 < X-An < 0.8) constrain the temperature during differentiation. Gabbroic xenoliths found in Tenerife lavas are assumed as contaminant. Enrichment of Sr and Zr in the Teide mafic suite is reproduced by this combined assimilation and fractional crystallization model, as assimilation causes higher degrees of enrichment in incompatible trace elements than is possible by crystal fractionation alone. Recycling of plutonic roots may thus have significantly enriched trace elements in the primitive lavas of the Teide-Pico Viejo succession.
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