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- Franceschini, N., et al.
(author)
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GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
- 2018
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In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 9:1
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Journal article (peer-reviewed)abstract
- Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart disease (CHD). Here, we undertake meta-analyses of genome-wide association studies (GWAS) in 71,128 individuals for cIMT, and 48,434 individuals for carotid plaque traits. We identify eight novel susceptibility loci for cIMT, one independent association at the previously-identified PINX1 locus, and one novel locus for carotid plaque. Colocalization analysis with nearby vascular expression quantitative loci (cis-eQTLs) derived from arterial wall and metabolic tissues obtained from patients with CHD identifies candidate genes at two potentially additional loci, ADAMTS9 and LOXL4. LD score regression reveals significant genetic correlations between cIMT and plaque traits, and both cIMT and plaque with CHD, any stroke subtype and ischemic stroke. Our study provides insights into genes and tissue-specific regulatory mechanisms linking atherosclerosis both to its functional genomic origins and its clinical consequences in humans. © 2018, The Author(s).
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- Blanton, Michael R., et al.
(author)
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Sloan Digital Sky Survey IV : Mapping the Milky Way, Nearby Galaxies, and the Distant Universe
- 2017
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In: Astronomical Journal. - : IOP Publishing Ltd. - 0004-6256 .- 1538-3881. ; 154:1
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Journal article (peer-reviewed)abstract
- We describe the Sloan Digital Sky Survey IV (SDSS-IV), a project encompassing three major spectroscopic programs. The Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2) is observing hundreds of thousands of Milky Way stars at high resolution and. high signal-to-noise ratios in the near-infrared. The Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey is obtaining spatially resolved spectroscopy for thousands of nearby galaxies (median z similar to 0.03). The extended Baryon Oscillation Spectroscopic Survey (eBOSS) is mapping the galaxy, quasar, and neutral gas distributions between z similar to 0.6 and 3.5 to constrain cosmology using baryon acoustic oscillations, redshift space distortions, and the shape of the power spectrum. Within eBOSS, we are conducting two major subprograms: the SPectroscopic IDentification of eROSITA Sources (SPIDERS), investigating X-ray AGNs. and galaxies in X-ray clusters, and the Time Domain Spectroscopic Survey (TDSS), obtaining spectra of variable sources. All programs use the 2.5 m Sloan Foundation Telescope at the. Apache Point Observatory; observations there began in Summer 2014. APOGEE-2 also operates a second near-infrared spectrograph at the 2.5 m du Pont Telescope at Las Campanas Observatory, with observations beginning in early 2017. Observations at both facilities are scheduled to continue through 2020. In keeping with previous SDSS policy, SDSS-IV provides regularly scheduled public data releases; the first one, Data Release 13, was made available in 2016 July.
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- Abolfathi, Bela, et al.
(author)
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The Fourteenth Data Release of the Sloan Digital Sky Survey : First Spectroscopic Data from the Extended Baryon Oscillation Spectroscopic Survey and from the Second Phase of the Apache Point Observatory Galactic Evolution Experiment
- 2018
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In: Astrophysical Journal Supplement Series. - : IOP Publishing Ltd. - 0067-0049 .- 1538-4365. ; 235:2
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Journal article (peer-reviewed)abstract
- The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since 2014 July. This paper describes the second data release from this phase, and the 14th from SDSS overall (making this Data Release Fourteen or DR14). This release makes the data taken by SDSS-IV in its first two years of operation (2014-2016 July) public. Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey; the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data-driven machine-learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from the SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS web site (www.sdss.org) has been updated for this release and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020 and will be followed by SDSS-V.
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- Spinoglio, L., et al.
(author)
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- 2017
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In: Publications Astronomical Society of Australia. - : Cambridge University Press (CUP). - 1323-3580 .- 1448-6083. ; 34
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Journal article (peer-reviewed)abstract
- IR spectroscopy in the range 12-230 mu m with the SPace IR telescope for Cosmology and Astrophysics (SPICA) will reveal the physical processes governing the formation and evolution of galaxies and black holes through cosmic time, bridging the gap between the James Webb Space Telescope and the upcoming Extremely Large Telescopes at shorter wavelengths and the Atacama Large Millimeter Array at longer wavelengths. The SPICA, with its 2.5-m telescope actively cooled to below 8 K, will obtain the first spectroscopic determination, in the mid-IR rest-frame, of both the star-formation rate and black hole accretion rate histories of galaxies, reaching lookback times of 12 Gyr, for large statistically significant samples. Densities, temperatures, radiation fields, and gas-phase metallicities will be measured in dust-obscured galaxies and active galactic nuclei, sampling a large range in mass and luminosity, from faint local dwarf galaxies to luminous quasars in the distant Universe. Active galactic nuclei and starburst feedback and feeding mechanisms in distant galaxies will be uncovered through detailed measurements of molecular and atomic line profiles. The SPICA's large-area deep spectrophotometric surveys will provide mid-IR spectra and continuum fluxes for unbiased samples of tens of thousands of galaxies, out to redshifts of z similar to 6.
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- Aguado, D. S., et al.
(author)
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The Fifteenth Data Release of the Sloan Digital Sky Surveys : First Release of MaNGA-derived Quantities, Data Visualization Tools, and Stellar Library
- 2019
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In: Astrophysical Journal Supplement Series. - : Institute of Physics Publishing (IOPP). - 0067-0049 .- 1538-4365. ; 240:2
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Journal article (peer-reviewed)abstract
- Twenty years have passed since first light for the Sloan Digital Sky Survey (SDSS). Here, we release data taken by the fourth phase of SDSS (SDSS-IV) across its first three years of operation (2014 July-2017 July). This is the third data release for SDSS-IV, and the 15th from SDSS (Data Release Fifteen; DR15). New data come from MaNGA-we release 4824 data cubes, as well as the first stellar spectra in the MaNGA Stellar Library (MaStar), the first set of survey-supported analysis products (e.g., stellar and gas kinematics, emission-line and other maps) from the MaNGA Data Analysis Pipeline, and a new data visualization and access tool we call "Marvin." The next data release, DR16, will include new data from both APOGEE-2 and eBOSS; those surveys release no new data here, but we document updates and corrections to their data processing pipelines. The release is cumulative; it also includes the most recent reductions and calibrations of all data taken by SDSS since first light. In this paper, we describe the location and format of the data and tools and cite technical references describing how it was obtained and processed. The SDSS website (www.sdss.org) has also been updated, providing links to data downloads, tutorials, and examples of data use. Although SDSS-IV will continue to collect astronomical data until 2020, and will be followed by SDSS-V (2020-2025), we end this paper by describing plans to ensure the sustainability of the SDSS data archive for many years beyond the collection of data.
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- Schultheis, M., et al.
(author)
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Baade's window and APOGEE Metallicities, ages, and chemical abundances
- 2017
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In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 600
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Journal article (peer-reviewed)abstract
- Context. Baade's window (BW) is one of the most observed Galactic bulge fields in terms of chemical abundances. Owing to its low and homogeneous interstellar absorption it is considered the perfect calibration field for Galactic bulge studies. Aims. In the era of large spectroscopic surveys, calibration fields such as BW are necessary for cross calibrating the stellar parameters and individual abundances of the APOGEE survey. Methods. We use the APOGEE BW stars to derive the metallicity distribution function (MDF) and individual abundances for alpha- and iron-peak elements of the APOGEE ASPCAP pipeline (DR13), as well as the age distribution for stars in BW. Results. We determine the MDF of APOGEE stars in BW and find a remarkable agreement with that of the Gaia-ESO survey (GES). Both exhibit a clear bimodal distribution. We also find that the Mg-metallicity planes of the two surveys agree well, except for the metal-rich part ([Fe/H] > 0.1), where APOGEE finds systematically higher Mg abundances with respect to the GES. The ages based on the [C/N] ratio reveal a bimodal age distribution, with a major old population at similar to 10 Gyr, with a decreasing tail towards younger stars. A comparison of stellar parameters determined by APOGEE and those determined by other sources reveals detectable systematic offsets, in particular for spectroscopic surface gravity estimates. In general, we find a good agreement between individual abundances of O,Na, Mg, Al, Si, K, Ca, Cr, Mn, Co, and Ni from APOGEE with that of literature values. Conclusions. We have shown that in general APOGEE data show a good agreement in terms of MDF and individual chemical abundances with respect to literature works. Using the [C/N] ratio we found a significant fraction of young stars in BW.
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| 22. |
- Ranalli, P., et al.
(author)
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The 2-10 keV unabsorbed luminosity function of AGN from the LSS, CDFS, and COSMOS surveys
- 2016
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In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 590
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Journal article (peer-reviewed)abstract
- The XMM-Large scale structure (XMM-LSS), XMM-Cosmological evolution survey (XMM-COSMOS), and XMM-Chandra deep field south (XMM-CDFS) surveys are complementary in terms of sky coverage and depth. Together, they form a clean sample with the least possible variance in instrument effective areas and point spread function. Therefore this is one of the best samples available to determine the 2-10 keV luminosity function of active galactic nuclei (AGN) and their evolution. The samples and the relevant corrections for incompleteness are described. A total of 2887 AGN is used to build the LF in the luminosity interval 1042-1046 erg s-1 and in the redshift interval 0.001-4. A new method to correct for absorption by considering the probability distribution for the column density conditioned on the hardness ratio is presented. The binned luminosity function and its evolution is determined with a variant of the Page-Carrera method, which is improved to include corrections for absorption and to account for the full probability distribution of photometric redshifts. Parametric models, namely a double power law with luminosity and density evolution (LADE) or luminosity-dependent density evolution (LDDE), are explored using Bayesian inference. We introduce the Watanabe-Akaike information criterion (WAIC) to compare the models and estimate their predictive power. Our data are best described by the LADE model, as hinted by the WAIC indicator. We also explore the recently proposed 15-parameter extended LDDE model and find that this extension is not supported by our data. The strength of our method is that it provides unabsorbed, non-parametric estimates, credible intervals for luminosity function parameters, and a model choice based on predictive power for future data.
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| 23. |
- Soubiran, C., et al.
(author)
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Open cluster kinematics with Gaia DR2
- 2018
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In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 619
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Journal article (peer-reviewed)abstract
- Context: Open clusters are very good tracers of the evolution of the Galactic disc. Thanks to Gaia, their kinematics can be investigated with an unprecedented precision and accuracy.Aims: The distribution of open clusters in the 6D phase space is revisited with Gaia DR2.Methods: The weighted mean radial velocity of open clusters was determined, using the most probable members available from a previous astrometric investigation that also provided mean parallaxes and proper motions. Those parameters, all derived from Gaia DR2 only, were combined to provide the 6D phase-space information of 861 clusters. The velocity distribution of nearby clusters was investigated, as well as the spatial and velocity distributions of the whole sample as a function of age. A high-quality subsample was used to investigate some possible pairs and groups of clusters sharing the same Galactic position and velocity.Results: For the high-quality sample of 406 clusters, the median uncertainty of the weighted mean radial velocity is 0.5 km s(-1). The accuracy, assessed by comparison to ground-based high-resolution spectroscopy, is better than 1 km s(-1). Open clusters nicely follow the velocity distribution of field stars in the close solar neighbourhood as previously revealed by Gaia DR2. As expected, the vertical distribution of young clusters is very flat, but the novelty is the high precision to which this can be seen. The dispersion of vertical velocities of young clusters is at the level of 5 km s(-1). Clusters older than 1 Gyr span distances to the Galactic plane of up to 1 kpc with a vertical velocity dispersion of 14 km s(-1) , typical of the thin disc. Five pairs of clusters and one group with five members might be physically related. Other binary candidates that have been identified previously are found to be chance alignments.
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| 24. |
- Zamora, O., et al.
(author)
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New H-Band Stellar Spectral Libraries for the SdSS-III/Apogee Survey
- 2015
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In: Astronomical Journal. - : American Astronomical Society. - 0004-6256 .- 1538-3881. ; 149:6
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Journal article (peer-reviewed)abstract
- The Sloan Digital Sky Survey-III (SDSS-III) Apache Point Observatory Galactic Evolution Experiment (APOGEE) has obtained high-resolution (R similar to 22,500), high signal-to-noise ratio (>100) spectra in the H-band (similar to 1.5-1.7 mu m) for about 146,000 stars in the Milky Way galaxy. We have computed spectral libraries with effective temperature (T-eff) ranging from 3500 to 8000 K for the automated chemical analysis of the survey data. The libraries, used to derive stellar parameters and abundances from the APOGEE spectra in the SDSS-III data release 12 (DR12), are based on ATLAS9 model atmospheres and the ASS epsilon T spectral synthesis code. We present a second set of libraries based on MARCS model atmospheres and the spectral synthesis code Turbospectrum. The ATLAS9/ASS epsilon T (T-eff = 3500-8000 K) and MARCS/Turbospectrum (T-eff = 3500-5500 K) grids cover a wide range of metallicity (-2.5 <= [M/H] <= + 0.5 dex), surface gravity (0 <= log g <= 5 dex), microturbulence (0.5 <= xi <= 8 km s(-1)), carbon (-1 <= [C/M] <= + 1 dex), nitrogen (-1 <= [N/M] <= + 1 dex), and alpha-element (-1 <= [alpha/M] <= + 1 dex) variations, having thus seven dimensions. We compare the ATLAS9/ASS.T and MARCS/Turbospectrum libraries and apply both of them to the analysis of the observed H-band spectra of the Sun and the K2 giant Arcturus, as well as to a selected sample of well-known giant stars observed at very high resolution. The new APOGEE libraries are publicly available and can be employed for chemical studies in the H-band using other high-resolution spectrographs.
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- Falocco, Serena, et al.
(author)
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The XMM deep survey in the CDF-S X. X-ray variability of bright sources
- 2017
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In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 608
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Journal article (peer-reviewed)abstract
- Aims. We aim to study the variability properties of bright hard X-ray selected active galactic nuclei (AGN) in the redshift range between 0.3 and 1.6 detected in the Chandra Deep Field South (XMM-CDFS) by a long (similar to 3 Ms) XMM observation.& para;& para;Methods. Taking advantage of the good count statistics in the XMM CDFS, we search for flux and spectral variability using the hardness ratio (HR) techniques. We also investigate the spectral variability of different spectral components (photon index of the power law, column density of the local absorber, and reflection intensity). The spectra were merged in six epochs (defined as adjacent observations) and in high and low flux states to understand whether the flux transitions are accompanied by spectral changes.& para;& para;Results. The flux variability is significant in all the sources investigated. The HRs in general are not as variable as the fluxes, in line with previous results on deep fields. Only one source displays a variable HR, anti-correlated with the flux (source 337). The spectral analysis in the available epochs confirms the steeper when brighter trend consistent with Comptonisation models only in this source at 99% confidence level. Finding this trend in one out of seven unabsorbed sources is consistent, within the statistical limits, with the 15% of unabsorbed AGN in previous deep surveys. No significant variability in the column densities, nor in the Compton reflection component, has been detected across the epochs considered. The high and low states display in general different normalisations but consistent spectral properties.& para;& para;Conclusions. X-ray flux fluctuations are ubiquitous in AGN, though in some cases the data quality does not allow for their detection. In general, the significant flux variations are not associated with spectral variability: photon index and column densities are not significantly variable in nine out of the ten AGN over long timescales (from three to six and a half years). Photon index variability is found only in one source (which is steeper when brighter) out of seven unabsorbed AGN. The percentage of spectrally variable objects is consistent, within the limited statistics of sources studied here, with previous deep samples.
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