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3.
  • Bixby, H., et al. (author)
  • Rising rural body-mass index is the main driver of the global obesity epidemic in adults
  • 2019
  • In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 569:7755, s. 260-4
  • Journal article (peer-reviewed)abstract
    • Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.
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  • 2017
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:2
  • Journal article (peer-reviewed)
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5.
  • Aaltonen, T., et al. (author)
  • Tevatron Run II combination of the effective leptonic electroweak mixing angle
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 97:11
  • Journal article (peer-reviewed)abstract
    • Drell-Yan lepton pairs produced in the process p (p) over bar -> l(+)l(-) + X through an intermediate gamma*/Z boson have an asymmetry in their angular distribution related to the spontaneous symmetry breaking of the electroweak force and the associated mixing of its neutral gauge bosons. The CDF and D0 experiments have measured the effective-leptonic electroweak mixing parameter sin(2) theta(lept)(eff) using electron and muon pairs selected from the full Tevatron proton-antiproton data sets collected in 2001-2011, corresponding to 9-10 fb(-1) of integrated luminosity. The combination of these measurements yields the most precise result from hadron colliders, sin(2)theta(lept)(eff) = 0.23148 +/- 0.00033. This result is consistent with, and approaches in precision, the best measurements from electron-positron colliders. The standard model inference of the on-shell electroweak mixing parameter sin(2) theta(W), or equivalently the W-boson mass M-W, using the ZFITTER software package yields sin(2) theta(W) = 0.22324 +/- 0.00033 or equivalently, M-W = 80.367 +/- 0.017 GeV/c(2).
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6.
  • Aaltonen, T., et al. (author)
  • Combined Forward-Backward Asymmetry Measurements in Top-Antitop Quark Production at the Tevatron
  • 2018
  • In: Physical Review Letters. - : AMER PHYSICAL SOC. - 0031-9007 .- 1079-7114. ; 120:4
  • Journal article (peer-reviewed)abstract
    • The CDF and D0 experiments at the Fermilab Tevatron have measured the asymmetry between yields of forward- and backward-produced top and antitop quarks based on their rapidity difference and the asymmetry between their decay leptons. These measurements use the full data sets collected in proton-antiproton collisions at a center-of-mass energy of root s = 1.96 TeV. We report the results of combinations of the inclusive asymmetries and their differential dependencies on relevant kinematic quantities. The combined inclusive asymmetry is A(FB)(t (t) over bar) = 0.128 +/- 0.025. The combined inclusive and differential asymmetries are consistent with recent standard model predictions.
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7.
  • Aaltonen, T., et al. (author)
  • Tevatron Combination of Single-Top-Quark Cross Sections and Determination of the Magnitude of the Cabibbo-Kobayashi-Maskawa Matrix Element V-tb
  • 2015
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 115:15
  • Journal article (peer-reviewed)abstract
    • We present the final combination of CDF and D0 measurements of cross sections for single-top-quark production in proton-antiproton collisions at a center-of-mass energy of 1.96 TeV. The data correspond to total integrated luminosities of up to 9.7 fb(-1) per experiment. The t-channel cross section is measured to be sigma(t) = 2.25(-0.31)(+0.29) pb. We also present the combinations of the two-dimensional measurements of the s- vs t-channel cross section. In addition, we give the combination of the s + t channel cross section measurement resulting in sigma(s+t) = 3.30(-0.40)(+0.52) pb, without assuming the standard model value for the ratio sigma(s)/sigma(t). The resulting value of the magnitude of the top-to-bottom quark coupling is vertical bar V-tb vertical bar = 1.02(-0.05)(+0.06), corresponding to vertical bar V-tb vertical bar > 0.92 at the 95% C. L.
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8.
  • Aaltonen, T., et al. (author)
  • Tevatron Constraints on Models of the Higgs Boson with Exotic Spin and Parity Using Decays to Bottom-Antibottom Quark Pairs
  • 2015
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 114:15
  • Journal article (peer-reviewed)abstract
    • Combined constraints from the CDF and D0 Collaborations on models of the Higgs boson with exotic spin J and parity P are presented and compared with results obtained assuming the standard model value J(P) = 0(+). Both collaborations analyzed approximately 10 fb(-1) of proton-antiproton collisions with a center-of-mass energy of 1.96 TeV collected at the Fermilab Tevatron. Two models predicting exotic Higgs bosons with J(P) = 0(-) and J(P) = 2(+) are tested. The kinematic properties of exotic Higgs boson production in association with a vector boson differ from those predicted for the standard model Higgs boson. Upper limits at the 95% credibility level on the production rates of the exotic Higgs bosons, expressed as fractions of the standard model Higgs boson production rate, are set at 0.36 for both the J(P) = 0(-) hypothesis and the J(P) = 2(+) hypothesis. If the production rate times the branching ratio to a bottom-antibottom pair is the same as that predicted for the standard model Higgs boson, then the exotic bosons are excluded with significances of 5.0 standard deviations and 4.9 standard deviations for the J(P) = 0(-) and J(P) = 2(+) hypotheses, respectively.
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10.
  • Ruilope, LM, et al. (author)
  • Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial
  • 2019
  • In: American journal of nephrology. - : S. Karger AG. - 1421-9670 .- 0250-8095. ; 50:5, s. 345-356
  • Journal article (peer-reviewed)abstract
    • <b><i>Background:</i></b> Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. <b><i>Patients and</i></b> <b><i>Methods:</i></b> The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate ≥25 mL/min/1.73 m<sup>2</sup> and albuminuria (urinary albumin-to-creatinine ratio ≥30 to ≤5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level α = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. <b><i>Conclusions:</i></b> FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049.
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17.
  • Abazov, V. M., et al. (author)
  • B-s(0) lifetime measurement in the CP-odd decay channel B-s(0) -> J/Psi f(0)(980)
  • 2016
  • In: PHYSICAL REVIEW D. - 2470-0010. ; 94:1
  • Journal article (peer-reviewed)abstract
    • The lifetime of the B-s(0) meson is measured in the decay channel B-s(0) -> J/Psi pi(+)pi(-) with 880 <= M pi+pi- <= 1080 MeV/c(2), which is mainly a CP-odd state and dominated by the f(0)(980) resonance. In 10.4 fb(-1) of data collected with the D0 detector in Run II of the Tevatron, the lifetime of the B-s(0) meson is measured to be tau(B-s(0)) = 1.70 +/- 0.14(stat) +/- 0.05(syst) ps. Neglecting CP violation in B-s(0)/(B) over bar (0)(s) mixing, the measurement can be translated into the width of the heavy mass eigenstate of the B-s(0), Gamma(H) = 0.59 +/- 0.05(stat) +/- 0.02(syst) ps(-1).
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18.
  • Abazov, V. M., et al. (author)
  • Combination of D0 measurements of the top quark mass
  • 2017
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 95:11
  • Journal article (peer-reviewed)abstract
    • We present a combination of measurements of the top quark mass by the D0 experiment in the lepton + jets and dilepton channels. We use all the data collected in Run I (1992-1996) at root s = 1.8 TeV and Run II (2001-2011) at root s = 1.96 TeV of the Tevatron p (p) over bar collider, corresponding to integrated luminosities of 0.1 fb(-1) and 9.7 fb(-1), respectively. The combined result is: m(t) = 174.95 +/- 0.40(stat)+/- 0.64(syst) GeV = 174.95 +/- 0.75 GeV.
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19.
  • Abazov, V. M., et al. (author)
  • Evidence for a B-s(0)pi(+/-) State
  • 2016
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 117:2
  • Journal article (peer-reviewed)abstract
    • We report evidence for a narrow structure, X(5568), in the decay sequence X(5568) -> B-s(0)pi(+/-), B-s(0) -> J/psi phi, J/psi -> mu(+)mu(-), phi -> K+K-. This is evidence for the first instance of a hadronic state with valence quarks of four different flavors. The mass and natural width of this state are measured to be m = 5567.8 +/- 2.9(stat)(-1.9)(+0.9) (syst) MeV/c(2) and Gamma = 21.9 +/- 6.4(stat)(-2.5)(+5.0) (syst) MeV/c(2). If the decay is X(5568) -> B-s*pi(+/-). B-s(0)gamma pi(+/-) with an unseen gamma, m(X(5568)) will be shifted up by m(B-s*) - m(B-s(0)) similar to 49 MeV/c(2). This measurement is based on 10.4 fb(-1) of p (p) over bar collision data at root s = 1.96 TeV collected by the D0 experiment at the Fermilab Tevatron collider.
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20.
  • Abazov, V. M., et al. (author)
  • Evidence for Simultaneous Production of J/psi and Upsilon Mesons
  • 2016
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 116:8
  • Journal article (peer-reviewed)abstract
    • We report evidence for the simultaneous production of J/psi and Upsilon mesons in 8.1 fb(-1) of data collected at root s = 1.96 TeV by the D0 experiment at the Fermilab p (p) over bar Tevatron Collider. Events with these characteristics are expected to be produced predominantly by gluon-gluon interactions. In this analysis, we extract the effective cross section characterizing the initial parton spatial distribution, sigma(eff) = 2.2 +/- 0.7(stat) +/- 0.9(syst) mb.
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21.
  • Abazov, V. M., et al. (author)
  • Evidence for Z(c)(+/-)(3900) in semi-inclusive decays of b-flavored hadrons
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 98:5
  • Journal article (peer-reviewed)abstract
    • We present evidence for the exotic charged charmoniumlike state Z(c)(+/-)(3900) decaying to J/psi pi(+/-) in semi-inclusive weak decays of b-flavored hadrons. The signal is correlated with a parent J/psi pi(+)pi(-) system in the invariant-mass range 4.2-4.7 GeV that would include the exotic structure Y(4260). The study is based on 10.4 fb(-1) of p (p) over bar collision data collected by the D0 experiment at the Fermilab Tevatron collider.
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22.
  • Abazov, V. M., et al. (author)
  • Inclusive Production of the X(4140) State in p(p)over-bar Collisions at D0
  • 2015
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 115:23
  • Journal article (peer-reviewed)abstract
    • We present a study of the inclusive production of the X(4140) state with the decay to the J/psi phi final state in hadronic collisions. Based on 10.4 fb(-1) of p (p) over bar collision data collected by the D0 experiment at the Fermilab Tevatron collider, we report the first evidence for the prompt production of an X(4140) state and find the fraction of X(4140) events originating from b hadrons to be f(b) = 0.39 +/- 0.07 (stat) +/- 0.10 (syst). The ratio of the nonprompt X(4140) production rate to the B-s(0) yield in the same channel is R = 0.19 +/- 0.05 (stat) +/- 0.07 (syst). The values of the mass M = 4152.5 +/- 1.7 (stat)(-5.4)(+/- 6.2)(syst) MeV and width Gamma = 16.3 +/- 5.6 (stat) +/- 11.4 (syst) MeV are consistent with previous measurements.
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23.
  • Abazov, V. M., et al. (author)
  • Measurement of spin correlation between top and antitop quarks produced in p(p)over-bar collisions at root s=1.96 TeV
  • 2016
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 757, s. 199-206
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the correlation between the spins of t and (t) over bar quarks produced in proton-antiproton collisions at the Tevatron Collider at a center-of-mass energy of 1.96 TeV. We apply a matrix element technique to dilepton and single-lepton+jets final states in data accumulated with the DO detector that correspond to an integrated luminosity of 9.7 fb(-1). The measured value of the correlation coefficient in the off-diagonal basis, O-off = 0.89 +/- 0.22 (stat + syst), is in agreement with the standard model prediction, and represents evidence for a top-antitop quark spin correlation difference from zero at a level of 4.2 standard deviations.
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24.
  • Abazov, V. M., et al. (author)
  • Measurement of the B-s(0) Lifetime in the Flavor-Specific Decay Channel B-s(0)-> D-s(-)mu(+)nu X
  • 2015
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 114:6
  • Journal article (peer-reviewed)abstract
    • We present an updated measurement of the B-s(0) lifetime using the semileptonic decays B-s(0) -> D-s(-)mu(+)nu X, with D-s(-) -> phi pi(-) and phi -> K+K- (and the charge conjugate process). This measurement uses the full Tevatron Run II sample of proton-antiproton collisions at root s = 1.96 TeV, comprising an integrated luminosity of 10.4 fb(-1). We find a flavor-specific lifetime tau(fs)(B-s(0)) = 1.479 +/- 0.010(stat) +/- 0.021(syst) ps. This technique is also used to determine the B-0 lifetime using the analogous B-0 -> D- mu(+)nu X decay with D- -> phi pi(-) and phi -> K+K-, yielding tau(B-0) = 1.534 +/- 0.019(stat) +/- 0.021(syst) ps. Both measurements are consistent with the current world averages, and the B-s(0) lifetime measurement is one of the most precise to date. Taking advantage of the cancellation of systematic uncertainties, we determine the lifetime ratio tau(fs)(B-s(0))/tau(B-0) = 0.964 +/- 0.013(stat) +/- 0.007(syst).
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25.
  • Abazov, V. M., et al. (author)
  • Measurement of the direct CP violating charge asymmetry in B-+/- -> mu(+/-)nu D-mu(0) decays
  • 2017
  • In: Physical Review D. - 2470-0010 .- 2470-0029. ; 95:3
  • Journal article (peer-reviewed)abstract
    • We present the first measurement of the CP violating charge asymmetry in B-+/- -> mu(+/-)nu D-mu(0) decays using the full Run II integrated luminosity of 10.4 fb(-1) in proton-antiproton collisions collected with the D0 detector at the Fermilab Tevatron Collider. We measure a difference in the yield of B- and B+ mesons in these decays by fitting the reconstructed invariant mass distributions. This results in an asymmetry of A(mu D0) = [-0.14 +/- 0.20] %, which is consistent with standard model predictions.
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26.
  • Abazov, V. M., et al. (author)
  • Measurement of the Effective Weak Mixing Angle in p(p)over-bar -> Z/gamma* -> e(+)e(-) Events
  • 2015
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 115:4
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the fundamental parameter of the standard model, the weak mixing angle sin(2)theta(l)(eff) which determines the relative strength of weak and electromagnetic interactions, in p (p) over bar -> Z/gamma* -> e(+)e(-) events at a center of mass energy of 1.96 TeV, using data corresponding to 9.7 fb(-1) of integrated luminosity collected by the D0 detector at the Fermilab Tevatron. The effective weak mixing angle is extracted from the forward-backward charge asymmetry as a function of the invariant mass around the Z boson pole. The measured value of sin(2)theta(l)(eff) = 0.23147 +/- 0.00047 is the most precise measurement from light quark interactions to date, with a precision close to the best LEP and SLD results.
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27.
  • Abazov, V. M., et al. (author)
  • Measurement of the Effective Weak Mixing Angle in p¯p→Z/γ∗→ℓ+ℓ− Events
  • 2018
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 120:24
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the effective weak mixing angle parameter sin(2)theta(l)(eff) in p (p) over bar -> Z/gamma* -> mu(+)mu(-) events at a center-of-mass energy of 1.96 TeV, collected by the D0 detector at the Fermilab Tevatron Collider and corresponding to 8.6 fb(-1) of integrated luminosity. The measured value of sin(2)theta(l)(eff)[mu mu] = 0.23016 +/- 0.00064 is further combined with the result from the D0 measurement in p (p) over bar -> Z/gamma* -> e(+)e(-) events, resulting in sin(2)theta(l)(eff)[comb] = 0.23095 +/- 0.00040. This combined result is the most precise measurement from a single experiment at a hadron collider and is the most precise determination using the coupling of the Z/gamma* to light quarks.
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28.
  • Abazov, V. M., et al. (author)
  • Measurement of the electron charge asymmetry in p(p)over-bar -> W + X -> ev plus X decays in p(p)over-bar collisions at root S=1.96 TeV
  • 2015
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 91:3
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the electron charge asymmetry in p (p) over bar -> W + X -> ev + X events at a center-of-mass energy of 1.96 TeV, using data corresponding to 9.7 fb(-1) of integrated luminosity collected with the D0 detector at the Fermilab Tevatron Collider. The asymmetry is measured as a function of the electron pseudorapidity and is presented in five kinematic bins based on the electron transverse energy and the missing transverse energy in the event. The measured asymmetry is compared with next-to-leading-order predictions in perturbative quantum chromodynamics and provides accurate information for the determination of parton distribution functions of the proton. This is the most precise lepton charge asymmetry measurement to date.
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30.
  • Abazov, V. M., et al. (author)
  • Measurement of the forward-backward asymmetry in Lambda(0)(b) and (Lambda)over-bar(b)(0) baryon production in p(p)over-bar collisions at root s=1.96 TeV
  • 2015
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 91:7
  • Journal article (peer-reviewed)abstract
    • We measure the forward-backward asymmetry in the production of Lambda(0)(b) and (Lambda) over bar (0)(b) baryons as a function of rapidity in p (p) over bar collisions at root s = 1.96 TeV using 10.4 fb(-1) of data collected with the D0 detector at the Fermilab Tevatron collider. The asymmetry is determined by the preference of Lambda(0)(b) or (Lambda) over bar (0)(b) particles to be produced in the direction of the beam protons or antiprotons, respectively. The measured asymmetry integrated over rapidity y in the range 0.1 < vertical bar y vertical bar < 2.0 is A = 0.04 +/- 0.07(stat) +/- 0.02(syst).
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31.
  • Abazov, V. M., et al. (author)
  • Measurement of the Forward-Backward Asymmetry in the Production lof B-+/- Mesons in p(p)over-bar Collisions at root s=1.96 TeV
  • 2015
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 114:5
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the forward-backward asymmetry in the production of B-+/- mesons, A(FB)(B-+/-) using B-+/- -> J/ Psi K-+/- decays in 10.4 fb(-1) of p (p) over bar collisions at root s = 1.96 TeV collected by the D0 experiment during Run II of the Tevatron collider. A nonzero asymmetry would indicate a preference for a particular flavor, i.e., b quark or (b) over bar antiquark, to be produced in the direction of the proton beam. We extract A(FB) (B-+/-) from a maximum likelihood fit to the difference between the numbers of forward-and backward-produced B-+/- mesons. We measure an asymmetry consistent with zero: A(FB) (B-+/-) = [-0.24 +/- 0.41 (stat) +/- 0.19 (syst)] %.
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32.
  • Abazov, V. M., et al. (author)
  • Measurement of the forward-backward asymmetry of Lambda and (Lambda)over-bar production in p(p)over-bar collisions
  • 2016
  • In: PHYSICAL REVIEW D. - 2470-0010. ; 93:3
  • Journal article (peer-reviewed)abstract
    • We study Lambda and (Lambda) over bar production asymmetries in p (p) over bar -> Lambda((Lambda) over bar )X, p (p) over bar -> J/psi Lambda((Lambda) over bar )X, and p (p) over bar -> mu(+/-)Lambda((Lambda) over bar )X events recorded by the D0 detector at the Fermilab Tevatron collider at root s = 1.96 TeV. We find an excess of Lambda's ((Lambda) over bar 's) produced in the proton (antiproton) direction. This forward-backward asymmetry is measured as a function of rapidity. We confirm that the (Lambda) over bar/Lambda production ratio, measured by several experiments with various targets and a wide range of energies, is a universal function of "rapidity loss," i.e., the rapidity difference of the beam proton and the lambda.
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33.
  • Abazov, V. M., et al. (author)
  • Measurement of the inclusive t(t)over-bar production cross section in p(p)over-bar collisions at root s=1.96 TeV and determination of the top quark pole mass
  • 2016
  • In: PHYSICAL REVIEW D. - 2470-0010. ; 94:9
  • Journal article (peer-reviewed)abstract
    • The inclusive cross section of top quark-antiquark pairs produced in p (p) over bar collisions at root s = 1.96 TeV is measured in the lepton + jets and dilepton decay channels. The data sample corresponds to 9.7 fb(-1) of integrated luminosity recorded with the D0 detector during Run II of the Fermilab Tevatron Collider. Employing multivariate analysis techniques we measure the cross section in the two decay channels and we perform a combined cross section measurement. For a top quark mass of 172.5 GeV, we measure a combined inclusive top quark-antiquark pair production cross section of sigma(t<(t)over bar) = 7.26 +/- 0.13(stat)(-0.50)(+0.57) (syst) pb which is consistent with standard model predictions. We also perform a likelihood fit to the measured and predicted top quark mass dependence of the inclusive cross section, which yields a measurement of the pole mass of the top quark. The extracted value is m(t) = 172.8 +/- 1.1(theo)(-3.1)(+3.3) (exp) GeV.
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34.
  • Abazov, V. M., et al. (author)
  • Measurement of the phi(eta)* distribution of muon pairs with masses between 30 and 500 GeV in 10.4 fb(-1) of p(p)over-bar collisions
  • 2015
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 91:7
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the distribution of the variable phi(eta)* for muon pairs with masses between 30 and 500 GeV, using the complete run II data set collected by the D0 detector at the Fermilab Tevatron proton-antiproton collider. This corresponds to an integrated luminosity of 10.4 fb(-1) at root s = 1.96 TeV. The data are corrected for detector effects and presented in bins of dimuon rapidity and mass. The variable phi(eta)* probes the same physical effects as the Z/gamma* boson transverse momentum, but is less susceptible to the effects of experimental resolution and efficiency. These are the first measurements at any collider of the phi(eta)* distributions for dilepton masses away from the Z --> l(+)l(-) boson mass peak. The data are compared to QCD predictions based on the resummation of multiple soft gluons.
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35.
  • Abazov, V. M., et al. (author)
  • Measurement of the ratio of inclusive cross sections sigma(p(p)over-bar) -> Z+2b jets/sigma(p((p)over-bar) -> Z+2 jets) in p((p)over-bar) collisions at root s=1.96 TeV
  • 2015
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 91:5
  • Journal article (peer-reviewed)abstract
    • We measure the ratio of cross sections, σ(pp¯→Z+2b jets)/σ(pp¯→Z+2 jets), for associated production of a Z boson with at least two jets with transverse momentum pjetT>20  GeV and pseudorapidity |ηjet|<2.5. This measurement uses data corresponding to an integrated luminosity of 9.7  fb−1 collected by the D0 experiment in Run II of Fermilab’s Tevatron pp¯ Collider at a center-of-mass energy of 1.96 TeV. The measured integrated ratio of 0.0236±0.0032 (stat)±0.0035 (syst) is in agreement with predictions from next-to-leading-order perturbative QCD and the Monte Carlo event generators pythia and alpgen.
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36.
  • Abazov, V. M., et al. (author)
  • Measurement of the top quark mass using the matrix element technique in dilepton final states
  • 2016
  • In: PHYSICAL REVIEW D. - 2470-0010. ; 94:3
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the top quark mass in p (p) over bar collisions at a center-of-mass energy of 1.96 TeV at the Fermilab Tevatron collider. The data were collected by the D0 experiment corresponding to an integrated luminosity of 9.7 fb(-1). The matrix element technique is applied to t (t) over bar events in the final state containing leptons (electrons or muons) with high transverse momenta and at least two jets. The calibration of the jet energy scale determined in the lepton + jets final state of t (t) over bar decays is applied to jet energies. This correction provides a substantial reduction in systematic uncertainties. We obtain a top quark mass of m(t) = 173.93 +/- 1.84 GeV.
  •  
37.
  • Abazov, V. M., et al. (author)
  • Measurement of the W plus b-jet and W plus c-jet differential production cross sections in p (p)over-bar collisions at root s=1.96 TeV
  • 2015
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 743, s. 6-14
  • Journal article (peer-reviewed)abstract
    • We present a measurement of the cross sections for the associated production of a W boson with at least one heavy quark jet, b or c, in proton-antiproton collisions. Data corresponding to an integrated luminosity of 8.7 fb(-1) recorded with the D0 detector at the Fermilab Tevatron p (p) over bar Collider at root s = 1.96 TeV are used to measure the cross sections differentially as a function of the jet transverse momenta in the range 20 to 150 GeV. These results are compared to calculations of perturbative QCD theory as well as predictions from Monte Carlo generators.
  •  
38.
  • Abazov, V. M., et al. (author)
  • Measurement of top quark polarization in t(t)over-bar lepton+jets final states
  • 2017
  • In: PHYSICAL REVIEW D. - 2470-0010. ; 95:1
  • Journal article (peer-reviewed)abstract
    • We present a measurement of top quark polarization in t (t) over bar pair production in p (p) over bar collisions at root s = 1.96 TeV using data corresponding to 9.7 fb(-1) of integrated luminosity recorded with the D0 detector at the Fermilab Tevatron Collider. We consider final states containing a lepton and at least three jets. The polarization is measured through the distribution of lepton angles along three axes: the beam axis, the helicity axis, and the transverse axis normal to the t (t) over bar production plane. This is the first measurement of top quark polarization at the Tevatron using lepton + jet final states and the first measurement of the transverse polarization in t (t) over bar production. The observed distributions are consistent with standard model predictions of nearly no polarization.
  •  
39.
  • Abazov, V. M., et al. (author)
  • Precise measurement of the top quark mass in dilepton decays using optimized neutrino weighting
  • 2016
  • In: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 752, s. 18-26
  • Journal article (peer-reviewed)abstract
    • We measure the top quark mass in dilepton final states of t (t) over bar events in p (p) over bar collisions at root s = 1.96 TeV, using data corresponding to an integrated luminosity of 9.7 fb(-1) at the Fermilab Tevatron Collider. The analysis features a comprehensive optimization of the neutrino weighting method to minimize the statistical uncertainties. We also improve the calibration of jet energies using the calibration determined in t (t) over bar -> lepton + jets events, which reduces the otherwise limiting systematic uncertainty from the jet energy scale. The measured top quark mass is m(t) = 173.32 +/- 1.36(stat) +/- 0.85(syst) GeV.
  •  
40.
  • Abazov, V. M., et al. (author)
  • Precision measurement of the top-quark mass in lepton plus jets final states
  • 2015
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 91:11
  • Journal article (peer-reviewed)abstract
    • We measure the mass of the top quark in lepton + jets final states using the full sample of p (p) over bar collision data collected by the D0 experiment in Run II of the Fermilab Tevatron Collider at root s = 1.96 TeV, corresponding to 9.7 fb(-1) of integrated luminosity. We use a matrix element technique that calculates the probabilities for each event to result from t (t) over bar production or background. The overall jet energy scale is constrained in situ by the mass of the W boson. We measure m(t) = 174.98 +/- 0.76 GeV. This constitutes the most precise single measurement of the top-quark mass.
  •  
41.
  • Abazov, V. M., et al. (author)
  • Search for Violation of CPT and Lorentz Invariance in B-s(0) Meson Oscillations
  • 2015
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 115:16
  • Journal article (peer-reviewed)abstract
    • We present the first search for CPT-violating effects in the mixing of B-s(0) mesons using the full Run II data set with an integrated luminosity of 10.4 fb(-1) of proton-antiproton collisions collected using the D0 detector at the Fermilab Tevatron Collider. We measure the CPT-violating asymmetry in the decay B-s(0) -> mu D-+/-(s)+/- as a function of celestial direction and sidereal phase. We find no evidence for CPT-violating effects and place limits on the direction and magnitude of flavor-dependent CPT- and Lorentz-invariance violating coupling coefficients. We find 95% confidence intervals of Delta a(perpendicular to) < 1.2 x 10(-12) GeV and (-0.8 < Delta a(T) - 0.396 Delta a(Z) < 3.9) x 10(-13) GeV.
  •  
42.
  • Abazov, V. M., et al. (author)
  • Simultaneous measurement of forward-backward asymmetry and top polarization in dilepton final states from t(t)over-bar production at the Tevatron
  • 2015
  • In: Physical Review D. - 1550-7998 .- 1550-2368. ; 92:5
  • Journal article (peer-reviewed)abstract
    • We present a simultaneous measurement of the forward-backward asymmetry and the top-quark polarization in t (t) over bar production in dilepton final states using 9.7 fb(-1) of proton-antiproton collisions at root s = 1.96 TeV with the D0 detector. To reconstruct the distributions of kinematic observables we employ a matrix element technique that calculates the likelihood of the possible t (t) over bar kinematic configurations. After accounting for the presence of background events and for calibration effects, we obtain a forward-backward asymmetry of A(t (t) over bar) = (15.0 +/- 6.4(stat) +/- 4.9(syst)) % and a top-quark polarization times spin analyzing power in the beam basis of kappa P = (7.2 +/- 10.5(stat) +/- 4.2(syst)) %, with a correlation of -56% between the measurements. If we constrain the forward-backward asymmetry to its expected standard model value, we obtain a measurement of the top polarization of kappa P = (11.3 +/- 9.1(stat) +/- 1.9(syst)) %. If we constrain the top polarization to its expected standard model value, we measure a forward-backward asymmetry of A(t (t) over bar) = (17.5 +/- 5.6(stat) +/- 3.1(syst)) %. A combination with the D0 A(t (t) over bar) measurement in the lepton + jets final state yields an asymmetry of A(t (t) over bar) = (11.8 +/- 2.5(stat) +/- 1.3(syst)) %. Within their respective uncertainties, all these results are consistent with the standard model expectations.
  •  
43.
  • Abazov, V. M., et al. (author)
  • Study of double parton interactions in diphoton plus dijet events in p<(p)over bar> collisions at root s = 1.96 TeV
  • 2016
  • In: PHYSICAL REVIEW D. - 2470-0010. ; 93:5
  • Journal article (peer-reviewed)abstract
    • We use a sample of diphoton + dijet events to measure the effective cross section of double parton interactions, which characterizes the area containing the interacting partons in proton-antiproton collisions, and find it to be sigma(eff) = 19.3 +/- 1.4(stat) +/- 7.8(syst) mb. The sample was collected by the D0 detector at the Fermilab Tevatron collider in p (p) over bar collisions at root s = 1.96 TeV and corresponds to an integrated luminosity of 8.7 fb(-1).
  •  
44.
  • Abazov, V. M., et al. (author)
  • Study of the X-+/-(5568) state with semileptonic decays of the B-s(0) meson
  • 2018
  • In: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 97:9
  • Journal article (peer-reviewed)abstract
    • We present a study of the X-+/-(5568) using semileptonic decays of the B-s(0) meson using the full run II integrated luminosity of 10.4 fb(-1) in proton-antiproton collisions at a center of mass energy of 1.96 TeV collected with the DO detector at the Fermilab Tevatron Collider. We report evidence for a narrow structure, X-+/-(5568), in the decay sequence X-+/-(5568) -> B-s(0) pi(+/-) where B-s(0)-> mu(-/+) (DsX)-X-+/-, D-s(+/-)-> phi pi(+/-)which is consistent with the previous measurement by the DO Collaboration in the hadronic decay mode, X-+/-(5568) -> B-s(0)pi(+/-) where B-s(0 )-> J/psi phi. The mass and width of this state are measured using a combined fit of the hadronic and semileptonic data, yielding m = 5566.9(-3.1)(+3.2)(stat)(-1.2)(+0.6)(syst) MeV/c(2), Gamma = 18.6(-6.1)(+7.9)(stat)(-3.8)(+3.5) (syst) McV/c(2) with a significance of 6.7 sigma.
  •  
45.
  • 2019
  • Journal article (peer-reviewed)
  •  
46.
  •  
47.
  •  
48.
  •  
49.
  • Menden, MP, et al. (author)
  • Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
  • 2019
  • In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 2674-
  • Journal article (peer-reviewed)abstract
    • The effectiveness of most cancer targeted therapies is short-lived. Tumors often develop resistance that might be overcome with drug combinations. However, the number of possible combinations is vast, necessitating data-driven approaches to find optimal patient-specific treatments. Here we report AstraZeneca’s large drug combination dataset, consisting of 11,576 experiments from 910 combinations across 85 molecularly characterized cancer cell lines, and results of a DREAM Challenge to evaluate computational strategies for predicting synergistic drug pairs and biomarkers. 160 teams participated to provide a comprehensive methodological development and benchmarking. Winning methods incorporate prior knowledge of drug-target interactions. Synergy is predicted with an accuracy matching biological replicates for >60% of combinations. However, 20% of drug combinations are poorly predicted by all methods. Genomic rationale for synergy predictions are identified, including ADAM17 inhibitor antagonism when combined with PIK3CB/D inhibition contrasting to synergy when combined with other PI3K-pathway inhibitors in PIK3CA mutant cells.
  •  
50.
  • Tinetti, Giovanna, et al. (author)
  • The EChO science case
  • 2015
  • In: Experimental astronomy. - : Springer Science and Business Media LLC. - 0922-6435 .- 1572-9508. ; 40:2-3, s. 329-391
  • Journal article (peer-reviewed)abstract
    • The discovery of almost two thousand exoplanets has revealed an unexpectedly diverse planet population. We see gas giants in few-day orbits, whole multi-planet systems within the orbit of Mercury, and new populations of planets with masses between that of the Earth and Neptune-all unknown in the Solar System. Observations to date have shown that our Solar System is certainly not representative of the general population of planets in our Milky Way. The key science questions that urgently need addressing are therefore: What are exoplanets made of? Why are planets as they are? How do planetary systems work and what causes the exceptional diversity observed as compared to the Solar System? The EChO (Exoplanet Characterisation Observatory) space mission was conceived to take up the challenge to explain this diversity in terms of formation, evolution, internal structure and planet and atmospheric composition. This requires in-depth spectroscopic knowledge of the atmospheres of a large and well-defined planet sample for which precise physical, chemical and dynamical information can be obtained. In order to fulfil this ambitious scientific program, EChO was designed as a dedicated survey mission for transit and eclipse spectroscopy capable of observing a large, diverse and well-defined planet sample within its 4-year mission lifetime. The transit and eclipse spectroscopy method, whereby the signal from the star and planet are differentiated using knowledge of the planetary ephemerides, allows us to measure atmospheric signals from the planet at levels of at least 10(-4) relative to the star. This can only be achieved in conjunction with a carefully designed stable payload and satellite platform. It is also necessary to provide broad instantaneous wavelength coverage to detect as many molecular species as possible, to probe the thermal structure of the planetary atmospheres and to correct for the contaminating effects of the stellar photosphere. This requires wavelength coverage of at least 0.55 to 11 mu m with a goal of covering from 0.4 to 16 mu m. Only modest spectral resolving power is needed, with R similar to 300 for wavelengths less than 5 mu m and R similar to 30 for wavelengths greater than this. The transit spectroscopy technique means that no spatial resolution is required. A telescope collecting area of about 1 m(2) is sufficiently large to achieve the necessary spectro-photometric precision: for the Phase A study a 1.13 m(2) telescope, diffraction limited at 3 mu m has been adopted. Placing the satellite at L2 provides a cold and stable thermal environment as well as a large field of regard to allow efficient time-critical observation of targets randomly distributed over the sky. EChO has been conceived to achieve a single goal: exoplanet spectroscopy. The spectral coverage and signal-to-noise to be achieved by EChO, thanks to its high stability and dedicated design, would be a game changer by allowing atmospheric composition to be measured with unparalleled exactness: at least a factor 10 more precise and a factor 10 to 1000 more accurate than current observations. This would enable the detection of molecular abundances three orders of magnitude lower than currently possible and a fourfold increase from the handful of molecules detected to date. Combining these data with estimates of planetary bulk compositions from accurate measurements of their radii and masses would allow degeneracies associated with planetary interior modelling to be broken, giving unique insight into the interior structure and elemental abundances of these alien worlds. EChO would allow scientists to study exoplanets both as a population and as individuals. The mission can target super-Earths, Neptune-like, and Jupiter-like planets, in the very hot to temperate zones (planet temperatures of 300-3000 K) of F to M-type host stars. The EChO core science would be delivered by a three-tier survey. The EChO Chemical Census: This is a broad survey of a few-hundred exoplanets, which allows us to explore the spectroscopic and chemical diversity of the exoplanet population as a whole. The EChO Origin: This is a deep survey of a subsample of tens of exoplanets for which significantly higher signal to noise and spectral resolution spectra can be obtained to explain the origin of the exoplanet diversity (such as formation mechanisms, chemical processes, atmospheric escape). The EChO Rosetta Stones: This is an ultra-high accuracy survey targeting a subsample of select exoplanets. These will be the bright "benchmark" cases for which a large number of measurements would be taken to explore temporal variations, and to obtain two and three dimensional spatial information on the atmospheric conditions through eclipse-mapping techniques. If EChO were launched today, the exoplanets currently observed are sufficient to provide a large and diverse sample. The Chemical Census survey would consist of > 160 exoplanets with a range of planetary sizes, temperatures, orbital parameters and stellar host properties. Additionally, over the next 10 years, several new ground- and space-based transit photometric surveys and missions will come on-line (e.g. NGTS, CHEOPS, TESS, PLATO), which will specifically focus on finding bright, nearby systems. The current rapid rate of discovery would allow the target list to be further optimised in the years prior to EChO's launch and enable the atmospheric characterisation of hundreds of planets.
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