| 1. |
- Altheimer, A., et al.
(författare)
-
Boosted objects and jet substructure at the LHC. Report of BOOST2012, held at IFIC Valencia, 23rd-27th of July 2012
- 2014
-
Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044. ; 74:3
-
Tidskriftsartikel (refereegranskat)abstract
- This report of the BOOST2012 workshop presents the results of four working groups that studied key aspects of jet substructure. We discuss the potential of first-principle QCD calculations to yield a precise description of the substructure of jets and study the accuracy of state-of-the-art Monte Carlo tools. Limitations of the experiments' ability to resolve substructure are evaluated, with a focus on the impact of additional (pile-up) proton proton collisions on jet substructure performance in future LHC operating scenarios. A final section summarizes the lessons learnt from jet substructure analyses in searches for new physics in the production of boosted top quarks.
|
|
| 2. |
- Field, Christopher B., et al.
(författare)
-
Summary for Policymakers
- 2014
-
Ingår i: Climate Change 2014: Impacts, Adaptation, and Vulnerability. Part A: Global and SectoralAspects.. - 9781107415379 ; , s. 1-32
-
Bokkapitel (refereegranskat)
|
|
| 3. |
- Abdesselam, A., et al.
(författare)
-
Boosted objects : a probe of beyond the standard model physics
- 2011
-
Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 71:6, s. 1661-
-
Tidskriftsartikel (refereegranskat)abstract
- We present the report of the hadronic working group of the BOOST2010 workshop held at the University of Oxford in June 2010. The first part contains a review of the potential of hadronic decays of highly boosted particles as an aid for discovery at the LHC and a discussion of the status of tools developed to meet the challenge of reconstructing and isolating these topologies. In the second part, we present new results comparing the performance of jet grooming techniques and top tagging algorithms on a common set of benchmark channels. We also study the sensitivity of jet substructure observables to the uncertainties in Monte Carlo predictions.
|
|
| 4. |
- Khuyagbaatar, J., et al.
(författare)
-
48Ca+249Bk Fusion Reaction Leading to Element Z=117: Long-Lived α-Decaying 270Db and Discovery of 266Lr
- 2014
-
Ingår i: Physical Review Letters. - 1079-7114. ; 112:17
-
Tidskriftsartikel (refereegranskat)abstract
- The superheavy element with atomic number Z=117 was produced as an evaporation residue in the 48Ca+249Bk fusion reaction at the gas-filled recoil separator TASCA at GSI Darmstadt, Germany. The radioactive decay of evaporation residues and their α-decay products was studied using a detection setup that allowed measuring decays of single atomic nuclei with half-lives between sub-μs and a few days. Two decay chains comprising seven α decays and a spontaneous fission each were identified and are assigned to the isotope 294-117 and its decay products. A hitherto unknown α-decay branch in 270Db (Z=105) was observed, which populated the new isotope 266Lr (Z=103). The identification of the long-lived (T1/2=1.0+1.9−0.4 h) α-emitter 270Db marks an important step towards the observation of even more long-lived nuclei of superheavy elements located on an “island of stability.”
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
|
|
| 8. |
- Gruner-Nielsen, Lars, et al.
(författare)
-
Brillouin Suppressed Highly Nonlinear Fibers
- 2012
-
Ingår i: European Conference and Exhibition on Optical Communication, ECEOC 2012; Amsterdam; Netherlands; 16 September 2012 through 20 September 2012. - 9781557529503 ; , s. We.1.F.1-
-
Konferensbidrag (refereegranskat)abstract
- Methods for suppression of stimulated Brillouin scattering in highly nonlinear fibers are reviewed. Emphasis is paid to SBS suppression by aluminum doping of the core. New results for a HNLF with an aluminum doped core and reduced loss are presented.
|
|
| 9. |
- Gruner-Nielsen, Lars, et al.
(författare)
-
Silica-based highly nonlinear fibers with a high SBS threshold
- 2011
-
Ingår i: 2011 IEEE Winter Topicals, WTM 2011. - 9781424484287 ; , s. 171-172
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Results on the suppression of stimulated Brillouin scattering in highly non linear fibers with both germanium- and aluminum-doped cores based on spooling the fiber with a linear strain gradient are compared and presented.
|
|
| 10. |
- Panda, S. K., et al.
(författare)
-
Effect of spin orbit coupling and Hubbard U on the electronic structure of IrO2
- 2014
-
Ingår i: Physical Review B. Condensed Matter and Materials Physics. - 1098-0121 .- 1550-235X. ; 89:15, s. 155102-
-
Tidskriftsartikel (refereegranskat)abstract
- We have studied in detail the electronic structure of IrO2 including spin orbit coupling (SOC) and electronelectron interaction, both within the generalized gradient approximation plus Hubbard U (GGA+ U) and GGA plus dynamical mean field theory (GGA+ DMFT) approximations. Our calculations reveal that the Ir t(2g) states at the Fermi level largely retain the J(eff) = 1/2 character, suggesting that this complex spin orbit entangled state may be robust even in metallic IrO2. We have calculated the phase diagram for the ground state of IrO2 as a function of U and find a metal insulator transition that coincides with a magnetic phase change, where the effect of SOC is only to reduce the critical values of U necessary for the transition. We also find that dynamic correlations, as given by the GGA+ DMFT calculations, tend to suppress the spin- splitting, yielding a Pauli paramagnetic metal for moderate values of the Hubbard U. Our calculated optical spectra and photoemission spectra including SOC are in good agreement with experiment, demonstrating the importance of SOC in IrO2.
|
|
| 11. |
- Parmigiani, Francesca, et al.
(författare)
-
All-Optical Phase Regeneration of 40Gbit/s DPSK Signals in a Black‐Box Phase Sensitive Amplifier
- 2010
-
Ingår i: 2010 Conference on Optical Fiber Communication, Collocated National Fiber Optic Engineers Conference, OFC/NFOEC 2010; San Diego, CA; United States; 21 March 2010 through 25 March 2010. - 9781557528841 ; , s. PDPC3-
-
Konferensbidrag (refereegranskat)abstract
- We present a black‐box four wave mixingbased bit‐rate‐flexible phase sensitive amplifier and use it in the first demonstration of 40 Gbit/s DPSK phaseregeneration.
|
|
| 12. |
|
|
| 13. |
|
|
| 14. |
|
|
| 15. |
- Das, D., et al.
(författare)
-
Identical RNA-protein interactions in vivo and in vitro and a scheme of folding the newly synthesized proteins by ribosomes
- 2012
-
Ingår i: Journal of Biological Chemistry. - 0021-9258 .- 1083-351X. ; 287:44, s. 37508-37521
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Ribosomal PTC acts as a protein folding modulator in vivo and in vitro. Results: A fixed set of nucleotides in the PTC interacts to fold polypeptides in vivo and in vitro. Conclusion: Folding all proteins through interaction with the same set of nucleotides in PTC implies they have intrinsic homology. Significance: Hundreds of proteins showed an identical cumulative hydrophobicity plot for amino acids.
|
|
| 16. |
- Dasgupta, Jhimli, et al.
(författare)
-
Structural Basis of Oligosaccharide Receptor Recognition by Human Papillomavirus
- 2011
-
Ingår i: Journal of Biological Chemistry. - 0021-9258 .- 1083-351X. ; 286:4, s. 2617-2624
-
Tidskriftsartikel (refereegranskat)abstract
- High risk human papillomavirus types 16 (HPV16) and 18 (HPV18) can cause cervical cancer. Efficient infection by HPV16 and HPV18 pseudovirions requires interactions of particles with cell-surface receptor heparan sulfate oligosaccharide. To understand the virus-receptor interactions for HPV infection, we determined the crystal structures of HPV16 and HPV18 capsids bound to the oligosaccharide receptor fragment using oligomeric heparin. The HPV-heparin structures revealed multiple binding sites for the highly negatively charged oligosaccharide fragment on the capsid surface, which is different from previously reported virus-receptor interactions in which a single type of binding pocket is present for a particular receptor. We performed structure-guided mutagenesis to generate mutant viruses, and cell binding and infectivity assays demonstrated the functional role of viral residues involved in heparin binding. These results provide a basis for understanding virus-heparan sulfate receptor interactions critical for HPV infection and for the potential development of inhibitors against HPV infection.
|
|
| 17. |
- Ellis, A. D., et al.
(författare)
-
Future Directions to Realize Ultra-High Bit-Rate Transmission Systems
- 2010
-
Ingår i: Proceedings of OptoElectronics and Communications Conference, OECC 2010, Sapporo, Japan, 5-9 July 2010, invited paper..
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- In this paper we examine two potential future directions for the realization of ultra-high bit rate transmission systems.
|
|
| 18. |
|
|
| 19. |
|
|
| 20. |
|
|
| 21. |
|
|
| 22. |
|
|
| 23. |
|
|
| 24. |
- Jana, Somnath, et al.
(författare)
-
Atomic-scale chemical fluctuation in LaSrVMoO6, a proposed half-metallic antiferromagnet
- 2010
-
Ingår i: Physical Review B. Condensed Matter and Materials Physics. - 1098-0121 .- 1550-235X. ; 82:18
-
Tidskriftsartikel (refereegranskat)abstract
- Half-metallic antiferromagnets (HMAFMs) have been proposed theoretically long ago but have not been realized experimentally yet. Recently, a double perovskite compound, LaSrVMoO6, has been claimed to be an almost real HMAFM system. Here, we report detailed experimental and theoretical studies on this compound. Our results reveal that the compound is neither a half-metal nor an ordered antiferromagnet. Most importantly, an unusual chemical fluctuation is observed locally, which finally accounts for all the electronic and magnetic properties of this compound.
|
|
| 25. |
|
|
| 26. |
- Singh, A., et al.
(författare)
-
High glucose causes dysfunction of the human glomerular endothelial glycocalyx
- 2011
-
Ingår i: American journal of physiology. Renal physiology. - : American Physiological Society. - 1522-1466 .- 1931-857X. ; 300:1
-
Tidskriftsartikel (refereegranskat)abstract
- The endothelial glycocalyx is a gel-like layer which covers the luminal side of blood vessels. The glomerular endothelial cell (GEnC) glycocalyx is composed of proteoglycan core proteins, glycosaminoglycan (GAG) chains, and sialoglycoproteins and has been shown to contribute to the selective sieving action of the glomerular capillary wall. Damage to the systemic endothelial glycocalyx has recently been associated with the onset of albuminuria in diabetics. In this study, we analyze the effects of high glucose on the biochemical structure of the GEnC glycocalyx and quantify functional changes in its protein-restrictive action. We used conditionally immortalized human GEnC. Proteoglycans were analyzed by Western blotting and indirect immunofluorescence. Biosynthesis of GAG was analyzed by radiolabeling and quantified by anion exchange chromatography. FITC-albumin was used to analyze macromolecular passage across GEnC monolayers using an established in vitro model. We observed a marked reduction in the biosynthesis of GAG by the GEnC under high-glucose conditions. Further analysis confirmed specific reduction in heparan sulfate GAG. Expression of proteoglycan core proteins remained unchanged. There was also a significant increase in the passage of albumin across GEnC monolayers under high-glucose conditions without affecting interendothelial junctions. These results reproduce changes in GEnC barrier properties caused by enzymatic removal of heparan sulfate from the GEnC glycocalyx. They provide direct evidence of high glucose-induced alterations in the GEnC glycocalyx and demonstrate changes to its function as a protein-restrictive layer, thus implicating glycocalyx damage in the pathogenesis of proteinuria in diabetes.
|
|
| 27. |
- Singh, A., et al.
(författare)
-
Reactive Oxygen Species Modulate the Barrier Function of the Human Glomerular Endothelial Glycocalyx
- 2013
-
Ingår i: Plos One. - : Public Library of Science (PLoS). - 1932-6203. ; 8:2
-
Tidskriftsartikel (refereegranskat)abstract
- Reactive oxygen species (ROS) play a key role in the pathogenesis of proteinuria in glomerular diseases like diabetic nephropathy. Glomerular endothelial cell (GEnC) glycocalyx covers the luminal aspect of the glomerular capillary wall and makes an important contribution to the glomerular barrier. ROS are known to depolymerise glycosaminoglycan (GAG) chains of proteoglycans, which are crucial for the barrier function of GEnC glycocalyx. The aim of this study is to investigate the direct effects of ROS on the structure and function of GEnC glycocalyx using conditionally immortalised human GEnC. ROS were generated by exogenous hydrogen peroxide. Biosynthesis and cleavage of GAG chains was analyzed by radiolabelling (S35 and 3H-glucosamine). GAG chains were quantified on GEnC surface and in the cell supernatant using liquid chromatography and immunofluorescence techniques. Barrier properties were estimated by measuring trans-endothelial passage of albumin. ROS caused a significant loss of WGA lectin and heparan sulphate staining from the surface of GEnC. This lead to an increase in trans-endothelial albumin passage. The latter could be inhibited by catalase and superoxide dismutase. The effect of ROS on GEnC was not mediated via the GAG biosynthetic pathway. Quantification of radiolabelled GAG fractions in the supernatant confirmed that ROS directly caused shedding of HS GAG. This finding is clinically relevant and suggests a mechanism by which ROS may cause proteinuria in clinical conditions associated with high oxidative stress.
|
|
| 28. |
- Slavík, Radan, et al.
(författare)
-
All-optical phase and amplitude regenerator for next-generation telecommunications systems
- 2010
-
Ingår i: Nature Photonics. - 1749-4885 .- 1749-4893. ; 4:10, s. 690-695
-
Tidskriftsartikel (refereegranskat)abstract
- Fibre-optic communications systems have traditionally carried data using binary (on-off) encoding of the light amplitude. However, next-generation systems will use both the amplitude and phase of the optical carrier to achieve higher spectral efficiencies and thus higher overall data capacities. Although this approach requires highly complex transmitters and receivers, the increased capacity and many further practical benefits that accrue from a full knowledge of the amplitude and phase of the optical field more than outweigh this additional hardware complexity and can greatly simplify optical network design. However, use of the complex optical field gives rise to a new dominant limitation to system performance—nonlinear phase noise. Developing a device to remove this noise is therefore of great technical importance. Here, we report the development of the first practical (‘black-box’) all-optical regenerator capableof removing both phase and amplitude noise from binary phase-encoded optical communications signals.
|
|
| 29. |
- Tarafder, Kartick, et al.
(författare)
-
Pressure and Temperature Control of Spin-Switchable Metal-Organic Coordination Polymers from Ab Initio Calculations
- 2012
-
Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 109:7, s. 077203-
-
Tidskriftsartikel (refereegranskat)abstract
- We explore a combination of density-functional theory with supplemented Coulomb U (DFT + U) and ab initio molecular dynamics simulations to investigate the spin-crossover (SCO) phenomenon in coordination polymers. We demonstrate the applicability of the method for the case of bimetallic metal-organic framework Fe-2[Nb(CN)(8)] center dot (4-pyridinealdoxime)(8) center dot 2H(2)O [see S. Ohkoshi et al. Nat. Chem. 3, 564 (2011)]. Our study shows that this approach is capable of capturing the SCO transitions driven by pressure as well as temperature. In addition to discovering novel spin-state transitions, magnetic states involving changes in the long-range magnetic ordering pattern are achieved, thereby offering the tunability of spin states as well as the long-range order of the spins. We compare the SCO transition in the Fe-based framework with a computer designed Mn-based variant.
|
|
