| 1. |
- El-Seedi, Hesham R., et al.
(författare)
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Naturally occurring xanthones; latest investigations : isolation, structure elucidation and chemosystematic significance
- 2009
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Ingår i: Current Medicinal Chemistry. - : Bentham Science Publishers Ltd.. - 0929-8673 .- 1875-533X. ; 16:20, s. 2581-2626
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Forskningsöversikt (refereegranskat)abstract
- In this review, an updated literature survey covering the reports of naturally occurring xanthones in the period of 2005-2008 is presented. In some 143 studies, the isolation of 264 different xanthones from 36 plant species (representing 15 genera in 6 families of higher plants), 7 species of fungi, and 1 lichen species were reported. Of these, 122 compounds were isolated for the first time from nature. We discuss plant origin, the way of separation, and spectral analysis done for structure elucidation, along with a brief discussion of the chemosystematic significance.
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| 2. |
- El-Seedi, Hesham R., et al.
(författare)
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Essential oil analysis of Micromeria nubigena HBK and its antimicrobial activity
- 2008
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Ingår i: The journal of essential oil research. - 1041-2905 .- 2163-8152. ; 20:5, s. 452-456
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Tidskriftsartikel (refereegranskat)abstract
- Water-distilled essential oil from leaves and flowers of Micromeria nubigena H.B.K. (Lamiaceae) were analyzed by GC and GUMS systems. The major components identified were thymol (36.9%), carvacrol (16.7%), pulegone (10.8%), caryophyllene oxide (4.6%) and (E)-phytol (3.2%). The major volatiles released by beta P-glucosidase treatment of the aqueous plant residue were (Z)-3-hexenol (31.2%), (4-2-hexenol (18.3%) and delta-cadinene (3.4%). The oil showed significant antibacterial activity against Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia, and Pseudomonas aeruginosa, and antifungal activity against Candida albicans, Botrytis cinerea and Aspergillus niger, while the beta-glucosidase-liberated fraction was inactive.
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| 3. |
- El-Seedi, H, et al.
(författare)
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Cyclopeptide alkaloids
- 2007
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Ingår i: Phytochemistry Reviews. - : Springer Science and Business Media LLC. - 1568-7767 .- 1572-980X. ; 6:1, s. 143-165
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Tidskriftsartikel (refereegranskat)abstract
- In this review, we discuss cyclopeptide alkaloids, their plant origin, and the way of separation, spectral analysis done for structure elucidation, stereochemistry, and their biological activities. In addition, we discuss briefly the chemosystematic significance of the cyclopeptide alkaloids based on their discovery in the family Olacaceae.
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| 4. |
- Ibrahim, N. A., et al.
(författare)
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Constituents and biological activity of the chloroform extract and essential oil of Cupressus sempervirens
- 2009
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Ingår i: Chemistry of Natural Compounds. - : Springer Science and Business Media LLC. - 0009-3130 .- 1573-8388. ; 45:3, s. 309-313
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Tidskriftsartikel (refereegranskat)abstract
- The essential oil of the leaves of Cupressus sempervirens L. was isolated by hydrodistillation and tested against gram positive and gram negative bacteria, showing remarkable antimicrobial activity against Bacillus subtilis with minimum inhibitory concentration (MIC) 75%. The antiviral activity of the essential oil was tested against Herpes simplex virus type 1 (HSV-1), showing antiviral activity with virucidal percentages of 68.0% and 53.2% at concentrations of 1:32 and 1:64, respectively. We firstly reported the isolation of two epi-betulin esters of fatty acids from the CHCl3 fraction of Cupressus sempervirens L. leaves, which were isolated and purified using HPLC, and identified using PMR and MS. The CHCl3 fraction showed significant cytotoxicity against HeLa cells.
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