Endocytosis of Potential Contact Sensitizers by Human Dendritic Cells

• Several lines of evidence indicates that a population of lymphoid cells occurring in most organs of the body with a dendritic morphology is of prime importance in the initial stages of immune responses (1). Immunohistochemical distribution studies using various cell surfaces phenotypic markers has often been used to argue the probable importance of dendritic cells in tissues for the initial immune response (2,3). It has however proven difficult to compare these cells from all tissues functionally in vitro due to low yields and alteration of the phenotype when the cells are enzymatically dislodge from the tissues. Most studies have thus focused on the Langerhans cell of the skin, spleen dendritic cells and negatively selected dendritic cells from human peripheral blood.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Immunology in the medical area (hsv//eng)

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