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Factors related to ...
Factors related to the progression of joint destruction in rheumatoid arthritis.
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- Sjöblom, K G (författare)
- Skåne University Hospital
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- Saxne, Tore (författare)
- Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Petersson, H (författare)
- Skåne University Hospital
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visa fler...
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- Wollheim, Frank (författare)
- Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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visa färre...
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(creator_code:org_t)
- 1984
- 1984
- Engelska.
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Ingår i: Scandinavian Journal of Rheumatology. - 1502-7732. ; 13:1, s. 21-27
- Relaterad länk:
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https://lup.lub.lu.s...
Abstract
Ämnesord
Stäng
- In 103 (M=25, F=78) of 150 consecutive RA patients, values of the following variables were obtained at the start and end of a 2-year follow-up period: radiographic destruction score of hands and feet according to Larsen (Larsen index), Ritchie index, B-hemoglobin, ESR and plasma proteins (α1-antitrypsin, ceruloplasmin, CRP, fibrinogen, haptoglobin, orosomucoid, IgA, IgG, IgM, C3 and C4). 60% of the values of ΔLI (final minus initial value of Larsen index) were significantly larger than zero (11-44 units, p<0.05). ΔLI was larger in females than in males (p=0.11). Comparing women with duration of disease (DoD) 1-6 years versus 7-52 years, ΔLI was larger in the former group (p=0.005). Comparing women with the largest ΔLI (19-44 units) with the remainder ones (ΔLI=-9-18 units), CRP and haptoglobin was higher and IgM lower in the former group (p=0.03, 0.02 and 0.03 respectively). In women with DoD 1-6 years (and only in this interval) significant linear relationships were found between ALI and hemoglobin (r-0.52, p<0.01) Ritchie index, haptoglobin, CRP (r=0.41-0.46, p<0.05) and IgM (r=-0.43, p<0.05). The mean of repeated hemoglobin values correlated even more strongly with ΔLI (r=0.70, p<0.001). ΔLI was predicted quite well by an expression linear in hemoglobin, fibrinogen and IgM (R=0.84). Similar results were obtained when male patients were included. © 1984 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Nyckelord
- rheumatoid arthritis
- joint disorders
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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