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Does Omeprazole Imp...
Does Omeprazole Improve Antimicrobial Therapy Directed Towards Gastric Campylobacter Pylori in Patients with Antral Gastritis? : A Pilot Study
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- Unge, Peter (författare)
- Dept. of Internal Medicine, Sandviken Hospital, Dept. of Clinical Microbiology, Gävle Hospital, Dept. of Clinical Pathology and Cytology, Falun Hospital and Medical Dept., AB Hässle, Mölndal, Sweden
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- Gad, A. (författare)
- Dept. of Internal Medicine, Sandviken Hospital, Dept. of Clinical Microbiology, Gävle Hospital, Dept. of Clinical Pathology and Cytology, Falun Hospital and Medical Dept., AB Hässle, Mölndal, Sweden
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- Gnarpe, H. (författare)
- Dept. of Internal Medicine, Sandviken Hospital, Dept. of Clinical Microbiology, Gävle Hospital, Dept. of Clinical Pathology and Cytology, Falun Hospital and Medical Dept., AB Hässle, Mölndal, Sweden
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- Olsson, J. (författare)
- Dept. of Internal Medicine, Sandviken Hospital, Dept. of Clinical Microbiology, Gävle Hospital, Dept. of Clinical Pathology and Cytology, Falun Hospital and Medical Dept., AB Hässle, Mölndal, Sweden
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Dept of Internal Medicine, Sandviken Hospital, Dept. of Clinical Microbiology, Gävle Hospital, Dept. of Clinical Pathology and Cytology, Falun Hospital and Medical Dept., AB Hässle, Mölndal, Sweden (creator_code:org_t)
- 2009-07-08
- 1989
- Engelska.
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Ingår i: Scandinavian Journal of Gastroenterology. - : Informa UK Limited. - 0036-5521 .- 1502-7708. ; 24:s167, s. 49-54
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- This double-blind pilot study has been undertaken in order to investigate the effect of amoxicillin and pronounced suppression of gastric acid secretion on mucosal colonisation with Campylobacter pylori (CP). Twentyfour CP-positive patients were included in the study and assigned to 14 days of treatment in either one of the following three therapy groups: Group 1: Omeprazole 40 mgo.m. + Amoxicillin 750 mgb.i.d (9pat); Group 2: Omeprazole 40 mg o.m. (8 pat); Group 3: Amoxicillin 750 mg b.i.d (7 pat).Gastroscopy with biopsy for culture and histology was performed pre-entry, at cessation of therapy and four weeks later. In the group receiving omeprazole and amoxicillin in combination 5 out of 8 patients were negative for CP four weeks after stopping treatment, while in the amoxicillin and the omeprazole groups respectively one (1/7) and none (0/8) were negative. Except for one patient who was withdrawn because of severe diarrhoea, only minor adverse effects occurred.
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- MEDICINE
- MEDICIN
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