| 1. |
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| 2. |
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| 3. |
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| 4. |
- Hogberg, Göran, et al.
(författare)
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Depressed adolescents in a case-series were low in vitamin D and depression was ameliorated by vitamin D supplementation
- 2012
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Ingår i: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 101:7, s. 779-783
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Tidskriftsartikel (refereegranskat)abstract
- Aim: The relationship between depression in adolescents and vitamin D was studied in a case-series that included effects of vitamin D supplementation. Methods: Serum 25OH vitamin D (25OHD) levels in 54 Swedish depressed adolescents were investigated. Subjects with vitamin D deficiency were given vitamin D3 over 3 months (n = 48). To evaluate well-being and symptoms related to depression and vitamin D status, the WHO-5 well-being scale, the Mood and Feelings Questionnaire (MFQ-S) and a vitamin D deficiency scale were used. Results: Mean serum 25OHD in the depressed adolescents was 41 at baseline and 91 nmol/L (p < 0.001) after supplementation. Basal 25OHD levels correlated positively with well-being (p < 0.05). After vitamin D supplementation, well-being increased (p < 0.001) and there was a significant improvement in eight of the nine items in the vitamin D deficiency scale: depressed feeling (p < 0.001), irritability (p < 0.05), tiredness (p < 0.001), mood swings (p < 0.01), sleep difficulties (p < 0.01), weakness (p < 0.01), ability to concentrate (p < 0.05) and pain (p < 0.05). There was a significant amelioration of depression according to the MFQ-S (p < 0.05). Conclusion: This study showed low levels of vitamin D in 54 depressed adolescents, positive correlation between vitamin D and well-being, and improved symptoms related to depression and vitamin D deficiency after vitamin D supplementation.
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| 5. |
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| 6. |
- Ljungman, Gustaf, et al.
(författare)
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Incidence and Survival Analyses in Children with Solid Tumours Diagnosed in Sweden 1983-2007.
- 2011
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Ingår i: Acta paediatrica. - : Wiley. - 1651-2227 .- 0803-5253. ; 100:5, s. 750-757
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Tidskriftsartikel (refereegranskat)abstract
- Aim: Solid tumours constitute 40% of childhood malignancies. The Swedish Childhood Cancer Registry is population-based and includes all children with cancer reported from the six paediatric oncology centres in Sweden. The aim was to investigate incidence and survival. Methods: We used the new WHO ICCC-3 for reclassification of the patients. Incidence and survival analyses were performed in the study population. Results: 2 487 children (< 15 years) were diagnosed with solid tumours in Sweden 1983 - 2007. The distribution of diagnoses was similar to that reported in other studies. The annual incidence was 65.3/million children. The survival rates at 10 years follow up have improved significantly when comparing the two time periods 1983-95 and 1995-2007 (76 vs. 82%; p<0.01). Conclusions: The mean annual incidence of solid tumours in children was 65.3/ million and has been stable during the study period. Survival rates for solid tumours at 5, 10 and 20 years follow up were 80, 79 and 76%, respectively.
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| 7. |
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| 8. |
- Ljungman, Gustaf, et al.
(författare)
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Incidence and survival analyses in children with solid tumours diagnosed in Sweden between 1983 and 2007
- 2011
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Ingår i: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 100:5, s. 750-757
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Tidskriftsartikel (refereegranskat)abstract
- Aim: Solid tumours constitute 40% of childhood malignancies. The Swedish Childhood Cancer Registry is population based and includes all children with cancer reported from the six paediatric oncology centres in Sweden. The aim was to investigate incidence and survival. Methods: We used the new WHO ICCC-3 for reclassification of the patients. Incidence and survival analyses were performed in the study population. Results: Two thousand four hundred and eighty-seven children (< 15 years) were diagnosed with solid tumours in Sweden between 1983 and 2007. The distribution of diagnoses was similar to that reported in other studies. The annual incidence was 65.3 per million children. The survival rates at 10 years of follow-up have improved significantly when comparing the two time periods, 1983-1995 and 1995-2007 (76 vs. 82%; p < 0.01). Conclusions: The mean annual incidence of solid tumours in children was 65.3/million and has been stable during the study period. Survival rates for solid tumours at 5, 10 and 20 years follow-up were 80, 79 and 76%, respectively.
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| 9. |
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| 10. |
- Andersson Ersman, Peter, et al.
(författare)
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Fast-switching all-printed organic electrochemical transistors
- 2013
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Ingår i: Organic electronics. - : Elsevier. - 1566-1199 .- 1878-5530. ; 14:5, s. 1276-1280
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Tidskriftsartikel (refereegranskat)abstract
- Symmetric and fast (∼5 ms) on-to-off and off-to-on drain current switching characteristics have been obtained in screen printed organic electrochemical transistors (OECTs) including PEDOT:PSS (poly(3,4-ethylenedioxythiophene) doped with poly(styrene sulfonic acid)) as the active transistor channel material. Improvement of the drain current switching characteristics is made possible by including a carbon conductor layer on top of PEDOT:PSS at the drain electrode that is in direct contact with both the channel and the electrolyte of the OECT. This carbon conductor layer suppresses the effects from a reduction front that is generated in these PEDOT:PSS-based OECTs. In the off-state of these devices this reduction front slowly migrate laterally into the PEDOT:PSS drain electrode, which make off-to-on switching slow. The OECT including carbon electrodes was manufactured using only standard printing process steps and may pave the way for fully integrated organic electronic systems that operate at low voltages for applications such as logic circuits, sensors and active matrix addressed displays.
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| 11. |
- Andreassen, A. K., et al.
(författare)
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Everolimus Initiation and Early Calcineurin Inhibitor Withdrawal in Heart Transplant Recipients: A Randomized Trial
- 2014
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Ingår i: American Journal of Transplantation. - : Elsevier BV. - 1600-6135 .- 1600-6143. ; 14:8, s. 1828-1838
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Tidskriftsartikel (refereegranskat)abstract
- In a randomized, open-label trial, everolimus was compared to cyclosporine in 115 de novo heart transplant recipients. Patients were assigned within 5 days posttransplant to low-exposure everolimus (3-6 ng/mL) with reduced-exposure cyclosporine (n 56), or standard-exposure cyclosporine (n = 59), with both mycophenolate mofetil and corticosteroids. In the everolimus group, cyclosporine was withdrawn after 7-11 weeks and everolimus exposure increased (6-10 ng/mL). The primary efficacy end point, measured GFR at 12 months posttransplant, was significantly higher with everolimus versus cyclosporine (mean +/- SD: 79.8 +/- 17.7 mL/min/1.73m 2 vs. 61.5 +/- 19.6 mL/min/1.73m 2; p<0.001). Coronary intravascular ultrasound showed that the mean increase in maximal intimal thickness was smaller (0.03 mm [95% CI 0.01, 0.05 mm] vs. 0.08 mm [95% CI 0.05, 0.12 mm], p = 0.03), and the incidence of cardiac allograft vasculopathy (CAV) was lower (50.0% vs. 64.6%, p = 0.003), with everolimus versus cyclosporine at month 12. Biopsy-proven acute rejection after weeks 7-11 was more frequent with everolimus (p = 0.03). Left ventricular function was not inferior with everolimus versus cyclosporine. Cytomegalovirus infection was less common with everolimus (5.4% vs. 30.5%, p<0.001); the incidence of bacterial infection was similar. In conclusion, everolimus-based immunosuppression with early elimination of cyclosporine markedly improved renal function after heart transplantation. Since postoperative safety was not jeopardized and development of CAV was attenuated, this strategy may benefit long-term outcome.
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| 12. |
- Annerbäck, Eva-Maria, et al.
(författare)
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Characteristic Features of Severe Child Physical Abuse-A Multi-informant Approach
- 2010
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Ingår i: Journal of family Violence. - : Springer. - 0885-7482 .- 1573-2851. ; 25:2, s. 165-172
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Tidskriftsartikel (refereegranskat)abstract
- Minor child physical abuse has decreased in Sweden since 1979, when a law banning corporal punishment of children was passed, but more serious forms have not decreased. The aim of this study was to examine risk and background factors in cases of severe child abuse reported to the police. Files from different agencies (e.g., Social services, Adult and Child psychiatry and Pediatric clinic) for 20 children and 34 caretakers were studied. An accumulation of risk factors was found. It is concluded that when the following four factors are present, there is a risk for severe child abuse: 1) a person with a tendency to use violence in conflict situations; 2) a strong level of stress on the perpetrator and the family; 3) an insufficient social network that does not manage to protect the child; 4) a child that does not manage to protect him or herself. Thus, multiple sources of information must be used when investigating child abuse.
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| 13. |
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| 14. |
- Annerbäck, Eva-Maria, 1948-, et al.
(författare)
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Child Physical Abuse and concurrence of other types of Child Abuse : associations with health and risk behaviors
- 2012
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Ingår i: International Journal of Child Abuse & Neglect. - : Elsevier BV. - 0145-2134 .- 1873-7757. ; 36:7-8, s. 585-595
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To examine the associations between child physical abuse and health problems/risk-taking behaviors among teen-agers. Further to evaluate concurrence of other types of abuse and how these alone and in addition to child physical abuse were associated with bad health status and risk-taking behaviors.Methods: A population-based survey was carried out in 2008 among all the pupils in two different grades (15 respectively 17 years old) in Södermanland County, Sweden (N=7 262). The response rate was 81.8 %. The pupils were asked among other things about their exposure to child physical abuse, exposure to parental intimate violence, bullying and exposure to being forced to engage in sexual acts. Adjusted analyses were conducted to estimate associations between exposure and illhealth/risk-taking behaviors.Results: Child physical abuse was associated with poor health and risk-taking behaviors with adjusted Odds Ratios (OR) ranging from 1.6 to 6.2. The associations were stronger when the pupils reported repeated abuse with OR ranging from 2.0 to 13.2. Also experiencing parental intimate partner violence, bullying and being forced to engage in sexual acts was associated with poor health and risk-taking behaviors with the same graded relationship to repeated abuse. Finally there was a cumulative effect of multiple abuse in the form of being exposed to child physical abuse plus other types of abuse and the associations increase with the number of concurrent abuse.Conclusions: This study provides strong indications that child abuse is a serious public health problem based on the clear links seen between abuse and poor health and behavioral problems. Consistent with other studies showing a graded relationship between experiences of abuse and poor health/risk-taking behaviors our study shows poorer outcomes for repeated and multiple abuse. Thus, our study calls for improvement of methods of comprehensive assessments, interventions and treatment in all settings where professionals meet young people.
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| 15. |
- Annerbäck, Eva-Maria, et al.
(författare)
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Prevalence and characteristics of child physical abuse in Sweden : findings from a population-based youth survey
- 2010
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Ingår i: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 99:8, s. 1229-1236
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Tidskriftsartikel (refereegranskat)abstract
- Aim: To examine prevalence rates of child physical abuse perpetrated by a parent/caretaker, abuse characteristics and the extent of disclosures. Methods: A population-based survey was carried out in 2008 amongst all the pupils in three different grades (n = 8494) in schools in Sodermanland County, Sweden. The pupils were asked about their exposure to violence and their experiences of parental intimate-partner violence. Data were analysed with bi- and multivariate models and a comparison between means of accumulating risk factors between three groups were performed. Results: A total of 15.2% of the children reported that they had been hit. There were strong associations between abuse and risk factors and there was a dose-response relationship between risks and reported abuse. It was shown that children who reported parental intimate-partner violence were at a considerably higher risk for abuse than other children and that only 7% of the children exposed to violence had disclosed this to authorities. Conclusion: Even though child abuse in Sweden has decreased markedly during the last 40 years, violence against children is still a considerable problem. It is a challenge to develop methods of assessment and interventions that will ensure that the violence and its underlying causes are directly addressed.
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| 16. |
- A'Roch, Roman, et al.
(författare)
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Left ventricular strain and peak systolic velocity : responses to controlled changes in load and contractility, explored in a porcine model
- 2012
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Ingår i: Cardiovascular Ultrasound. - : BioMed Central. - 1476-7120. ; 10:1
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Tissue velocity echocardiography is increasingly used to evaluate global and regional cardiac function. Previous studies have suggested that the quantitative measurements obtained during ejection are reliable indices of contractility, though their load-sensitivity has been studied in different settings, but still remains a matter of controversy. We sought to characterize the effects of acute load change (both preload and afterload) and change in inotropic state on peak systolic velocity and strain as a measure of LV contractility.METHODS: Thirteen anesthetized juvenile pigs were studied, using direct measurement of left ventricular pressure and volume and transthoracic echocardiography. Transient inflation of a vena cava balloon catheter produced controlled load alterations. At least eight consecutive beats in the sequence were analyzed with tissue velocity echocardiography during the load alteration and analyzed for change in peak systolic velocities and strain during same contractile status with a controlled load alteration. Two pharmacological inotropic interventions were also included to generate several myocardial contractile conditions in each animal.RESULTS: Peak systolic velocities reflected the drug-induced changes in contractility in both radial and longitudinal axis. During the acute load change, the peak systolic velocities remain stable when derived from signal in the longitudinal axis and from the radial axis. The peak systolic velocity parameter demonstrated no strong relation to either load or inotropic intervention, that is, it remained unchanged when load was systematically and progressively varied (peak systolic velocity, longitudinal axis, control group beat 1- 5.72 +/- 1.36 with beat 8- 6.49 +/- 1.28 cm/sec, 95% confidence interval), with the single exception of the negative inotropic intervention group where peak systolic velocity decreased a small amount during load reduction (beat 1- 3.98 +/- 0.92 with beat 8- 2.72 +/- 0.89 cm/sec). Systolic strain, however, showed a clear degree of load-dependence.CONCLUSIONS: Peak systolic velocity appears to be load-independent as tested by beat-to-beat load reduction, while peak systolic strain appears to be load-dependent in this model. Peak systolic velocity, in a controlled experimental model where successive beats during load alteration are assessed, has a strong relation to contractility. Peak systolic velocity, but not peak strain rate, is largely independent of load, in this model. More study is needed to confirm this finding in the clinical setting.
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| 17. |
- A'Roch, Roman, et al.
(författare)
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Left ventricular twist is load-dependent as shown in a large animal model with controlled cardiac load
- 2012
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Ingår i: Cardiovascular Ultrasound. - : BioMed Central. - 1476-7120. ; 10
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Left ventricular rotation and twist can be assessed noninvasively by speckle tracking echocardiography. We sought to characterize the effects of acute load change and change in inotropic state on rotation parameters as a measure of left ventricular (LV) contractility.METHODS: Seven anesthetised juvenile pigs were studied, using direct measurement of left ventricular pressure and volume and simultaneous transthoracic echocardiography. Transient inflation of an inferior vena cava balloon (IVCB) catheter produced controlled load reduction. First and last beats in the sequence of eight were analysed with speckle tracking (STE) during the load alteration and analysed for change in rotation/twist during controlled load alteration at same contractile status. Two pharmacological inotropic interventions were also included to examine the same hypothesis in additionally conditions of increased and decreased myocardial contractility in each animal. Paired comparisons were made for different load states using the Wilcoxon's Signed Rank test.RESULTS: The inferior vena cava balloon occlusion (IVCBO) load change compared for first to last beat resulted in LV twist increase (11.67degrees +/-2.65degrees vs. 16.17degrees +/-3.56degrees respectively, p < 0.004) during the load alteration and under adrenaline stimulation LV twist increase 12.56degrees +/-5.1degrees vs. 16.57degrees +/-4.6degrees (p < 0.013), and though increased, didn't reach significance in negative inotropic condition. Untwisting rate increased significantly at baseline from 41.7degrees/s +/-41.6degrees/s vs.122.6degrees/s +/-55.8degrees/s (P < 0.039) and under adrenaline stimulation untwisting rate increased (55.3degrees/s +/-3.8degrees/s vs.111.4degrees/s +/-24.0degrees/s (p < 0.05), but did not systematically changed in negative inotropic condition.CONCLUSIONS: Peak systolic LV twist and peak early diastolic untwisting rate are load dependent. Differences in LV load should be included in the interpretation when serial measures of twist are compared.
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| 18. |
- Blomqvist, Göran, 1963-, et al.
(författare)
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Damning från flygaskstabiliserade grusvägar
- 2012
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Obundna vägar dammar genom trafikens framfart över dem. Sådan damning kan leda till trafiksäkerhets- och hälsorisker, olägenheter för närboende och ett accelererat nedbrytande av grusvägens slitlager. Det har funnits misstanke om att grusvägar där bärlagret stabiliserats med inblandning av flygaska skulle damma mer än konventionella grusvägar. Därför undersöktes damningen vid två fältlokaler där både asksträckor och konventionellt byggda sträckor fanns. Forskningsuppgiften var att jämföra damningen och svara på frågan om askvägar dammar mer än de konventionellt byggda vägarna. Dessutom skulle spridningen av damm till omgivningen kartläggas och förekomsten av aska i det uppvirvlade dammet detekteras. Projektet genomförs som ett samarbetsprojekt mellan VTI, SGI och Högskolan Dalarna, men även IVL har varit med i projektgruppen. Resultaten riktar sig till planerare och drift- och underhållsansvariga hos väghållare, entreprenörer och myndigheter. Fältmätningarna har innefattat såväl väletablerade som innovativa mätmetoder för bestämning av damning och sådana faktorer som påverkar damning som grusslitlagrets vattenkvot och kornstorleksfördelning.
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| 19. |
- Blomqvist, Göran, et al.
(författare)
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The environmental sub-model of the Swedish Winter Model : updated algorithms for the description of salt damage to roadside environment
- 2010
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Ingår i: Sustainable winter service for road users. - Paris : La Défense.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Modeling the impact of the use of chemical anti-/deicing on the roadside environment requires knowledge of the roadside exposure to salt, the vulnerability or dose-response relationship of the modeled environmental subjects and, preferably, the “cost” of the following impacts. The results presented in this paper are the first tentative test runs of the environmental sub-model of the Swedish Winter model. The environmental cost will in this case study be the cost for vegetation damage larger than a chosen accepted level of damage, and a cost for groundwater protection installations. The total environmental cost in this small case study will roughly be between 1.5 and 2.5 MSEK.
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| 20. |
- Boman, Krister K, et al.
(författare)
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Disability, body image and sports/physical activity in adult survivors of childhood CNS tumors: population-based outcomes from a cohort study.
- 2013
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Ingår i: Journal of neuro-oncology. - : Springer Science and Business Media LLC. - 1573-7373 .- 0167-594X. ; 112:1, s. 99-106
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Tidskriftsartikel (refereegranskat)abstract
- Childhood CNS tumor survivors risk health and functional impairments that threaten normal psychological development and self-perception. This study investigated the extent to which health and functional ability predict adult survivors' body image (BI) and self-confidence regarding sports and physical activity. The study cohort covered 708 eligible ≥18year old CNS tumor survivors, and data from 528 (75%) were analyzed. Disability was estimated using the Health Utilities Index™ Mark2/3, a multidimensional self-report instrument. Physical self-confidence in terms of BI and sports/physical activity-related self-confidence (SPAS) were assessed using the BI and the Sports/Athletics modules of a standardized self-report assessment scale. In adjusted regression models, global health and functional status (GHFS) predicted BI (B=0.94, 95% CI 0.69-1.19) and SPAS (B=0.79, 95% CI 0.55-1.04). Emotion and pain, and to a lesser degree cognition, speech and vision disability, were associated with poorer BI and SPAS. Gender, sub-diagnosis, and time since diagnosis influenced the relationship between health status and physical self-confidence outcomes. Females had poorer GHFS, BI and SPAS than males. Decreased health and functional ability following childhood CNS cancer intrudes on physical self-confidence, with females being at heightened risk for both disability and negative self-confidence. Identified disability and gender-related risk calls for a follow-up plan that integrates treatment of psychological sequelae in lifetime monitoring of childhood CNS tumor survivors to restore and protect self-image and self-confidence, essential mental health correlates. An expanded plan should recognize the need for such services, optimizing life-long quality of survival for CNS tumor survivors.
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| 21. |
- Bosson, Emma, et al.
(författare)
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Exchange and pathways of deep and shallow groundwater in different climate and permafrost conditions using the Forsmark site, Sweden, as an example catchment
- 2013
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Ingår i: Hydrogeology Journal. - : Springer Nature. - 1431-2174 .- 1435-0157. ; 21:1, s. 225-237
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Tidskriftsartikel (refereegranskat)abstract
- This study simulates and quantifies the exchange and the pathways of deep and shallow groundwater flow and solute transport under different climate and permafrost conditions, considering the example field case of the coastal Forsmark catchment in Sweden. A number of simulation scenarios for different climate and permafrost condition combinations have been performed with the three-dimensional groundwater flow and transport model MIKE SHE. Results show generally decreasing vertical groundwater flow with depth, and smaller vertical flow under permafrost conditions than under unfrozen conditions. Also the overall pattern of both the vertical and the horizontal groundwater flow, and the water exchange between the deep and shallow groundwater systems, change dramatically in the presence of permafrost relative to unfrozen conditions. However, although the vertical groundwater flow decreases significantly in the presence of permafrost, there is still an exchange of water between the unfrozen groundwater system below the permafrost and the shallow groundwater in the active layer, via taliks. ‘Through taliks’ tend to prevail in areas that constitute groundwater discharge zones under unfrozen conditions, which then mostly shift to net recharge zones (through taliks with net downward flow) under permafrost conditions.
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| 22. |
- Bosson, Emma, et al.
(författare)
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Influences of shifts in climate, landscape, and permafrost on terrestrial hydrology
- 2012
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Ingår i: Journal of Geophysical Research. - 0148-0227 .- 2156-2202. ; 117
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Tidskriftsartikel (refereegranskat)abstract
- This study has simulated the terrestrial hydrology associated with different climate, landscape, and permafrost regime scenarios for the field case example of the relatively well characterized coastal catchment of Forsmark, Sweden. The regime scenarios were selected from long-term simulation results of climate, topographical, shoreline, and associated Quaternary deposit and vegetation development in this catchment with a time perspective of 100,000 years or more and were used as drivers for hydrological simulations with the three-dimensional model MIKE SHE. The hydrological simulations quantify the responses of different water flow and water storage components of terrestrial hydrology to shifts from the present cool temperate climate landscape regime in Forsmark to a possible future Arctic periglacial landscape regime with or without permafrost. The results show complexity and nonlinearity in the runoff responses to precipitation changes due to parallel changes in evapotranspiration, along with changes in surface and subsurface water storage dynamics and flow pathways through the landscape. The results further illuminate different possible perspectives of what constitutes wetter/drier landscape conditions, in contrast to the clearer concept of what constitutes a warmer/colder climate.
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| 23. |
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| 24. |
- Brattsand, Göran, et al.
(författare)
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Equalis/SFKK rekommenderar harmonisering av enheter vid hormonbestämningar -Något också för Norden?
- 2012
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Ingår i: Klinisk Biokemi i Norden. - 1101-2013. ; 24:4, s. 20-27
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Tidskriftsartikel (refereegranskat)abstract
- Equalis och Svensk Förening för Klinisk Kemi (SFKK) rekommenderar att de kliniska laboratorierna i Sverige använder enhetliga måttenheter vid hormonbestämningar för ökad jämförbarhet och patientsäkerhet. Vid analys i serum eller plasma med nuvarande metoder rekommenderas följande enheter:• Adrenokortikotropt hormon (ACTH): pmol/L• Insulin: mIE/L• Parathormon (PTH): pmol/L• Prolaktin: mIE/L• Tillväxthormon (GH): μg/L• Östradiol: pmol/L• Aldosteron: pmol/L• Reninkoncentration: mIE/L
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| 25. |
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| 26. |
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| 27. |
- Dellgren, Göran, 1961, et al.
(författare)
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Three decades of heart transplantation in Scandinavia: long-term follow-up
- 2013
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Ingår i: European Journal of Heart Failure. - : Wiley. - 1879-0844 .- 1388-9842. ; 15:3, s. 308-315
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Tidskriftsartikel (refereegranskat)abstract
- Aim Heart transplantation (HTx) has become a standard treatment for patients with end-stage heart disease. The aim of this study was to report the long-term outcome after HTx in Scandinavia. Methods and results During the period, 1983-2009,2333 HTxs were performed in 2293 patients (mean age 45 +/- 16 years, range 0-70,78% mate). The main indications for HTx were non-ischaemic cardiomyopathy (50%), ischaemic cardiomyopathy (34%), valvular cardiomyopathy (3%), congenital heart disease (7%), retransplantation (2%), and miscellaneous (4%). The registry consists of pre-operative data from recipients and donors, data from pre-operative procedures, and long-term follow-up data. Mean follow-up was 7.8 +/- 6.6 years (median 6.9, interquartile range 2.5-12.3, interval 0-27) and no patients were lost to follow-up. Long-term survival for HTx patients was 85, 76, 61, 43, and 30% at 1, 5, 10, 15, and 20 years of follow-up, respectively. Ten-year survival in patients bridged with mechanical circulatory support, in children, after retransplantation, and after concomitant other organ transplantation was 56, 74, 38, and 43%, respectively. Older patients (age >55 years) had a significantly worse survival (P < 0.001). Patients transplanted more recently had a significantly better survival (P < 0.001). In a multivariate Cox regression analysis, independent predictors of long-term survival were recipient age (P < 0.001), donor age (P < 0.001), diagnosis (P = 0.001), and era of transplantation (P < 0.001). Conclusions HTx in Scandinavia proves to have a significantly better survival among patients transplanted in the last decade. HTxs from mechanical circulatory support, in children, after retransplantation, and with concomitant other organ transplantation were performed with acceptable results.
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| 28. |
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| 29. |
- Denby, Bruce Rolstad, et al.
(författare)
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A coupled road dust and surface moisture model to predict non-exhaust road traffic induced particle emissions (NORTRIP). Part 1 : Road dust loading and suspension modelling
- 2013
-
Ingår i: Atmospheric Environment. - : Elsevier BV. - 1352-2310 .- 1873-2844. ; 77, s. 283-300
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Tidskriftsartikel (refereegranskat)abstract
- Non-exhaust traffic induced emissions are a major source of particle mass in most European countries. This is particularly important in Nordic and Alpine countries where winter time road traction maintenance occurs, e.g. salting and sanding, and where studded tyres are used. In this paper, Part 1, the road dust sub-model of a coupled road dust and surface moisture model (NORTRIP) is described. The model provides a generalised process based formulation of the non-exhaust emissions, with emphasis on the contribution of road wear, suspension, surface dust loading and the effect of road surface moisture (retention of wear particles and suspended emissions). The model is intended for use as a tool for air quality managers to help study the impact of mitigation measures and policies. We present a description of the road dust sub-model and apply the model to two sites in Stockholm and Copenhagen where seven years of data with surface moisture measurements are available. For the site in Stockholm, where studded tyres are in use, the model predicts the PM10 concentrations very well with correlations (R-2) in the range of R-2 = 0.76-0.91 for daily mean PM10. The model also reproduces well the impact of a reduction in studded tyres at this site. For the site in Copenhagen the correlation is lower, in the range 0.44-0.51. The addition of salt is described in the model and at both sites this leads to improved correlations due to additional salt emissions. For future use of the model a number of model parameters, e.g. wear factors and suspension rates, still need to be refined. The effect of sanding on PM10 emissions is also presented but more information will be required before this can be confidently applied for management applications. (C) 2013 Elsevier Ltd. All rights reserved.
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| 30. |
- Denby, Bruce Rolstad, et al.
(författare)
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A coupled road dust and surface moisture model to predict non-exhaust road traffic induced particle emissions (NORTRIP). Part 2 : Surface moisture and salt impact modelling
- 2013
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Ingår i: Atmospheric Environment. - : Elsevier. - 1352-2310 .- 1873-2844. ; 81, s. 485-503
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Tidskriftsartikel (refereegranskat)abstract
- Non-exhaust traffic induced emissions are a major source of airborne particulate matter in most European countries. This is particularly important in Nordic and Alpine countries where winter time road traction maintenance occurs, e.g. salting and sanding, and where studded tyres are used. Though the total mass generated by wear sources is a key factor in non-exhaust emissions, these emissions are also strongly controlled by surface moisture conditions. In this paper, Part 2, the road surface moisture submodel of a coupled road dust and surface moisture model (NORTRIP) is described.We present a description of the road surface moisture part of the model and apply the coupled model to seven sites in Stockholm, Oslo, Helsinki and Copenhagen over 18 separate periods, ranging from 3.5 to 24 months. At two sites surface moisture measurements are available and the moisture sub-model is compared directly to these observations. The model predicts the frequency of wet roads well at both sites, with an average fractional bias of -2.6%. The model is found to correctly predict the hourly surface state, wet or dry, 85% of the time. From the 18 periods modelled using the coupled model an average absolute fractional bias of 15% for PM10 concentrations was found. Similarly the model predicts the 90'th daily mean percentiles of PMio with an average absolute bias of 19% and an average correlation (R-2) of 0.49. When surface moisture is not included in the modelling then this average correlation is reduced to 0.16, demonstrating the importance of the surface moisture conditions. Tests have been carried out to assess the sensitivity of the model to model parameters and input data. The model provides a useful tool for air quality management and for improving our understanding of non-exhaust traffic emissions.
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| 31. |
- Do, Ron, et al.
(författare)
-
Common variants associated with plasma triglycerides and risk for coronary artery disease
- 2013
-
Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 45:11, s. 1345-
-
Tidskriftsartikel (refereegranskat)abstract
- Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery disease (CAD). However, it is unclear whether this association reflects causal processes. We used 185 common variants recently mapped for plasma lipids (P < 5 x 10(-8) for each) to examine the role of triglycerides in risk for CAD. First, we highlight loci associated with both low-density lipoprotein cholesterol (LDL-C) and triglyceride levels, and we show that the direction and magnitude of the associations with both traits are factors in determining CAD risk. Second, we consider loci with only a strong association with triglycerides and show that these loci are also associated with CAD. Finally, in a model accounting for effects on LDL-C and/or high-density lipoprotein cholesterol (HDL-C) levels, the strength of a polymorphism's effect on triglyceride levels is correlated with the magnitude of its effect on CAD risk. These results suggest that triglyceride-rich lipoproteins causally influence risk for CAD.
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| 32. |
- Egeskog, Andrea, 1981, et al.
(författare)
-
Integrating bioenergy and food production - A case study of combined ethanol and dairy production in Pontal, Brazil
- 2011
-
Ingår i: Energy for Sustainable Development. - : Elsevier BV. - 2352-4669 .- 0973-0826. ; 15:1, s. 8-16
-
Tidskriftsartikel (refereegranskat)abstract
- Increased Brazilian sugarcane ethanol production is expected in response to increasing domestic andinternational ethanol demand. The Pontal do Paranapanema region, located in the western parts of the SãoPaulo state, is one of the regions where sugarcane is expected to expand on a large scale. This expansion willmost likely affect small-scale dairy farmers in the region and may lead to displaced milk production.Interviews have been made with small-scale dairy farmers in areas where sugarcane has already beenestablished. These interviews show that many farmers who substitute milk production for sugarcaneproduction experience economic stagnation after the change. However, both systems can coexist, usingsugarcane residues as high-quality cattle feed. This feed can easily be made at the ethanol mills usingsugarcane residues and some additional protein and mineral supplements. Analyses indicate that the dairyfarmers can increase their income ten-fold by adopting this integrated system. The increased total output andhigher land-use efficiency in dairy production may counteract possible indirect land-use change. Greenhousegas emissions per unit of milk produced as well as liter ethanol produced depend on several factors, includingeffects of diverting bagasse from other uses to feed production.
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| 33. |
- Englund, Annika, et al.
(författare)
-
Changes in mortality and causes of death in the Swedish Down syndrome population
- 2013
-
Ingår i: American Journal of Medical Genetics. Part A. - : Wiley. - 1552-4825 .- 1552-4833. ; 161A:4, s. 642-649
-
Tidskriftsartikel (refereegranskat)abstract
- During the past few decades age at death for individuals with Down syndrome (DS) has increased dramatically. The birth frequency of infants with DS has long been constant in Sweden. Thus, the prevalence of DS in the population is increasing. The aim of the present study was to analyze mortality and causes of death in individuals with DS during the period 19692003. All individuals with DS that died between 1969 and 2003 in Sweden, and all individuals born with DS in Sweden between 1974 and 2003 were included. Data were obtained from the Swedish Medical Birth Register, the Swedish Birth Defects Register, and the National Cause of Death Register. Median age at death has increased by 1.8 years per year. The main cause of death was pneumonia. Death from congenital heart defects decreased. Death from atherosclerosis was rare but more frequent than reported previously. Dementia was not reported in any subjects with DS before 40 years of age, but was a main or contributing cause of death in 30% of the older subjects. Except for childhood leukemia, cancer as a cause of death was rare in all age groups. Mortality in DS, particularly infant mortality, has decreased markedly during the past decades. Median age at death is increasing and is now almost 60 years. Death from cancer is rare in DS, but death from dementia is common.
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| 34. |
- Eriksson, Louise, et al.
(författare)
-
Tema miljörisker : miljörisker och trafikanters beteenden
- 2011
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This report compiles the results from the project Theme Environmental risks. More specifically, the project concerned how different transport related environmental risks influence different road users and how their behaviour influence the environment. The project aimed at preparing for interdisciplinary research about environmental risks at VTI. The project was divided into three parts. The first subproject aimed at compiling literature about transport related environmental risks from psychological and economic perspectives, and in the second subproject a willingness to pay study was outlined where both economic and psychological principles were considered. In the third subproject, a simulator study was outlined. The focus was to study environmental effects of driving under controlled circumstances in the driving simulator. The report is divided into two parts. In part 1, the results from the literature review and the proposal for a willingness to pay study are described (subproject 1 and 2). This part is written in English. Part 2 contains a project outline for a simulator study in the form of an research project application (project 3). This part is written in Swedish.
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| 35. |
- Gatzinsky, Vladimir, 1966, et al.
(författare)
-
Impaired peripheral airway function in adults following repair of esophageal atresia.
- 2014
-
Ingår i: Journal of pediatric surgery. - : Elsevier BV. - 1531-5037 .- 0022-3468. ; 49:9, s. 1347-52
-
Tidskriftsartikel (refereegranskat)abstract
- Esophageal atresia (EA) often leads to persistent symptoms and impaired respiratory function in adulthood. The role of peripheral airways in this impairment has not been previously investigated. Furthermore, asthma-like symptoms are common in these patients.
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| 36. |
- Goodhew, Peter, et al.
(författare)
-
Concept Questions in Engineering: The Next Step
- 2012
-
Ingår i: 8th International CDIO Conference, Queensland University of Technology, Brisbane, Queensland, Australia, 1-4 July 2012.. - 9781921897344
-
Konferensbidrag (refereegranskat)abstract
- At last year’s conference in Copenhagen one of us reviewed existing banks of concept questions and initiated the collection of further questions from participants. In this paper/workshop we will report on progress with the collection and the deployment of this resource and take advice on its further development.
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| 37. |
- Granberg, Hjalmar, et al.
(författare)
-
Dynamics of moisture interaction with polyelectrolyte multilayers containing nanofibrillated cellulose
- 2012
-
Ingår i: Nordic Pulp & Paper Research Journal. - 0283-2631 .- 2000-0669. ; 27:2, s. 496-499
-
Tidskriftsartikel (refereegranskat)abstract
- Recent findings have shown that it is possible to use the Layer-by-Layer technique to create nanofibrillated cellulose / polyethyleneimine interference films whose colour change with relative humidity. This study uses different optical models to describe spectral ellipsometry measurements data of interference films and how the film properties alter in dry and humid environments. The results indicate that water condensation initially is filling the surface pores within seconds whereas relaxation of the film to adjust to the added water is a slower process that reaches a steady state after ~20 min. The maximum swelling ratio of the LbL films is almost independent of the number of layers within the film, but decreases considerably by crosslinking via heat treatment. The films show a distinct birefringence with optical axis perpendicular to the surface. Analysis of the moisture response with different optical models indicates that the films swell uniformly in the thickness direction with no separate water film on top. The results provide important understanding for the design of NFC based LbL films for visual moisture sensors and interactive security paper.
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| 38. |
- Gustafsson, Anton, et al.
(författare)
-
Have Computer - Will Travel : A Discourse Analysis of a 1:1 Initiative in Upper Secondary School.
- 2014
-
Ingår i: Procedia - Social and Behavioral Sciences. - : Elsevier BV. - 1877-0428. ; 141:0, s. 182-187
-
Tidskriftsartikel (refereegranskat)abstract
- The purpose of the presented study is to investigate how teachers and students renegotiate their positions within a pedagogical discourse where problems and possibilities are manifested through the new artifact, the personal computer. The sample consists of teachers and students at an upper secondary school in Sweden where all students have been provided with a personal laptop by their school. Information has been collected by the use of semi-structured interviews. The analysis mainly draws on Laclau & Mouffe’s theories of how subjects create discourses through articulations and then investigate qualitative differences between interviewees. The results indicate that teachers actively include some specific meanings of the computer while others are excluded. A recurring feature of this was the conflict of old and new practices with the introduction such as the perceived conflict between computers and textbooks. This relation remained controversial among teachers. The students had to negotiate the teachers’ definition of the computer because of the power relations, even though they could account for a far wider and more reflexive stance towards the potential of the computer.
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| 39. |
- Gustafsson, Anna-Maria, et al.
(författare)
-
CFD-modelling of natural convection in a groundwater-filled borehole heat exchanger
- 2010
-
Ingår i: Applied Thermal Engineering. - : Elsevier BV. - 1359-4311 .- 1873-5606. ; 30:6-7, s. 683-691
-
Tidskriftsartikel (refereegranskat)abstract
- In design of ground-source energy systems the thermal performance of the borehole heat exchangers is important. In Scandinavia, boreholes are usually not grouted but left with groundwater to fill the space between heat exchanger pipes and borehole wall. The common U-pipe arrangement in a groundwater-filled BHE has been studied by a three-dimensional, steady-state CFD model. The model consists of a 3 m long borehole containing a single U-pipe with surrounding bedrock. A constant temperature is imposed on the U-pipe wall and the outer bedrock wall is held at a lower constant temperature. The occurring temperature gradient induces a velocity flow in the groundwater-filled borehole due to density differences. This increases the heat transfer compared to stagnant water. The numerical model agrees well with theoretical studies and laboratory experiments. The result shows that the induced natural convective heat flow significantly decreases the thermal resistance in the borehole. The density gradient in the borehole is a result of the heat transfer rate and the mean temperature level in the borehole water. Therefore in calculations of the thermal resistance in groundwater-filled boreholes convective heat flow should be included and the actual injection heat transfer rate and mean borehole temperature should be considered. (C) 2009 Elsevier Ltd. All rights reserved.
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| 40. |
- Gustafsson, Christina, et al.
(författare)
-
Att arbeta i högskolan : utmaningar och möjligheter
- 2010. - 2
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Under de närmaste åren rekryteras ett betydande antal nya lärare av olika kategorier till högskolor och universitet. Det sker i en tid då studentgrupperna blir större och mer heterogena, då nationell och global konkurrens ökar. Samtidigt skärps de ekonomiska förutsättningarna och kraven på studenternas anställningsbarhet efter genomförd utbildning. En bra yrkesintroduktion ökar lärarnas möjligheter att lyckas väl i sin professionella yrkesutveckling. I boken problematiserar författarna såväl högskolornas uppdrag som förutsättningarna för högskolelärares arbete. De lyfter fram undervisningen i högskolan: föreläsningar, seminarier, handledning, examination, nätbaserad utbildning och värderingar. Boken behandlar även högskolelärares utvecklings- och karriärmöjligheter inklusive en diskussion om dokumentation av meriter. Den nya upplagan har omarbetats grundligt i ljuset av de förändringar som ägt rum på organisations- och styrningsnivå. Kapitlet om nätbaserad utbildning är helt omskrivet och ett kapitel om examination har tillkommit. Att arbeta i högskolan – utmaningar och möjligheter är lämplig för både nya och mer erfarna lärare inom högskolan.
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| 41. |
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| 42. |
- Gustafsson, Claes M, 1966, et al.
(författare)
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MTERF1 gives mtDNA an unusual twist.
- 2010
-
Ingår i: Cell metabolism. - : Elsevier BV. - 1932-7420 .- 1550-4131. ; 12:1, s. 3-4
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Expression of mtDNA is critical for biogenesis of the oxidative phosphorylation system, but the regulatory processes are poorly understood. Recent work in Cell (Yakubovskaya et al., 2010) reports a novel DNA-binding fold in mitochondrial transcription termination factor 1 (MTERF1), which causes unwinding and base eversion at its target mtDNA sequence.
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| 43. |
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| 44. |
- Gustafsson, Christina, et al.
(författare)
-
Teaching and Learning in Higher Education : challenges and Possibilities
- 2011
-
Bok (övrigt vetenskapligt/konstnärligt)abstract
- In the next few years a conciderable number of new teachers of different categories will be recruited to higher education institutions. This will also coincide with larger and more heterogeneous student groups and an increase in national and global competition. At the same time, the economic prerequisites and demands for students’ employability after university are becoming much more stringent. A good professional induction increases teachers’ opportunities of succeeding in their professional development.In the book the authors problematise the higher institutions’ mandate as the prerequisite for higher education teachers’ work. They highlight the various aspects of teaching in the higher educational institution: lectures, seminars, supervision, examinations, online education and values. The book also addresses the higher education teacher’s development and career possibilities and discusses the documentation of qualifications. This is the English version of Att arbeta i högskolan that was revised in 2010. Teaching and Learning in Higher Education – Challenges and Possibilities is suitable for new and more experienced teachers in a higher education context.
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| 45. |
- Gustafsson, David, et al.
(författare)
-
Distribuerade system för förbättrade snö- och avrinningsprognoser : Integration i hydrologiska modeller. Slutrapport
- 2012
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Det övergripande målet med projektet har varit att minska totala volymfelet i prognoser för vårflödesavrinningen samt att förbättra tids- och volym-bestämningen av flödespikarna för dessa. Projektet har fokuserat på att kombinera utveckling av modell- och mätteknik för att studera hur modellstrukturer och metoder för att integrera mätinformation (data-assimilering) kan optimeras i förhållande till tillgänglig snöinformation. Ett syfte har också varit att de utvecklade metoderna skall vara operationellt användbara och baserade på kostnads- och tidseffektiva mättekniker och modelleringsverktyg, samtidigt som de skall ge en betydande förbättring av prognoserna. I projektet har en rad mättekniker testats och vidareutvecklas (tex snökuddar, automatiska sensorer för snödjup- och densitet, samt markradartekniker). Störst fokus har varit på vidareutveckling av radarteknik för linjemätning av snötäckets djup, densitet och fuktighet. För torr snö har djup och densitet uppskattats med hjälp av radarvågornas snöutbredningshastighet direkt från radardata med ett flerkanalradarsystem, [så kallad ”common-mid point” (CMP) metod)]. För blöt snö krävs förutom utbrednings-hastigheten också information om snöns fuktighet för korrigering av uppskattningen av snöns densitet. Inom projektet har därför en ny metod utvecklats för bestämning av snös fuktighet baserad på det faktum att utsläckningen av radarsignalens amplitud beror på snöns fuktighet. Två olika hydrologiska modeller har använts inom projektet: SMHI:s nya vattenbalans- och vattenkvalitetsmodell HYPE samt en egenutvecklad modell. Den senare modellen har utvecklats för att kunna jämföra tillrinnings-prognosernas känslighet för val av snömodellstruktur (representation av processer och distribution i tid och rum). Modellen består av en rumsligt distribuerad snömodell kopplad till en odistribuerad avrinningsmodell (en förenklad variant av HBV-modellen). Modellen utvecklades inom det hydrologiska modelleringssystemet HYSS utvecklat på SMHI, men kan i princip kopplas till vilken modellplattform som helst. Snö-smältningen kan beräknas antingen med temperatur- och strålnings-indexmetod eller med energibalansmetod. Den rumsliga distribueringen kan göras antingen med ett 2-dimensionellt nät eller genom uppdelning av avrinningsområdet i representativa enheter baserad på klassificering av topografi (höjd, lutning väderstreck) och vegetation. HYPE-modellen har för närvarande en enklare snömodell än den egenutvecklade modellen, men erbjuder istället hög rumslig uppdelning, öppen källkod (HYPE Open Source Community) och en enkel hantering av drivdata och modelluppsättningar för nya områden genom den operationella sverigeapplikationen (S-HYPE). HYPE-modellen har därför använts för att göra projektets modellutveckling lättare tillgänglig för andra. Den har också använts för att jämföra värdet av assimilering av snödata med värdet av val av prognosdata för nederbörd och temperatur. På sikt kan den egenutvecklade snömodellen göras tillgänglig som en valbar modul i HYPE. En dataassimileringsrutin baserad på Ensemble Kalmanfilter (EnKF) har utvecklats för integrering av snöinformation i simuleringarna och har implementerats som en modul i HYPE. Med EnKF metoden uppdateras modelltillstånd som funktion av kovariansen mellan modelltillstånd och modellfel. Uppdateringen sker sekventiellt, det vill säga under simuleringens gång vartefter nya observationer tillkommer. Kovariansen mellan modelltillstånd och modellfel uppskattas genom att skapa en ensemble av modeller med en viss spridning i modelltillstånden. Spridningen genereras genom att köra flera parallella modeller med slumpmässiga avvikelser i drivvariabler och parametervärden. En styrka med metoden är att osäkerheter i observationer, modellparametrar och indata kan uppskattas var för sig och användas för en automatisk uppdatering av modelltillstånden. Resterande spridning i den uppdaterade prognosen nyttjas för skattning av osäkerheten i resultaten. Beräkningsbördan ökar jämfört med en enskild simulering (ca 100 ensemblemedlemmar behövs), men jämfört med andra dataassimileringsmetoder är EnKF metoden mycket effektiv. De flesta hydrologiska modeller använder samma tröskeltemperatur för att skilja på regn och snö för alla nederbördstillfällen Förhållanden högre upp i atmosfären påverkar emellertid också hur stor andel av nederbörden som faller som snö respektive regn vid en viss markytetemperatur. Situationen i atmosfären beror i sin tur till stor del på vilken typ av front (gräns mellan luftmassor med olika temperatur) som producerar nederbörden. Vi har visat att man kan minska andelen felklassad nederbörd genom att identifiera vilken typ av front (varm- eller kall) som orsakar nederbörden vid ett specifikt tillfälle och anpassa tröskeltemperaturen efter fronttypen. Simuleringar med det nyutvecklade modellsystemet för testområdet Kultsjön i Västerbotten visar att assimilering med EnKF av distribuerade snödata förbättrade vårflodsprognoserna samtliga 4 år i delområdet Kultsjön och 3 av 4 år i delområdet Ransarn. Den relativa förbättringen var i medel 10-15 % beroende på vilka drivdata som användes. Störst förbättring av vårflodsprognosen, jämfört med den traditionella metoden med ensembler av historiska år, erhölls emellertid genom att använda säsongsprognoser från ECMWF (European Centre for Medium Range Weather Forecasts) som drivdata. Det var överraskande att dessa simuleringar gav bättre resultat än simuleringar med stationsmätningar. En möjlig förklaring kan vara att den interpolation av stationsdata som ligger till grund för SMHIs operationella drivdata (nederbörd och temperatur, PTHBV) kan ge både över- och underskattning av nederbörd i fjällområden beroende på om vädersystemen kommer från väster eller öster. Medelvolymfelet för Kultsjön förbättrades från 17 % till 8 % för de undersökta åren när en kombination av säsongsprognoser från ECMWF och assimilering av snöradardata användes istället för en deterministisk PTHBV-simulering. Den utvecklade dataassimileringstekniken har således visats sig vara ett effektivt sätt att automatiskt uppdatera modellerna inför vårflodsprognosen, och bör enkelt kunna anpassas för operationell användning. Det är också tydligt att assimilering av väderprognosdata från ECWMF gav en bättre prognos för Kultsjöns avrinningsområde än nuvarande PTHBV data. Mer arbete med att förstå hur osäkerheter och korrelationer i såväl snödata som modelldata krävs dock för att med säkerhet slå fast att målsättningarna i projektet har uppnåtts. Användningen av väderprognosdata som input i kombination med assimilering av snödata var mycket lovande och bör vidareutvecklas.
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| 46. |
- Gustafsson Friberger, Marie, 1980-, et al.
(författare)
-
Collaboration processes, outcomes, challenges and enablers of distributed clinical communities of practice
- 2011
-
Ingår i: Behavior and Information Technology. - : Taylor & Francis. - 0144-929X .- 1362-3001. ; 32:6, s. 519-531
-
Tidskriftsartikel (refereegranskat)abstract
- Modern healthcare's need for knowledge sharing and bridging the research–practice gap requires new forms of collaboration, in which clinicians of varying clinical and research expertise work together over geographical and organisational borders. To support such distributed communities of practice (CoPs), an understanding of their collaboration processes, outcomes, challenges and enablers is needed. The article examines these issues through a case study of a long-running CoP, the Swedish Oral Medicine Network (SOMNet). SOMNet's main form of collaboration is monthly telephone conference meetings centred on case consultations. Cases are submitted by the clinicians via a Web-based system. The methods used were interviews, observations, and a questionnaire. The work adds to previous research by studying a distributed CoP explicitly focused on supporting the transfer of scientific results from researchers to practitioners. We found that the regular meetings give a rhythm to the community. The centrality of cases means an immediate benefit for the submitter while the community is provided an authentic context for learning. SOMNet yields opportunities for help and learning for diverse expertise levels; the type of benefits is affected by the participant's degree of oral medicine knowledge and collaboration involvement. There are challenges in accommodating varying levels of expertise and encouraging those less experienced to participate. Enablers of the collaboration include the participation of experts, meeting facilitators and well-adapted ITs.
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| 47. |
- Gustafsson, Göran, 1955, et al.
(författare)
-
A National Academic-Industrial Research Program with an Integrated Graduate Research School
- 2013
-
Ingår i: Lecture Notes in Mechanical Engineering: 4th International Conference on Research into Design, ICoRD'13. Global Product Development, Indian Institute of Technology Madras, Chennai, Tamil Nadu, India, 7-9 January 2013. - India : Springer India. - 2195-4356. - 9788132210504 ; , s. 1117-1127
-
Konferensbidrag (refereegranskat)abstract
- ProViking is a successful Swedish twelve-year research program in product development and production. Rather than to stimulate the emergence of new companies, it aims at strengthening the existing Swedish industry by producing scientific results at the highest international level and Ph.D.’s for work in the industry. ProViking comprises a large number of research projects, jointly run by universities and industrial companies, and a national graduate school which provides courses for the Ph.D. students that work in the projects. The total ProViking budget is close to 110 M€, of which 43 M€ is supplied by the Swedish Foundation for Strategic Research and the rest by the industrial project partners. Since the program started in 2002, forty-one different research projects have so far resulted in several hundred conferences and journal papers. Some fifteen patents have either been granted or have applications pending as a result of the research, and almost one hundred Ph.D.’s have graduated.
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| 48. |
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| 49. |
- Gustafsson, Göran
(författare)
-
Society without God
- 2010
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Ingår i: Nordic Journal of Religion and Society. - 0809-7291. ; 23:2, s. 214-217
-
Recension (övrigt vetenskapligt/konstnärligt)
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| 50. |
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