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Träfflista för sökning "WFRF:(HERSKIND B) srt2:(2020-2021)"

Sökning: WFRF:(HERSKIND B) > (2020-2021)

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1.
  • Basu, Anwesha, et al. (författare)
  • Highly deformed band structures due to core excitations in Xe 123
  • 2021
  • Ingår i: Physical Review C. - 2469-9985. ; 103:1
  • Tidskriftsartikel (refereegranskat)abstract
    • High-spin states in Xe123 were populated in the Se80(Ca48, 5n)Xe123 reaction at a beam energy of 207 MeV. γ-ray coincidence events were recorded with the Gammasphere spectrometer. Four new high-spin bands have been discovered in this nucleus. The bands are compared with those calculated within the framework of cranked Nilsson-Strutinsky and cranked Nilsson-Strutinsky-Bogoliubov models. It is concluded that the configurations of the bands involve two-proton excitations across the Z=50 as well as excitation of neutrons across the N=82 shell gaps resulting in a large deformation, 2≈0.30 and γ≈5°C.
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2.
  • Basu, Anwesha, et al. (författare)
  • Evolution of collective and noncollective structures in Xe 123
  • 2020
  • Ingår i: Physical Review C. - 2469-9985. ; 101:2
  • Tidskriftsartikel (refereegranskat)abstract
    • An experiment involving a heavy-ion-induced fusion-evaporation reaction was carried out where high-spin states of Xe123 were populated in the Se80(Ca48,5n)Xe123 reaction at 207 MeV beam energy. Gamma-ray coincidence events were recorded with the Gammasphere Ge detector array. The previously known level scheme was confirmed and enhanced with the addition of five new band structures and several interband transitions. Cranked Nilsson-Strutinsky (CNS) calculations were performed and compared with the experimental results in order to assign configurations to the bands.
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3.
  • Abramson, Alex, et al. (författare)
  • Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors
  • 2021
  • Ingår i: Nature Biotechnology. - : Springer Nature. - 1087-0156 .- 1546-1696. ; 40:1, s. 103-109
  • Tidskriftsartikel (refereegranskat)abstract
    • Oral administration provides a simple and non-invasive approach for drug delivery. However, due to poor absorption and swift enzymatic degradation in the gastrointestinal tract, a wide range of molecules must be parenterally injected to attain required doses and pharmacokinetics. Here we present an orally dosed liquid auto-injector capable of delivering up to 4-mg doses of a bioavailable drug with the rapid pharmacokinetics of an injection, reaching an absolute bioavailability of up to 80% and a maximum plasma drug concentration within 30 min after dosing. This approach improves dosing efficiencies and pharmacokinetics an order of magnitude over our previously designed injector capsules and up to two orders of magnitude over clinically available and preclinical chemical permeation enhancement technologies. We administered the capsules to swine for delivery of clinically relevant doses of four commonly injected medications, including adalimumab, a GLP-1 analog, recombinant human insulin and epinephrine. These multi-day dosing experiments and oral administration in awake animal models support the translational potential of the system. 
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  • Resultat 1-3 av 3

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