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Träfflista för sökning "WFRF:(Herbert A) srt2:(2000-2004)"

Sökning: WFRF:(Herbert A) > (2000-2004)

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  • Frisk, U., et al. (författare)
  • The Odin satellite - I. Radiometer design and test
  • 2003
  • Ingår i: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 402:3, s. L27-L34
  • Tidskriftsartikel (refereegranskat)abstract
    • The Sub-millimetre and Millimetre Radiometer (SMR) is the main instrument on the Swedish, Canadian, Finnish and French spacecraft Odin. It consists of a 1.1 metre diameter telescope with four tuneable heterodyne receivers covering the ranges 486-504 GHz and 541-581 GHz, and one fixed at 118.75 GHz together with backends that provide spectral resolution from 150 kHz to 1 MHz. This Letter describes the Odin radiometer, its operation and performance with the data processing and calibration described in Paper II.
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  • Herbert, Roger B, et al. (författare)
  • Granular iron reactive barriers for the degradation of chlorinated solvents in groundwater
  • 2000
  • Ingår i: Vatten. - 0042-2886. ; 56:4, s. 261-266
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper presents the results of batch and column experiments that investigated the degradation of chlorinated solvents bv zerovalent granular iron. These experiments were designed to produce data essential for the installation of a field-scale permeable reactive barrier at a field site with groundwater contaminated bv perchloroethylene (PCE) and other less chlorinated ethenes. The batch tests were conducted in order to identify a suitable iron product for the reactive matrix in a barrier. The test results indicated that an American iron product, because of its greater surface area, was superior in the degradation of PCE relative to other selected granular iron products. The column experiments were designed to determine the rates of PCE, TCE and cis-DCE removal and the column residence times needed to achieve solvent degradation. For a column composed of a mixture of 50% granular iron and 50% sand, the results showed that the time for a 50 % decrease (t50) in solvent concentration was < 1.3 hours for PCE, ca. 1.4 hours for TCE, and ca. 1.9 hours for cis-DCE. These results can be used to dimension a field-scale reactive barrier, where the groundwater residence time must be in excess of these t50 values.
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  • Sandström, Herbert, et al. (författare)
  • Congenital dyserythropoietic anemia type III.
  • 2000
  • Ingår i: Haematologica. - 0390-6078 .- 1592-8721. ; 85:7, s. 753-7
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND AND OBJECTIVES: Congenital dyserythropoietic anemia type III (CDA-III) is a group of very rare disorders characterized by similar bone marrow morphology. The clinical picture is characterized by hemolytic anemia and dramatic bone marrow changes dominated by active erythropoiesis with big multinucleated erythroblasts. The aim of this review is to describe the clinical manifestations, laboratory findings, and management CDA-III.EVIDENCE AND INFORMATION SOURCES: The present review critically examines relevant articles and abstracts published in journals covered by the Science Citation Index and Medline. The authors have performed several studies on CDA-III.STATE OF ART AND PERSPECTIVES: The clinical and laboratory manifestations of CDA-III indicate that the gene responsible for it, which has been mapped to chromosome 15q22, is expressed not only in erythroblasts during mitosis but also in B-cells, and in cells of the retina. Preliminary results indicate genetic and phenotypic similarities between a Swedish and an American family, both with an autosomally dominant inherited form of CDA-III. It is possible that the genetic lesion is identical in these families, but the different phenotypes and modes of inheritance reported among some other cases of CDA-III are probably the results of other genetic lesions. At present, the function of the gene responsible for the Swedish (V sterbotten) variant of CDA-III (CDAN3) is unknown and it is an important goal to characterize and clone this gene in order to study its function.
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  • Zdebska, E, et al. (författare)
  • Glycoconjugate abnormalities in patients with congenital dyserythropoietic anaemia type I, II and III.
  • 2001
  • Ingår i: British Journal of Haematology. - 0007-1048 .- 1365-2141. ; 114:4, s. 907-13
  • Tidskriftsartikel (refereegranskat)abstract
    • Congenital dyserythropoietic anaemia type II (CDA II) is well known for glycosylation abnormalities affecting erythrocyte membrane glycoconjugates that encompass hypoglycosylation of band 3 glycoprotein and accumulation of glycosphingolipids: lactotriaosylceramides, neolactotriaosylceramide and polyglycosylceramides. These abnormalities were not observed in erythrocytes from patients with CDA of either type I or III. Recently, however, we have described a CDA type I patient in Poland with identical, though less pronounced, glycoconjugate abnormalities to those observed in patients with CDA type II. The abnormalities included partial unglycosylation of O-linked glycosylation sites in glycophorin A. These abnormalities are now reported in three Bedouin patients from Israel with CDA type I. In addition, the erythrocyte membranes of these patients exhibited highly increased globotetraosylceramide content. Glycoconjugate abnormalities were also present in erythrocyte membranes from three patients from Northern Sweden with CDA type III but they almost exclusively affected glycosphingolipids. In erythrocytes of all patients examined including one with CDA type II, polyglycosylceramides were significantly hypoglycosylated although, on a molar basis, their contents in erythrocyte membranes were increased. Thus, glycoconjugate abnormalities of varying intensity occur in erythrocyte membranes from all patients with CDA that were investigated.
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