SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Hofer Peter) srt2:(2010-2014)"

Sökning: WFRF:(Hofer Peter) > (2010-2014)

  • Resultat 1-3 av 3
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Parsa, Afshin, et al. (författare)
  • Common Variants in Mendelian Kidney Disease Genes and Their Association with Renal Function
  • 2013
  • Ingår i: Journal of the American Society of Nephrology. - 1046-6673 .- 1533-3450. ; 24:12, s. 2105-2117
  • Tidskriftsartikel (refereegranskat)abstract
    • Many common genetic variants identified by genome-wide association studies for complex traits map to genes previously linked to rare inherited Mendelian disorders. A systematic analysis of common single-nucleotide polymorphisms (SNPs) in genes responsible for Mendelian diseases with kidney phenotypes has not been performed. We thus developed a comprehensive database of genes for Mendelian kidney conditions and evaluated the association between common genetic variants within these genes and kidney function in the general population. Using the Online Mendelian Inheritance in Man database, we identified 731 unique disease entries related to specific renal search terms and confirmed a kidney phenotype in 218 of these entries, corresponding to mutations in 258 genes. We interrogated common SNPs (minor allele frequency >5%) within these genes for association with the estimated GFR in 74,354 European-ancestry participants from the CKDGen Consortium. However, the top four candidate SNPs (rs6433115 at LRP2, rs1050700 at TSC1, rs249942 at PALB2, and rs9827843 at ROBO2) did not achieve significance in a stage 2 meta-analysis performed in 56,246 additional independent individuals, indicating that these common SNPs are not associated with estimated GFR. The effect of less common or rare variants in these genes on kidney function in the general population and disease-specific cohorts requires further research.
  •  
2.
  • Lundmark, Tomas, et al. (författare)
  • Potential Roles of Swedish Forestry in the Context of Climate Change Mitigation
  • 2014
  • Ingår i: Forests. - Basel, Switzerland : MDPI AG. - 1999-4907. ; 5:4, s. 557-578
  • Tidskriftsartikel (refereegranskat)abstract
    • In Sweden, where forests cover more than 60% of the land area, silviculture and the use of forest products by industry and society play crucial roles in the national carbon balance. A scientific challenge is to understand how different forest management and wood use strategies can best contribute to climate change mitigation benefits. This study uses a set of models to analyze the effects of different forest management and wood use strategies in Sweden on carbon dioxide emissions and removals through 2105. If the present Swedish forest use strategy is continued, the long-term climate change mitigation benefit will correspond to more than 60 million tons of avoided or reduced emissions of carbon dioxide annually, compared to a scenario with similar consumption patterns in society but where non-renewable products are used instead of forest-based products. On average about 470 kg of carbon dioxide emissions are avoided for each cubic meter of biomass harvested, after accounting for carbon stock changes, substitution effects and all emissions related to forest management and industrial processes. Due to Sweden’s large export share of forest-based products, the climate change mitigation effect of Swedish forestry is larger abroad than within the country. The study also shows that silvicultural methods to increase forest biomass production can further reduce net carbon dioxide emissions by an additional 40 million tons of per year. Forestry’s contribution to climate change mitigation could be significantly increased if management of the boreal forest were oriented towards increased biomass production and if more wood were used to substitute fossil fuels and energy-intensive materials.
  •  
3.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-3 av 3
Typ av publikation
tidskriftsartikel (3)
Typ av innehåll
refereegranskat (3)
Författare/redaktör
Deshmukh, Harshal (1)
Samuelsson, Lena, 19 ... (1)
Viikari, Jorma (1)
Portas, Laura (1)
Imboden, Medea (1)
Minelli, Cosetta (1)
visa fler...
Probst-Hensch, Nicol ... (1)
Kere, Juha (1)
Adam, Martin (1)
Torinsson Naluai, Ås ... (1)
Estivill, Xavier (1)
Campbell, Harry (1)
Rudan, Igor (1)
Deloukas, Panos (1)
Freedman, Barry I. (1)
Perricone, Carlo (1)
Nordin, Annika (1)
Johansson, Åsa (1)
Ridker, Paul M. (1)
Chasman, Daniel I. (1)
Demirkan, Ayse (1)
van Duijn, Cornelia ... (1)
Chu, Audrey Y (1)
Shuldiner, Alan R. (1)
Weale, Michael E. (1)
Bergh, Johan (1)
Lundmark, Tomas (1)
Oostra, Ben A. (1)
Wichmann, H. Erich (1)
Peltonen, Leena (1)
Worthington, Jane (1)
Gyllensten, Ulf (1)
Metspalu, Andres (1)
Palmer, Colin N. A. (1)
Zaboli, Ghazal (1)
Igl, Wilmar (1)
Pramstaller, Peter P ... (1)
Wright, Alan F. (1)
Wilson, James F. (1)
de Andrade, Mariza (1)
Schmidt, Reinhold (1)
Schmidt, Helena (1)
Kovacs, Peter (1)
Giardina, Emiliano (1)
McManus, Ross (1)
Ryan, Anthony W. (1)
Traupe, Heiko (1)
FitzGerald, Oliver (1)
Novelli, Giuseppe (1)
Barton, Anne (1)
visa färre...
Lärosäte
Göteborgs universitet (1)
Uppsala universitet (1)
Mittuniversitetet (1)
Linnéuniversitetet (1)
Karolinska Institutet (1)
Sveriges Lantbruksuniversitet (1)
Språk
Engelska (3)
Forskningsämne (UKÄ/SCB)
Teknik (1)
Medicin och hälsovetenskap (1)
Lantbruksvetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy