1. |
|
|
2. |
- Hopewell, JW, et al.
(author)
-
Boron neutron capture therapy for newly diagnosed glioblastoma multiforme: An assessment of clinical potential
- 2011
-
In: APPLIED RADIATION AND ISOTOPES. - 0969-8043. ; 69:12, s. 1737-1740
-
Journal article (peer-reviewed)abstract
- Abstract: The purpose of this analysis was to assess the potential of BNCT, with L-boronophenylalanine (L-BPA), as first line radiotherapy for glioblastoma multiforme (GBM). The survival of patients with newly diagnosed GBM from a phase II BNCT study was compared with those from the two arms of a phase Ill study with conventional radiotherapy (RT) vs. RT plus concomitant and adjuvant medication with temozolomide (TMZ). A small subgroup, for which the methylation status of the O(6)-methylguanine-DNA methyltransferase (MGMT) DNA-repair gene was known, was also considered. The results indicated that the use of BNCT with BPA should be explored in a stratified randomized phase II trial in which patients with the unmethylated MGMT DNA-repair gene are offered BNCT vs. RT plus TMZ. (C) 2011 Elsevier Ltd. All rights reserved.
|
|
3. |
- Laissue, JA, et al.
(author)
-
Response of the rat spinal cord to X-ray microbeams
- 2013
-
In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. - : Elsevier BV. - 1879-0887. ; 106:1, s. 106-111
-
Journal article (peer-reviewed)
|
|
4. |
|
|
5. |
|
|