| 1. |
- Fawole, H. O., et al.
(författare)
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Is the association between physical activity and fatigue mediated by physical function or depressive symptoms in symptomatic knee osteoarthritis? The Multicenter Osteoarthritis Study
- 2021
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Ingår i: Scandinavian Journal of Rheumatology. - : Informa UK Limited. - 0300-9742 .- 1502-7732. ; 50:5, s. 372-380
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: To examine whether physical activity (PA) was associated with fatigue, and quantify the extent of potential mediation through depressive symptoms or physical function (PF) on the relationship between PA and fatigue in symptomatic knee osteoarthritis (KOA). Method: This longitudinal study used data from the Multicenter Osteoarthritis Study (n = 484), comprising subjects aged ≥ 50 years. Baseline PA was quantified via an ankle-worn accelerometer. The outcome was fatigue, measured using a 0–10 rating scale at 2 year follow-up. Mediators included gait speed as a measure of PF and depressive symptoms at 2 year follow-up. Mediation analysis was carried out after adjustment for baseline confounders. Stratified analysis by baseline fatigue status [no/low (< 4) and high (≥ 4) fatigue] was performed. Results: A significant direct association was found between PA and fatigue at 2 years [unstandardized coefficient (B) = −0.054; 95% confidence interval (CI) −0.107, −0.002, p = 0.041]. The PA–fatigue relationship was not mediated by gait speed (B = −0.006; 95% CI −0.018, 0.001) or depressive symptoms (B = 0.009; 95% CI 0.009, 0.028). In the subgroup with high baseline fatigue, direct associations were found between PA and fatigue (gait speed model:, B = −0.107; 95% CI −0.212, −0.002, p = 0.046; depressive symptoms model: B = −0.110; 95% CI −0.120, −0.020, p = 0.017); but in the no/low baseline fatigue group, no significant association was found between PA and fatigue. Conclusion: In the symptomatic KOA population, higher baseline PA was directly associated with reduced fatigue 2 years later, especially in those with high baseline fatigue. However, this relationship was not mediated by depressive symptoms or PF.
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| 2. |
- Chintzoglou, Georgios, et al.
(författare)
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ALMA and IRIS Observations of the Solar Chromosphere. I. An On-disk Type II Spicule
- 2021
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 906:2
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Tidskriftsartikel (refereegranskat)abstract
- We present observations of the solar chromosphere obtained simultaneously with the Atacama Large Millimeter/submillimeter Array (ALMA) and the Interface Region Imaging Spectrograph. The observatories targeted a chromospheric plage region of which the spatial distribution (split between strongly and weakly magnetized regions) allowed the study of linear-like structures in isolation, free of contamination from background emission. Using these observations in conjunction with a radiative magnetohydrodynamic 2.5D model covering the upper convection zone all the way to the corona that considers nonequilibrium ionization effects, we report the detection of an on-disk chromospheric spicule with ALMA and confirm its multithermal nature.
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| 3. |
- Chintzoglou, Georgios, et al.
(författare)
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ALMA and IRIS Observations of the Solar Chromosphere. II. Structure and Dynamics of Chromospheric Plages
- 2021
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 906:2
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Tidskriftsartikel (refereegranskat)abstract
- We propose and employ a novel empirical method for determining chromospheric plage regions, which seems to better isolate a plage from its surrounding regions than other methods commonly used. We caution that isolating a plage from its immediate surroundings must be done with care in order to successfully mitigate statistical biases that, for instance, can impact quantitative comparisons between different chromospheric observables. Using this methodology, our analysis suggests that lambda = 1.25 mm free-free emission in plage regions observed with the Atacama Large Millimeter/submillimeter Array (ALMA)/Band6 may not form in the low chromosphere as previously thought, but rather in the upper chromospheric parts of dynamic plage features (such as spicules and other bright structures), i.e., near geometric heights of transition-region temperatures. We investigate the high degree of similarity between chromospheric plage features observed in ALMA/Band6 (at 1.25 mm wavelengths) and the Interface Region Imaging Spectrograph (IRIS)/Si iv at 1393 angstrom. We also show that IRIS/Mg ii h and k are not as well correlated with ALMA/Band6 as was previously thought, and we discuss discrepancies with previous works. Lastly, we report indications of chromospheric heating due to propagating shocks supported by the ALMA/Band6 observations.
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