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Träfflista för sökning "WFRF:(Jakob André) srt2:(2015-2019)"

Sökning: WFRF:(Jakob André) > (2015-2019)

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1.
  • Alessandro, B., et al. (författare)
  • Vector boson scattering : Recent experimental and theory developments
  • 2018
  • Ingår i: Reviews in Physics. - : Elsevier BV. - 2405-4283. ; 3, s. 44-63
  • Tidskriftsartikel (refereegranskat)abstract
    • This document summarises the talks and discussions happened during the VBSCan Split17 workshop, the first general meeting of the VBSCan COST Action network. This collaboration is aiming at a consistent and coordinated study of vector-boson scattering from the phenomenological and experimental point of view, for the best exploitation of the data that will be delivered by existing and future particle colliders. 
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2.
  • Bentham, James, et al. (författare)
  • A century of trends in adult human height
  • 2016
  • Ingår i: eLIFE. - 2050-084X. ; 5
  • Tidskriftsartikel (refereegranskat)abstract
    • Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.522.7) and 16.5 cm (13.319.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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3.
  • Bentham, James, et al. (författare)
  • A century of trends in adult human height
  • 2016
  • Ingår i: eLIFE. - : eLife Sciences Publications Ltd. - 2050-084X. ; 5
  • Tidskriftsartikel (refereegranskat)abstract
    • Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3– 19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8– 144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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5.
  • Barth, Julia M.I., et al. (författare)
  • Genome architecture enables local adaptation of Atlantic cod despite high connectivity
  • 2017
  • Ingår i: Molecular Ecology. - : Wiley. - 0962-1083 .- 1365-294X. ; 26:17, s. 4452-4466
  • Tidskriftsartikel (refereegranskat)abstract
    • Adaptation to local conditions is a fundamental process in evolution; however, mechanisms maintaining local adaptation despite high gene flow are still poorly understood. Marine ecosystems provide a wide array of diverse habitats that frequently promote ecological adaptation even in species characterized by strong levels of gene flow. As one example, populations of the marine fish Atlantic cod (Gadus morhua) are highly connected due to immense dispersal capabilities but nevertheless show local adaptation in several key traits. By combining population genomic analyses based on 12K single nucleotide polymorphisms with larval dispersal patterns inferred using a biophysical ocean model, we show that Atlantic cod individuals residing in sheltered estuarine habitats of Scandinavian fjords mainly belong to offshore oceanic populations with considerable connectivity between these diverse ecosystems. Nevertheless, we also find evidence for discrete fjord populations that are genetically differentiated from offshore populations, indicative of local adaptation, the degree of which appears to be influenced by connectivity. Analyses of the genomic architecture reveal a significant overrepresentation of a large ~5 Mb chromosomal rearrangement in fjord cod, previously proposed to comprise genes critical for the survival at low salinities. This suggests that despite considerable connectivity with offshore populations, local adaptation to fjord environments may be enabled by suppression of recombination in the rearranged region. Our study provides new insights into the potential of local adaptation in high gene flow species within fine geographical scales and highlights the importance of genome architecture in analyses of ecological adaptation.
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6.
  • Lundkvist, André, et al. (författare)
  • 3D Auditory Displays for Parking Assistance Systems
  • 2017
  • Ingår i: SAE International Journal of Passenger Cars - Electronic and Electrical Systems. - : Society of Automotive Engineers. - 1946-4614 .- 1946-4622. ; 10:1, s. 17-23
  • Tidskriftsartikel (refereegranskat)abstract
    • The objective of this study was to investigate if 3D auditory displays could be used to enhance parking assistance systems (PAS). Objective measurements and estimations of workload were used to assess the benefits of different 3D auditory displays. In today’s cars, PAS normally use a visual display together with simple sound signals to inform drivers of obstacles in close proximity. These systems rely heavily on the visual display, as the sound does not provide information about obstacles' location. This may cause the driver to lose focus on the surroundings and reduce situational awareness. Two user studies (during summer and winter) were conducted to compare three different systems. The baseline system corresponded to a system normally found in today’s cars. The other systems were designed with a 3D auditory display, conveying information of where obstacles were located through sound. A visual display was also available. Both normal parking and parallel parking was conducted. Time taken for parking and the number of obstacles/curb hits were recorded. Participants answered a NASA TLX questionnaire after evaluating each PAS for estimation of their experienced workload. Most participants enjoyed the additional information provided by the 3D auditory displays. The winter trial showed a significant reduction in perceived effort when using a 3D auditory display compared to the baseline. The summer trial showed tendencies of higher mental demand and frustration with the baseline compared to the 3D auditory displays. The results suggest that 3D auditory displays can be appreciated and useful in difficult parking situations.
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7.
  • Raudberget, Dag, 1967, et al. (författare)
  • Supporting design platforms by identifying flexible modules
  • 2017
  • Ingår i: Proceedings of the International Conference on Engineering Design, ICED. - : The Design Society. - 2220-4334 .- 2220-4342. ; 3:DS87-3, s. 191-200, s. 191-200
  • Konferensbidrag (refereegranskat)abstract
    • One way for firms to stay competitive is to adapt a platform approach. In product platforms, modules are used as exchangeable design blocks to create a variety in product performance. This is a proven way to get advantages of scale in production by reusing physical parts and investments in manufacturing. To ensure exchangeability between modules, interfaces between modules must be well defined. Hence, from this point of view, there is no such thing as flexible modules. In this research, flexibility refers to the idea of identifying strategic portions of the platform where flexibility is needed and to create the modular division in a way that the assigned modules are de-coupled in theses areas. The presented approach shows how the Design platform concept can be extended by the introduction of flexible modules. These support the Design Platforms by allowing areas of strategic importance to be more flexible and thereby enable room for uncertainties such as fluctuating requirements and future technical development.
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8.
  • van der Valk, Ralf J P, et al. (författare)
  • A novel common variant in DCST2 is associated with length in early life and height in adulthood.
  • 2015
  • Ingår i: Human molecular genetics. - : Oxford University Press (OUP). - 1460-2083 .- 0964-6906. ; 24:4, s. 1155-68
  • Tidskriftsartikel (refereegranskat)abstract
    • Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide association studies (Stage 1; N = 28 459). We identified seven independent top single nucleotide polymorphisms (SNPs) (P < 1 × 10(-6)) for birth length, of which three were novel and four were in or near loci known to be associated with adult height (LCORL, PTCH1, GPR126 and HMGA2). The three novel SNPs were followed-up in nine replication studies (Stage 2; N = 11 995), with rs905938 in DC-STAMP domain containing 2 (DCST2) genome-wide significantly associated with birth length in a joint analysis (Stages 1 + 2; β = 0.046, SE = 0.008, P = 2.46 × 10(-8), explained variance = 0.05%). Rs905938 was also associated with infant length (N = 28 228; P = 5.54 × 10(-4)) and adult height (N = 127 513; P = 1.45 × 10(-5)). DCST2 is a DC-STAMP-like protein family member and DC-STAMP is an osteoclast cell-fusion regulator. Polygenic scores based on 180 SNPs previously associated with human adult stature explained 0.13% of variance in birth length. The same SNPs explained 2.95% of the variance of infant length. Of the 180 known adult height loci, 11 were genome-wide significantly associated with infant length (SF3B4, LCORL, SPAG17, C6orf173, PTCH1, GDF5, ZNFX1, HHIP, ACAN, HLA locus and HMGA2). This study highlights that common variation in DCST2 influences variation in early growth and adult height.
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