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- Cámara, Fernando, 1967-, et al.
(författare)
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Zinkgruvanite, Ba4Mn2+4Fe3+2(Si2O7)2(SO4)2O2(OH)2, a new ericssonite-group mineral from the Zinkgruvan Zn-Pb-Ag-Cu deposit, Askersund, Örebro County, Sweden.
- 2021
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Ingår i: European journal of mineralogy. - : Nicolaus Copernicus University Press. - 0935-1221 .- 1617-4011. ; 33:6, s. 659-673
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Tidskriftsartikel (refereegranskat)abstract
- Zinkgruvanite, ideally Ba4Mn2+4Fe3+2(Si2O7)2(SO4)2O2(OH)2, is a new member of the ericssonite group, found in Ba-rich drill core samples from a sphalerite+galena- and diopside-rich metatuffite succession from the Zinkgruvan mine, Örebro county, Sweden. Zinkgruvanite is associated with massive baryte, barytocalcite, diopside and minor witherite, cerchiaraite-(Al) and sulfide minerals. It occurs as subhedral to euhedral flattened and elongated crystals up to 4 mm. It is almost black, semi-opaque with a dark brown streak. The luster is vitreous to sub-adamantine on crystal faces, resinous on fractures. The mineral is brittle with an uneven fracture. VHN100 = 539 and HMohs ~4½. In thin fragments, it is reddish-black, translucent and optically biaxial (+), 2Vz > 70°. Pleochroism is strong, deep brown-red (E ⊥ {001} cleavage) to olive-pale brown. Chemical point analyses by WDS-EPMA together with iron valencies determined from Mössbauer spectroscopy, yielded the empirical formula (based on 26 O+OH+F+Cl anions): (Ba4.02Na0.03)Σ4.05(Mn1.79Fe2+1.56Fe3+0.42Mg0.14Ca0.10Ni0.01Zn0.01)Σ4.03 (Fe3+1.74Ti0.20Al0.06)Σ2.00Si4(S1.61Si0.32P0.07)Σ1.99O24(OH1.63Cl0.29F0.08)Σ2.00. The mineral is triclinic, space group P–1, with unit-cell parameters a = 5.3982(1) Å, b = 7.0237(1) Å, c = 14.8108(4) Å, α = 98.256(2)º, β = 93.379(2)º, γ = 89.985(2)º and V = 554.75(2) Å3 for Z = 1. The eight strongest X-ray powder diffraction lines are [d Å (I%; hkl)]: 3.508 (70; 103), 2.980(70; 11–4), 2.814 (68; 1–22), 2.777 (70; 121), 2.699 (714; 200), 2.680 (68; 20–1), 2.125 (100; 124, 204), 2.107 (96; –221). The crystal structure (R1 = 0.0379 for 3204 reflections) is an array of TS (titanium silicate) blocks alternating with intermediate blocks. The TS blocks consist of HOH sheets (H = heteropolyhedral, O = octahedral) parallel to (001). In the O sheet, the Mn2+-dominant MO(1,2,3) sites give ideally Mn2+4 pfu. In the H sheet, the Fe3+-dominant MH sites and AP(1) sites give ideally Fe3+2Ba2 pfu. In the intermediate block, SO4 oxyanions and eleven coordinated Ba atoms give ideally 2 × SO4Ba pfu. Zinkgruvanite is related to ericssonite and ferro-ericssonite in having the same topology and type of linkage of layers in the TS block. Zinkgruvanite is also closely compositionally related to yoshimuraite, Ba4Mn4Ti2(Si2O7)2(PO4)2O2(OH)2, via the coupled heterovalent substitution 2 Ti4+ + 2 (PO4)3- →2 Fe3+ + 2 (SO4)2-, but presents a different type of linkage. The new mineral probably formed during a late stage of regional metamorphism of a Ba-enriched, syngenetic protolith, involving locally generated oxidized fluids of high salinity.
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| 2. |
- Jansson, Jörgen, et al.
(författare)
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Advanced paramedics and nurses can deliver safe and effective pre-hospital and in-hospital emergency care : An integrative review
- 2021
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Ingår i: Nursing Open. - : Wiley-Blackwell. - 2054-1058. ; 8:5, s. 2385-2405
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Tidskriftsartikel (refereegranskat)abstract
- Aim To explore and present an overview of scope of practice among registered nurses and paramedics with an advanced level of education in pre-hospital and in-hospital emergency care. Design An integrative literature review. Method Studies published between 2006 and 2018 were retrieved by searching the databases CINAHL, PubMed, Scopus and Web of Science. Studies were selected by three independent researchers, and data were synthesized using thematic analysis. Results The 25 studies identified focused on in-hospital (n = 15) and pre-hospital emergency care (n = 10) and included 13 professional titles originated from seven countries. The thematic analysis disclosed four themes; "Versatile care," "Safe care based on precision and accuracy," "Autonomous performance within boundaries" and "Beneficial towards patients and society." Advanced paramedics' and advanced nurses' services are characterized as safe, of high quality and of public benefit. Their services are being used in everyday practice as well as directed to certain categories of patients.
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| 5. |
- Jansson, Jörgen, et al.
(författare)
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Prehospital care nurses' self reported competence : A cross-sectional study
- 2020
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Ingår i: International Emergency Nursing. - : Elsevier. - 1755-599X .- 1878-013X. ; 52, s. 1-7
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Tidskriftsartikel (refereegranskat)abstract
- Background: The Swedish ambulance service has undergone major changes in recent decades due to advancements being made in medical and technical resources, professional competence, and patient care. Registered and specialist nurses share the same role, accountabilities, and responsibilities in the ambulance service, and their professional competence has not yet been evaluated. Objectives: The aim of the study was to investigate and compare self-reported professional competence among nurses working in the ambulance service and to explore associations between potentially predictive background factors and self-reported professional competence. Method: A cross-sectional study with a digital questionnaire was used for collecting data from 34 registered nurses and 71 specialist nurses. The Ambulance Nurse Competence Scale and the Research Utilization Questionnaire were used for data collection. Results: Significant differences were found among the nursing categories in terms of age, gender, education, and work experience. Prehospital emergency nurses reported the highest professional competence. Nurses with a master's degree did not report significantly higher professional competence than nurses with a bachelor's degree. Conclusions: The findings indicated that there are differences in the professional competence of registered nurses and specialist nurses. Length of work experience in the ambulance service is an important factor associated with higher professional competence.
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| 6. |
- Jansson, Jörgen
(författare)
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Prehospital nurses’ professional competence – utilization and development
- 2023
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The overall aim of this thesis was to explore nurses’ professional competence with a focus on scope of practice, content, utilization, and development within the ambulance service in Sweden.Methods: Integrative review (I), qualitative (II, III) and quantitative methods (IV) were used. The integrative review was based on 25 studies. The qualitative studies were based on interviews with 13 (II) and 16 prehospital nurses (III), and data was analyzed using content analysis (II) and grounded theory (III). In the quantitative study (IV), 105 nurses answered a digital questionnaire and descriptive and analytical statistics were used in the analysis. Main findings: Advanced nurses’ and paramedics’ assessments, treatments, and referrals were safe and of high quality and were characterized by a high degree of autonomy. Patients were satisfied with the care provided, reduced waiting times, and the avoidance of unnecessary transportation to hospital (I). Broad medical and nursing competence was required, and personality traits and contextual awareness were emphasized as unique competences (II). Prehospital emergency nurses reported higher levels of professional competence compared to registered nurses or other specialist nurses. No differences were identified between nurses with master’s or bachelor’s degrees, and clinical experience was a predictor of nursing competence (IV). At the start of their careers, the ambulance service represented a developing environment for nurses. When focus, education, roles, responsibilities, and requirements remained the same, continued competence development risked stagnation (III).Conclusions: Personality, clinical competence, prehospital experience, and contextual competence were emphasized. Academic competence was neglected and not demanded. This thesis provides new knowledge that can contribute to the continued development of the ambulance service and to a more efficient utilization of the full spectrum of nurses’ professional competence.
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| 7. |
- Karlsson Sundbaum, Johanna, et al.
(författare)
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Uncontrolled asthma predicts severe COVID-19: a report from the Swedish National Airway Register.
- 2022
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Ingår i: Therapeutic advances in respiratory disease. - : SAGE Publications. - 1753-4666 .- 1753-4658. ; 16
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Tidskriftsartikel (refereegranskat)abstract
- Severe asthma increases the risk of severe COVID-19 outcomes such as hospitalization and death. However, more studies are needed to understand the association between asthma and severe COVID-19.A cohort of 150,430 adult asthma patients were identified in the Swedish National Airway Register (SNAR) from 2013 to December 2020. Data on body mass index, smoking habits, lung function, and asthma control test (ACT) were obtained from SNAR, and uncontrolled asthma was defined as ACT ⩽19. Patients with severe COVID-19 were identified following hospitalization or in death certificates based on ICD-10 codes U07.1 and U07.2. The Swedish Prescribed Drug register was used to identify comorbidities and data from Statistics Sweden for educational level. Multivariate logistic regression analyses were used to estimate associations with severe COVID-19.Severe COVID-19 was identified in 1067 patients (0.7%). Older age (OR=1.04, 95% CI=1.03-1.04), male sex (1.42, 1.25-1.61), overweight (1.56, 1.27-1.91), obesity (2.12, 1.73-2.60), high-dose inhaled corticosteroids in combination with long-acting β-agonists (1.40, 1.22-1.60), dispensed oral corticosteroids ⩾2 (1.48, 1.25-1.75), uncontrolled asthma (1.64, 1.35-2.00), cardiovascular disease (1.20, 1.03-1.40), depression (1.47, 1.28-1.68), and diabetes (1.52, 1.29-1.78) were associated with severe COVID-19, while current smoking was inversely associated (0.63, 0.47-0.85). When comparing patients who died from COVID-19 with those discharged alive from hospital until 31 December 2020, older age, male sex, and current smoking were associated with COVID-19 death.Patients with uncontrolled asthma and high disease burden, including increased asthma medication intensity, should be identified as risk patients for severe COVID-19. Furthermore, current smoking is strongly associated with COVID-19 death in asthma.
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| 8. |
- Sidenblad, Anders, et al.
(författare)
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Desired prehospital competence in trauma care, a comparison of paramedic and prehospital emergency nurse students
- 2023
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- IntroductionHigh professional competence (Cheetham& Chivers, 1998) of personnel in ambulance services is something that patients, relatives, and the ambulance organizations themselves expect. Prehospital advanced trauma care requires high levels of professional and clinical competence, with high stakes decisions and judgements often being made with limited information or in less than ideal conditions (Wilson et al., 2015). The importance of trauma specific training is well established by the proliferation of trauma care education programs eg. BTLS, ATLS, PHTLS. The perceptions of prehospital providers regarding the competencies required to adequality care for trauma patients has been questioned ie. whether students learning is correctly focused on the competencies required in practice. It has been argued that student perceptions of self-efficacy and competence can positively influence learning, leading to greater effectiveness of competency based assessments (van Dinther et al., 2014).AimThe aim is to describe the perceptions of South African paramedic and Swedish prehospital emergency nurse students towards competence in prehospital trauma care and compare their alignment to the Global Rating Scale and Ambulance Nurse Competence Scale instruments commonly used for competency based assessments. MethodThe student will employ a cross sectional descriptive survey design with using an online questionnaire. Responses will be compared to validated instruments: the Global Rating Scale (Tavares et al, 2013) and the Ambulance Nurse Competence scale (Nilsson et al, 2022). The study populations consist of paramedic students from South Africa and prehospital emergency nurse students from Sweden. Analysis techniques will include descriptive and inferential methods. ResultThe results may indicate that the differences between paramedics and nurses are not substantial, but they may also reveal specific distinctions. Furthermore, it can provide a greater understanding of students' perspectives on competency in the prehospital field, which both education programs can benefit from in terms of curriculum and didactic growth.
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| 12. |
- Tabrizi, Fara, et al.
(författare)
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P117. Predicting Genetic Risk for Depression and Anxiety Disorders
- 2022
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Ingår i: Biological Psychiatry. - : Elsevier BV. - 0006-3223 .- 1873-2402. ; 91
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundPolygenic scores (PGSs) harness the potential to provide an overall measure of individuals’ genetic liability to develop a disease (Torkamani et al., 2018), though much research is still needed. The aim of the present study was to predict prescription of pharmacological treatment of anxiety or depression from PGSs.MethodsThe target sample comprised two cohorts of genotyped Swedish twins (n = 11037). Cases were defined as individuals prescribed pharmacological treatment of depression (n = 1129) or anxiety (n = 1446). We constructed 6 PGSs based on GWAS on MDD diagnosis, Anxiety, Schizophrenia, Neuroticism scores, the GAD-7 scale, and the PHQ-9. Data were analyzed by logistic regression models with change in pseudo-R2 (above the baseline model with sex, age, cohort, and 20 ancestral PCs) following the inclusion of PGSs to predict the risk of anxiety or depression medication. All results corrected for multiple comparisons.ResultsPredictive performance was estimated to ΔR2depression = 0.028; ΔR2anxiety = 0.025 when all PGSs were included in the same model, with PGS for MDD being the single best predictor for both anxiety and depression. Individuals in the top 10% of the PGS distribution had greater odds of drug prescription (ORdepression = 1.82; CI95% = 1.53—2.17; ORanxiety = 1.65; CI95% = 1.40—1.95), while the bottom 10% had decreased risk (ORanxiety = 0.56; CI95% = 0.45—0.70; ORdepression = 0.58; CI95% = 0.45—0.74) compared to the remaining 90% of the distribution.ConclusionsPGSs can predict drug prescription for anxiety and depression in an independent sample.
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| 13. |
- Tabrizi, Fara, et al.
(författare)
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Prediction of anxiety and depression from polygenic scores in Swedish twins
- 2021
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Ingår i: Abstracts of the WASAD Congress 2021. - : Springer. ; , s. 1802-1803
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Konferensbidrag (refereegranskat)abstract
- Recent genome-wide association studies (GWAS) have identified several common variants associated with depression (Howard et al. 2019; Levey et al. 2021) and anxiety disorders (Levey et al. 2020; Meier et al. 2019; Purves et al. 2020), and these findings have been harnessed to develop polygenic scores (PGS) in order to provide an overall measure of individuals’ genetic liability to develop a disease (Torkamani et al. 2018). Research on the utility of PGSs as predictors of risk for disease is gaining traction, with studies on somatic illness showing that disease risk increases sharply in the right tail of the PGS distribution (Khera et al. 2018). Thus, PGS stratification could be of clinical relevance if it provides an opportunity to target those in need of preventive interventions with increased precision. The current potential of PGS stratification for depression and anxiety disorders remains an open question. In the current study, we applied 36 predefined PGSs from the polygenic index repository (Becker et al. 2021) on a target sample of 11,210 genotyped twins. Cases were defined as those with prescribed medication, where the prescription explicitly stated that a drug was ordinated for indication of depression or anxiety, respectively. Drugs included antidepressants (SSRI and SNRI), Benzodiazepines, Antihistamines, Buspirone, and Betablockers.
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| 14. |
- Ögnelod, Tomas, et al.
(författare)
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Prehospital administration av blodprodukter vid trauma : Pilotstudie inför en scoping review
- 2023
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Prehospital användning av blodprodukter vid allvarliga trauman kan minska mortalitet och morbiditet. I olika länder och inom olika prehospitala system skiljer sig möjligheterna att administrera blodprodukter. Skillnaderna beror bland annat på resurser, personalens kompetens, risker, nytta samt varierande behov i olika miljöer.Syfte: Syftet med den preliminära litteraturöversikten var att studera prehospital administration av blodprodukter vid allvarliga trauman.Metod: Litteraturöversikt bedömdes som en lämplig metod för att samla kunskap om prehospital administrering av blodprodukter. Inklusionskriterier vid databassökningarna var att artiklar skulle ha prehospitalt fokus (militära och civila), omfatta administration av blodprodukter och traumatiska blödningar, vara publicerade år 2012 eller senare samt vara peer-reviewed. Litteraturöversikter exkluderades. Vid preliminära sökningar i databaser identifierades 509 unika artiklar.Resultat: Resultatet baserades på 10 artiklar från fem länder och omfattade militär och civil kontext. Artiklarna beskriver olika typer av allvarliga trauman där blodprodukter använts. Indikationer för att ge prehospitala blodprodukter var: påverkade vitalparametrar enskilt (n=8) eller kombinerat med bedömning av trauma (n=3), transporttid (n=1), shock index (n=1), laktat (n=1) eller ISS-score (n=1). Att ge blodprodukter prehospitalt var associerat med högre överlevnad men överlevnaden var också beroende av det prehospitala omhändertagandet, tidsfaktorer, typ av trauma och resurser. Konklusion: Prehospital administration av blodprodukter vid allvarliga trauman har potential att öka överlevnaden hos patienter. Genom en systematiskt genomförd litteraturöversikt kan tydligare kunskap framkomma. Argument för och emot prehospital användning av blodprodukter kan tydliggöras och litteraturöversikten kan bidra med underlag som tar hänsyn till alternativ, risker, nytta, kostnader, kompetens och tidsfaktorer för ambulansorganisationer som överväger att införa blodprodukter.
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