| 1. |
- de Peppo, Giuseppe Maria, 1981, et al.
(författare)
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Osteogenic response of human mesenchymal stem cells to well-defined nanoscale topography in vitro
- 2014
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Ingår i: International journal of nanomedicine. - : Informa UK Limited. - 1176-9114 .- 1178-2013. ; 9:1, s. 2499-2515
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Tidskriftsartikel (refereegranskat)abstract
- Background: Patterning medical devices at the nanoscale level enables the manipulation of cell behavior and tissue regeneration, with topographic features recognized as playing a significant role in the osseointegration of implantable devices. Methods: In this study, we assessed the ability of titanium-coated hemisphere-like topographic nanostructures of different sizes (approximately 50, 100, and 200 nm) to influence the morphology, proliferation, and osteogenic differentiation of human mesenchymal stem cells (hMSCs). Results: We found that the proliferation and osteogenic differentiation of hMSCs was influenced by the size of the underlying structures, suggesting that size variations in topographic features at the nanoscale level, independently of chemistry, can be exploited to control hMSC behavior in a size-dependent fashion. Conclusion: Our studies demonstrate that colloidal lithography, in combination with coating technologies, can be exploited to investigate the cell response to well defined nanoscale topography and to develop next-generation surfaces that guide tissue regeneration and promote implant integration.
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| 2. |
- Hedenus, Fredrik, 1976, et al.
(författare)
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Future food consumption and climate change - are dietary shifts required?
- 2010
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Ingår i: Stockholm Futures Conference. Our future in the making.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The FAO predicts a major increase in global animal food consumption to 2050. In this paper we investigate the climate effect of such a dietary shift. At present, food is responsible for 25-30% of the global greenhouse gas emissions. In contrast to the energy sector, the main way to reduce greenhouse gas emissions from food production seems to be through general productivity improvements, rather than from specific technological and agronomic mitigation measures. In this paper we estimate the resulting methane and nitrous oxide emissions from global agriculture in 2050, in two scenarios, one with moderate productivity improvement and one with rapid productivity improvements. We compare the emissions to emissions levels compatible with the climate target of keeping the global average warming below 2 degree above the pre-industrial level. Our results suggest that under some circumstances dietary shift will be required to meet a 2 degree target.
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| 3. |
- Hedenus, Fredrik, 1976, et al.
(författare)
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The importance of reduced meat and dairy consumption for meeting stringent climate change targets
- 2014
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Ingår i: Climatic Change. - : Springer Science and Business Media LLC. - 1573-1480 .- 0165-0009. ; 124:1-2, s. 79-91
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Tidskriftsartikel (refereegranskat)abstract
- For agriculture, there are three major options for mitigating greenhouse gas (GHG) emissions: 1) productivity improvements, particularly in the livestock sector; 2) dedicated technical mitigation measures; and 3) human dietary changes. The aim of the paper is to estimate long-term agricultural GHG emissions, under different mitigation scenarios, and to relate them to the emissions space compatible with the 2°C temperature target. Our estimates include emissions up to 2070 from agricultural soils, manure management, enteric fermentation and paddy rice fields, and are based on IPCC Tier 2 methodology. We find that baseline agricultural CO2-equivalent emissions (using Global Warming Potentials with a 100 year time horizon) will be approximately 13 Gton CO(2)eq/year in 2070, compared to 7.1 Gton CO(2)eq/year 2000. However, if faster growth in livestock productivity is combined with dedicated technical mitigation measures, emissions may be kept to 7.7 Gton CO(2)eq/year in 2070. If structural changes in human diets are included, emissions may be reduced further, to 3-5 Gton CO(2)eq/year in 2070. The total annual emissions for meeting the 2°C target with a chance above 50 % is in the order of 13 Gton CO(2)eq/year or less in 2070, for all sectors combined. We conclude that reduced ruminant meat and dairy consumption will be indispensable for reaching the 2°C target with a high probability, unless unprecedented advances in technology take place.
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| 4. |
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| 5. |
- Svensson, Lars, 1963-, et al.
(författare)
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From Tutor to Producer : Changes in the design space of online education
- 2010
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Ingår i: Proceedings of the 33rd IRIS Seminar. 2010.. - Rebild, Denmark.
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Konferensbidrag (refereegranskat)abstract
- In recent years online and blended learning has scaled up from being a pilot endeavour driven by pioneers, to constituting a large portion of many institutions of higher education. In the process, the conditions for the online teacher has gradually changed, and the situation of today is in many ways problematic where student interaction and dialogue has to stand back in favour of time consuming content production, material delivery, and technical problem solving. This paper draws on the experiences from a Scandinavian University to illustrate how this transition can be understood in the light of rapid technological development in combination with slow evolution of pedagogical models for online education.
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