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- Hedberg, P., et al.
(författare)
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Mitral annulus motion as a predictor of mortality in a community-based sample of 75-year-old men and women
- 2006
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Ingår i: Journal of the American Society of Echocardiography. - : Elsevier BV. - 0894-7317 .- 1097-6795. ; 19:1, s. 88-94
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Tidskriftsartikel (refereegranskat)abstract
- Mitral annulus motion (MAM) is a predictor of mortality in selected patient groups, but its prognostic value in less selected populations is not known. In a community-based random sample of 75-year-old men and women (n = 408), left ventricular function was measured as: (1) maximum amplitude of MAM; and (2) wall-motion index. During a median follow-up of 7.2 years, 83 persons died (26 from cardiac causes). Left ventricular function as measured by MAM predicted the risk of all-cause and cardiac mortality independently of other potential risk factors in this community-based sample. Regarding cardiac mortality, the predictive ability of MAM was also independent of left ventricular systolic function measured as wall-motion index. MAM may prove to be a valuable complement to other echocardiographic methods in the assessment of prognosis in less selected populations.
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| 2. |
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| 3. |
- Nilsson, G, et al.
(författare)
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White blood cell counts associate more strongly to the metabolic syndrome in 75-year-old women than in men : a population based study.
- 2007
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Ingår i: Metabolic Syndrome and Related Disorders. - : Mary Ann Liebert Inc. - 1540-4196 .- 1557-8518. ; 5:4, s. 359-364
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Tidskriftsartikel (refereegranskat)abstract
- Background: A positive relation between the metabolic syndrome (MetS) and inflammatoryactivity has been reported. The purpose of this investigation was to study the relationshipsbetween 1) white blood cell (WBC) count and MetS, 2) WBC count and the individual com-ponents of MetS and 3) WBC count and insulin sensitivity in 75-year-old women and menfrom the general population. Methods: The study included 200 women and 196 men comprising 64% of the 75-year oldpeople from the city of Västerås in Sweden. MetS was defined according to the National Cho-lesterol Education Program (NCEP). Results: WBC count (109/L; median and interquartile range) was 5.7 (4.9–6.8) for women and6.3 (5.4–7.2) for men, P Ͻ .001 for gender difference. For women with and without MetS, WBCcount was 6.3 (5.3–7.3) and 5.4(4.7–6.3), respectively. For men the corresponding figures were6.7 (5.9–7.6) and 6.1 (5.4–7.1).The difference in WBC count between individuals with and with-out MetS was significant (P Ͻ .001 for women; P ϭ .014 for men). All individual componentsof MetS (with exception of blood pressure) were more strongly associated with WBC countfor women than for men. Insulin sensitivity, measured as HOMA-IR (HOmeostasis ModelAssessment-Insulin Resistance) index, was significantly associated with WBC count in wo-men but not in men. Conclusions: In this elderly population, individuals with MetS had a higher WBC countthan those without. Women had a lower WBC count and stronger relationship between WBCcount and insulin sensitivity than did men.
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