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Sökning: WFRF:(Kenny Owen) > (2020-2024)

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  • 2021
  • swepub:Mat__t
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  • Falster, Daniel, et al. (författare)
  • AusTraits, a curated plant trait database for the Australian flora
  • 2021
  • Ingår i: Scientific Data. - : Nature Portfolio. - 2052-4463. ; 8:1
  • Tidskriftsartikel (refereegranskat)abstract
    • We introduce the AusTraits database - a compilation of values of plant traits for taxa in the Australian flora (hereafter AusTraits). AusTraits synthesises data on 448 traits across 28,640 taxa from field campaigns, published literature, taxonomic monographs, and individual taxon descriptions. Traits vary in scope from physiological measures of performance (e.g. photosynthetic gas exchange, water-use efficiency) to morphological attributes (e.g. leaf area, seed mass, plant height) which link to aspects of ecological variation. AusTraits contains curated and harmonised individual- and species-level measurements coupled to, where available, contextual information on site properties and experimental conditions. This article provides information on version 3.0.2 of AusTraits which contains data for 997,808 trait-by-taxon combinations. We envision AusTraits as an ongoing collaborative initiative for easily archiving and sharing trait data, which also provides a template for other national or regional initiatives globally to fill persistent gaps in trait knowledge.
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  • Krizsan, Sophie Julie, et al. (författare)
  • Characterization and in vitro assessment of seaweed bioactives with potential to reduce methane production
  • 2022
  • Ingår i: FRONTIERS IN ANIMAL SCIENCE. - : Frontiers Media SA. - 2673-6225. ; 3
  • Tidskriftsartikel (refereegranskat)abstract
    • This study collates compositional analysis of seaweeds data with information generated from in vitro gas production assays in the presence and absence of seaweeds. The aim was to assess and rank 27 native northern European seaweeds as potential feed ingredients for use to reduce methane emissions from ruminants. It provides information for use in future in vivo dietary trials concerning feed manipulation strategies to reduce CH4 emissions efficiently from domestic ruminants based on dietary seaweed supplementation. The seaweeds H. siliquosa and A. nodosum belonging to phylum Phaeophyta displayed the highest concentration of phlorotannins and antioxidant activity among the macroalgae giving anti-methanogenic effect in vitro, while this explanation was not valid for the observed reduction in methane when supplementing with C. filum and L. digitata in this study. D. carnosa and C. tenuicorne belonging to phylum Rhodophyta had the highest protein content among the macroalgae that reduced methane production in vitro. There were no obvious explanation from the compositional analysis conducted in this study to the reduced methane production in vitro when supplementing with U. lactuca belonging to phylum Chlorophyta. The strongest and most complete methane inhibition in vitro was observed when supplementing with Asparagopsis taxiformis that was used as a positive control in this study.
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  • Mahmood, Rashid, et al. (författare)
  • Assessment of antidiabetic potential and phytochemical profiling of Rhazya stricta root extracts
  • 2020
  • Ingår i: BMC Complementary Medicine and Therapies. - : Springer Nature. - 2662-7671. ; 20:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Diabetes mellitus is a chronic disease characterized by hyperglycemia that may occur due to genetic, environmental or lifestyle factors. Natural remedies have been used to treat diabetes since long and many antidiabetic compounds of varied efficacies have been isolated from medicinal plants. Rhazya stricta has been used for decades for the treatment of diabetes mellitus and associated ailments. Considering the folkloric use of R. stricta against diabetes, it was aimed to investigate the effectiveness of its root extracts against diabetes through in vitro assays and in vivo studies using animal model along with phytochemical profiling through GCMS. Methods: Various fractions of Rhazya stricta obtained through column chromatography were evaluated for a variety of assays including a-glucosidase, Dipeptidyl peptidase-IV (DPP-IV), beta-secretase and Glucagon-like peptide-1 (GLP-1) secretion studies. For the in vivo studies the alloxan-induced diabetic mice were treated with root extracts and blood glucose levels, HbA1C, and other biochemical markers along with the histological study of the liver were done. The phytochemical identification was performed using an Agilent 7890B GC coupled to a 7010 Triple Quadrupole (MS/MS) system. GraphPad Prism software version 5.01 was used for statistical analysis. Results: Majority of the extract fractions showed excellent results against diabetes by inhibiting enzymes DPP-IV (Up to 61%) and beta-secretase (Up to 83%) with IC50s 979 pg/ml and 169 mu g/ml respectively with increase in the GLP1 secretion. The results of in vivo studies indicated a marked reduction in blood glucose and HbA1c levels along with positive effects on other parameters like lipid profile, liver functions and renal functions of extract-treated mice as compared to control. The histological examination of the liver demonstrated hepatoprotective effects against diabetes led changes and various classes of phytochemicals were also identified through GCMS in different fractions. Conclusion: The results revealed strong antidiabetic activity of R. stricta root with the potential to protect body organs against diabetic changes. Moreover, a variety of phytochemicals has also been identified through GCMS that might be responsible for the antidiabetic potential of Rhazya stricta root.
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