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Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma

Toussaint, Laura (author)
Aarhus University Hospital,Aarhus Univ Hosp, Danish Ctr Particle Therapy, Aarhus, Denmark.
Brandal, Petter (author)
Oslo university hospital,Oslo Univ Hosp, Dept Oncol, Oslo, Norway.;Oslo Univ Hosp, Inst Canc Genet & Informat, Oslo, Norway.
Embring, Anna (author)
Karolinska University Hospital,Karolinska Univ Hosp, Dept Oncol, Stockholm, Sweden.
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Engellau, Jacob (author)
Skåne University Hospital,Skane Univ Hosp, Dept Hematol Oncol & Radiat Phys, Lund, Sweden.
Evensen, Morten Egeberg (author)
Oslo university hospital,Oslo Univ Hosp, Dept Oncol, Oslo, Norway.
Griskeviskius, Romualdas (author)
Natl Canc Inst, Dept Med Phys, Vilnius, Lithuania.
Hansen, Jolanta (author)
Aarhus University Hospital,Aarhus Univ Hosp, Dept Oncol, Aarhus, Denmark.
Hietala, Henna (author)
Oulu University Hospital,Oulu Univ Hosp, Dept Oncol & Radiotherapy, Oulu, Finland.
Wickart Johansson, Gun (author)
Karolinska University Hospital,Karolinska Univ Hosp, Dept Oncol, Stockholm, Sweden.
Jørgensen, Morten (author)
Copenhagen University Hospital,Copenhagen Univ Hosp, Dept Oncol, Rigshosp, Copenhagen, Denmark.
Kramer, Paul Heinz (author)
University Hospital Essen,Essen Univ Hosp, West German Proton Therapy Ctr Essen, Essen, Germany.
Kristensen, Ingrid (author)
Lund University,Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Strålterapi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Radiation therapy,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skane Univ Hosp, Dept Hematol Oncol & Radiat Phys, Lund, Sweden.
Lehtio, Kaisa (author)
Oulu University Hospital,Oulu Univ Hosp, Dept Oncol & Radiotherapy, Oulu, Finland.
Magelssen, Henriette (author)
Oslo university hospital,Oslo Univ Hosp, Dept Oncol, Oslo, Norway.
Maraldo, Maja Vestmø (author)
Copenhagen University Hospital,Copenhagen Univ Hosp, Dept Oncol, Rigshosp, Copenhagen, Denmark.
Marienhagen, Kirsten (author)
University Hospital of North Norway,Univ Hosp North Norway, Dept Oncol, Tromso, Norway.
Martinsson, Ulla (author)
Uppsala universitet,Experimentell och klinisk onkologi,Uppsala University Hospital
Nilsson, Kristina, 1967- (author)
Uppsala universitet,Experimentell och klinisk onkologi,Uppsala University Hospital
Peters, Sarah (author)
University Hospital Essen,Univ Hosp Essen, Dept Particle Therapy, Essen, Germany.
Plaude, Sandija (author)
University Hospital Essen,Essen Univ Hosp, West German Proton Therapy Ctr Essen, Essen, Germany.
Seiersen, Klaus (author)
Aarhus University Hospital,Aarhus Univ Hosp, Danish Ctr Particle Therapy, Aarhus, Denmark.
Sendiuliene, Daiva (author)
Natl Canc Inst, Dept External Beam Radiotherapy, Vilnius, Lithuania.
Smulders, Bob (author)
Copenhagen University Hospital,Aarhus University Hospital,Aarhus Univ Hosp, Danish Ctr Particle Therapy, Aarhus, Denmark.;Copenhagen Univ Hosp, Dept Oncol, Rigshosp, Copenhagen, Denmark.
Edvardsen, Tone (author)
University Hospital of North Norway,Univ Hosp North Norway, Dept Oncol, Tromso, Norway.
Søbstad, Johan Martin (author)
University Hospital of North Norway,Univ Hosp North Norway, Dept Oncol, Tromso, Norway.
Taheri Kadkhoda, Zarah (author)
Uppsala universitet,Medicinsk strålningsvetenskap,Uppsala University Hospital
Vaalavirta, Leila (author)
Helsinki University Central Hospital,Helsinki Univ Hosp, Dept Oncol, Helsinki, Finland.
Vestergaard, Anne (author)
Aarhus University Hospital,Aarhus Univ Hosp, Danish Ctr Particle Therapy, Aarhus, Denmark.
Timmermann, Beate (author)
University Hospital Essen,Essen Univ Hosp, West German Proton Therapy Ctr Essen, Essen, Germany.;Univ Hosp Essen, Dept Particle Therapy, Essen, Germany.;German Canc Consortium DKTK, West German Canc Ctr WTZ, Essen, Germany.
Lassen-Ramshad, Yasmin (author)
Aarhus University Hospital,Aarhus Univ Hosp, Danish Ctr Particle Therapy, Aarhus, Denmark.
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Aarhus University Hospital Aarhus Univ Hosp, Danish Ctr Particle Therapy, Aarhus, Denmark (creator_code:org_t)
 
Informa UK Limited, 2022
2022
English 4 s.
In: Acta Oncologica. - : Informa UK Limited. - 0284-186X .- 1651-226X. ; 61:2, s. 235-238
Related links:
http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
https://doi.org/10.1...
https://urn.kb.se/re...
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  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Postoperative radiotherapy for intracranial paediatric ependymoma is challenging both for target definition and treatment planning [1]. Delineation of the tumour bed is difficult, as structures in prior contact with the tumour will shift back into their original positions after surgery. In infratentorial cases, the target is adjacent to the brainstem and upper spinal cord, therefore the relatively high prescription dose and sparing of surrounding organs at risk (OARs) need to be balanced. Through the radiotherapy working-group of the Nordic Organization of Pediatric Hematology and Oncology (NOPHO) and in collaboration with the Westdeutsches Protonentherapizentrum Essen (WPE), a study was performed to quantify inter-centre variations in target delineation and treatment plans for these tumours.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

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