| 1. |
- Jena, Manoj Kumar, et al.
(författare)
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Molecular complexity of mammary glands development : a review of lactogenic differentiation in epithelial cells
- 2023
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Ingår i: Artificial Cells, Nanomedicine and Biotechnology. - 2169-1401. ; 51:1, s. 491-508
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Tidskriftsartikel (refereegranskat)abstract
- The mammary gland is a dynamic organ with various physiological processes like cellular proliferation, differentiation, and apoptosis during the pregnancy-lactation-involution cycle. It is essential to understand the molecular changes during the lactogenic differentiation of mammary epithelial cells (MECs, the milk-synthesizing cells). The MECs are organized as luminal milk-secreting cells and basal myoepithelial cells (responsible for milk ejection by contraction) that form the alveoli. The branching morphogenesis and lactogenic differentiation of the MECs prepare the gland for lactation. This process is governed by many molecular mediators including hormones, growth factors, cytokines, miRNAs, regulatory proteins, etc. Interestingly, various signalling pathways guide lactation and understanding these molecular transitions from pregnancy to lactation will help researchers design further research. Manipulation of genes responsible for milk synthesis and secretion will promote augmentation of milk yield in dairy animals. Identifying protein signatures of lactation will help develop strategies for persistent lactation and shortening the dry period in farm animals. The present review article discusses in details the physiological and molecular changes occurring during lactogenic differentiation of MECs and the associated hormones, regulatory proteins, miRNAs, and signalling pathways. An in-depth knowledge of the molecular events will aid in developing engineered cellular models for studies related to mammary gland diseases of humans and animals.
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| 2. |
- Kim, Min Seo, et al.
(författare)
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Global burden of peripheral artery disease and its risk factors, 1990-2019 : a systematic analysis for the Global Burden of Disease Study 2019
- 2023
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Ingår i: The Lancet Global Health. - : Elsevier. - 2214-109X. ; 11:10, s. E1553-E1565
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Tidskriftsartikel (refereegranskat)abstract
- Background: Peripheral artery disease is a growing public health problem. We aimed to estimate the global disease burden of peripheral artery disease, its risk factors, and temporospatial trends to inform policy and public measures.Methods: Data on peripheral artery disease were modelled using the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2019 database. Prevalence, disability-adjusted life years (DALYs), and mortality estimates of peripheral artery disease were extracted from GBD 2019. Total DALYs and age-standardised DALY rate of peripheral artery disease attributed to modifiable risk factors were also assessed.Findings: In 2019, the number of people aged 40 years and older with peripheral artery disease was 113 million (95% uncertainty interval [UI] 99 center dot 2-128 center dot 4), with a global prevalence of 1 center dot 52% (95% UI 1 center dot 33-1 center dot 72), of which 42 center dot 6% was in countries with low to middle Socio-demographic Index (SDI). The global prevalence of peripheral artery disease was higher in older people, (14 center dot 91% [12 center dot 41-17 center dot 87] in those aged 80-84 years), and was generally higher in females than in males. Globally, the total number of DALYs attributable to modifiable risk factors in 2019 accounted for 69 center dot 4% (64 center dot 2-74 center dot 3) of total peripheral artery disease DALYs. The prevalence of peripheral artery disease was highest in countries with high SDI and lowest in countries with low SDI, whereas DALY and mortality rates showed U-shaped curves, with the highest burden in the high and low SDI quintiles.Interpretation: The total number of people with peripheral artery disease has increased globally from 1990 to 2019. Despite the lower prevalence of peripheral artery disease in males and low-income countries, these groups showed similar DALY rates to females and higher-income countries, highlighting disproportionate burden in these groups. Modifiable risk factors were responsible for around 70% of the global peripheral artery disease burden. Public measures could mitigate the burden of peripheral artery disease by modifying risk factors.
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| 3. |
- Awasthi, Mukesh Kumar, et al.
(författare)
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Advanced approaches for resource recovery from wastewater and activated sludge: A review
- 2023
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Ingår i: Bioresource Technology. - 0960-8524 .- 1873-2976. ; 384
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Forskningsöversikt (refereegranskat)abstract
- Due to resource scarcity, current industrial systems are switching from waste treatment, such as wastewater treatment and biomass, to resource recovery (RR). Biofuels, manure, pesticides, organic acids, and other bioproducts with a great market value can be produced from wastewater and activated sludge (AS). This will not only help in the transition from a linear economy to a circular economy, but also contribute to sustainable development. However, the cost of recovering resources from wastewater and AS to produce value-added products is quite high as compared to conventional treatment methods. In addition, most antioxidant technologies remain at the laboratory scale that have not yet reached the level at industrial scale. In order to promote the innovation of resource recovery technology, the various methods of treating wastewater and AS to produce biofuels, nutrients and energy are reviewed, including biochemistry, thermochemistry and chemical stabilization. The limitations of wastewater and AS treatment methods are prospected from biochemical characteristics, economic and environmental factors. The biofuels derived from third generation feedstocks, such as wastewater are more sustainable. Microalgal biomass are being used to produce biodiesel, bioethanol, biohydrogen, biogas, biooils, bioplastics, biofertilizers, biochar and biopesticides. New technologies and policies can promote a circular economy based on biological materials.
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| 4. |
- Li, Yue, et al.
(författare)
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Sustainable Conversion of Biowaste to Energy to Tackle the Emerging Pollutants: A Review
- 2023
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Ingår i: Current Pollution Reports. - : Springer. - 2198-6592.
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Forskningsöversikt (refereegranskat)abstract
- Biowaste is a major source of organic material that can be converted into energy through various processes such as anaerobic digestion, composting, and pyrolysis. However, emerging pollutants, such as pharmaceuticals, pesticides, herbicides, and personal and household products, are a growing concern in wastewater treatment that can be effectively removed by biowaste-to-energy processes. While these contaminants pose significant challenges, the development and implementation of effective monitoring programs and risk assessment tools help to mitigate their impact on human health and the environment. Likewise, monitoring programs, challenges, legislations, and risk assessment tools are essential for understanding and managing the risks associated with emerging pollutants. Biowaste recycling is an important aspect of a biocircular economy perspective as it involves the conversion of organic waste into valuable resources that can be reused sustainably. The review discusses the modern approaches that offer several advantages, including reducing the waste disposal and generating renewable energy while addressing emerging wastewater treatment pollutants. To achieve the goal of a circular economy, modern biotechnological approaches including anaerobic digestion, composting, bioleaching, bioremediation, and microbial fuel cells offer a sustainable and effective way to convert waste into valuable products. These bioproducts alongside energy generation using waste-to-energy technologies can provide economic benefits through revenue generation, reduced waste disposal costs, and improved resource efficiency. To achieve a biocircular economy for biowaste valorization, several stakeholders, including waste collectors, waste management companies, policymakers, and consumers need to be involved. The sustainable conversion of biowaste to energy is an essential and instrumental technology in environmental sustainability.
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| 5. |
- Kumar R, Avinash, et al.
(författare)
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The hydraulic and thermal performances of rectangular and square microchannel with different hydraulic diameters cooled by graphene–platinum hybrid nanofluid
- 2022
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Ingår i: Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science. - : SAGE Publications. - 2041-2983 .- 0954-4062. ; 236:13, s. 7473-7483
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Tidskriftsartikel (refereegranskat)abstract
- The objective of this paper is to analyze the effect of hydraulic diameter and channel shape on the thermal and hydrodynamic characteristics of a microchannel cooled by Graphene–Platinum/water hybrid nanofluid for electronic cooling applications. The study was performed numerically using mathematical software called Maple 19.0. Microchannels having square and rectangular cross-sections, and hydraulic diameters ranging from 200 µm to 1,000 µm were taken into consideration. Thermal resistance, heat transfer coefficient, pressure drop, and friction factor were evaluated for different conditions and their corresponding graphs are presented and discussed. It was evident from the results that low thermal resistance and high heat transfer coefficient was achieved upon decreasing the hydraulic diameter, which is favorable for the cooling of electronic chips and devices. Based on the Reynolds number, the heat transfer coefficient increased by 2–4 times for both rectangular and square microchannels, on decreasing the hydraulic diameter from highest value (1,000 µm) to lowest value (200 µm). However, friction factor and pressure drop increased for channels with lower hydraulic diameters. In addition, rectangular microchannels exhibited better heat transfer performance, while square microchannels had lower friction factor and pressure drop. Rectangular microchannels presented a maximum enhancement of 30% in heat transfer coefficient and a reduction of 18% in thermal resistance, when compared to square microchannels. The results also suggested that the performance of microchannels with 500 µm hydraulic diameter is balanced, considering both heat transfer performance and pressure drop constraints.
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| 6. |
- Basu, Bikramjit, et al.
(författare)
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Friction and Wear of Ceramics : Principles and Case Studies
- 2020
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- This book covers the area of tribology broadly, providing important introductory chapters to fundamentals, processing, and applications of tribology. The book is designed primarily for easy and cohesive understanding for students and practicing scientists pursuing the area of tribology with focus on materials. This book helps students and practicing scientists alike understand that a comprehensive knowledge about the friction and wear properties of advanced materials is essential to further design and development of new materials.The description of the wear micromechanisms of various materials will provide a strong background to the readers as how to design and develop new tribological materials. This book also places importance on the development of new ceramic composites in the context of tribological applications. The various sections of the book discuss fundamentals of nature and properties of materials, friction and wear of structural ceramics, bioceramics, biocomposites, and nanoceramics, as well as lightweight composites and friction and wear of ceramics in a cryogenic environment.Some of the key features of the book include: Fundamentals section highlights the salient issues of ceramic processing and mechanical properties of important oxide and non-oxide ceramic systems; State of the art research findings on important ceramic composites are included and an understanding on the behavior of silicon carbide (SiC) based ceramic composites in dry sliding wear conditions is presented as a case study; Erosion wear behavior of ceramics, in which case studies on high temperature erosion behavior of SiC based composites and zirconium diboride (ZrB2) based composites is also covered; Wear behavior of ceramic coatings is rarely discussed in any tribology related books therefore a case study explaining the abrasion wear behavior of WC-Co coating is provided. Finally an appendix chapter is included in which a collection of several types of questions including multiple choice, short answer and long answer ae provided.
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| 7. |
- Clark, David, et al.
(författare)
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Management and outcomes following emergency surgery for traumatic brain injury – A multi-centre, international, prospective cohort study (the Global Neurotrauma Outcomes Study)
- 2020
-
Ingår i: International Journal of Surgery Protocols. - : IJS Press. - 2468-3574. ; 20, s. 1-7
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: Traumatic brain injury (TBI) accounts for a significant amount of death and disability worldwide and the majority of this burden affects individuals in low-and-middle income countries. Despite this, considerable geographical differences have been reported in the care of TBI patients. On this background, we aim to provide a comprehensive international picture of the epidemiological characteristics, management and outcomes of patients undergoing emergency surgery for traumatic brain injury (TBI) worldwide. Methods and analysis: The Global Neurotrauma Outcomes Study (GNOS) is a multi-centre, international, prospective observational cohort study. Any unit performing emergency surgery for TBI worldwide will be eligible to participate. All TBI patients who receive emergency surgery in any given consecutive 30-day period beginning between 1st of November 2018 and 31st of December 2019 in a given participating unit will be included. Data will be collected via a secure online platform in anonymised form. The primary outcome measures for the study will be 14-day mortality (or survival to hospital discharge, whichever comes first). Final day of data collection for the primary outcome measure is February 13th. Secondary outcome measures include return to theatre and surgical site infection. Ethics and dissemination: This project will not affect clinical practice and has been classified as clinical audit following research ethics review. Access to source data will be made available to collaborators through national or international anonymised datasets on request and after review of the scientific validity of the proposed analysis by the central study team.
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| 8. |
- Dixit, Rishibha, et al.
(författare)
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Effect of Various Growth Medium on the Physiology and De Novo Lipogenesis of a Freshwater Microalga Scenedesmus rotundus-MG910488 under Autotrophic Condition
- 2022
-
Ingår i: Clean Technologies. - : MDPI. - 2571-8797. ; 4:3, s. 733-751
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Tidskriftsartikel (refereegranskat)abstract
- The microalga Scenedesmus rotundus, isolated from Jabalpur, Madhya Pradesh, India was designated as Scenedesmus rotundus-MG910488 after morphological and molecular identification. In this study, the effects of various autotrophic growth media on the physiology and lipid accumulation of this microalga were investigated. The cell density, amount of photosynthetic pigments, the productivity of biomass and lipid content and the cell morphology of the microalga were shown to be significantly affected by the variation in growth media. The highest biomass of 754.56 +/- 14.80 mg L-1 with biomass productivity of 37.73 +/- 0.74 mg L(-1)day(-1) was achieved when this microalgae was cultivated in the Zarrouk's medium, whereas the highest lipid content of 33.30 +/- 1.21% was observed in the BG-11 medium. The results confirm that the BG-11 is a cost-effective and efficient growth medium for this microalga. It also shows that the ingredients of the growth medium and its concentration influence the growth and synthesis of biomolecules produced by microalga. The biodiesel produced from obtained lipids was qualitatively estimated by Gas Chromatography-Mass Spectroscopy (GC-MS), Nuclear Magnetic Resonance (H-1, C-13 NMR) and Fourier Transform-Infrared Spectroscopy (FT-IR), which indicate the presence of oleic acid methyl ester, linoleic acid methyl ester and palmitic acid methyl ester as the leading fatty acid methyl esters (FAME) in the samples, which make this strain an ideal feedstock for biodiesel production.
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| 9. |
- Ghosalya, Manoj Kumar, et al.
(författare)
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Solar light driven atomic and electronic transformations in a plasmonic Ni@NiO/NiCO3 photocatalyst revealed by ambient pressure X-ray photoelectron spectroscopy
- 2024
-
Ingår i: Catalysis Science and Technology. - 2044-4753. ; 14:11, s. 3029-3040
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Tidskriftsartikel (refereegranskat)abstract
- This work employs ambient pressure X-ray photoelectron spectroscopy (APXPS) to delve into the atomic and electronic transformations of a core-shell Ni@NiO/NiCO3 photocatalyst - a model system for visible light active plasmonic photocatalysts used in water splitting for hydrogen production. This catalyst exhibits reversible structural and electronic changes in response to water vapor and solar simulator light. In this study, APXPS spectra were obtained under a 1 millibar water vapor pressure, employing a solar simulator with an AM 1.5 filter to measure spectral data under visible light illumination. The in situ APXPS spectra indicate that the metallic Ni core absorbs the light, exciting plasmons, and creates hot electrons that are subsequently utilized through hot electron injection in the hydrogen evolution reaction (HER) by NiCO3. Additionally, the data show that NiO undergoes reversible oxidation to NiOOH in the presence of water vapor and light. The present work also investigates the contribution of carbonate and its involvement in the photocatalytic reaction mechanism, shedding light on this seldom-explored aspect of photocatalysis. The APXPS results highlight the photochemical reduction of carbonates into -COOH, contributing to the deactivation of the photocatalyst. This work demonstrates the APXPS efficacy in examining photochemical reactions, charge transfer dynamics and intermediates in potential photocatalysts under near realistic conditions.
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| 10. |
- Hedegård, Lars, 1979-, et al.
(författare)
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Eu regulations and their impact on the Indian textile & apparel industry
- 2023
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Ingår i: Textile Times. - New Delhi : Confederation of Indian Textile Industry (CITI). ; XVIII:09, s. 26-31
-
Tidskriftsartikel (populärvet., debatt m.m.)abstract
- The article describes how the European Union is committed to transforming European production and consumption and achieving a circular economy. The transformation is supported by policy work, and especially crucial for the fashion and textile industry are the European green deal, the Circular economy action plan, the EU waste policy, the strategy for sustainable and circular textiles, and the digital product passport project. The article ends with reflections on how the European transformation influences the production of fashion and textiles in India.
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| 11. |
- Islam, Jamil, et al.
(författare)
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Graphene as thinnest coating on copper electrodes in microbial methanol fuel cells
- 2023
-
Ingår i: ACS Nano. - : American Chemical Society (ACS). - 1936-0851 .- 1936-086X. ; 17:1, s. 137-145
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Tidskriftsartikel (refereegranskat)abstract
- Dehydrogenation of methanol (CH3OH) into direct current (DC) in fuel cells can be a potential energy conversion technology. However, their development is currently hampered by the high cost of electrocatalysts based on platinum and palladium, slow kinetics, the formation of carbon monoxide intermediates, and the requirement for high temperatures. Here, we report the use of graphene layers (GL) for generating DC electricity from microbially driven methanol dehydrogenation on underlying copper (Cu) surfaces. Genetically tractable Rhodobacter sphaeroides 2.4.1 (Rsp), a nonarchetypical methylotroph, was used for dehydrogenating methanol at the GL-Cu surfaces. We use electrochemical methods, microscopy, and spectroscopy methods to assess the effects of GL on methanol dehydrogenation by Rsp cells. The GL-Cu offers a 5-fold higher power density and 4-fold higher current density compared to bare Cu. The GL lowers charge transfer resistance to methanol dehydrogenation by 4 orders of magnitude by mitigating issues related to pitting corrosion of underlying Cu surfaces. The presented approach for catalyst-free methanol dehydrogenation on copper electrodes can improve the overall sustainability of fuel cell technologies.
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| 12. |
- Kabir, Zarina Nahar, et al.
(författare)
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mHealth based intervention by social care professionals to support family caregivers to persons with dementia living at home in Sweden (Caregiver Connect) : A randomized controlled trial
- 2024
-
Ingår i: BMC Geriatrics. - 1471-2318. ; 24
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The majority of persons with dementia in Sweden reside in their own homes with support from family members. Approximately, 12% of persons with dementia have immigrant background. Within the next 20 years, the number of persons with dementia who are non-ethnic Swedes is said to double. Family caregivers with immigrant backgrounds are noted to receive less support in the community than ethnic Swedes and rate their health status lower than ethnic Swedish peers. The Swedish National Board of Health and Welfare have highlighted the importance of follow-up support for family caregivers with immigrant backgrounds as there is a recognized gap in research and available information tailored to meet the needs of this group.PURPOSE OF THE STUDY: The purpose of the study is to test effectiveness of an mHealth based intervention through which community social workers can improve caregiving competence of non-European immigrant family caregivers of people with dementia living at home in Sweden. The overarching aim is to reduce caregiver burden and depressive symptoms, and improve quality of life.METHODS: A randomized controlled trial (RCT) including wait list control group will be performed consisting of an intervention group (A, n = 44) and a wait list control group (B, n = 44), totaling a sample size of 88. On completion of the 10-weeks long intervention in the intervention group, the intervention will be delivered to group B. Effect of the intervention will be analyzed between and within groups over time. The content of the educational component of the intervention is inspired by the iSupport manual developed by the World Health Organization. The contents, in the form of a booklet, aims to equip the family caregivers with structured information on understanding dementia as a condition and its management at home, including self-care guidance designed specifically for family caregivers themselves.DISCUSSION: Similar telephone-delivered intervention studies targeted for family caregivers to persons with dementia are ongoing in Malaysia and will start in India using the same booklet adapted to the local context. These studies will provide evidence on the effectiveness of using digital technologies to deliver support to those who may not be reached or adequately served by the traditional healthcare system.TRIAL REGISTRATION: ISRCTN registry, Registration number ISRCTN64235563.
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| 13. |
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| 14. |
- Krebs, Alice, et al.
(författare)
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The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods
- 2020
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Ingår i: Archives of Toxicology. - : Springer Science and Business Media LLC. - 0340-5761 .- 1432-0738. ; 94:7, s. 2435-2461
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Tidskriftsartikel (refereegranskat)abstract
- Hazard assessment, based on new approach methods (NAM), requires the use of batteries of assays, where individual tests may be contributed by different laboratories. A unified strategy for such collaborative testing is presented. It details all procedures required to allow test information to be usable for integrated hazard assessment, strategic project decisions and/or for regulatory purposes. The EU-ToxRisk project developed a strategy to provide regulatorily valid data, and exemplified this using a panel of > 20 assays (with > 50 individual endpoints), each exposed to 19 well-known test compounds (e.g. rotenone, colchicine, mercury, paracetamol, rifampicine, paraquat, taxol). Examples of strategy implementation are provided for all aspects required to ensure data validity: (i) documentation of test methods in a publicly accessible database; (ii) deposition of standard operating procedures (SOP) at the European Union DB-ALM repository; (iii) test readiness scoring accoding to defined criteria; (iv) disclosure of the pipeline for data processing; (v) link of uncertainty measures and metadata to the data; (vi) definition of test chemicals, their handling and their behavior in test media; (vii) specification of the test purpose and overall evaluation plans. Moreover, data generation was exemplified by providing results from 25 reporter assays. A complete evaluation of the entire test battery will be described elsewhere. A major learning from the retrospective analysis of this large testing project was the need for thorough definitions of the above strategy aspects, ideally in form of a study pre-registration, to allow adequate interpretation of the data and to ensure overall scientific/toxicological validity.
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| 15. |
- Pal, Rudrajeet, Full Professor, et al.
(författare)
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Circular used clothing valorization: Executive Brief
- 2023
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Rapport (populärvet., debatt m.m.)abstract
- This Executive Brief compiles the key results obtained from some ongoing research and innovation studies conducted with the scope of two ongoing projects: (i) CLOSeD (Circular clothing dichotomies in global-local supply chain dispersion) funded by Ikea Family Research Foundation; ongoing since January 2021, and (ii) Circular Logistics (Exploring the role of logistics in the circular textile ecosystem) funded by Formas (Swedish research council for sustainable development); ongoing since May 2022. [More about the 2 projects here: CLOSeD↗ Circular Logistics↗]This Executive Brief is one-of-its-kind, given that it synthesizes the results of multiple ongoing studies, and draws connection among them by presenting an overarching purpose of creating science-based logical reasoning and understanding of how circular clothing supply chains and ecosystems, and the organizations embedded within, can maximise their valorisation potential amid the changing landscape led by, for example, the European Union (EU)-wide planning and adoption of “EU Strategy for textiles”. A common thread of our argument, as put forward in this Executive Brief is while the textile circular economy is largely influenced in practice by recent technological advancements, related to circular material development, innovative products and processes, or digitalization of circular business models and operations, the motivation in driving them forward has been largely from an efficiency-gain perspective, both in terms of economics and ecology, that is address whether and how circular economy would minimise costs, enhance profitability, and render economies of scale. A novelty-centred perspective has been largely implicit in this regard; however critical to generate a top-line on how circular supply chains and ecosystems should generate sustainable value, beyond cost/profit dimensions.To address this our Executive Brief presents the 5 distinct studies’ results. Each study is enriched by empirically-driven dataset, analytical framing and scientific methodology, while at the same time are aligned by a common objective: to explore and provide explanation of the main challenges to value generation in circular clothing supply chains and ecosystems, and what concrete strategic solutions are/can be devised. Ø STUDY 1 explores the values currently uncaptured, new opportunities and strategies to capture them, from a multi-dimensional and multi-stakeholder perspective, in context to European used clothing circular supply chain from multiple countries.Ø STUDY 2 checks the triple-bottom line sustainability credential of distributed Global North-South used clothing circular supply chain, by weighing the pros and cons against each other and finally proposing what needs further attention for future valorization.Ø STUDY 3 highlights the underlying supply chain capabilities prerequisite to design textile-to-textile recycling value chain for handling post-consumer waste in Global North.Ø STUDY 4 presents the case of a multi-national Swedish fashion retailer to pen down what capabilities are essential of an ecosystem leader or captain in orchestrating circular supply chains of post-consumer used clothes.Ø STUDY 5 initiates a mapping of multi-tiered textile recycling value chain in Global South by presenting the case of Panipat in India - world’s largest mechanical recycling hub.
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| 16. |
- Paras, Manoj Kumar, et al.
(författare)
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A sustainable model based on genetic algorithm for garment redesign process
- 2023
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Ingår i: Journal of Fashion Marketing and Management. - : Emerald. - 1361-2026 .- 1758-7433. ; 27:5, s. 870-887
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Tidskriftsartikel (refereegranskat)abstract
- PurposeThis study proposes a garment modularization model based on an interactive genetic algorithm. The suggested model consists of extraction and identification of parts and the determination and implementation of connections. Rules and corresponding mathematical equations have been formulated for the part's extractions from the discarded products and connections for the redesigned products.Design/methodology/approachSustainability entices scholars and practitioners while referring to reducing waste to control environmental degradation. One of the ways to safeguard natural resources is to increase the reuse of old or discarded products. The current study focuses on the redesign process to improve the reuse of products.FindingsThe intelligent system proposed based on the modularization techniques is expected to simplify and quantify the redesign process. The model can further help in the minimization of wastage and environmental degradation.Originality/valuePresently, manual decisions are taken by the designers based on their memory, experience and intuition to extract and join the parts.
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| 17. |
- Paras, Manoj Kumar, et al.
(författare)
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A sustainable model based on genetic algorithm for garment redesign process
- 2023
-
Ingår i: Journal of Fashion Marketing and Management. - : Emerald Group Publishing Limited. - 1361-2026 .- 1758-7433. ; 27:5, s. 870-887
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Tidskriftsartikel (refereegranskat)abstract
- PurposeThis study proposes a garment modularization model based on an interactive genetic algorithm. The suggested model consists of extraction and identification of parts and the determination and implementation of connections. Rules and corresponding mathematical equations have been formulated for the part's extractions from the discarded products and connections for the redesigned products.Design/methodology/approachSustainability entices scholars and practitioners while referring to reducing waste to control environmental degradation. One of the ways to safeguard natural resources is to increase the reuse of old or discarded products. The current study focuses on the redesign process to improve the reuse of products.FindingsThe intelligent system proposed based on the modularization techniques is expected to simplify and quantify the redesign process. The model can further help in the minimization of wastage and environmental degradation.Originality/valuePresently, manual decisions are taken by the designers based on their memory, experience and intuition to extract and join the parts.
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| 18. |
- Paras, Manoj Kumar, et al.
(författare)
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An exploratory study of Swedish and Romanian organisations to investigate upcycling practice in the clothing industry
- 2023
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Ingår i: Research Journal of Textile and Apparel. - : Emerald Group Publishing Limited. - 1560-6074.
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Tidskriftsartikel (refereegranskat)abstract
- PurposeThe process of redesigning is one of the essential steps in upcycling, which comprises ideation, reconstruction and fitting. This paper aims to study the best practice of upcycling in the clothing industry. This study is an attempt to standardise upcycling/redesign process.Design/methodology/approachAn exploratory approach was adopted to perform the research. This study draws on the multiple organisations involved in the upcycling of clothes. The organisations chosen for this study are located in Sweden and Romania using the snowball technique. Semi-structured interviews, direct and participatory observation approaches were used to collect information. The collected data are systematically analysed using NVivo 10 software.FindingsThis paper provides empirical insights into the diverse practices of upcycling. Process, product and demand-based were three fundamental approaches to performing the redesigning process. The fabric quality and durability, variations in size, colour and pattern, skills and efforts required in the extraction of parts and environmental consciousness and awareness were the main factors influencing upcycling process.Research limitations/implicationsThe use of the European case may miss best practices from the other region. This study may help scholars to understand the method of upcycling. A practitioner of upcycling can use the findings to improve and standardise the existing process. This research is beneficial for society, as this leads to the reduction of textile wastage.Originality/valueThis paper conceptualises some of the best practices of clothes redesign. This provides a good insight for the organisation for the improvement in the redesign business.
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| 19. |
- Paras, Manoj Kumar, et al.
(författare)
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Reverse logistics in the sustainable fashion supply chain
- 2021. - 1
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Ingår i: Supply Chain Management and Logistics in the Global Fashion Sector. - London : Routledge. - 9781003089063 ; , s. 216-232
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Bokkapitel (refereegranskat)abstract
- Reverse logistics is a concept that maximizes utility of a product after its end-of-life or end-of use. Different disposition options such as reuse, repair, recycle, remanufacture, incineration and land-filling determine the flow of the product through reverse logistics. In reverse logistics the products flow upstream from consumers as they are returned for recycling or reuse. Multiple aspects of reverse logistics in the fashion industry are highlighted in this chapter, including criteria for effective decision-making along the different value-addition stages of collection, sorting, reprocessing and upcycling. Mostly the charity organizations carry out reverse value chain of the fashion products though new forms of collaboration are evolving to tap this potential market. The process of up-cycling is not so popular in practice even though maximum valorisation of the product can be attained through it. Availability of fashionable products at a lower cost acts as a barrier to the growth of reverse logistics in the fashion industry. Apart from emphasizing these characteristics, the chapter more specifically argues that there are six critical success factors that influence reverse logistics performance in the fashion industry. These are: (i) strategic partnership and collaboration, (ii) design for “second” life consideration, (iii) optimal recovery processes and channel structure, (iv) access to information, (v) legislative and regulatory instruments, and (vi) consumer relationship management and awareness building.
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| 20. |
- Shaw, Abinash Kumar, et al.
(författare)
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Detecting galaxies in a large H I spectral cube
- 2022
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Ingår i: Journal of astrophysics and astronomy. - : Springer Science and Business Media LLC. - 0250-6335 .- 0973-7758. ; 43:2
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Tidskriftsartikel (refereegranskat)abstract
- The upcoming square kilometer array (SKA) is expected to produce humongous amount of data for undertaking H I science. We have developed an MPI-based PYTHON pipeline to deal with the large data efficiently with the present computational resources. Our pipeline divides such large H I 21-cm spectral cubes into several small cubelets, and then processes them in parallel using publicly available H I source finder SOFIA-2. The pipeline also takes care of sources at the boundaries of the cubelets and also filters out false and redundant detections. By comapring with the true source catalog, we find that the detection efficiency depends on the SOFIA-2 parameters, such as the smoothing kernel size, linking length and threshold values. We find the optimal kernel size for all flux bins to be between 3–5 and 7–15 pixels, respectively, in the spatial and frequency directions. Comparing the recovered source parameters with the original values, we find that the output of SOFIA-2 is highly dependent on kernel sizes and a single choice of kernel is not sufficient for all types of H I galaxies. We also propose the use of alternative methods to SOFIA-2, which can be used in our pipeline to find sources more robustly.
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| 21. |
- Singh, Rajendra, et al.
(författare)
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Review, Analysis, and Implementation of Path Selection Strategies for 2D NoCs
- 2022
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Ingår i: IEEE Access. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 2169-3536. ; 10, s. 129245-129268
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Tidskriftsartikel (refereegranskat)abstract
- Recent advances in very-large-scale integration (VLSI) technologies have offered the capability of integrating thousands of processing elements onto a single silicon microchip. Multiprocessor systems-on-chips (MPSoCs) are the latest creation of this technology evolution. As an interconnection network, Network-on-Chip (NoC) has emerged as a scalable and promising solution for MPSoCs to achieve high performance. In NoCs, a routing algorithm is a critical part of a router and provides a path for a packet toward its destination. Every routing algorithm should exhibit two characteristics. First, the route selection function should provide enough degree of adaptiveness to avoid network congestion. Second, it should not offer stale information on network congestion status to the neighboring routers. Many researchers have investigated network congestion and proposed techniques to control/avoid congestion. Such congestion avoidance-based algorithms significantly improve NoC performance. However, they may result in hardware overhead for side network implementation to collect congestion status. This paper reviews various output selection strategies used by routing algorithms to route a packet on a less congested network region. It also classifies them based on techniques adopted to handle and propagate congestion information. Additionally, this article provides the implementation and analysis details of state-of-art selection methods.
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| 22. |
- Singh Tuli, Hardeep, et al.
(författare)
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Luteolin, a Potent Anticancer Compound : From Chemistry to Cellular Interactions and Synergetic Perspectives
- 2022
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Ingår i: Cancers. - : MDPI AG. - 2072-6694. ; 14:21
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Forskningsöversikt (refereegranskat)abstract
- Increasing rates of cancer incidence and the toxicity concerns of existing chemotherapeutic agents have intensified the research to explore more alternative routes to combat tumor. Luteolin, a flavone found in numerous fruits, vegetables, and herbs, has exhibited a number of biological activities, such as anticancer and anti-inflammatory. Luteolin inhibits tumor growth by targeting cellular processes such as apoptosis, cell-cycle progression, angiogenesis and migration. Mechanistically, luteolin causes cell death by downregulating Akt, PLK-1, cyclin-B1, cyclin-A, CDC-2, CDK-2, Bcl-2, and Bcl-xL, while upregulating BAX, caspase-3, and p21. It has also been reported to inhibit STAT3 signaling by the suppression of STAT3 activation and enhanced STAT3 protein degradation in various cancer cells. Therefore, extensive studies on the anticancer properties of luteolin reveal its promising role in chemoprevention. The present review describes all the possible cellular interactions of luteolin in cancer, along with its synergistic mode of action and nanodelivery insight.
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| 23. |
- Stark, Sari, et al.
(författare)
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Decreased soil microbial nitrogen under vegetation 'shrubification' in the subarctic forest–tundra ecotone : the potential role of increasing nutrient competition between plants and soil microorganisms
- 2023
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Ingår i: Ecosystems. - : Springer Nature. - 1432-9840 .- 1435-0629. ; 26:7, s. 1504-1523
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Tidskriftsartikel (refereegranskat)abstract
- The consequences of warming-induced ‘shrubification’ on Arctic soil carbon storage are receiving increased attention, as the majority of ecosystem carbon in these systems is stored in soils. Soil carbon cycles in these ecosystems are usually tightly coupled with nitrogen availability. Soil microbial responses to ‘shrubification’ may depend on the traits of the shrub species that increase in response to warming. Increase in deciduous shrubs such as Betula nana likely promotes a loss of soil carbon, whereas the opposite may be true if evergreen shrubs such as Empetrum hermaphroditum increase. We analyzed soil organic matter stocks and 13C NMR fractions, microbial CO2 respiration, biomass, extracellular enzyme activities (EEAs), and their association with shrub density in northern Sweden after 20 years of experimental warming using open top chambers (OTCs). Our study sites were located in a tundra heath that stores high soil carbon quantities and where the OTCs had increased deciduous shrubs, and in a mountain birch forest that stores lower soil carbon quantities and where the OTCs had increased evergreen shrubs. We predicted that organic matter stocks should be lower and respiration and EEAs higher inside the OTCs than untreated plots in the tundra, whereas no effect should be detected in the forest. Soil organic matter stocks and 13C NMR fractions remained unaffected at both sites. When expressed as per gram microbial biomass, respiration and EEAs for carbohydrate and chitin degradation were higher inside the OTCs, and contrasting our prediction, this effect was stronger in the forest. Unexpectedly, the OTCs also led to a substantially lower microbial biomass carbon and nitrogen irrespective of habitat. The decline in the microbial biomass counteracted increased activities resulting in no effect of the OTCs on respiration and a lower phenol oxidase activity per gram soil. Microbial biomass nitrogen correlated negatively with evergreen shrub density at both sites, indicating that ‘shrubification’ may have intensified nutrient competition between plants and soil microorganisms. Nutrient limitation could also underlie increased respiration per gram microbial biomass through limiting C assimilation into biomass. We hypothesize that increasing nutrient immobilization into long-lived evergreen shrubs could over time induce microbial nutrient limitation that contributes to a stability of accumulated soil organic matter stocks under climate warming.
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| 24. |
- Trivedi, Maitrayee, et al.
(författare)
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Study of Cucurbit[7]uril nanocoating on epitaxial graphene to design a versatile sensing platform
- 2021
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Ingår i: Applied Surface Science. - : ELSEVIER. - 0169-4332 .- 1873-5584. ; 563
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Tidskriftsartikel (refereegranskat)abstract
- Present study aimed to develop nanocoating of cucurbit[7]uril (CB[7]) on surfaces of silicon and epitaxial graphene using drop casting and spin coating techniques. Here, we report a systematic study for the influence of sonication, probe sonication, and centrifugation time on the dispersion of CB[7] in aqueous solutions for the preparation of high-quality CB[7] nanocoating. Spin speed, spin time, and spin acceleration have been optimised to attain uniform films with minimum rms. Atomic force microscopy is used to study morphology, rms, and height of CB[7] nanocoating under different parameters. The presence of CB[7] on the nanocoating and its binding nature was determined by Infrared absorption and X-ray photoelectron spectroscopy. The present method of CB[7] nanocoating preparation is easy, versatile, scalable, and does not need the addition of electrolyte additives. Prepared CB[7] films are high-quality, uniform, and could be used as a novel sensing platform to tether required functional groups.
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| 25. |
- Yadav, Vikas, et al.
(författare)
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Emerging role of microRNAs as regulators of protein kinase C substrate MARCKS and MARCKSL1 in cancer
- 2024
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Ingår i: Experimental Cell Research. - 0014-4827. ; 434:2
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Forskningsöversikt (refereegranskat)abstract
- MicroRNAs (miRNAs) have emerged as pivotal regulators of gene expression, playing essential roles in diverse cellular processes, including the development and progression of cancer. Among the numerous proteins influenced by miRNAs, the MARCKS/MARCKSL1 protein, a key regulator of cellular cytoskeletal dynamics and membrane-cytosol communication, has garnered significant attention due to its multifaceted involvement in various cancer-related processes, including cell migration, invasion, metastasis, and drug resistance. Motivated by the encouraging early clinical success of peptides targeting MARCKS in several pathological conditions, this review article delves into the intricate interplay between miRNAs and the MARCKS protein in cancer. Herein, we have highlighted the latest findings on specific miRNAs that modulate MARCKS/MARCKSL1 expression, providing a comprehensive overview of their roles in different cancer types. We have underscored the need for in-depth investigations into the therapeutic feasibility of targeting the miRNA-MARCKS axis in cancer, taking cues from the successes witnessed in related fields. Unlocking the full potential of miRNA-mediated MARCKS regulation could pave the way for innovative and effective therapeutic interventions against various cancer types.
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