| 1. |
- Gustafsson, Tomas, et al.
(författare)
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Emissions from integrated iron and steel industry i Sweden : Model for estimation and allocation of energy consump-tion and CO2 emissions for reporting to the UNFCCC
- 2011
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- SSAB’s two integrated iron and steel production plants in Luleå and Oxelösund are among the largest point sources of greenhouse gases in Sweden. Their reported emissions included in Sweden’s annual submission to the UNFCCC have been reviewed and revised in several previous studies. In a 2010 SMED pilot study it was concluded that there was a need to further review the energy allocation model for the Luleå and Oxelösund plants as well as the reported energy consumption and CO2 emissions from excess energy gases utilized outside the SSAB premises for power and heat production. In the light of the pilot study, this study aimed at de-veloping a robust and sustainable model for present reported time-series for future estimations.In cooperation with SSAB representatives, information on annual material input, calorific values and energy flows were assessed and used as basis for estimation of total energy consumption and model for energy allocation. In addition, energy statistics from Statistics Sweden and EU ETS data were evaluated. The results show that the present estimations of energy consumption in the IPCC energy sector based on data from the plant-specific annual environmental reports and energy statistics from Statistics Sweden are sufficient also for future reporting to the UNFCCC. Furthermore, this report includes recommendations on revisions and future reporting of CO2 emissions from combustion of SSAB excess energy gases (reported in CRF 1A1a) as well as of energy allocated to non-energy use of fuels in industrial processes (CRF 2C1) and feedstocks (CRF 1Ad).
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| 2. |
- Halldén, Christer, et al.
(författare)
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Origin of Swedish hemophilia B mutations
- 2013
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Ingår i: Journal of Thrombosis and Haemostasis. - : Elsevier BV. - 1538-7933 .- 1538-7836. ; 11:11, s. 2001-2008
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Tidskriftsartikel (refereegranskat)abstract
- Background More than 1100 mutations that cause hemophilia B (HB) have been identified. At the same time, specific F9 mutations are present at high frequencies in certain populations, which raise questions about the origin of HB mutations. ObjectivesTo describe the mutation spectrum of all HB families in Sweden and investigate if mutations appearing in several families are due to independent recurrent mutations (RMs) or to a common mutation event (i.e. are identical by descent (IBD)). Patients/MethodsThe registered Swedish HB population consists of patients from 86 families. Mutations were identified by resequencing and identical haplotypes were defined using 74 markers and a control population of 285 individuals. The ages of IBD mutations were estimated using ESTIAGE. ResultsOut of 77 presumably unrelated patients with substitution mutations, 47 patients (61%) had mutations in common with other patients. Haplotyping of the 47 patients showed that 24 patients had IBD mutations (51%) with estimated ages of between two and 23 generations. A majority of these patients had mild disease. Eight of the 15 mutations observed in more than one family were C>T transitions in CpG sites and all eight were RMs. ConclusionsThe association of IBD mutations with a mild phenotype is similar to what has been previously observed in hemophilia A. Noteworthy features of the mutations that are common to more than one family are the equal proportions of patients with RM and IBD mutations and the correlation between the occurrence of RMs and C>T transitions at CpG sites.
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| 3. |
- Ljung, R., et al.
(författare)
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Hemophilia B families with the same mutation are often related : a survey of the Swedish population
- 2012
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Ingår i: Haemophilia (ISSN 1351-8216) 2012: 18 (supplement 3), p. 109. ; , s. 109-109
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Aim: To study if families with hemophilia B in Sweden carrying the same mutation are identical by descent (IBD) or the result of independent mutations (RM).Study group: A total of 77 presumed unrelated and unselected Swedish families with hemophilia B comprising all clinical severities (total and large deletions not included). Control group of 256 healthy individuals.Methods: Haplotyping was performed using 90 SNP markers (11 within the F9 gene) and 1 microsatellite marker. The frequencies of shared haplotypes were determined in the control group, and the ages of the shared haplotypes will be determined using the program ESTIAGE.Results: Analysis of the mutations gave the following results: 5 small deletions (<10bp), 2 small insertions (<10bp), 3 splice site mutations, 14 nonsense mutations, and 53 missense mutations. A total of 30 mutations (39%) occurred in a single individual only, whereas the remaining 47 mutations occurred in 2 or more individuals; 7 mutations occurred in 2 individuals, 4 mutations occurred in 3 individuals, 2 mutations occurred in 4 individuals, 1 mutation occurred in 6 individuals, and 1 mutation occurred in 7 individuals each, i.e., 47 mutations out of 77 (61%) were either IBD or recurrent mutation. Haplotyping and comparisons with the control group classified 21/47 mutations as IBD and 25/47 as RM. The phenotypes of the 21 IBD individuals were mild (17), moderate 2), and severe (1); those of the 25 RM individuals were mild (7), moderate (7), and severe (12). Age estimation of the mutations is ongoing.Conclusion: Many families with hemophilia B, in particular those with milder forms, carrying the same mutation are IBD, i.e., revision of ‘‘hot-spots’’ for mutation is needed.
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| 4. |
- Ljung, R., et al.
(författare)
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Hemophilia B families with the same mutation are often related : a survey of the Swedish population
- 2012
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Ingår i: Haemophilia. - : Wiley. - 1351-8216.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Aim: To study if families with hemophilia B in Sweden carrying the same mutation are identical by descent (IBD) or the result of independent mutations (RM). Study group: A total of 77 presumed unrelated and unselected Swedish families with hemophilia B comprising all clinical severities (total and large deletions not included). Control group of 256 healthy individuals. Methods: Haplotyping was performed using 90 SNP markers (11 within the F9 gene) and 1 microsatellite marker. The frequencies of shared haplotypes were determined in the control group, and the ages of the shared haplotypes will be determined using the program ESTIAGE. Results: Analysis of the mutations gave the following results: 5 small deletions (<10bp), 2 small insertions (<10bp), 3 splice site mutations, 14 nonsense mutations, and 53 missense mutations. A total of 30 mutations (39%) occurred in a single individual only, whereas the remaining 47 mutations occurred in 2 or more individuals; 7 mutations occurred in 2 individuals, 4 mutationsoccurred in 3 individuals, 2 mutations occurred in 4 individuals, 1 mutation occurred in 6 individuals, and 1 mutation occurred in 7 individuals each, i.e., 47 mutations out of 77 (61%) were either IBD or recurrent mutation. Haplotyping and comparisons with the control group classified 21/47 mutations as IBD and 25/47 as RM. The phenotypes of the 21 IBD individuals were mild (17), moderate 2), and severe (1); those of the 25 RM individuals were mild (7), moderate (7), and severe (12). Age estimation of the mutations is ongoing. Conclusion: Many families with hemophilia B, in particular those with milder forms, carrying the same mutation are IBD, i.e., revision of ‘‘hot-spots’’ for mutation is needed.
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| 5. |
- Viberg, Andreas, et al.
(författare)
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Archaeological prospection of a high altitude Neolithic site in the Arctic mountain tundra region of northern Sweden
- 2013
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Ingår i: Journal of Archaeological Science. - : Elsevier BV. - 0305-4403 .- 1095-9238. ; 40:6, s. 2579-2588
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Tidskriftsartikel (refereegranskat)abstract
- During the summer of 2008 archaeological excavations and geophysical prospection surveys were carried out in the mountain tundra region of north-eastern Sweden. The investigations focused on locating settlement remains connected with a Middle Neolithic tool production site discovered by archaeologists in 2001. Magnetic susceptibility surveys using the MS2D system by Bartington Instruments and an EM38 by Geonics measuring the Inphase component of the electromagnetic field were used for the prospection of measurable traces of anthropogenic activity and structures such as hearths and middens within the estimated settlement area. Soil samples for phosphate analysis were also collected and analysed using a field analysis method developed by Merck. The magnetic susceptibility measurements successfully located a waste heap containing fire-cracked stones and refuse from a seasonal settlement. The results of the survey were confirmed by subsequent archaeological excavations, which also revealed a piece of resin with the imprint of a human tooth. One additional piece of resin dated the site to 3340-3100 BC. The soil phosphate analysis showed slightly increased values over the central part of the site and over the heap of fire-cracked stones. Comparison between the MS2D and EM38 measurements revealed a weak impact of the bedrock on the results, indicating a potential for the applicability of magnetic surveys to this specific type of environment. Future geophysical archaeological prospection in the Swedish mountain tundra region could benefit from a combined approach using high-resolution magnetometry and magnetic susceptibility measurements.
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