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Patch Testing With ...
Patch Testing With Nickel Sulfate 5.0% Traces Significantly More Contact Allergy Than 2.5% : A Prospective Study Within the International Contact Dermatitis Research Group
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- Svedman, Cecilia (author)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Ale, Iris (author)
- University of the Republic
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- Goh, Chee Leok (author)
- National Skin Centre
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- Goncalo, Margarida (author)
- University Hospital of Coimbra
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- Lee, Jun Young (author)
- Catholic University of Korea
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- Ljubojevic Hadžavdić, Suzana (author)
- University of Zagreb,University Hospital Centre Zagreb
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- Matsunaga, Kayoko (author)
- Fujita Health University
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- Bach, Rasmus Overgaard (author)
- Odense University Hospital
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- Pratt, Melanie (author)
- The Ottawa Hospital,University of Ottawa
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- Puangpet, Pailin (author)
- Institute of Dermatology Thailand
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- Sasseville, Denis (author)
- McGill University Health Centre, Montreal General Hospital
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- Andersen, Klaus E. (author)
- Odense University Hospital
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- Dahlin, Jakob (author)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Suzuki, Kayoko (author)
- Fujita Health University
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- Yagami, Akiko (author)
- Fujita Health University
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- Bruze, Magnus (author)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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(creator_code:org_t)
- 2022
- 2022
- English 4 s.
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In: Dermatitis. - 1710-3568. ; 33:6, s. 417-420
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
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- Background Nickel allergy is the most common contact allergy, and a nickel salt is, therefore, included in most baseline patch test series. In the baseline series of the International Contact Dermatitis Research Group and the American Contact Dermatitis Society, nickel sulfate hexahydrate (NSH) in petrolatum at 2.5% is included, whereas NSH at 5.0% is included in many other baseline series, such as the European and Swedish ones. Objective The aim of the study is to investigate whether NSH at 5.0% detects significantly more contact allergy than NSH 2.5% when both preparations are tested simultaneously in consecutive dermatitis patients. Patients and Methods Two thousand two hundred eighty-seven consecutive dermatitis patients were patch tested simultaneously with NSH in petrolatum at 2.5% and 5.0%. The allergy rates were compared for all clinics individually and combined using McNemar test, 2-sided. Results Contact allergy to NSH 5.0% and 2.5% was found in 20.3% and 16.8%, respectively (P < 0.0001). In 6 of 11 clinics, significantly more patients tested positive to the higher NSH concentration. For the 2 clinics in North America combined, significantly more patients tested positive to NSH 5.0%. Conclusions The NSH preparation in the International Contact Dermatitis Research Group baseline patch test series should be considered to be changed from NSH 2.5% (1 mg NSH/cm2) to 5.0% (2 mg NSH/cm2).
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
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Dermatitis
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- By the author/editor
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Svedman, Cecilia
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Ale, Iris
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Goh, Chee Leok
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Goncalo, Margari ...
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Lee, Jun Young
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Ljubojevic Hadža ...
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Matsunaga, Kayok ...
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Bach, Rasmus Ove ...
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Pratt, Melanie
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Puangpet, Pailin
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Sasseville, Deni ...
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Andersen, Klaus ...
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Dahlin, Jakob
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Suzuki, Kayoko
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Yagami, Akiko
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Bruze, Magnus
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Dermatology and ...
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Dermatitis
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Lund University