| 1. |
- Hillier, Ladeana W, et al.
(författare)
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Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution
- 2004
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Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 432:7018, s. 695-716
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Tidskriftsartikel (refereegranskat)abstract
- We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the chicken is a modern descendant of the dinosaurs and the first non-mammalian amniote to have its genome sequenced, the draft sequence of its genome--composed of approximately one billion base pairs of sequence and an estimated 20,000-23,000 genes--provides a new perspective on vertebrate genome evolution, while also improving the annotation of mammalian genomes. For example, the evolutionary distance between chicken and human provides high specificity in detecting functional elements, both non-coding and coding. Notably, many conserved non-coding sequences are far from genes and cannot be assigned to defined functional classes. In coding regions the evolutionary dynamics of protein domains and orthologous groups illustrate processes that distinguish the lineages leading to birds and mammals. The distinctive properties of avian microchromosomes, together with the inferred patterns of conserved synteny, provide additional insights into vertebrate chromosome architecture.
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| 2. |
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| 3. |
- Schlegel, C, et al.
(författare)
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K-isomers in very neutron-rich nuclei around mass 180
- 2000
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Ingår i: Physica Scripta. Topical Issues. - 0281-1847. ; T88, s. 72-76
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Tidskriftsartikel (refereegranskat)abstract
- gamma-spectroscopy methods have been used to search for microsecond isomers among the fragmentation products of a 1 GeV/nucleon Pb-208 beam. In particular the population of the known K-pi = 35/2(-) isomer in W-179 has been investigated and several new isomeric decays have been found for neutron rich nuclei in the A approximate to 180-200 mass region. The ground state band of the neutron rich N = 116 system of W-190 has been identified for the first time and we discuss its structure in comparison to neighboring systems.
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| 4. |
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| 5. |
- Armstrong, Lucas C., et al.
(författare)
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Thrombospondin 2 Inhibits Microvascular Endothelial Cell Proliferation by a Caspase-independent Mechanism
- 2002
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Ingår i: Molecular Biology of the Cell. - : American Society for Cell Biology. - 1059-1524 .- 1939-4586. ; 13:6, s. 1893-1905
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Tidskriftsartikel (refereegranskat)abstract
- The matricellular protein thrombospondin 2 (TSP2) regulates a variety of cell–matrix interactions. A prominent feature of TSP2-null mice is increased microvascular density, particularly in connective tissues synthesized after injury. We investigated the cellular basis for the regulation of angiogenesis by TSP2 in cultures of murine and human fibroblasts and endothelial cells. Fibroblasts isolated from murine and human dermis synthesize TSP2 mRNA and secrete significant amounts of immunoreactive TSP2, whereas endothelial cells from mouse lung and human dermis did not synthesize TSP2 mRNA or protein. Recombinant mouse TSP2 inhibited growth of human microvascular endothelial cells (HMVECs) mediated by basic fibroblast growth factor, insulin-like growth factor-1, epidermal growth factor, and vascular endothelial growth factor (VEGF). HMVECs exposed to TSP2 in the presence of these growth factors had a decreased proportion of cells in S and G2/M phases. HMVECs cultured with a combination of basic fibroblast growth factor, insulin-like growth factor-1, and epidermal growth factor displayed an increased proportion of nonviable cells in the presence of TSP2, but the addition of VEGF blocked this TSP2-mediated impairment of cell viability. TSP2-mediated inhibition of DNA synthesis by HMVECs in the presence of VEGF was not affected by the broad-spectrum caspase inhibitor zVAD-fmk. Similar findings were obtained with TSP1. Taken together, these observations indicate that either TSP2 or TSP1 can inhibit HMVEC proliferation by inhibition of cell cycle progression and induction of cell death, but the mechanisms responsible for TSP2-mediated inhibition of cell cycle progression are independent from those leading to cell death.
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| 6. |
- Mineva, Milena, et al.
(författare)
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A New us Isomer in 136Sb Produced in the Projectile Fission of 238U
- 2001
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Ingår i: European Physical Journal A. Hadrons and Nuclei. - 1434-6001. ; 11, s. 9-13
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Tidskriftsartikel (refereegranskat)abstract
- The neutron-rich isotope Sb-136 has been produced following the relativistic projectile fission of U-238 in an experiment performed at the Fragment Separator at GSI, Darmstadt. Delayed gamma -ray spectroscopy of the fission products has been performed after isotope separation. A new isomeric state in Sb-136 has been populated, and its lifetime measured as T-1/2 = 565(50) ns. Realistic and empirical shell-model calculations have been performed and are compared to the experimental observables.
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| 7. |
- Platter, Lucas, 1976, et al.
(författare)
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Quasiparticle properties in effective field theory
- 2003
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Ingår i: Nuclear Physics A. - 0375-9474. ; 714:1-2, s. 250-264
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Tidskriftsartikel (refereegranskat)abstract
- The quasiparticle concept is an important tool for the description of many-body systems. We study the quasiparticle properties for dilute Fermi systems with short-ranged, repulsive interactions using effective field theory. We calculate the proper self-energy contributions at order (k(F)/Lambda)(3), where A is the short-distance scale that sets the size of the effective range parameters and k(F) the Fermi momentum. The quasiparticle energy, width, and effective mass to O((k(F)/Lambda)(3)) are derived from the calculated self-energy. (C) 2002 Elsevier Science B.V. All rights reserved.
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| 8. |
- Platter, Lucas, 1976, et al.
(författare)
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Universal properties of the Four-Boson system in two dimensions
- 2004
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Ingår i: Few-Body Systems. - 1432-5411 .- 0177-7963. ; 35:3-4, s. 169-174
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Tidskriftsartikel (refereegranskat)abstract
- We consider the nonrelativistic four-boson system in two dimensions interacting via a short-range attractive potential. For a weakly attractive potential with one shallow two-body bound state with binding energy B-2, the binding energies B-N of shallow N-body bound states are universal and thus do not depend on the details of the interaction potential. We compute the four-body binding energies in an effective quantum mechanics approach. There are exactly two bound states: the ground state with B-4((0)) = 197.33(1)B-2 and one excited state with B-4((1)) = 25.5 (1)B-2. We compare our results to recent predictions for N-body bound states with large N much greater than 1.
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