| 1. |
- Kapferer-Seebacher, Ines, et al.
(författare)
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Periodontal Ehlers-Danlos Syndrome Is Caused by Mutations in C1R and C1S, which Encode Subcomponents C1r and C1s of Complement
- 2016
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Ingår i: American Journal of Human Genetics. - : Cell Press. - 0002-9297 .- 1537-6605. ; 99:5, s. 1005-1014
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Tidskriftsartikel (refereegranskat)abstract
- Periodontal Ehlers-Danlos syndrome (pEDS) is an autosomal-dominant disorder characterized by early-onset periodontitis leading to premature loss of teeth, joint hypermobility, and mild skin findings. A locus was mapped to an approximately 5.8 Mb region at 12p13.1 but no candidate gene was identified. In an international consortium we recruited 19 independent families comprising 107 individuals with pEDS to identify the locus, characterize the clinical details in those with defined genetic causes, and try to understand the physiological basis of the condition. In 17 of these families, we identified heterozygous missense or in-frame insertion/deletion mutations in C1R (15 families) or C1S (2 families), contiguous genes in the mapped locus that encode subunits C1r and C1s of the first component of the classical complement pathway. These two proteins form a heterotetramer that then combines with six C1q subunits. Pathogenic variants involve the subunit interfaces or inter-domain hinges of C1r and C1s and are associated with intracellular retention and mild endoplasmic reticulum enlargement. Clinical features of affected individuals in these families include rapidly progressing periodontitis with onset in the teens or childhood, a previously unrecognized lack of attached gingiva, pretibial hyperpigmentation, skin and vascular fragility, easy bruising, and variable musculoskeletal symptoms. Our findings open a connection between the inflammatory classical complement pathway and connective tissue homeostasis.
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| 2. |
- Malmquist, Anna, et al.
(författare)
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Hbtq+ och psykologi i en historisk tillbakablick
- 2017
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Ingår i: HBTQ+ : Psykologiska perspektiv och bemötande - Psykologiska perspektiv och bemötande. - 9789127147430 ; , s. 13-34
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Bokkapitel (refereegranskat)abstract
- De individer, identiteter, uttryck och samlevnadsformer som idag kan sammanfogas under akronymen hbtq+ har genom historien betraktas på många olika vis. Psykologin har varit central för hur hbtq+ har förståtts, definierats och behandlats. I detta kapitel betraktas hbtq+historien därför med psykologiska glasögon.
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| 3. |
- Semb, Gunvor, et al.
(författare)
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A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.
- 2017
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Ingår i: Journal of Plastic Surgery and Hand Surgery. - : Taylor & Francis. - 2000-656X .- 2000-6764. ; 51:1, s. 2-13
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND AND AIMS: Longstanding uncertainty surrounds the selection of surgical protocols for the closure of unilateral cleft lip and palate, and randomised trials have only rarely been performed. This paper is an introduction to three randomised trials of primary surgery for children born with complete unilateral cleft lip and palate (UCLP). It presents the protocol developed for the trials in CONSORT format, and describes the management structure that was developed to achieve the long-term engagement and commitment required to complete the project.METHOD: Ten established national or regional cleft centres participated. Lip and soft palate closure at 3-4 months, and hard palate closure at 12 months served as a common method in each trial. Trial 1 compared this with hard palate closure at 36 months. Trial 2 compared it with lip closure at 3-4 months and hard and soft palate closure at 12 months. Trial 3 compared it with lip and hard palate closure at 3-4 months and soft palate closure at 12 months. The primary outcomes were speech and dentofacial development, with a series of perioperative and longer-term secondary outcomes.RESULTS: Recruitment of 448 infants took place over a 9-year period, with 99.8% subsequent retention at 5 years.CONCLUSION: The series of reports that follow this introductory paper include comparisons at age 5 of surgical outcomes, speech outcomes, measures of dentofacial development and appearance, and parental satisfaction. The outcomes recorded and the numbers analysed for each outcome and time point are described in the series.TRIAL REGISTRATION: ISRCTN29932826.
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| 4. |
- Uhlén, Mathias, et al.
(författare)
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The human secretome
- 2019
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Ingår i: Science Signaling. - : American Association for the Advancement of Science (AAAS). - 1945-0877 .- 1937-9145. ; 12:609
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Tidskriftsartikel (refereegranskat)abstract
- The proteins secreted by human cells (collectively referred to as the secretome) are important not only for the basic understanding of human biology but also for the identification of potential targets for future diagnostics and therapies. Here, we present a comprehensive analysis of proteins predicted to be secreted in human cells, which provides information about their final localization in the human body, including the proteins actively secreted to peripheral blood. The analysis suggests that a large number of the proteins of the secretome are not secreted out of the cell, but instead are retained intracellularly, whereas another large group of proteins were identified that are predicted to be retained locally at the tissue of expression and not secreted into the blood. Proteins detected in the human blood by mass spectrometry-based proteomics and antibody-based immuno-assays are also presented with estimates of their concentrations in the blood. The results are presented in an updated version 19 of the Human Protein Atlas in which each gene encoding a secretome protein is annotated to provide an open-access knowledge resource of the human secretome, including body-wide expression data, spatial localization data down to the single-cell and subcellular levels, and data about the presence of proteins that are detectable in the blood.
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| 5. |
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| 6. |
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| 7. |
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| 8. |
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| 9. |
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| 10. |
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| 11. |
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| 12. |
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| 13. |
- Bexelius, Maria, et al.
(författare)
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27 forskare : Så kan EU:s murar rivas
- 2015
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Ingår i: Dagens samhälle. - : Sveriges kommuner och landsting. - 1652-6511. ; :20150923
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 14. |
- Eriksson, Kaja, et al.
(författare)
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Periodontal Health and Oral Microbiota in Patients with Rheumatoid Arthritis
- 2019
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Ingår i: Journal of Clinical Medicine. - : MDPI AG. - 2077-0383. ; 8:5
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Tidskriftsartikel (refereegranskat)abstract
- This study aimed to investigate the periodontal health of patients with established rheumatoid arthritis (RA) in relation to oral microbiota, systemic and oral inflammatory mediators, and RA disease activity. Forty patients underwent full-mouth dental/periodontal and rheumatological examination, including collection of blood, saliva, gingival crevicular fluid (GCF) and subgingival plaque. Composition of plaque and saliva microbiota were analysed using 16S rRNA sequencing and levels of inflammatory mediators by multiplex-immunoassay. The majority of the patients (75%) had moderate or severe periodontitis and the rest had no/mild periodontitis. Anti-citrullinated protein antibody (ACPA) positivity was significantly more frequent in the moderate/severe periodontitis (86%) compared to the no/mild group (50%). No significance between groups was observed for RA disease duration or activity, or type of medication. Levels of sCD30/TNFRSF8, IFN-2, IL-19, IL-26, MMP-1, gp130/sIL-6R ss, and sTNF-R1 were significantly higher in serum or GCF, and April/TNFSF13 was significantly higher in serum and saliva samples in moderate/severe periodontitis. The microbial composition in plaque also differed significantly between the two groups. In conclusion, the majority of RA patients had moderate/severe periodontitis and that this severe form of the disease was significantly associated with ACPA positivity, an altered subgingival microbial profile, and increased levels of systemic and oral inflammatory mediators.
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| 15. |
- Kvarnung, Malin, et al.
(författare)
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Ataxia in Patients With Bi-Allelic NFASC Mutations and Absence of Full-Length NF186
- 2019
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Ingår i: Frontiers in Genetics. - : Frontiers Media SA. - 1664-8021. ; 10
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Tidskriftsartikel (refereegranskat)abstract
- The etiology of hereditary ataxia syndromes is heterogeneous, and the mechanisms underlying these disorders are often unknown. Here, we utilized exome sequencing in two siblings with progressive ataxia and muscular weakness and identified a novel homozygous splice mutation (c.3020-1G > A) in neurofascin (NFASC). In RNA extracted from fibroblasts, we showed that the mutation resulted in inframe skipping of exon 26, with a deprived expression of the full-length transcript that corresponds to NFASC isoform NF186. To further investigate the disease mechanisms, we reprogrammed fibroblasts from one affected sibling to induced pluripotent stem cells, directed them to neuroepithelial stem cells and finally differentiated to neurons. In early neurogenesis, differentiating cells with selective depletion of the NF186 isoform showed significantly reduced neurite outgrowth as well as fewer emerging neurites. Furthermore, whole-cell patch-clamp recordings of patient-derived neuronal cells revealed a lower threshold for openings, indicating altered Na+ channel kinetics, suggesting a lower threshold for openings as compared to neuronal cells without the NFASC mutation. Taken together, our results suggest that loss of the full-length NFASC isoform NF186 causes perturbed neurogenesis and impaired neuronal biophysical properties resulting in a novel early-onset autosomal recessive ataxia syndrome.
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| 16. |
- Thul, Peter J., et al.
(författare)
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A subcellular map of the human proteome
- 2017
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Ingår i: Science. - : American Association for the Advancement of Science. - 0036-8075 .- 1095-9203. ; 356:6340
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Tidskriftsartikel (refereegranskat)abstract
- Resolving the spatial distribution of the human proteome at a subcellular level can greatly increase our understanding of human biology and disease. Here we present a comprehensive image-based map of subcellular protein distribution, the Cell Atlas, built by integrating transcriptomics and antibody-based immunofluorescence microscopy with validation by mass spectrometry. Mapping the in situ localization of 12,003 human proteins at a single-cell level to 30 subcellular structures enabled the definition of the proteomes of 13 major organelles. Exploration of the proteomes revealed single-cell variations in abundance or spatial distribution and localization of about half of the proteins to multiple compartments. This subcellular map can be used to refine existing protein-protein interaction networks and provides an important resource to deconvolute the highly complex architecture of the human cell.
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| 17. |
- Vadeby, Anna, 1969-, et al.
(författare)
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Säker framkomlighet : sammanfattande slutrapport 2015
- 2016
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Föreliggande rapport redovisar övergripande resultat av fyra olika åtgärder som implementerats inomTrafikverkets projekt ”Säker framkomlighet” vilket haft som syfte att förbättra framkomlighet ochtrafiksäkerhet på främst befintliga tvåfältsvägar med hastighetsgräns 90 km/tim. Åtgärderna somstuderats är: frästa mitträfflor på 2-fältsvägar, vägrensräffling på motorväg, smala mötesfria vägar(”gles 2+1-väg med räcke”) och riktningsseparerade vägar (2+1 med målad/räfflad mitt).Resultaten visar att för samtliga åtgärder har trafiksäkerhetseffekterna varit positiva med minskningarav de dödade och svårt skadade trafikanterna. Vad gäller spårdjupstillväxt visar resultaten att mitträfflinginte har en kanaliserande effekt på trafiken och därmed påverkas inte heller spårbildningen.För mötesfria vägar är den årliga spårdjupsutvecklingen cirka 25 procent högre för mötesfri väg än förmotsvarande vanlig väg för årsdygnstrafik (ÅDT) > 8 000 fordon/dygn. För lägre ÅDT är skillnaden 10–15 procent.För riktningsseparerade vägar visar resultaten endast på högre spårdjupstillväxt för ÅDT över 8 000fordon/dygn. En studie om effekter och konsekvenser av olika räffeltyper avseende buller visar att detinte finns kända argument för att inte använda sinusräffla, men ytterligare studier kring effekten förförare av tunga fordon rekommenderas. Studien avseende framkomlighetseffekter visar att andelentung trafik är en viktig faktor att beakta i utformningen av mötesfria vägar.
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| 18. |
- Aad, G., et al.
(författare)
-
- 2015
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Ingår i: Physical Review C (Nuclear Physics). - 0556-2813 .- 1089-490X. ; 92:3
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Tidskriftsartikel (refereegranskat)
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| 19. |
- Aad, G., et al.
(författare)
-
- 2015
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Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; :8
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Tidskriftsartikel (refereegranskat)
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| 20. |
- Aad, G., et al.
(författare)
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- 2015
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Tidskriftsartikel (refereegranskat)
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| 21. |
- Abbasian, Saeid, 1961-, et al.
(författare)
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How the Iranian Fire Festival in Stockholm is perceived by the visitors?
- 2019
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Ingår i: 28th Nordic Symposium on Tourism and Hospitality Research 23rd to 25th October 2019. - Roskilde, Denmark : Roskilde University. ; , s. 45-
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Konferensbidrag (refereegranskat)abstract
- Every year, a Tuesday in the middle of March and after 5:00 pm the Iranian Fire Festival (Eldfesten in Swedish, Chaharshanbe Suri in Persian) is celebrated outdoors in the center of Stockholm and ends before 10:00 pm. This event has its roots in ancient Persia, but now it is celebrated by several nations in the Middle East, Caucasus, and Central Asia. The Stockholm festival is arranged and financed by The Swedish National Theatre and several times earlier it has been opened by Swedish ministers. The event visitors are mostly of Middle Eastern background coming from Stockholm area. Since 2016 it can also be watched live through Swedish and foreign TV stations and through Social media. During the earlier years the event was held in Kungsträdgården (The Royal Garden) but this year it was arranged in the amusement park of Skansen. Ethnic cultural events in major urban areas create good images for cities and countries but also for immigrants and their neighborhoods in the city of issue (McClinchey, 2008; Loukaitou-Sideris and Soureli, 2012), and a sense of belonging among immigrants (Chacko, 2013). Many stakeholders are involved in such events (Getz et al 2007; Getz And Andersson, 2010) but perhaps the most important stakeholder is the visitors of the event. Therefore, it is of high relevance to study the visitors’ visit motivations, their perceived experience in terms of satisfaction level and their level of loyalty i.e. if they intend to visit the event next year (Savinovic et al, 2012). The aim of this research is to get insights on the visitors of the Fire Festival, their motives behind participation and how they perceive their participation afterwards. The main methods chosen in this research is participant observation and 257 completed surveys online until April 11th, 2019. Preliminary results The respondents are 63% men and 37% women, and they are mostly older than 40 (44% are older than 50). More than half of them have been living in Sweden less than 21 years of which 17% less than 5 years. 83% of the respondents call themselves Swedish-Iranians. More than 80% of the respondents have academic education (of which 7% with PhD education) and most of them are employed either by public or private sector. A considerable number of them are also either self- employed, students or retirees. They have come from different districts of Greater Stockholm while a minor part has come from municipalities outside the county. A pre-dominant majority of them have come there with friends and family members, and most of them have been participating in the festival for third times or more. Also, more than half of them have visited the Skansen park three or more times earlier. The main reasons why they celebrate the festival is to keep the old tradition and culture alive. The celebration creates feelings like happiness, pride, community, belonging, nostalgia, childhood, the Spring. Concerning the question what the place or arena means to you they either like Skansen or prefer other places in Greater Stockholm or do not care about the place but the festival and other issues such as security and safety. To the question “what do you think about celebrating the festival at Skansen” they give positive answers and to the question “are your expectations on the festival fulfilled” the majority are totally or partly agreed. They also believe that this event must be celebrated every year and give many improvement suggestions and additional critical comments such as more food trucks, better and cheaper food, more professional artists and happy songs and music.
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| 22. |
- Abelsson, Anna, et al.
(författare)
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Cardiopulmonary resuscitation quality during CPR practice versus during a simulated life-saving event
- 2018
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Ingår i: International Journal of Occupational Safety and Ergonomics. - : Taylor & Francis. - 1080-3548 .- 2376-9130. ; 24:4, s. 652-655
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Tidskriftsartikel (refereegranskat)abstract
- Introduction. As a part of the emergency medical services, the Swedish fire brigade can increase the survival rate in out-of-hospital cardiac arrests.Aim. To compare the quality of cardiopulmonary resuscitation (CPR) performed by firefighters at a routine CPR practice versus when involved in a simulated life-saving event.Methods. In this study, 80 firefighters divided into two groups performed CPR according to guidelines: one group indoors during a routine training session; the other group outdoors during a smoke diving exercise wearing personal protective clothing and self-contained breathing apparatus. Descriptive and inferential statistics were used to analyze the data.Results. The results showed a tendency for the outdoor group to perform CPR with better ventilation and compression quality, as compared to the indoor group. The ventilation of the manikin was not hampered by the firefighters wearing personal protective clothes and self-contained breathing apparatus, as the Swedish firefighters remove their facial mask and ventilate the patient with their mouth using a pocket mask.Conclusions. Overall, the results in both groups showed a high quality of CPR which can be related to the fire brigade training and education traditions. CPR training is regularly performed, which in turn helps to maintain CPR skills.
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| 23. |
- Abelsson, Anna, et al.
(författare)
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CPR performed in battlefield emergency care
- 2019
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Ingår i: Australasian Journal of Paramedicine. - : The Official Journal of Paramedics Australasia. - 2202-7270. ; 16, s. 1-9
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Tidskriftsartikel (refereegranskat)abstract
- IntroductionDuring military missions medical care is provided to military personnel as well as civilians. Although cardiopulmonary resuscitation (CPR) may not be a common task in a military field hospital, all personnel need to be trained to deal with cardiac arrest.MethodsThis study was a comparative simulation study. Participants (n=36) from the Swedish armed forces performed CPR for 2 minutes at one of three different locations: at ground level, a military bed, or a transportable military stretcher. Compression depth and rate after 2 minutes of CPR and at the time of the participants’ own request to be relieved were measured. Descriptive and inferential analysis was conducted.ResultsThere is a direct correlation between compression depth and working level, concluding that the higher working level, the lower the compression depth. There is in total an overall low percentage of participants within limits for correctly conducted CPR regarding both compression depth and rate. Time to fatigue is related to working level, where increased level results in early fatigue.ConclusionThe quality of CPR is affected by the level at which it is performed. The quality of CPR was satisfactory when working at ground level, but suboptimal when working at hospital bed level or military stretcher level. When working at raised levels, participants appeared to misjudge their own compression depth and rate. This may indicate that changes are needed when CPR is practised in the military hospital setting. Future studies regarding the use footstools are required due to the height of military beds and transportable stretchers.
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| 24. |
- Abelsson, Anna, 1971-, et al.
(författare)
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CPR performed in the military environment
- 2016
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Ingår i: Society in Europe for Simulation Applied to Medicine Lisbon 16/6 2016.. - Lisabon.
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Konferensbidrag (refereegranskat)
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| 25. |
- Abelsson, Anna, et al.
(författare)
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Military medical personnel's perceptions of treating battle injuries
- 2019
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Ingår i: Journal of military and veterans health. - : Australasian Military Medicine Association. - 1835-1271 .- 1839-2733. ; 27:2, s. 10-17
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To evaluate military personnel’s self-rated perceptions of their knowledge, experience and training after high-fidelity battle injury simulation.Design: 26 military medical personnel participated in this quantitative study. Data was collected using a questionnaire after a six-day exercise where participants self-rated 10 statements regarding having sufficient medical, practical and ethical knowledge, experience and training. Descriptive and inferential analyses were conducted to obtain the results.Results: Nurses rated themselves statistically significantly higher than medics in having sufficient medical knowledge and experience, practical knowledge, experience and training, as well as ethical knowledge and experience. The nurses also rated themselves statistically significantly higher than physicians in having practical knowledge, experience and training. Physicians’ self-rated perception was low regarding sufficient knowledge, experience and training in practical skills. Physicians, nurses and medics all reported low ratings for sufficient training in ethical issues.Discussion: Military medical personnel are required to have the knowledge and skills to work autonomously in challenging and threatening environments. For personnel that seldom see battlefield-like injuries, a clinical placement in a country with a high frequency of battlefield-like injuries would be advisable. A comparison between subjective and objective assessments may identify deficiencies in competence, which can negatively impact quality of care.
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| 26. |
- Abelsson, Anna, et al.
(författare)
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Prehospital CPR training performed with visual feedback
- 2018
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Ingår i: Disaster and Emergency Medicine Journal. - : Via Medica. - 2451-4691. ; 3:2, s. 41-45
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: Swedish firefighters are a part of the emergency medical services. Therefore, they perform prehospital cardiopulmonary resuscitation (CPR) on a regular basis. Training becomes crucial for maintaining the CPR skills and increasing the patients’ chances of survival. Training with visual feedback is for Swedish firefighters a new way of training CPR. The aim of this study was to evaluate firefighters’ perception of a CPR manikin with visual feedback.METHOD: This study had a qualitative approach. Data were collected by interviews with 16 firefighters after performing CPR on a manikin with visual feedback. The data were analyzed with a manifest content analysis.RESULTS: Visual feedback makes it easy to identify and maintain correct compression rate. There is a need for identifying too deep compressions. Uncertainty regarding the closeness to the stomach arises when using the whole hand during compressions instead of just the wrist. To accomplish an open airway requires a bit of adjustment of the manikins’ head.DISCUSSION: To train and learn CPR is feasible with visual feedback. The firefighters can maintaing a correct compression rate and correct compression depth during the sessions. Ventilating a patient with bag-valvemask or pocket mask may require training with visual feedback to guarantee the firefighters being able to secure an open airway of the patient. All these skills are essential and improve the chance of survival for the patients.
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| 27. |
- Abelsson, Anna, et al.
(författare)
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Simulation as a means to develop firefighters as emergency care professionals
- 2019
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Ingår i: International Journal of Occupational Safety and Ergonomics. - : Taylor & Francis. - 1080-3548 .- 2376-9130. ; 25:4, s. 650-657
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: The aim of this study was to evaluate the simulated emergency care performed by firefighters and their perception of simulation as an educational method.METHODS: This study had a mixed method with both a quantitative and a qualitative approach. Data were collected by simulation assessment, a questionnaire, and written comments. Descriptive analysis was conducted on the quantitative data whereas a qualitative content analysis was conducted on the qualitative data. Finally, a contingent analysis was used where a synthesis configured both the quantitative and the qualitative results into a narrative result.RESULTS: The cognitive workload that firefighters face during simulated emergency care is crucial for learning. In this study, the severity and complexity of the scenarios provided were higher than expected by the firefighters. Clearly stated conditions for the simulation and constructive feedback were considered positive for learning. Patient actors induced realism in the scenario, increasing the experience of stress, in comparison to a manikin.CONCLUSION: To simulate in a realistic on-scene environment increases firefighters' cognitive ability to critically analyze problems and manage emergency care. Simulation of emergency care developed the firefighters as professionals.
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| 28. |
- Abelsson, Anna, et al.
(författare)
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Trauma Simulation in Prehospital Emergency Care.
- 2018
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Ingår i: Journal of trauma nursing : the official journal of the Society of Trauma Nurses. - : Lippincott Williams & Wilkins. - 1078-7496 .- 1932-3883. ; 25:3, s. 201-204
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Tidskriftsartikel (refereegranskat)abstract
- Well-educated ambulance staff is a prerequisite for high-quality prehospital trauma care. The aim of this study was to examine how nurses in the ambulance service experienced participation in trauma simulation. Sixty-one nurses, working in an emergency ambulance service, performed simulated trauma care on four different occasions and afterward rated three statements on a 5-point Likert scale. A descriptive and inferential analysis was conducted. There are statistically significant increases between the pre- and posttests regarding all three statements: "I think simulation of severe trauma with manikins is realistic" (0.23 or 6% increase), "Simulation is a suitable method for learning severe trauma care" (1.3 or 38% increase), and "I am comfortable in the situation learning severe trauma care through simulation" (0.74 or 19% increase). With the experience of realism in simulation, participants become more motivated to learn and prepare for future events. If the participants instead feel uncomfortable during simulation training, they focus on their own feelings instead of learning. In a realistic simulated environment, participants are prepared to understand and manage the emergency care situation in clinical work. Participants learn during simulation when they are outside their comfort zone but without being uncomfortable or experiencing anxiety.
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| 29. |
- Abrahamsson, Annelie, et al.
(författare)
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Dense breast tissue in postmenopausal women is associated with a pro-inflammatory microenvironment in vivo
- 2016
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Ingår i: Oncoimmunology. - : TAYLOR & FRANCIS INC. - 2162-4011 .- 2162-402X. ; 5:10
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Tidskriftsartikel (refereegranskat)abstract
- Inflammation is one of the hallmarks of carcinogenesis. High mammographic density has been associated with increased risk of breast cancer but the mechanisms behind are poorly understood. We evaluated whether breasts with different mammographic densities exhibited differences in the inflammatory microenvironment.Postmenopausal women attending the mammography-screening program were assessed having extreme dense, n = 20, or entirely fatty breasts (nondense), n = 19, on their regular mammograms. Thereafter, the women were invited for magnetic resonance imaging (MRI), microdialysis for the collection of extracellular molecules in situ and a core tissue biopsy for research purposes. On the MRI, lean tissue fraction (LTF) was calculated for a continuous measurement of breast density. LTF confirmed the selection from the mammograms and gave a continuous measurement of breast density. Microdialysis revealed significantly increased extracellular in vivo levels of IL-6, IL-8, vascular endothelial growth factor, and CCL5 in dense breast tissue as compared with nondense breasts. Moreover, the ratio IL-1Ra/IL-1 was decreased in dense breasts. No differences were found in levels of IL-1, IL-1Ra, CCL2, leptin, adiponectin, or leptin:adiponectin ratio between the two breast tissue types. Significant positive correlations between LTF and the pro-inflammatory cytokines as well as between the cytokines were detected. Stainings of the core biopsies exhibited increased levels of immune cells in dense breast tissue.Our data show that dense breast tissue in postmenopausal women is associated with a pro-inflammatory microenvironment and, if confirmed in a larger cohort, suggests novel targets for prevention therapies for women with dense breast tissue.
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| 30. |
- Abulaiti, Yiming, et al.
(författare)
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A measurement of material in the ATLAS tracker using secondary hadronic interactions in 7 TeV p p collisions
- 2016
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Ingår i: Journal of Instrumentation. - : IOP PUBLISHING LTD. - 1748-0221. ; 11
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Tidskriftsartikel (refereegranskat)abstract
- Knowledge of the material in the ATLAS inner tracking detector is crucial in under-standing the reconstruction of charged-particle tracks, the performance of algorithms that identify jets containing b-hadrons and is also essential to reduce background in searches for exotic particles that can decay within the inner detector volume. Interactions of primary hadrons produced in pp collisions with the material in the inner detector are used to map the location and amount of this material. The hadronic interactions of primary particles may result in secondary vertices, which in this analysis are reconstructed by an inclusive vertex-finding algorithm. Data were collected using minimum-bias triggers by the ATLAS detector operating at the LHC during 2010 at centre-of-mass energy root s = 7 TeV, and correspond to an integrated luminosity of 19 nb(-1). Kinematic properties of these secondary vertices are used to study the validity of the modelling of hadronic interactions in simulation. Secondary-vertex yields are compared between data and simulation over a volume of about 0.7m(3) around the interaction point, and agreement is found within overall uncertainties.
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| 31. |
- Abulaiti, Yiming, et al.
(författare)
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A measurement of the calorimeter response to single hadrons and determination of the jet energy scale uncertainty using LHC Run-1 pp-collision data with the ATLAS detector
- 2017
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Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 77:1
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Tidskriftsartikel (refereegranskat)abstract
- A measurement of the calorimeter response to isolated charged hadrons in the ATLAS detector at the LHC is presented. This measurement is performed with 3.2 nb(-1) of proton-proton collision data at root s = 7 TeV from 2010 and 0.1 nb(-1) of data at root s = 8 TeV from 2012. A number of aspects of the calorimeter response to isolated hadrons are explored. After accounting for energy deposited by neutral particles, there is a 5% discrepancy in the modelling, using various sets of GEANT4 hadronic physics models, of the calorimeter response to isolated charged hadrons in the central calorimeter region. The description of the response to anti-protons at low momenta is found to be improved with respect to previous analyses. The electromagnetic and hadronic calorimeters are also examined separately, and the detector simulation is found to describe the response in the hadronic calorimeter well. The jet energy scale uncertainty and correlations in scale between jets of different momenta and pseudorapidity are derived based on these studies. The uncertainty is 2-5% for jets with transverse momenta above 2 TeV, where this method provides the jet energy scale uncertainty for ATLAS.
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| 32. |
- Abulaiti, Yiming, et al.
(författare)
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A new method to distinguish hadronically decaying boosted Z bosons from W bosons using the ATLAS detector
- 2016
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Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 76:5
-
Tidskriftsartikel (refereegranskat)abstract
- The distribution of particles inside hadronic jets produced in the decay of boosted W and Z bosons can be used to discriminate such jets from the continuum background. Given that a jet has been identified as likely resulting from the hadronic decay of a boosted W or Z boson, this paper presents a technique for further differentiating Z bosons from W bosons. The variables used are jet mass, jet charge, and a b-tagging discriminant. A likelihood tagger is constructed from these variables and tested in the simulation of W' -> WZ for bosons in the transverse momentum range 200 GeV < p(T) < 400 GeV in root s = 8 TeV pp collisions with the ATLAS detector at the LHC. For Z-boson tagging efficiencies of epsilon(Z) = 90, 50, and 10 %, one can achieve W+-boson tagging rejection factors (1/epsilon(W+)) of 1.7, 8.3 and 1000, respectively. It is not possible to measure these efficiencies in the data due to the lack of a pure sample of high p(T), hadronically decaying Z bosons. However, the modelling of the tagger inputs for boosted W bosons is studied in data using a t (t) over bar -enriched sample of events in 20.3 fb(-1) of data at root s = 8 TeV. The inputs are well modelled within uncertainties, which builds confidence in the expected tagger performance.
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| 33. |
- Abulaiti, Yiming, et al.
(författare)
-
A search for pair-produced resonances in four-jet final states at root s=13 TeV with the ATLAS detector
- 2018
-
Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 78:3
-
Tidskriftsartikel (refereegranskat)abstract
- A search for massive coloured resonances which are pair-produced and decay into two jets is presented. The analysis uses 36.7 fb(-1) of root s = 13 TeV pp collision data recorded by the ATLAS experiment at the LHC in 2015 and 2016. No significant deviation from the background prediction is observed. Results are interpreted in a SUSY simplified model where the lightest supersymmetric particle is the top squark, (t) over tilde, which decays promptly into two quarks through R-parity-violating couplings. Top squarks with masses in the range 100 GeV < m((T) over tilde) < 410 GeV are excluded at 95% confidence level. If the decay is into a b-quark and a light quark, a dedicated selection requiring two b-tags is used to exclude masses in the ranges 100 GeV < m((t) over tilde) < 470 GeV and 480 GeV < m(<(t)over tilde>) < 610 GeV. Additional limits are set on the pair-production of massive colour-octet resonances.
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| 34. |
- Abulaiti, Yiming, et al.
(författare)
-
A search for prompt lepton-jets in pp collisions at root s=8 TeV with the ATLAS detector
- 2016
-
Ingår i: Journal of High Energy Physics (JHEP). - : Springer. - 1126-6708 .- 1029-8479. ; :2
-
Tidskriftsartikel (refereegranskat)abstract
- A search is presented for a new, light boson with a mass of about 1 GeV and decaying promptly to jets of collimated electrons and/or muons (lepton-jets). The analysis is performed with 20.3 fb(-1) of data collected by the ATLAS detector at the Large Hadron Collider in proton-proton collisions at a centre-of-mass energy of 8 TeV. Events are required to contain at least two lepton-jets. This study finds no statistically significant deviation from predictions of the Standard Model and places 95% confidence-level upper limits on the contribution of new phenomena beyond the SM, incuding SUSY-portal and Higgs-portal models, on the number of events with lepton-jets.
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| 35. |
- Abulaiti, Yiming, et al.
(författare)
-
A search for top squarks with R-parity-violating decays to all-hadronic final states with the ATLAS detector in root s=8 TeV proton-proton collisions
- 2016
-
Ingår i: Journal of High Energy Physics (JHEP). - 1126-6708 .- 1029-8479. ; :6
-
Tidskriftsartikel (refereegranskat)abstract
- A search for the pair production of top squarks, each with R-parity-violating decays into two Standard Model quarks, is performed using 17.4 fb(-1) of root s = 8 TeV proton-proton collision data recorded by the ATLAS experiment at the LITC. Each top squark is assumed to decay to a b- and an 8-quark, leading to four quarks in the final state. Background discrimination is achieved with the use of b-tagging and selections on the mass and substructure of large-radius jets, providing sensitivity to top squark masses as low as 100 GeV. No evidence of an excess beyond the Standard Model background prediction is observed and top squalls decaying to bs are excluded for top squark masses in the range 100 <= m((t) over tilde) <= 315 GeV at 95% confidence level.
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| 36. |
- Abulaiti, Yiming, et al.
(författare)
-
Analysis of events with b-jets and a pair of leptons of the same charge in pp collisions at root s=8 TeV with the ATLAS detector
- 2015
-
Ingår i: Journal of High Energy Physics (JHEP). - : Springer. - 1126-6708 .- 1029-8479. ; :10
-
Tidskriftsartikel (refereegranskat)abstract
- An analysis is presented of events containing jets including at least one b-tagged jet, sizeable missing transverse momentum, and at least two leptons including a pair of the same electric charge, with the scalar sum of the jet and lepton transverse momenta being large. A data sample with an integrated luminosity of 20.3 fb(-1) of pp collisions at root s = 8 TeV recorded by the ATLAS detector at the Large Hadron Collider is used. Standard Model processes rarely produce these final states, but there are several models of physics beyond the Standard Model that predict an enhanced rate of production of such events; the ones considered here are production of vector-like quarks, enhanced fourtop-quark production, pair production of chiral b '-quarks, and production of two positively charged top quarks. Eleven signal regions are defined; subsets of these regions are combined when searching for each class of models. In the three signal regions primarily sensitive to positively charged top quark pair production, the data yield is consistent with the background expectation. There are more data events than expected from background in the set of eight signal regions defined for searching for vector-like quarks and chiral b ' quarks, but the significance of the discrepancy is less than two standard deviations. The discrepancy reaches 2.5 standard deviations in the set of five signal regions defined for searching for four-top-quark production. The results are used to set 95% CL limits on various models.
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| 37. |
- Abulaiti, Yiming, et al.
(författare)
-
Analysis of the Wtb vertex from the measurement of triple-differential angular decay rates of single top quarks produced in the t-channel at root s=8 TeV with the ATLAS detector
- 2017
-
Ingår i: Journal of High Energy Physics (JHEP). - : Springer Berlin/Heidelberg. - 1126-6708 .- 1029-8479. ; :12
-
Tidskriftsartikel (refereegranskat)abstract
- The electroweak production and subsequent decay of single top quarks in the t-channel is determined by the properties of the Wtb vertex, which can be described by the complex parameters of an effective Lagrangian. An analysis of a triple-differential decay rate in t-channel production is used to simultaneously determine five generalised helicity fractions and phases, as well as the polarisation of the produced top quark. The complex parameters are then constrained. This analysis is based on 20.2 fb(-1) of proton-proton collision data at a centre-of-mass energy of 8 TeV collected with the ATLAS detector at the LHC. The fraction of decays containing transversely polarised W bosons is measured to be f(1) = 0.30 +/- 0.05. The phase between amplitudes for transversely and longitudinally polarised W bosons recoiling against left-handed b-quarks is measured to be delta = 0.002 pi(+0.016 pi)(+0.017 pi), giving no indication of CP violation. The fractions of longitudinal or transverse W bosons accompanied by right-handed b-quarks are also constrained. Based on these measurements, limits are placed at 95% CL on the ratio of the complex coupling parameters Re [g(R)/V-L is an element of [-0.12, 0.17] and Im [g(R)/V-L is an element of [-0.07, 0.06]. Constraints are also placed on the ratios vertical bar V-R/V-L vertical bar and vertical bar g(L)/V-L vertical bar. In addition, the polarisation of single top quarks in the t-channel is constrained to be P > 0.72 (95% CL). None of the above measurements make assumptions about the value of any of the other parameters or couplings and all of them are in agreement with the Standard Model.
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| 38. |
- Abulaiti, Yiming, et al.
(författare)
-
Angular analysis of B-d(0) -> K* mu(+)mu(-) decays in pp collisions at root s=8 TeV with the ATLAS detector
- 2018
-
Ingår i: Journal of High Energy Physics (JHEP). - : SPRINGER. - 1126-6708 .- 1029-8479. ; :10
-
Tidskriftsartikel (refereegranskat)abstract
- An angular analysis of the decay B-d(0) -> K*mu(+)mu(-) is presented, based on proton-proton collision data recorded by the ATLAS experiment at the LHC. The study is using 20.3 fb(-1) of integrated luminosity collected during 2012 at centre-of-mass energy of root s = 8TeV. Measurements of the K* longitudinal polarisation fraction and a set of angular parameters obtained for this decay are presented. The results are compatible with the Standard Model predictions.
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| 39. |
- Abulaiti, Yiming, et al.
(författare)
-
Charged-particle distributions at low transverse momentum in root s=13 TeV pp interactions measured with the ATLAS detector at the LHC
- 2016
-
Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 76:9
-
Tidskriftsartikel (refereegranskat)abstract
- Measurements of distributions of charged particles produced in proton-proton collisions with a centre-of-mass energy of 13 TeV are presented. The data were recorded by the ATLAS detector at the LHC and correspond to an integrated luminosity of 151 mu b(-1). The particles are required to have a transverse momentum greater than 100 MeV and an absolute pseudorapidity less than 2.5. The charged-particle multiplicity, its dependence on transverse momentum and pseudorapidity and the dependence of the mean transverse momentum on multiplicity are measured in events containing at least two charged particles satisfying the above kinematic criteria. The results are corrected for detector effects and compared to the predictions from several Monte Carlo event generators.
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| 40. |
- Abulaiti, Yiming, et al.
(författare)
-
Charged-particle distributions in pp interactions at root s=8TeV measured with the ATLAS detector
- 2016
-
Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 76:7
-
Tidskriftsartikel (refereegranskat)abstract
- This paper presents measurements of distributions of charged particles which are produced in proton-proton collisions at a centre-of-mass energy of root s = 8TeV and recorded by the ATLAS detector at the LHC. A special dataset recorded in 2012 with a small number of interactions per beam crossing (below 0.004) and corresponding to an integrated luminosity of 160 mu b(-1) was used. A minimumbias trigger was utilised to select a data sample of more than 9 million collision events. The multiplicity, pseudorapidity, and transverse momentum distributions of charged particles are shown in different regions of kinematics and charged-particle multiplicity, including measurements of final states at high multiplicity. The results are corrected for detector effects and are compared to the predictions of various Monte Carlo event generator models which simulate the full hadronic final state.
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| 41. |
- Abulaiti, Yiming, et al.
(författare)
-
Charged-particle distributions in root s=13 TeV pp interactions measured with the ATLAS detector at the LHC
- 2016
-
Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 758, s. 67-88
-
Tidskriftsartikel (refereegranskat)abstract
- Charged-particle distributions are measured in proton-proton collisions at a centre-of-mass energy of 13 TeV, using a data sample of nearly 9 million events, corresponding to an integrated luminosity of 170 mu b(-1), recorded by the ATLAS detector during a special Large Hadron Collider fill. The charged-particle multiplicity, its dependence on transverse momentum and pseudorapidity and the dependence of the mean transverse momentum on the charged-particle multiplicity are presented. The measurements are performed with charged particles with transverse momentum greater than 500 MeV and absolute pseudorapidity less than 2.5, in events with at least one charged particle satisfying these kinematic requirements. Additional measurements in a reduced phase space with absolute pseudorapidity less than 0.8 are also presented, in order to compare with other experiments. The results are corrected for detector effects, presented as particle-level distributions and are compared to the predictions of various Monte Carlo event generators.
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| 42. |
- Abulaiti, Yiming, et al.
(författare)
-
Combination of searches for WW, WZ, and ZZ resonances in pp collisions at root s=8 TeV with the ATLAS detector
- 2016
-
Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 755, s. 285-305
-
Tidskriftsartikel (refereegranskat)abstract
- The ATLAS experiment at the CERN Large Hadron Collider has performed searches for new, heavy bosons decaying to WW, WZ and ZZ final states in multiple decay channels using 20.3 fb(-1) of pp collision data at root s = 8 TeV. In the current study, the results of these searches are combined to provide a more stringent test of models predicting heavy resonances with couplings to vector bosons. Direct searches for a charged diboson resonance decaying to WZ in the l nu l'l' (l = mu, e), llq (q) over bar, l nu q (q) over bar and fully hadronic final states are combined and upper limits on the rate of production times branching ratio to the WZ bosons are compared with predictions of an extended gauge model with a heavy W' boson. In addition, direct searches for a neutral diboson resonance decaying to WW and ZZ in the llq (q) over bar, l nu q (q) over bar, and fully hadronic final states are combined and upper limits on the rate of production times branching ratio to the WW and ZZ bosons are compared with predictions for a heavy, spin-2 graviton in an extended Randall-Sundrum model where the Standard Model fields are allowed to propagate in the bulk of the extra dimension.
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| 43. |
- Abulaiti, Yiming, et al.
(författare)
-
Constraints on non-Standard Model Higgs boson interactions in an effective Lagrangian using differential cross sections measured in the H ->gamma gamma decay channel at root s=8 TeV with the ATLAS detector
- 2016
-
Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 753, s. 69-85
-
Tidskriftsartikel (refereegranskat)abstract
- The strength and tensor structure of the Higgs boson's interactions are investigated using an effective Lagrangian, which introduces additional CP-even and CP-odd interactions that lead to changes in the kinematic properties of the Higgs boson and associated jet spectra with respect to the Standard Model. The parameters of the effective Lagrangian are probed using a fit to five differential cross sections previously measured by the ATLAS experiment in the H ->gamma gamma decay channel with an integrated luminosity of 20.3fb(-1) at root s= 8TeV. Inorder to perform a simultaneous fit to the five distributions, the statistical correlations between them are determined by re-analysing the H ->gamma gamma candidate events in the proton-proton collision data. No significant deviations from the Standard Model predictions are observed and limits on the effective Lagrangian parameters are derived. The statistical correlations are made publicly available to allow for future analysis of theories with non-Standard Model interactions.
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| 44. |
- Abulaiti, Yiming, et al.
(författare)
-
Dark matter interpretations of ATLAS searches for the electroweak production of supersymmetric particles in root s=8 TeV proton-proton collisions
- 2016
-
Ingår i: Journal of High Energy Physics (JHEP). - : Springer. - 1126-6708 .- 1029-8479. ; :9
-
Tidskriftsartikel (refereegranskat)abstract
- A selection of searches by the ATLAS experiment at the LHC for the electroweak production of SUSY particles are used to study their impact on the constraints on dark matter candidates. The searches use 20 fb(-1) of proton-proton collision data at root s = 8 TeV. A likelihood-driven scan of a five-dimensional effective model focusing on the gaugino-higgsino and Higgs sector of the phenomenological minimal supersymmetric Standard Model is performed. This scan uses data from direct dark matter detection experiments, the relic dark matter density and precision flavour physics results. Further constraints from the ATLAS Higgs mass measurement and SUSY searches at LEP are also applied. A subset of models selected from this scan are used to assess the impact of the selected ATLAS searches in this five-dimensional parameter space. These ATLAS searches substantially impact those models for which the mass m((chi) over tilde (0)(1)) of the lightest neutralino is less than 65 GeV, excluding 86% of such models. The searches have limited impact on models with larger m((chi) over tilde (0)(1)) due to either heavy electroweakinos or compressed mass spectra where the mass splittings between the produced particles and the lightest supersymmetric particle is small.
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| 45. |
- Abulaiti, Yiming, et al.
(författare)
-
Determination of spin and parity of the Higgs boson in the WW* -> ev mu v decay channel with the ATLAS detector
- 2015
-
Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 75:5
-
Tidskriftsartikel (refereegranskat)abstract
- Studies of the spin and parity quantum numbers of the Higgs boson in the WW* -> ev mu v final state are presented, based on proton-proton collision data collected by the ATLAS detector at the Large Hadron Collider, corresponding to an integrated luminosity of 20.3 fb(-1) at a centre-of-mass energy of root s = 8 TeV. The Standard Model spin-parity J(CP) = 0(++) hypothesis is compared with alternative hypotheses for both spin andCP. The case where the observed resonance is a mixture of the Standard-Model-like Higgs boson and CP-even (J(CP) = 0(++)) or CP-odd (J(CP) = 0(+-)) Higgs boson in scenarios beyond the Standard Model is also studied. The data are found to be consistent with the Standard Model prediction and limits are placed on alternative spin and CP hypotheses, including CP mixing in different scenarios.
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| 46. |
- Abulaiti, Yiming, et al.
(författare)
-
Determination of the strong coupling constant alpha(s) from transverse energy-energy correlations in multijet events at root s=8 TeV using the ATLAS detector
- 2017
-
Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 77:12
-
Tidskriftsartikel (refereegranskat)abstract
- Measurements of transverse energy-energy correlations and their associated asymmetries in multi-jet events using the ATLAS detector at the LHC are presented. The data used correspond to vs = 8 TeV proton-proton collisions with an integrated luminosity of 20.2 fb(-1). The results are presented in bins of the scalar sum of the transverse momenta of the two leading jets, unfolded to the particle level and compared to the predictions from Monte Carlo simulations. A comparison with next-to-leading-order perturbative QCD is also performed, showing excellent agreement within the uncertainties. From this comparison, the value of the strong coupling constant is extracted for different energy regimes, thus testing the running of alpha(s)(mu) predicted in QCD up to scales over 1 TeV. A global fit to the transverse energy-energy correlation distributions yields alpha(s)(m(Z)) = 0.1162 +/- 0.0011 (exp.)(-0.0070)(+0.0084) (theo.), while a global fit to the asymmetry distributions yields a value of alpha(s)(m(Z)) = 0.1196 +/- 0.0013 (exp.)(-0.0045)(+0.0075) (theo.).
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| 47. |
- Abulaiti, Yiming, et al.
(författare)
-
Dijet production in root s=7 TeV pp collisions with large rapidity gaps at the ATLAS experiment
- 2016
-
Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 754, s. 214-234
-
Tidskriftsartikel (refereegranskat)abstract
- A 6.8 nb(-1) sample of pp collision data collected under low-luminosity conditions at root s = 7 TeV by the ATLAS detector at the Large Hadron Collider is used to study diffractive dijet production. Events containing at least two jets with p(T) > 20 GeV are selected and analysed in terms of variables which discriminate between diffractive and non-diffractive processes. Cross sections are measured differentially in Delta eta(F), the size of the observable forward region of pseudorapidity which is devoid of hadronic activity, and in an estimator, (xi) over tilde, of the fractional momentum loss of the proton assuming single diffractive dissociation (pp -> pX). Model comparisons indicate a dominant non-diffractive contribution up to moderately large Delta eta(F) and small (xi) over tilde, with a diffractive contribution which is significant at the highest Delta eta(F) and the lowest (xi) over tilde. The rapidity-gap survival probability is estimated from comparisons of the data in this latter region with predictions based on diffractive parton distribution functions.
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| 48. |
- Abulaiti, Yiming, et al.
(författare)
-
Electron efficiency measurements with the ATLAS detector using 2012 LHC proton-proton collision data
- 2017
-
Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 77:3
-
Tidskriftsartikel (refereegranskat)abstract
- This paper describes the algorithms for the reconstruction and identification of electrons in the central region of the ATLAS detector at the Large Hadron Collider (LHC). These algorithms were used for all ATLAS results with electrons in the final state that are based on the 2012 pp collision data produced by the LHC at root s = 8 TeV. The efficiency of these algorithms, together with the charge misidentification rate, is measured in data and evaluated in simulated samples using electrons from Z -> ee, Z -> ee gamma and J/Psi -> ee decays. For these efficiency measurements, the full recorded data set, corresponding to an integrated luminosity of 20.3 fb(-1), is used. Based on a new reconstruction algorithm used in 2012, the electron reconstruction efficiency is 97% for electrons with E-T = 15 GeV and 99% at E-T = 50 GeV. Combining this with the efficiency of additional selection criteria to reject electrons from background processes or misidentified hadrons, the efficiency to reconstruct and identify electrons at the ATLAS experiment varies from 65 to 95%, depending on the transverse momentum of the electron and background rejection.
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| 49. |
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| 50. |
- Abulaiti, Yiming, et al.
(författare)
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Evidence for light-by-light scattering in heavy-ion collisions with the ATLAS detector at the LHC
- 2017
-
Ingår i: Nature Physics. - : Nature Publishing Group. - 1745-2473 .- 1745-2481. ; 13:9, s. 852-858
-
Tidskriftsartikel (refereegranskat)abstract
- Light-by-light scattering (gamma gamma -> gamma gamma) is a quantum-mechanical process that is forbidden in the classical theory of electrodynamics. This reaction is accessible at the Large Hadron Collider thanks to the large electromagnetic field strengths generated by ultra-relativistic colliding lead ions. Using 480 mu b(-1) of lead-lead collision data recorded at a centre-of-mass energy per nucleon pair of 5.02 TeV by the ATLAS detector, here we report evidence for light-by-light scattering. A total of 13 candidate events were observed with an expected background of 2.6 +/- 0.7 events. After background subtraction and analysis corrections, the fiducial cross-section of the process Pb + Pb (gamma gamma) -> Pb-(center dot) + Pb-(center dot) gamma gamma, for photon transverse energy E-T > 3 GeV, photon absolute pseudorapidity vertical bar eta vertical bar < 2.4, diphoton invariant mass greater than 6 GeV, diphoton transverse momentum lower than 2 GeV and diphoton acoplanarity below 0.01, is measured to be 70 +/- 24 (stat.) +/- 17 (syst.) nb, which is in agreement with the standard model predictions.
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