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1.
  • Ahrens, J., et al. (author)
  • Results from AMANDA
  • 2001
  • In: Proceedings, 9th International Workshop, Venice, Italy, March 6-9, 2001. Vol. 1, 2. ; , s. 569-580
  • Conference paper (peer-reviewed)
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2.
  • Andreasson, Björn, et al. (author)
  • Plasma erythropoietin concentrations in polycythaemia vera with special reference to myelosuppressive therapy.
  • 2000
  • In: Leukemia & lymphoma. - : Informa UK Limited. - 1042-8194 .- 1029-2403. ; 37:1-2, s. 189-95
  • Journal article (peer-reviewed)abstract
    • In 80 patients with polycythaemia vera (PV) a total of 108 venous blood samples were obtained and analysed for EDTA-plasma erythropoietin (EPO) concentration. At the time of study 21 of the PV patients were newly diagnosed and had prior to blood sampling neither received phlebotomy treatment nor therapy with myelosuppressive agents; these subjects had a mean plasma EPO concentration of 0.5+/-0.9 IU/L. Thirty-seven patients treated with phlebotomy only had a mean plasma EPO concentration of 2.5+/-2.9 IU/L. The mean plasma EPO concentrations for 26 patients treated with hydroxyurea, 13 patients treated with radiophosphorous and 11 patients given a combination of myelosuppressive agents were 8.9+/-8.0, 10.9+/-12.6 and 7.2+/-7.4 IU/L, respectively. Untreated patients and patients on phlebotomy only had significantly lower values for plasma EPO than patients on therapy with myelosuppressive drugs. This finding persisted also after a correction for differences in haemoglobin levels had been introduced. Thereby, the present results would suggest a difference in the EPO feedback system in untreated and phlebotomised PV patients compared to PV patients treated with myelosuppressive agents.
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3.
  • Berg, Sven, et al. (author)
  • Rheological properties of contaminated oil
  • 2000
  • In: Proceedings of the International Tribology Conference. - Tokyo : Japan Society of Tribologists. ; , s. 1239-1243
  • Conference paper (peer-reviewed)
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5.
  • Botner, Olga, et al. (author)
  • AMANDA: Status and Latest Results
  • 2004
  • In: 39th Rencontres De Moriond On Electroweak Interactions And Unified Theories, 21-28 Mar 2004, La Thuile, Aosta Valley, Italy.
  • Conference paper (other academic/artistic)
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8.
  • Botner, Olga, et al. (author)
  • Design and Status of IceCube
  • 2004
  • In: 10th Vienna Conference On Instrumentation, 16-21 February 2004, Vienna, Austria.
  • Conference paper (other academic/artistic)
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9.
  • Botner, Olga, et al. (author)
  • Exotic Particle Detection with the AMANDA Detector
  • 2003
  • In: Proceedings of the 23rd International Conference on Physics in Collision (PIC 2003), Zeuthen, Germany, 26-28 June 2003.
  • Conference paper (other academic/artistic)
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10.
  • Botner, Olga, et al. (author)
  • IceCube: A Multipurpose Neutrino Telescope
  • 2003
  • In: 3rd International Workshop for Comprehensive Study of the High Energy Universe - Toward Very H3rd International Workshop for Comprehensive Study of the High Energy Universe - Toward Very High Energy Particle Astronomy - (VHEPA-3), Tokyo, Japan, 20-22 March 2003igh Energy Particle Astronomy - (VHEPA-3), Tokyo, Japan, 20-22 March 2003.
  • Conference paper (other academic/artistic)
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11.
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12.
  • Botner, Olga, et al. (author)
  • IceTop: The Surface Component of IceCube
  • 2003
  • In: Proceedings of the 28th International Cosmic Ray Conference, Tsukuba, Japan, 31 July - 7 August 2003, HE 1.5, 1117-1120.
  • Conference paper (other academic/artistic)
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13.
  • Botner, Olga, et al. (author)
  • Latest Results of AMANDA
  • 2004
  • In: Proceedings of the International Europhysics Conference on High-Energy Physics (HEP 2003), 17-23 July 2003, Aachen, Germany.
  • Conference paper (other academic/artistic)
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18.
  • Botner, Olga, et al. (author)
  • Recent Results from the AMANDA II
  • 2003
  • In: 31st International Conference on High Energy Physics (ICHEP02), Amsterdam, Netherlands, 24-31 July 200. - 0444513434
  • Conference paper (other academic/artistic)
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20.
  • Botner, Olga, et al. (author)
  • Results from AMANDA
  • 2002
  • In: Mod. Phys. Lett.. ; A17, s. 2019-
  • Conference paper (other academic/artistic)
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21.
  • Botner, Olga, et al. (author)
  • Results from the AMANDA Detector
  • 2004
  • In: Acta Physica Polonica B35. ; , s. 1919-1931
  • Conference paper (other academic/artistic)
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22.
  • Botner, Olga, et al. (author)
  • Results from the AMANDA Neutrino Telescopes
  • 2003
  • In: Proceedings of the VLVnuT Workshop, "Technical Aspects of a Very Large Volume Neutrino Telescope in the Mediterranean Sea", NIKHEF, Amsterdam 5-8 October 2003.
  • Conference paper (other academic/artistic)
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23.
  • Botner, Olga, et al. (author)
  • Results from the AMANDA Telescope
  • 2003
  • In: XVI International Conference on Particles and Nuclei (PaNic02), Osaka, Japan, 30 September - 4 October 2002.
  • Conference paper (other academic/artistic)
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26.
  • Botner, Olga, et al. (author)
  • Simulation of Ice Cherenkov Detectors for IceTop
  • 2003
  • In: Proceedings of the 28th International Cosmic Ray Conference, Tsukuba, Japan, 31 July - 7 August 2003, HE 1.5, 965-968.
  • Conference paper (other academic/artistic)
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27.
  • Botner, Olga, et al. (author)
  • Status of the AMANDA Experiment
  • 2003
  • In: Incontro Nazionale di Astrofisica delle Alte Energie, Roma, Italy, 15-16 maggio 2003.
  • Conference paper (other academic/artistic)
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28.
  • Botner, Olga, et al. (author)
  • Status of the IceCube Neutrino Observatory
  • 2004
  • In: 2nd VERITAS Symposium on the Astrophysics of Extragalactic Sources, Chicago, USA, 24-26 April 2003.
  • Conference paper (other academic/artistic)
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29.
  • Botner, Olga, et al. (author)
  • The AMANDA Neutrino Telescope
  • 2004
  • In: International School Of Cosmic Ray Astrophysics: 14th Course: Neutrinos and Explosive Events In The Universe.
  • Conference paper (other academic/artistic)
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31.
  • Botner, Olga, et al. (author)
  • The IceCube High Energy Neutrino Telescope
  • 2003
  • In: Proceedings of the 28th International Cosmic Ray Conference, Tsukuba, Japan, 31 July - 7 August 2003, HE 2.3, 1369-1372.
  • Conference paper (other academic/artistic)
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32.
  • Botner, Olga, et al. (author)
  • The IceCube Neutrino Telescope
  • 2004
  • In: International Symposium on Cosmology and Particle Astrophysics (CosPA 2003), Taipei, Taiwan, 13-15 November 2003.
  • Conference paper (other academic/artistic)
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33.
  • Botner, Olga, et al. (author)
  • The IceCube Project
  • 2003
  • In: Proceedings of the VLVnuT Workshop, "Technical Aspects of a Very Large Volume Neutrino Telescope in the Mediterranean Sea", NIKHEF, Amsterdam 5-8 October 2003.
  • Conference paper (other academic/artistic)
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34.
  • Eriksson, Erland, et al. (author)
  • Electrical resistivity and conductivity of greases : an initial study
  • 2002
  • In: Lubrication Science. - : Wiley. - 0954-0075 .- 1557-6833. ; 15:1, s. 33-50
  • Journal article (peer-reviewed)abstract
    • Investigations of railway wagons fitted with rolling-element bearings have shown damage to the bearings from the passage of electric current. This also occurs in railway wagons without an electric energy consumption of their own, because of residual currents from electric locomotives. This phenomenon gives rise to technical, financial, and even safety problems. This paper reviews research in the field of rolling-element bearings exposed to electric currents. The paper also reports on an ongoing study undertaken to understand the mechanism of current flow and the role of lubricants in the associated damage, and to identify the possibilities of minimising bearing damage. The obvious solution to this problem is to use optimised greases, i.e., with high electrical conductivity and good lubricating ability. In the preliminary work reported here a number of greases for railway use were tested to determine their electrical conductivity in static and dynamic situations. These tests were performed using specially designed apparatus, and significant initial information about the electrical properties of greases has been obtained in this research, for example, that there is a correlation between the electrical conductance under static and dynamic conditions. All the greases tested showed comparatively high resistivity values, which could be one explanation for the bearing damage observed.
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36.
  • Flisberg, Per, et al. (author)
  • Apnea and bradypnea in patients receiving epidural bupivacaine-morphine for postoperative pain relief as assessed by a new monitoring method.
  • 2002
  • In: Journal of Clinical Anesthesia. - 1873-4529. ; 14:2, s. 129-134
  • Journal article (peer-reviewed)abstract
    • STUDY OBJECTIVE: To evaluate postoperative breathing patterns with a new monitoring device in patients given bupivacaine-morphine epidural analgesia. DESIGN: Open explorative study. SETTING: Inpatient anesthesia in a university hospital setting. PATIENTS: 15 ASA physical status I and II patients aged 28 to 87 years and scheduled for major abdominal surgery. INTERVENTIONS: All patients underwent abdominal surgery with epidural anesthesia combined with general anesthesia. Postoperatively, they continued with epidural analgesia consisting of bupivacaine and morphine. On the first postoperative night, the breathing pattern was studied with a new noninvasive monitoring device measuring respiratory frequency and apnea. Arterial blood gas analysis was performed in case of apnea or low respiratory frequency. MEASUREMENTS AND MAIN RESULTS: A total of 84 alarm events were registered in 11 patients. Twenty-one percent (18/84) of the alarms were associated with arterial carbon dioxide tension (PaCO2) levels greater than 48.8 mmHg. Three of the four patients with PaCO2 levels greater than 48.8 mmHg were older than 80 years of age. CONCLUSION: The tested noninvasive monitoring device may detect abnormal respiratory breathing patterns in patients at risk for respiratory depression during epidural analgesia with bupivacaine-morphine.
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37.
  • Håkansson, Anders, et al. (author)
  • A Systematic Evaluation of RT Methods for SME:s
  • 2004
  • In: Time-compression technologies, Europe : the magazine for fast and efficient design engineering teams. - 1467-1360. ; 12:4, s. 20-27
  • Journal article (peer-reviewed)
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38.
  • Johansson, Arne, et al. (author)
  • Preoperative ropivacaine infiltration in breast surgery
  • 2000
  • In: Acta Anaesthesiologica Scandinavica. - : Wiley. - 0001-5172. ; 44:9, s. 1093-1098
  • Journal article (peer-reviewed)abstract
    • Purpose: The aim of the study was to investigate whether preoperative infiltration with ropivacaine in conjunction with breast surgery improves postoperative pain management and attenuates postoperative nausea and vomiting. Method: Prospective, randomised, double-blind study, including 60 healthy women (ASA 1–2) allocated to one of two groups. Thirty patients were given 0.3 ml/kg saline in the operating field before surgery. Another 30 patients received a similar volume of ropivacaine 3.75 mg/ml. A visual analogue scale (0–100 mm) was used for evaluation of postoperative pain, nausea and vomiting. If the score was more than 30 mm at rest, the patients were given ketobemidone i.v. as treatment for postoperative pain, and dixyrazine i.v. against nausea and vomiting. The intra- and postoperative analgesic requirements and postoperative nausea and vomiting were registered. Results: The intraoperative fentanyl consumption was similar in the saline group 81±22 μg vs 76±28 μg; (ns) in the ropivacaine group. The postoperative 24-h ketobemidone consumption was also similar to those treated with ropivacaine (4.2±2.6 mg vs 4.2±4.3 mg; ns). Postoperative nausea and vomiting (PONV) occurred with similar frequencies in both groups. The 24-h dixyrazine consumption was the same in the two groups (2.1±2.7 mg in the saline group compared to 2.4±2.8 mg in the ropivacaine group; ns). After 6 h recovery, 41% of all patients had experienced nausea and 20% vomiting. Conclusion: We found no differences in postoperative pain management between 3.75 mg/ml ropivacaine and saline wound infiltration before breast surgery. The data show similar postoperative needs of analgesics and antiemetics with a similar frequency of PONV.
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39.
  • Lind, Monica, et al. (author)
  • Abnormal bone composition in female juvenile American alligators from a pesticide-polluted lake (Lake Apopka, Florida)
  • 2004
  • In: Journal of Environmental Health Perspectives. - : Environmental Health Perspectives. - 0091-6765 .- 1552-9924. ; 112:3, s. 359-362
  • Journal article (peer-reviewed)abstract
    • Reproductive disorders have been found in pesticide-exposed alligators living in Lake Apopka, Florida (USA). These disorders have been hypothesized to be caused by exposure to endocrine- disruptive estrogen-like contaminants. The aim of this study was to expand our analysis beyond previous studies by investigating whether bone tissue, known to be affected by sex steroid hormones, is a potential target of endocrine disruptors. Long bones from 16 juvenile female alligators from Lake Apopka (pesticide-contaminated lake) and Lake Woodruff (control lake) were evaluated by peripheral quantitative computed tomography. We observed significant differences in bone composition, with female alligators from the contaminated lake having greater trabecular bone mineral density (BMD), total BMD, and trabecular mineral content compared with females from the control lake (p < 0.05). Increased trabecular and total BMD measurements suggest that juvenile female alligators from Lake Apopka were exposed to contaminants that created an internal environment more estrogenic than that normally observed. This estrogenic environment could be caused by both natural and anthropogenic compounds. Effects on BMD indicate interference with bone homeostasis. We hypothesize that contaminants present in the lake inhibit the natural and continuous resorption of bone tissue, resulting in increased bone mass. Although this is the only study performed to date examining effects of environmental estrogenic compounds on alligator bones, it supports previous laboratory-based studies in rodents. Further, this study is important in demonstrating that the alterations in morphology and physiology induced in free-ranging individuals living in environments contaminated with endocrine-active compounds are not limited to a few systems or tissues; rather, effects can be observed in many tissues affected by these hormones.
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40.
  • Lindström, Jan, et al. (author)
  • From arctic lemmings to adaptive dynamics: Charles Elton's legacy in population ecology
  • 2001
  • In: Biological Reviews. - 1469-185X. ; 76:1, s. 129-158
  • Research review (peer-reviewed)abstract
    • We shall examine the impact of Charles S. Eltons 1924 article on periodic fluctuations in animal populations on the development of modern population ecology. We argue that his impact has been substantial and that during the past 75 years of research on multi-annual periodic fluctuations in numbers of voles, lemmings, hares, lynx and game animals he has contributed much to the contemporary understanding of the causes and consequences of population regulation. Elton was convinced that the cause of the regular fluctuations was climatic variation. To support this conclusion, he examined long-term population data then available. Despite his firm belief in a climatic cause of the self-repeating periodic dynamics which many species display, Elton was insightful and far-sighted enough to outline many of the other hypotheses since put forward as an explanation for the enigmatic long-term dynamics of some animal populations. An interesting, but largely neglected aspect in Eltons paper is that it ends with speculation regarding the evolutionary consequences of periodic population fluctuations. The modern understanding of these issues will also be scrutinised here. In population ecology, Eltons 1924 paper has spawned a whole industry of research on populations displaying multi-annual periodicity. Despite the efforts of numerous research teams and individuals focusing on the origins of multi-annual population cycles, and despite the early availability of different explanatory hypotheses, we are still lacking rigorous tests of some of these hypotheses and, consequently, a consensus of the causes of periodic fluctuations in animal populations. Although Elton would have been happy to see so much effort spent on cyclic populations, we also argue that it is unfortunate if this focus on a special case of population dynamics should distract our attention from more general problems in population and community dynamics.
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41.
  • Lundberg, Jan, et al. (author)
  • A new method for determining the mechanical stability of lubricating greases
  • 2000
  • In: Tribology International. - 0301-679X .- 1879-2464. ; 33:3-4, s. 217-223
  • Journal article (peer-reviewed)abstract
    • Mechanical stability is of central importance when dealing with the long-term service-length of grease-lubricated roller bearings. Poor stability will lead to consistency degradation of the grease, because of mechanical forces between the rolling parts of the bearing. The result can be leakage of grease through seals, or at worst a total failure of the bearing. The present investigation was initiated because present-day methods for prediction of mechanical stability show weak correlation with real service-length. The aim of the project was to develop a useful alternative. In order to fulfil this, both field tests and laboratory tests were carried out. In the field tests, nine different commercial greases were examined in the wheel bearings of five ore waggons, used for transporting ore by railroad from the Kiruna Mine in northern Sweden to Narvik in northern Norway for shipping to foreign markets. The test ore waggons travelled a distance of about 300,000 km during a period of 3 years. Small samples of greases were taken, on eight different occasions, for consistency testing. After the end of the test period, the damage on the bearings was also studied. In the laboratory tests, new undestroyed greases of the same brand as in the field tests were examined using conventional methods, such as the V2F, the Roll Stability Test and the Grease Worker. Comparisons between the field tests and these laboratory tests indicate poor correlation. In addition to these conventional methods, the relevance of the shear strength of the greases to the prediction of the mechanical stability was also tested. The shear stress τL depends on the applied pressure p, thus τL=τO+γ·p where τO is the shear stress at atmospheric pressure, γ is a property of the lubricant in the same way as viscosity or density. It was found that γ correlates well with the mechanical stability in service. Increased γ values lead to a decrease in the mechanical stability. One reasonable explanation is that high γ values correspond to high shear stresses in the grease, and thus severe conditions for the thickener.
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42.
  • Lundberg, Jan (author)
  • Grease lubrication of roller bearings in railway waggons. Part 1: field tests and systematic evaluation to determine the optimal greases
  • 2000
  • In: Industrial Lubrication and Tribology. - : Emerald. - 0036-8792 .- 1758-5775. ; 52:1, s. 36-43
  • Journal article (peer-reviewed)abstract
    • Describes a comprehensive field test to determine the best grease for spherical roller bearings in railway waggon wheels and increase the knowledge of grease lubrication. Nine different fully-formulated commercial greases were examined in the wheel bearings of five ore waggons, used for transporting ore commercially by railroad from the Kiruna Mine in northern Sweden to Narvik in northern Norway for shipping to foreign markets. After the end of the test period, the wear and electrical damage, as well as the rust on the bearings, were also studied. In order to find out the optimum grease for this application, draws up a specification of requirements and uses a systematic approach to development of an evaluation method that could be applied to greases in actual service.
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43.
  • Lundberg, Jan, et al. (author)
  • Grease-lubrication of roller bearings in railway waggons. Part 2 : Laboratory tests and selection of proper test methods
  • 2000
  • In: Industrial Lubrication and Tribology. - : Emerald. - 0036-8792 .- 1758-5775. ; 52:2, s. 76-86
  • Journal article (peer-reviewed)abstract
    • New, undestroyed greases of the same brands as those used in a field test, described in Part 1, were examined using conventional methods, such as the SKF V2F test, the roll stability test (ASTM D-1831), the Grease Worker (ASTM D-217), the torque test (ASTM 1478-91), bleeding measurements ( IP 121), yield stress measurements, the 4-ball test (ASTM D 2266-86), base oil viscosity measurements, thickener content and the cone penetration test (ASTM D217-88). The greases have also been tested with several new test methods developed at the University. A specification for relevant testing methods was drawn up and the connections between the tested parameters were investigated. It was found that the mechanical stability could be predicted with a combination of ASTM D-1831 and the limiting shear stress coefficient ?. This coefficient is capable of predicting wear. It was found that the bearing temperature could be predicted by using the base oil viscosity.
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44.
  • Lundberg, Jan, et al. (author)
  • Handbook for grease applications
  • 2000
  • In: Industrial Lubrication and Tribology. - : Emerald. - 0036-8792 .- 1758-5775. ; 52:5, s. 221-232
  • Journal article (peer-reviewed)abstract
    • The process of finding the ultimate grease is described in this report using an example from railway applications. This example includes steps such as a requirement list, field tests, laboratory tests and an evaluation method. The example deals with the problems discovered in a field test performed to determine the best grease for tapered roller bearings in railway wagon wheels and to increase the knowledge of grease lubrication. Seven different fully formulated commercial greases were examined in the wheel bearings of one ore wagon, used for transporting ore commercially by railway from the Kiruna Mine in northern Sweden to Narvik in northern Norway for shipping to foreign markets. The steps performed in this study are recommended in all problems associated.
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45.
  • Lundberg, Staffan, et al. (author)
  • Hippocampal region asymmetry assessed by 1H-MRS in rolandic epilepsy
  • 2003
  • In: Epilepsia. - : Wiley. - 0013-9580 .- 1528-1167. ; 44:2, s. 205-210
  • Journal article (peer-reviewed)abstract
    • PURPOSE: In a previous study, we reported hippocampal abnormalities on magnetic resonance imaging (MRI) in six of 18 children with rolandic epilepsy (RE). In this study, metabolic changes were analyzed in the hippocampal region with proton magnetic resonance spectroscopy (1H-MRS). METHODS: In 13 children with electroclinically typical RE and 15 healthy controls, 1H-MRS results of both hippocampal regions were analyzed. The voxels, 2 x 2 x 4-cm each, were placed to include the head and body of the hippocampus. A PRESS sequence with TR 2,000 ms and TE 32 ms was used. Total N-acetylaspartate (tNAA), glutamine and glutamate (Glx), and choline compounds (tCho) were related to total creatine (tCr), and asymmetry indices (AIs) were calculated. MRI was performed in all 13 patients and in 13 controls. RESULTS: The tNAA/tCr AI of the hippocampal region was significantly higher in children with RE than in control children (z = 4.49; p < 0.001). The AIs of Glx/tCr and tCho/tCr did not show a significant difference between the groups. Lateralization of the interictal epileptiform activity corresponded with the lower tNAA/tCr ratio in 10 of 13 patients. MRI revealed a hippocampal asymmetry in four of 13 in the RE group, three of them showed concordance between the lateralization of the lower tNAA/tCr ratio and the smaller hippocampus. In the control group, a subtle asymmetry in four of 13 children was found. CONCLUSIONS: A significant asymmetry of the hippocampal regions, measured by tNAA/tCr ratios, indicates an abnormal neuronal function in children with RE.
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  • Result 1-47 of 47

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