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- Mellgren, Karin, 1962, et al.
(författare)
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Effect of nitric oxide gas on platelets during open heart operations.
- 1998
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Ingår i: The Annals of thoracic surgery. - 0003-4975. ; 65:5, s. 1335-41
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Tidskriftsartikel (refereegranskat)abstract
- The increased bleeding tendency observed after cardiopulmonary bypass is caused in part by thrombocytopenia and impaired platelet function induced by the procedure. Previous in vitro studies have shown that nitric oxide (NO) added to the oxygenator sweep gas reduces platelet activation during experimental perfusion. We evaluated the effect of 40 ppm of NO, added to the oxygenator sweep gas, on platelet consumption and activation in patients undergoing cardiopulmonary bypass.
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- Mellgren, Karin, 1962, et al.
(författare)
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Nitric oxide in the oxygenator sweep gas reduces platelet activation during experimental perfusion.
- 1996
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Ingår i: The Annals of thoracic surgery. - 0003-4975. ; 61:4, s. 1194-8
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Tidskriftsartikel (refereegranskat)abstract
- Hemorrhage is a major complication experienced in 10% to 35% of neonates treated with extracorporeal life support (ECLS). The increased bleeding tendency is partly due to an ECLS-induced thrombocytopenia and impaired platelet function. In the present study, we evaluated the effect of nitric oxide on the ECLS-induced platelet consumption and activation.
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- Mellgren, Karin, 1962, et al.
(författare)
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Platelet activation and degradation in an experimental extracorporeal system. A comparison between a silicone membrane and a hollow-fibre oxygenator.
- 1996
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Ingår i: Perfusion. - 0267-6591. ; 11:5, s. 383-8
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Tidskriftsartikel (refereegranskat)abstract
- Blood platelets are rapidly activated in contact with biomaterials and, therefore, can be used as markers of the biocompatibility of various components in an extracorporeal system. In the present work two different oxygenators, one membrane oxygenator (Avecor) and one hollow-fibre oxygenator ("Lilliput', Dideco) were compared. Complete in vitro extracorporeal membrane oxygenation circuits were perfused with fresh, heparinized human blood for 24 h. Eight experiments were performed with the hollow-fibre oxygenator and five experiments with the membrane oxygenator. Blood gases, electrolytes, glucose and haematocrit were kept within physiological limits. Platelet count, plasma concentration of beta-thromboglobulin, platelet serotonin content, platelet membrane glycoprotein lb and its degradation product glycocalicin, as well as plasma haemoglobin concentration were assayed. As regards most of these variables, significant differences in favour of the hollow-fibre oxygenator were observed.
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- Bremmer, S, et al.
(författare)
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Defaeco-peritoneography in the diagnosis of rectal intussusception and rectal prolapse
- 1997
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Ingår i: Acta radiologica (Stockholm, Sweden : 1987). - : SAGE Publications. - 0284-1851 .- 1600-0455. ; 38:44 Pt 1, s. 578-583
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: The aim of the present study was to evaluate the use of defaeco-peritone-ography in diagnosing rectal intussusception as distinct from mucosal folds in the rectum, and rectal prolapse as distinct from mucosal prolapse. Material and Methods: Fifty-seven patients with defaecation disorders were examined by means of defaeco-peritoneography. Results: Twenty-three patients had rectal intussusception and 7 patients had rectal prolapse at defaeco-peritoneography. All these patients had a rectal peritoneocele in the serosal ring-pocket of the rectal intussusception or in the rectal prolapse. Twenty-seven patients had neither rectal intussusception nor rectal prolapse and none of these patients had a rectal peritoneocele. Conclusion: The present study demonstrated that only patients with a rectal intussusception or rectal prolapse have a rectal peritoneocele. Defaeco-peritoneography therefore offers correct diagnosis of rectal intussusception as distinct from mucosal folds in the rectum, and of rectal prolapse as distinct from mucosal prolapse.
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- Bremmer, S, et al.
(författare)
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Peritoneocele and enterocele. Formation and transformation during rectal evacuation as studied by means of defaeco-peritoneography
- 1998
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Ingår i: Acta radiologica (Stockholm, Sweden : 1987). - : SAGE Publications. - 0284-1851 .- 1600-0455. ; 39:2, s. 167-175
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: to study, by means of defaeco-peritoneography, the formation and transformation of the peritoneocele, with and without an enterocele, during rectal evacuation Material and Methods: Forty-six patients with a peritoneocele at defaeco-peritoneography were selected for the study, and examined at three different stages: 1) at the start with a contrast-filled rectum; 2) at maximum straining; and 3) at rest after rectal evacuation Results: Fourteen patients had a peritoneocele at the start. These peritoneoceles were largest at maximum straining and were all still present at rest after rectal evacuation. in 32 patients defaeco-peritoneography was regarded as normal at the start. at maximum straining these patients developed a peritoneocele and 20 of these were still present after rectal evacuation. No enterocele was seen at the start. at maximum straining 21 patients developed an enterocele and 15 of these were still present after rectal evacuation. Liquid in varying amounts was found in the peritoneoceles Conclusion: the present study demonstrated that peritoneoceles were present at different stages of the defaeco-peritoneographic investigations. Peritoneoceles were most frequent and largest at maximum straining. an enterocele was present in half of the peritoneoceles at maximum straining, but never at the start. Liquid was often present in the peritoneoceles
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- MELLGREN, A
(författare)
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Diagnosis and treatment of constipation
- 1995
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Ingår i: The European journal of surgery = Acta chirurgica. - 1102-4151. ; 161:9, s. 623-634
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Tidskriftsartikel (refereegranskat)
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