| 1. |
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| 2. |
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| 3. |
- Forzati, Marco, et al.
(författare)
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40-gb/s field transmission through 540 km ssmf using the aprz modulation format
- 2005
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Ingår i: Optics InfoBase Conference Papers. - : Optical Society of America. - 1557527849 - 9781557527844
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Konferensbidrag (refereegranskat)abstract
- We report the first field transmission experiment using the APRZ modulation format for 40-Gb/s transmission through 540 km SSMF, which confirms the improved nonlinear tolerance of APRZ. The optimum phase-modulation amplitude in this experiment is p/2.
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| 4. |
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| 5. |
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| 6. |
- Holst, Anders, et al.
(författare)
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Intertwining operators in inverse scattering
- 2004
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Ingår i: New Analytic and Geometric Methods in Inverse Problems: Lectures Given at the Ems Summer School and Conference Held in Edinburgh, Scotland 2000. - 3540406824 ; , s. 51-92
-
Konferensbidrag (refereegranskat)abstract
- In these notes we are going to present a technique which is a multi-dimensional analogue of some methods which are nowadays standard inscattering theory on the real line for the Schrödinger operator. These methods are based on the construction of operators intertwining the Schrödinger operator with the free operator, obtained when the potential term is removed. The multi-dimensional technique using intertwining operators as a tool for the study of Schrödinger operators has its origin in a famous paper by L. D. Faddeev. Various extensions of this technique have been developed during the last years by the second author of this article.
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| 7. |
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| 8. |
- Malinowsky, Camilla, et al.
(författare)
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Differences in the use of everyday technology among persons with MCI, SCI and older adults without known cognitive impairment
- 2017
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Ingår i: International psychogeriatrics. - : Cambridge University Press. - 1041-6102 .- 1741-203X. ; 29:7, s. 1193-1200
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Tidskriftsartikel (refereegranskat)abstract
- Background: To use valid subjective reports sensible to cognitive decline is vital to identify very early signs of dementia development. Use of everyday technology (ET) has been shown to be sensitive to differentiate adults with mild cognitive impairment (MCI) from controls, but the group with subjective cognitive impairment (SCI) has not yet been examined. This study aims to investigate and compare self-perceived ability in ET use and number of ETs reported as actually used in a sample of older adults with SCI, MCI, and older adults with no known cognitive impairment, i.e. controls.Methods: Older adults with MCI (n = 29), SCI ( n = 26), and controls (n = 30) were interviewed with the short version of the Everyday Technology Use Questionnaire (S-ETUQ) to capture self-perceived ability in ET use and number of ETs used. To generate individual measures of ability to use ET, Rasch analysis was used. The measures were then compared group-wise using ANCOVA. The numbers of ETs used were compared group-wise with ANOVA.Results: Controls versus SCI and MCI differed significantly regarding ETs reported as used, but not SCI versus MCI. Similarly, in ability to use ET, controls versus SCI and MCI differed significantly but not SCI versus MCI.Conclusions: The significantly lower numbers of ETs reported as actually used and the lower ability in SCI and MCI groups compared to controls suggest that ET use is affected already in very minor cognitive decline. This indicates that self-reported ET use based on the S-ETUQ is sensitive to detect changes already in SCI.
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| 9. |
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| 10. |
- Tornberg, Åsa B.B., et al.
(författare)
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Reduced Neuromuscular Performance in Amenorrheic Elite Endurance Athletes
- 2017
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Ingår i: Medicine & Science in Sports & Exercise. - : Lippincott Williams & Wilkins. - 0195-9131 .- 1530-0315. ; 49:12, s. 2478-2485
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Tidskriftsartikel (refereegranskat)abstract
- Introduction Secondary functional hypothalamic amenorrhea (SFHA) is common among female athletes, especially in weight-sensitive sports. The aim of this study was to investigate the link between SFHA and neuromuscular performance in elite endurance athletes. Methods Sixteen eumenorrheic (EUM) and 14 SFHA athletes from national teams and competitive clubs participated. Methods included gynecological examination, body composition (dual-energy x-ray absorptiometry), resting metabolic rate and work efficiency, exercise capacity, knee muscular strength (KMS) and knee muscular endurance (KME), reaction time (RT), blood sampling performed on the third to fifth days of the menstrual cycle, and 7-d assessment of energy availability. Results SFHA athletes had lower estrogen (0.12 0.03 vs 0.17 +/- 0.09 nmolL(-1), P < 0.05), triiodothyronine (T-3) (1.4 +/- 0.2 vs 1.7 +/- 0.3 nmolL(-1), P < 0.01), and blood glucose (3.8 +/- 0.3 vs 4.4 +/- 0.3 mmolL(-1), P < 0.001) but higher cortisol levels (564 +/- 111 vs 400 +/- 140 nmolL(-1), P < 0.05) compared with EUM athletes. SFHA had a lower body weight (55.0 +/- 5.8 vs 60.6 +/- 7.1 kg, P < 0.05), but no difference in exercise capacity between groups was found (56.4 +/- 5.8 vs 54.0 +/- 6.3 mL O(2)min(-1)kg(-1)). RT was 7% longer, and KMS and KME were 11% and 20% lower compared with EUM athletes. RT was negatively associated with glucose (r = -0.40, P < 0.05), T-3 (r = -0.37, P < 0.05), and estrogen (r = -0.43, P < 0.05), but positively associated with cortisol (r = 0.38, P < 0.05). KMS and KME correlated with fat-free mass in the tested leg (FFMleg; r = 0.52, P < 0.001; r = 0.58, P < 0.001) but were negatively associated with cortisol (r = -0.42, P < 0.05; r = -0.59, P < 0.001). FFMleg explained the differences in KMS, while reproductive function and FFMleg independently explained the variability in KME. Conclusions We found lower neuromuscular performance among SFHA compared with EUM athletes linked to a lower FFMleg, glucose, estrogen, T-3, and elevated cortisol levels.
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| 11. |
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| 12. |
- af Wåhlberg, Anders, 1965-
(författare)
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The Prediction of Traffic Accident Involvement from Driving Behavior
- 2006
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The aim of the studies was to predict individual traffic accident involvement by the quantification of driving style in terms of speed changes, using bus drivers as subjects. An accident database was constructed from the archives of the bus company whose drivers were used as subjects. The dependent variable was also discussed regarding whether responsibility for crashes should be included, and what time period to use for optimal prediction. A new theory was constructed about how accidents are caused by driver behavior, more specifically the control movements of the driver, i.e. all actions taken which influence the relative motion of the vehicle in a level plane when v>0. This theory states that all traffic safety related behavior can be measured as celerations (change of speed of the vehicle in any direction of a level plane) and summed. This theoretical total sum is a measure of a person's liability to cause accidents over the same time period within a homogenous traffic environment and a similarly homogenous driving population. Empirically, the theory predicts a positive correlation between mean driver celeration behavior and accident record. The theory was tested in three empirical studies. The first tested equipment and methods, the second studied the question whether driver celeration behavior is stable over time. Celeration behavior turned out to be rather variable between days, and repeated measurements were therefore needed to stabilize the measure. In the third study, a much larger amount of data brought out correlations of sizes sufficient to lend some credibility to the theory. However, the predictive power did not extend beyond two years of time. The reported results would seem to imply that the celeration variable can predict accident involvement (at least for bus drivers), and is practical to use, as it is easily and objectively measured and semi-stable over time.
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| 13. |
- Andersson, Ulrika, et al.
(författare)
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A comprehensive study of the association between the EGFR and ERBB2 genes and glioma risk
- 2010
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Ingår i: Acta Oncologica. - : Informa Healthcare. - 0284-186X .- 1651-226X. ; 12, s. 17-17
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Tidskriftsartikel (refereegranskat)abstract
- Glioma is the most common type of adult brain tumor and glioblastoma, its most aggressive form, has a dismal prognosis. Receptor tyrosine kinases such as the epidermal growth factor receptor (EGFR, ERBB2, ERBB3, ERBB4) family, and the vascular endothelial growth factor receptor (VEGFR), play a central role in tumor progression. We investigated the genetic variants of EGFR, ERBB2, VEGFR and their ligands, EGF and VEGF on glioma and glioblastoma risk. In addition, we evaluated the association of genetic variants of a newly discovered family of genes known to interact with EGFR: LRIG2 and LRIG3 with glioma and glioblastoma risk. Methods. We analyzed 191 tag single nucleotide polymorphisms (SNPs) capturing all common genetic variation of EGF, EGFR, ERBB2, LRIG2, LRIG3, VEGF and VEGFR2 genes. Material from four case-control studies with 725 glioma patients (329 of who were glioblastoma patients) and their 1 610 controls was used. Haplotype analyses were conducted using SAS/Genetics software. Results. Fourteen of the SNPs were significantly associated with glioma risk at p< 0.05, and 17 of the SNPs were significantly associated with glioblastoma risk at p< 0.05. In addition, we found that one EGFR haplotype was related to increased glioblastoma risk at p=0.009, Odds Ratio [OR] = 1.67 (95% confidence interval (CI): 1.14, 2.45). The Bonferroni correction made all p-values non-significant. One SNP, rs4947986 next to the intron/exon boundary of exon 7 in EGFR, was validated in an independent data set of 713 glioblastoma and 2 236 controls, [OR] = 1.42 (95% CI: 1.06,1.91). Discussion. Previous studies show that regulation of the EGFR pathway plays a role in glioma progression but the present study is the first to find that certain genotypes of the EGFR gene may be related to glioblastoma risk. Further studies are required to reinvestigate these findings and evaluate the functional significance.
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| 14. |
- Anveskog, L., et al.
(författare)
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Development of Activities - Standard Application Packages according SIV to help you make better use of standard application packages in your organization : Verksamhetsutveckling - Standardsystem enligt SIV för att du skall kunna utnyttja standardsystem bättre i din verksamhet
- 1986
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The report is published in an English and Swedish version.Rapporten finns utgiven på svenska och engelska. ------------------------------------------------There is a need for a systematic way of working when planning for standard application packages in organizations. We have tried to develop a method for this field - the SIV method (Standard Application Packages in Organizations, in Swedish: Standardsystem I Verksamheter). The SIV method takes the customer's situation as a starting point - a customer view. Furthermore, occasions have been described where a dialogue between the customer and the vendor is necessary, e.g. demonstrations and negotiations. The SIV method gives a survey of the field with emphasis on adaptation of activities and standard application packages to each other.This report is focusing on "adaptation" of standard application packages. A similar report has been done for "choice" of standard application packages.------------------------------------------------ Det finns behov av ett systematiskt arbetssätt vid planering av standardsystem för verksamheter. Vi har försökt utveckla en metodik för detta område - SIV (Standardsystem I Verksamheter). SIV-metodiken tar utgångspunkt i kundens situation - ett kundperspektiv.Vidare anges tillfällen när det behövs en dialog mellan kund och leverantör, t.ex. demonstrationer och förhandlingar. SIV-metodiken ger en översikt av området med betoning på anpassning av verksamhet och standardystem mot varandra.Denna rapport behandlar "anapssning" av standardsystem. En liknande rapport har tagits fram för "val" av standardystem.------------------------------------------------
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| 15. |
- Anveskog, L., et al.
(författare)
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Verksamhetsutveckling - Att anpassa standardsystem
- 1983
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Bok (refereegranskat)abstract
- Syftet med standardsystem är att tjäna tid och pengar. Ett standardsystem kan även ge nya möjligheter att effektivisera en verksamhet. Finns det några problem vid anskaffning av standardsystemet? Ja, alltför ofta väljs standardsystem på ett för dåligt underlag om verksamhetens krav och behov. Sedan underskattar man resurserna för anpassning av standardsystem och verksamhet till varandra.Denna bok behandlar en metod för att anpassa standardysstem i ett företags verksamhet (SIV-metoden). Boken innehåller praktikfall från Alfa-Laval och Philips som exempel på metodanvändningen. Boken vänder sig till personer som arbetar med att förändra standardsystem och det egna verksamhetsområdet mot varandra med de konsekvenser detta kan innebära.Ibland behöver vi göra ett förval bland urvalet av standardsystem på marknaden. En metod för detta presenteras i boken: " Verksamhetsutveckling - Att välja standardsystem" (Studenlitteratur, 1984) som kan ses som ett komplement till denna bok.Boken var förpublicerad som V-rapport V-4201, Institutet för Verksamhetsutveckling (Institut V) vid Handelshögskolan i Stockholm (1982-02-26)
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| 16. |
- Athanassiadis, Dimitris, et al.
(författare)
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HARVESTING POTENTIAL AND PROCUREMENT COSTS OF LOGGING RESIDUES IN SWEDEN
- 2009
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The aim of this study was (i) to provide an estimation of the potential amount of logging residues (branches, tops and stumps with attached root system) that will be produced in Sweden (thinning and regeneration fellings) during the next decade (2010-2019) and (ii) calculate the costs for harvesting the residue, comminute it and bring it to the end user. Depending on the level of ecological, technical and economical restrictions the potential amount of slash (branches, tops and stumps) in regeneration fellings varied from 3.2 to 7.4 Mt OD annually while the potential amount (Mt OD) of stumps varied from 4.2 to 11.7 annually. The corresponding annual figures in thinning for slash and stumps were 1.7 to 3.9 and 1.8 to 5.7 Mt OD annually, respectively. 80% of the potential amount of slash and stumps at level 3 of ecological, technical and economical restrictions in regeneration fellings would be available for 85 EUR/ODT and 110 EUR/ODT, respectively
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| 17. |
- Athanassiadis, Dimitris, et al.
(författare)
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Marginalkostnader för skörd av grot och stubbar från föryngringsavverkningar i Sverige
- 2009
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Kostnaden för att ta ut grot och stubbar från föryngringsavverkningar i Sverige har uppskattats och redovisas i form av marginalkostnadskurvor. Beräkningarna baseras på den mängd grot och stubbar som faller ut till följd av föryngringsavverkningar som utförs i referensscenariot i SKA-VB 08 för perioden 2010 - 2019. De potentialer som använts är efter avdrag för ekologiska, tekniska och ekonomiska restriktioner, dvs. nivå 3 i SKA-VB 08. Kostnaderna för uttag av grot och stubbar har beräknats för de maskinsystem som är vanligast förekommande i Sverige och Finland idag. Ersättning till markägare, administrationsomkostnader och kostnader för skörd, sönderdelning, maskinflyttningar och transport av grot och stubbar är de kostnadsposter som ingår i beräkningarna. Grot kan tas ut till en lägre kostnad än stubbar vilket leder till att marginalkostnadskurvan för grot startar på en lägre nivå än marginalkostnadskurvan för stubbar; 600 kr/ton TS för grot respektive 800 kr/ton TS för stubbar. Om kostnaden får öka från 770 till 920 kr/ton TS kan tillvaratagandet av grot öka från dagens ca 2 till 2,9 Mton TS, dvs. 90 % av den tillgängliga potentialen som är 3,2 Mton TS. Först vid en kostnad på 850 kr/ton TS trädbränsle uppgår andelen stubbar till 10 % av sortimentsfördelningen. Vid en kostnad på 1 100 kr/ton TS är sortimentsfördelningen så gott som lika för grot och stubbar. Om 2,5 Mton TS (60 %) av tillgänglig potential stubbar i nuläget ska bli aktuella för skörd blir uttagskostnaden upp till 1 000 kr/ton TS. Omräkningstalet 1 ton TS = 4,9 MWh har använts vid omvandling mellan massa och energi. Detta värde anger mängden energi som kan avges som värme vid förbränning av skogsbränsle med en fukthalt på 40 % när vattnets ångbildningsenergi inte utnyttjas. Om prestationen för de maskiner som ingår i stubbsystemet ökar med 15 % så kan man få ut samma mängd vid 920 kr/ton TS. Kostnadsfördelningen visar att transportkostnaderna är den viktigaste kostnadsposten, speciellt när det gäller små avverkningstrakter, belägna långt från tätort
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| 18. |
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| 19. |
- Axelsson, Karin, 1968-, et al.
(författare)
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Communication Analysis of Public Forms : Discovering Multi-functional Purposes in Citizen and Government Communication
- 2007
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Ingår i: International Journal of Public Information Systems. - Sundsvall : MidSweden University. - 1653-4360. ; :3, s. 161-181
-
Tidskriftsartikel (refereegranskat)abstract
- This paper adopts a communication perspective on forms in public e-services. This perspective emphasizes that the main purpose of such forms is to facilitate communication between citizens and government agencies. The form is perceived as a tool for performing communicative actions. A communication analysis (CA) method, originally developed for systems requirements engineering, is applied on a public form; i.e. the medical certificate used in connection with a citizen’s application for a provisional driving license in Sweden. The CA method consists of a set of questions related tothree communicative categories; conditions, actions, and consequences. The CA method is used in order to explore the communicative roles of forms in public e-services. As a result of the communication analysis four multi-functional purposes of citizen and government agency communication are discovered. These purposes contribute to the understanding and evaluation of forms in public e-services. The communicative roles, and their multi-functional purposes, are important design features to focus in the development of e-services and electronic forms. Besides these findings, another outcomeis that the CA method has been tested in an e-government context. The communication perspective, as well as the CA method, contribute with useful insights in this context.
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| 20. |
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| 21. |
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| 22. |
- Baard, Patrik, 1981-, et al.
(författare)
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Justice in energy transition scenarios : Perspectives from Swedish energy politics
- 2023
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Ingår i: Etikk i praksis. - : Norwegian University of Science and Technology (NTNU) Library. - 1890-3991 .- 1890-4009.
-
Tidskriftsartikel (refereegranskat)abstract
- In this article we justify why justice ought to be considered in scenarios of energy transitions, stipulate what dimensions should reasonably be considered, and investigate whether such considerations are taken in Swedish parliamentary debates on energy policies. Through interviews we investigated how Swedish parliamentary politicians think through justice in energy transitions, providing a practical perspective. We conclude that while there is some overlap between minimal conditions for energy justice and the issues brought forward by Swedish politicians,several issues are omitted. Examples include procedural justice and recognizing Sámi interests. On the other hand, principles of energy justice omit economic issues, which are however often brought up by respondents. It can be argued that justice issues, and not only the technical and economic issues that currently dominate the political debate, should be considered in energy transitions. It is therefore unfortunate that questions about justice are not adequately recognized by Swedish members of parliament, as outlined here by interview results. Stronger conclusions would require more empirical work, but the article points out several discrepancies between the topics discussed in the research literature on energy policies, and the topics discussed by elected parliamentarians having a specific focus on energy policies.
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| 23. |
- Baard, Patrik, 1981-, et al.
(författare)
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Max Power: Implementing the Capabilities Approach to Identify Thresholds and Ceilings in Energy Justice
- 2022
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Ingår i: Science and Engineering Ethics. - : Springer. - 1353-3452 .- 1471-5546. ; 28:1
-
Tidskriftsartikel (refereegranskat)abstract
- In this paper, we apply the capabilities approach-with the addition of capability ceilings-to energy justice. We argue that, to ensure energy justice, energy policies and scenarios should consider enabling not only minimal capability thresholds but also maximum capability ceilings. It is permissible, perhaps even morally required, to limit the capabilities of those above the threshold if it is necessary for enabling those below the threshold to reach the level required by justice. We make a distinction between tragic and non-tragic conflicts of capabilities: tragic conflicts are instances when one cannot raise an agent's capabilities above the threshold that justice requires without pushing someone else below the threshold or restricting someone from reaching the threshold. In contrast, a non-tragic choice is when increasing someone above the threshold required by justice does not entail pushing someone else's capabilities below the threshold. We utilise this framework to discuss energy justice and emissions of greenhouse gases. Drawing on the relation between points on the human development index and levels of energy consumption, we conclude that non-tragic mitigation policies now are highly preferable to tragic policies later.
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| 24. |
- Beltita, Ingrid, et al.
(författare)
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Analysis of the Quadratic Term in the Backscattering Transformation
- 2009
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Ingår i: Mathematica Scandinavica. - 0025-5521. ; 105:2, s. 218-234
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Tidskriftsartikel (refereegranskat)abstract
- The quadratic term in the Taylor expansion at the origin of the backscattering transformation in odd dimensions n >= 3 gives rise to a symmetric bilinear operator B-2 on C-0(infinity)(R-n) x C-0(infinity)(R-n). In this paper we prove that B-2 extends to certain Sobolev spaces with weights and show that it improves both regularity and decay.
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| 25. |
- Beltita, Ingrid, et al.
(författare)
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Local Smoothing for the Backscattering Transform
- 2009
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Ingår i: Communications in Partial Differential Equations. - : Informa UK Limited. - 0360-5302 .- 1532-4133. ; 34:3, s. 233-256
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Tidskriftsartikel (refereegranskat)abstract
- An analysis of the backscattering data for the Schrodinger operator in odd dimensions n3 motivates the introduction of the backscattering transform [image omitted]. This is an entire analytic mapping and we write [image omitted] where BNv is the Nth order term in the power series expansion at v=0. In this paper we study estimates for BNv in H(s) spaces, and prove that Bv is entire analytic in vH(s)E' when s(n-3)/2.
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| 26. |
- Beltita, Ingrid, et al.
(författare)
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The quadratic contribution to the backscattering transform in the rotation invariant case
- 2010
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Ingår i: Inverse Problems and Imaging. - : American Institute of Mathematical Sciences (AIMS). - 1930-8345 .- 1930-8337. ; 4:4, s. 599-618
-
Konferensbidrag (refereegranskat)abstract
- Considerations of the backscattering data for the Schrodinger operator H-v = -Delta + v in R-n, where n >= 3 is odd, give rise to an entire analytic mapping from C-0(infinity)(R-n) to C-0(infinity)(R-n), the backscattering transformation. The aim of this paper is to give formulas for B-2(v, w) where B-2 is the symmetric bilinear operator that corresponds to the quadratic part of the backscattering transformation and v and w are rotation invariant.
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| 27. |
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| 28. |
- Berg, Linda, 1961, et al.
(författare)
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Characterisation of Cancer Support and Rehabilitation Programmes: A Swedish Multiple Case Study
- 2014
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Ingår i: The open nursing journal. - : Bentham Science Publishers Ltd.. - 1874-4346. ; 8, s. 1-7
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Tidskriftsartikel (refereegranskat)abstract
- Cancer support and rehabilitation are suggested to be an integral part of cancer care strategies. This study focuses on comparativeness of cancer support and rehabilitation programmes. The aim of this study was to analyse available cancer support and rehabilitation programmes in Sweden presented as complementary to cancer rehabilitation at cancer clinics. A multiple case study design was chosen in order to inquire the small number of existing supportive and rehabilitative cancer programmes. Based on the structures, processes and outcomes of the nine included programmes, three types of cancer support and rehabilitation programmes were identified: multimodal rehabilitation, comprehensive cancer support and art therapy. Cancer support and rehabilitation programmes offer a variety of activities and therapies which are highly valuable and relevant for people with cancer. The typology of cancer support and rehabilitation programmes and comparability between programmes need further inquiry.
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| 29. |
- Bergkvist, Linda, 1979-
(författare)
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A Conceptual Framework for Studying the Successful Outcome of the IS Outsourcing Process from a Relationship Perspective
- 2008
-
Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis has its point of departure in the identified knowledge gap, which includes the importance of the information systems (IS) outsourcing relationship for studying the success of IS outsourcing. This research study, therefore, is structured with the belief that the disregard of the client-IS supplier relationship when studying IS outsourcing is paradoxical. Paradoxical since the impact of the relationship on the overall IS outsourcing can make the difference between success, less success and even failure. In contrast to the majority of prior research, which has focused IS outsourcing in its entirety, this research study percieves IS outsourcing as a process. Because prior research shows that the success or failure of IS outsourcing is connected to its implementation, this thesis focuses the post-contract stage of the IS outsourcing. The purpose chosen and addressed is to develop a conceptual framework for describing and explaining the degree of successful outcome of the IS outsourcing process using a relationship perspective. To approach this purpose, a literature review study is conducted. The literature review study includes the integration of three theoretical fields: IS, interorganisational business relationships and IS outsourcing. The knowledge domains of particular interest are 'strategies, approaches and frameworks for the IS life cycle', 'the interaction approach' and 'IS outsourcing success'. The purpose is focused through the identification of key conditions, dimensions and interrelations among dimensions. These identified elements, constituting the core elements of the conceptual framework, are a result of the conducted literature review study. The key conditions are identified according to their influence on the degree of successful outcome of the IS outsourcing process from a relationship perspective. Due to the large amount of key conditions identified, they are categorised into nine dimensions: Atmosphere, Behaviour, Contract, Environment, Interatction, IS, Management, Organisation and Outcome. The identified interrelations among these dimensions are fruitful since they provide insights and a favourable point of departure for studying the degree of successful outcome of IS outsourcing processes. The main contribution of this thesis is the conceptual framework for the IS outsourcing process. The key conditions, dimensions and interrelations constitute the conceptual framework as a result of their potential for describing and explaining the degree of successful outcome of the IS outsourcing process from a relationship perspective. The application of the conceptual framework provides managers with core elements to be considered during IS outsourcing decision-making and subsequent design of IS outsourcing. Its usage, moreover, is believed to support managers during the operationalisation of the post-contract stage of IS outsourcing processes. Finally, the conceptual framework is a fruitful 'tool' for future empirical research. Fruitful in the sense that it can provide useful and important insights into how different key conditions infuence the degree of successful outcome of IS outsourcing processes and how these key conditions are interrelated.
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| 30. |
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| 31. |
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| 32. |
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| 33. |
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| 34. |
- Chatziioannou, Aristotelis, et al.
(författare)
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Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases
- 2017
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 7
-
Tidskriftsartikel (refereegranskat)abstract
- We recently reported that differential gene expression and DNA methylation profiles in blood leukocytes of apparently healthy smokers predicts with remarkable efficiency diseases and conditions known to be causally associated with smoking, suggesting that blood-based omic profiling of human populations may be useful for linking environmental exposures to potential health effects. Here we report on the sex-specific effects of tobacco smoking on transcriptomic and epigenetic features derived from genome-wide profiling in white blood cells, identifying 26 expression probes and 92 CpG sites, almost all of which are affected only in female smokers. Strikingly, these features relate to numerous genes with a key role in the pathogenesis of cardiovascular disease, especially thrombin signaling, including the thrombin receptors on platelets F2R (coagulation factor II (thrombin) receptor; PAR1) and GP5 (glycoprotein 5), as well as HMOX1 (haem oxygenase 1) and BCL2L1 (BCL2-like 1) which are involved in protection against oxidative stress and apoptosis, respectively. These results are in concordance with epidemiological evidence of higher female susceptibility to tobacco-induced cardiovascular disease and underline the potential of blood-based omic profiling in hazard and risk assessment.
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| 35. |
- Dobbins, Sara E., et al.
(författare)
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Common variation at 10p12.31 near MLLT10 influences meningioma risk
- 2011
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Ingår i: Nature Genetics. - London : Nature America, Inc.. - 1061-4036 .- 1546-1718. ; 43:9, s. 825-827
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Tidskriftsartikel (refereegranskat)abstract
- To identify susceptibility loci for meningioma, we conducted a genome-wide association study of 859 affected individuals (cases) and 704 controls with validation in two independent sample sets totaling 774 cases and 1,764 controls. We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 x 10(-14)). This finding advances our understanding of the genetic basis of meningioma development.
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| 36. |
- Dunér, David, et al.
(författare)
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Society, Worldview and Outreach
- 2018
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Ingår i: Astrobiology and Society in Europe Today. - Cham : Springer International Publishing. - 9783319962641 - 9783319962658 ; , s. 19-24
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Bokkapitel (refereegranskat)
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| 37. |
- Ericson, Thomas, et al.
(författare)
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The Role of the Strategist
- 2001
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Ingår i: Rethinking Strategy. - London : Sage. - 0761956441
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 38. |
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| 39. |
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| 40. |
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| 41. |
- Etezadi, Ehsan, 1993, et al.
(författare)
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Deep reinforcement learning for proactive spectrum defragmentation in elastic optical networks [Invited]
- 2023
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Ingår i: Journal of Optical Communications and Networking. - 1943-0620 .- 1943-0639. ; 15:10, s. E86-E96
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Tidskriftsartikel (refereegranskat)abstract
- The immense growth of Internet traffic calls for advanced techniques to enable the dynamic operation of optical networks, efficient use of spectral resources, and automation. In this paper, we investigate the proactive spectrum defragmentation (SD ) problem in elastic optical networks and propose a novel deep reinforcement learning-based framework DeepDefrag to increase spectral usage efficiency. Unlike the conventional, often threshold-based heuristic algorithms that address a subset of the defragmentation related tasks and have limited automation capabilities, DeepDefrag jointly addresses the three main aspects of the SD process: determining when to perform defragmentation, which connections to reconfigure, and which part of the spectrum to reallocate them to. By considering services attributes, spectrum occupancy state expressed by several different fragmentation metrics, as well as reconfiguration cost, DeepDefragmis able to consistently select appropriate reconfiguration actions over the network lifetime and adapt to changing conditions. Extensive simulation results reveal superior performance of the proposed scheme over a scenario with exhaustive defragmentation and a well-known benchmark heuristic from the literature, achieving lower blocking probability at a smaller defragmentation overhead.
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| 42. |
- Etezadi, Ehsan, 1993, et al.
(författare)
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DeepDefrag: A deep reinforcement learning framework for spectrum defragmentation
- 2022
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Ingår i: 2022 IEEE Global Communications Conference, GLOBECOM 2022 - Proceedings. ; , s. 3694-3699
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Konferensbidrag (refereegranskat)abstract
- Exponential growth of bandwidth demand, spurred by emerging network services with diverse characteristics and stringent performance requirements, drives the need for dynamic operation of optical networks, efficient use of spectral resources, and automation. One of the main challenges of dynamic, resource-efficient Elastic Optical Networks (EONs) is spectrum fragmentation. Fragmented, stranded spectrum slots lead to poor resource utilization and increase the blocking probability of incoming service requests. Conventional approaches for Spectrum Defragmentation (SD) apply various criteria to decide when, and which portion of the spectrum to defragment. However, these polices often address only a subset of tasks related to defragmentation, are not adaptable, and have limited automation potential. To address these issues, we propose DeepDefrag, a novel framework based on reinforcement learning that addresses the main aspects of the SD process: determining when to perform defragmentation, which connections to reconfigure, and which part of the spectrum to reallocate them to. DeepDefrag outperforms the well-known Older-First First-Fit (OF-FF) defragmentation heuristic, achieving lower blocking probability under smaller defragmentation overhead.
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| 43. |
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| 44. |
- Etezadi, Ehsan, 1993, et al.
(författare)
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Proactive Spectrum Defragmentation Leveraging Spectrum Occupancy State Information
- 2023
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Ingår i: International Conference on Transparent Optical Networks. - 2162-7339. ; 2023-July
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Konferensbidrag (refereegranskat)abstract
- One of the main obstacles to efficient resource usage under dynamic traffic in elastic optical networks (EONs) is spectrum fragmentation (SF), leading to blocking of incoming service requests. Proactive spectrum defragmentation (SD) approaches periodically reallocate services to ensure better alignment of available spectrum slots across different links and alleviate blocking. The services for reallocation are commonly selected based on their properties, e.g., age, without detailed consideration of prior or posterior spectrum occupancy states. In this paper, we propose a heuristic algorithm for proactive SD that considers different spectrum fragmentation metrics to select services for reallocation. We analyze the relationship between these metrics and the resulting service blocking probability. Simulation results show that the proposed heuristic outperforms the benchmarking proactive SD algorithms from the literature in reducing blocking probability.
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| 45. |
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| 46. |
- Franks, P. W., et al.
(författare)
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Technological readiness and implementation of genomic-driven precision medicine for complex diseases
- 2021
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Ingår i: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 290:3, s. 602-620
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Forskningsöversikt (refereegranskat)abstract
- The fields of human genetics and genomics have generated considerable knowledge about the mechanistic basis of many diseases. Genomic approaches to diagnosis, prognostication, prevention and treatment - genomic-driven precision medicine (GDPM) - may help optimize medical practice. Here, we provide a comprehensive review of GDPM of complex diseases across major medical specialties. We focus on technological readiness: how rapidly a test can be implemented into health care. Although these areas of medicine are diverse, key similarities exist across almost all areas. Many medical areas have, within their standards of care, at least one GDPM test for a genetic variant of strong effect that aids the identification/diagnosis of a more homogeneous subset within a larger disease group or identifies a subset with different therapeutic requirements. However, for almost all complex diseases, the majority of patients do not carry established single-gene mutations with large effects. Thus, research is underway that seeks to determine the polygenic basis of many complex diseases. Nevertheless, most complex diseases are caused by the interplay of genetic, behavioural and environmental risk factors, which will likely necessitate models for prediction and diagnosis that incorporate genetic and non-genetic data.
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| 47. |
- Färdig, Rickard, et al.
(författare)
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A randomized controlled trial of the illness management and recovery program for persons with schizophrenia.
- 2011
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Ingår i: Psychiatric Services. - : American Psychiatric Association Publishing. - 1075-2730 .- 1557-9700. ; 62:6, s. 606-12
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: The aim of the study was to evaluate the effects of the illness management and recovery (IMR) program on symptoms and psychosocial functioning of individuals with schizophrenia or schizoaffective disorder in an outpatient setting in Sweden.METHODS: A total of 41 persons with schizophrenia or schizoaffective disorder who were receiving treatment at six psychiatric outpatient rehabilitation centers were randomly assigned to either an IMR group for nine months or to treatment as usual (control condition). Assessments were conducted at baseline, posttreatment (nine months), and follow-up (21 months) and included self-reports and ratings by clinicians (both blind and nonblind to treatment assignment) of illness management, psychiatric symptoms, recovery, coping, quality of life, hospitalization, insight, and suicidal ideation.RESULTS: As measured by self-report and ratings of nonblinded clinicians, IMR program participants demonstrated significantly greater improvement in illness management than participants in the control condition. Ratings of psychiatric symptoms by blinded clinicians using the Psychosis Evaluation Tool for Common Use by Caregivers and self-reported ratings of psychosocial functioning on the Ways of Coping Questionnaire also showed better outcomes than for participants in treatment as usual. A statistically significant decrease in suicidal ideation between baseline and follow-up was found for IMR program participants.CONCLUSIONS: The study supports previous findings and suggests that the IMR program is effective in improving the ability of individuals with schizophrenia to better manage their illness.
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| 48. |
- Färdig, Rickard, et al.
(författare)
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A Randomized Controlled Trial of the Illness Management and Recovery Program for Persons With Schizophrenia
- 2011
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Ingår i: Psychiatric Services. - 1075-2730 .- 1557-9700. ; 62:6, s. 606-612
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of the study was to evaluate the effects of the illness management and recovery (IMR) program on symptoms and psychosocial functioning of individuals with schizophrenia or schizoaffective disorder in an outpatient setting in Sweden. Methods: A total of 41 persons with schizophrenia or schizoaffective disorder who were receiving treatment at six psychiatric outpatient rehabilitation centers were randomly assigned to either an IMR group for nine months or to treatment as usual (control condition). Assessments were conducted at baseline, posttreatment (nine months), and follow-up (21 months) and included self-reports and ratings by clinicians (both blind and nonblind to treatment assignment) of illness management, psychiatric symptoms, recovery, coping, quality of life, hospitalization, insight, and suicidal ideation. Results: As measured by self-report and ratings of nonblinded clinicians, IMR program participants demonstrated significantly greater improvement in illness management than participants in the control condition. Ratings of psychiatric symptoms by blinded clinicians using the Psychosis Evaluation Tool for Common Use by Caregivers and self-reported ratings of psychosocial functioning on the Ways of Coping Questionnaire also showed better outcomes than for participants in treatment as usual. A statistically significant decrease in suicidal ideation between baseline and follow-up was found for IMR program participants. Conclusions: The study supports previous findings and suggests that the IMR program is effective in improving the ability of individuals with schizophrenia to better manage their illness.
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| 49. |
- Färdig, Rickard, et al.
(författare)
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Evaluation of the Illness Management and Recovery Scale in schizophrenia and schizoaffective disorder
- 2011
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Ingår i: Schizophrenia Research. - : Elsevier BV. - 0920-9964 .- 1573-2509. ; 132:2-3, s. 157-164
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Tidskriftsartikel (refereegranskat)abstract
- The aim of the present study was to evaluate the psychometric properties of the parallel client and clinician versions of the Illness Management and Recovery Scale (IMRS) developed to monitor the clients' progress in the Illness Management and Recovery (IMR) program in schizophrenia. A total of 107 study participants completed assessments of the IMRS, interview-based ratings of psychiatric symptoms, self-ratings of psychiatric symptoms, perception of recovery, and quality of life. Case managers completed the clinician version of the IMRS. Both versions of the scale demonstrated satisfactory internal reliability and strong test-retest reliability. The results also indicated convergent validity with interview-based ratings of psychiatric symptoms, self-rated symptoms, perception of recovery, and quality of life for both versions of the IMRS. These findings support the utility of the IMRS as a measure of illness self-management and recovery in clients with schizophrenia.
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| 50. |
- Färdig, Rickard, 1975-
(författare)
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Illness Management and Recovery : Implementation and evaluation of a psychosocial program for schizophrenia and schizoaffective disorder
- 2012
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The aim of the present thesis was to examine the effectiveness of the Illness Management and Recovery (IMR) program for teaching clients with schizophrenia or schizoaffective disorder to better manage their illness and to promote recovery. This was accomplished through an examination of the program’s effects on psychosocial functioning and psychopathology, the evaluation of general and specific impact of neurocognition on learning the fundamentals of illness self-management, and the impact of symptom severity on outcome of the IMR program. The utility of the illness management and recovery scale to evaluate illness self-management of clients with schizophrenia and schizoaffective disorder was also investigated.The effects of the IMR program were evaluated in a randomized controlled trial that compared participants in the program to participants receiving treatment as usual. 41 participants were recruited at six psychiatric outpatient rehabilitation centers in Uppsala, Sweden, and were randomly assigned to IMR groups for approximately 40 sessions or to a treatment as usual control condition. The IMR program participants demonstrated greater improvement compared to participants in treatment as usual in illness self-management, reduced psychiatric symptoms, improved coping skills, and decreases in suicidal ideation. The findings suggest that the IMR program is effective in improving the ability of individuals with schizophrenia and schizoaffective disorder to better manage their illness.Possible association between neurocognitive functioning and the acquisition of illness self-management skills was investigated in a total of 53 participants who completed the IMR program. Speed of processing was related to client reported illness self-management skills acquisition, before and after controlling for psychiatric symptoms and medication, but neurocognitive functioning did not predict improvement in clinician ratings of client illness self-management skills. The findings suggest that compromised neurocognitive functioning does not reduce response to training in illness self-management.The impact of symptom severity on outcome of the IMR program was explored in 52 participants who completed the program. The results suggest that significantly more participants met the severity criterion of remission at post-treatment, and it appears that participants not reaching the severity criterion at post-treatment, also benefited from the IMR program, as indicated by the similar effect sizes of the two subgroups (meeting versus not meeting the severity criterion at post-treatment).The psychometric properties of the Illness Management and Recovery Scale (IMRS) were evaluated in 107 participants with a diagnosis of schizophrenia or schizoaffective disorder. And an item-by-item investigation was conducted in order to establish their utility in monitoring the clients' progress in the IMR program. Both the client and clinician version of the IMRS demonstrated satisfactory internal consistency, large test-retest reliability, and convergent validity with conceptually related measures of psychiatric symptoms, quality of life, and perception of recovery. The findings support the utility of the IMRS as a measure of illness self-management and recovery in clients with schizophrenia and schizoaffective disorder.The general findings of this thesis support the IMR program to be effective in improving the ability of the participants to manage their disorder. The impact of neurocognitive dysfunction on the participants’ ability to learn the fundamentals of illness self-management seems to be limited, and symptom severity did not limit the benefits of the IMR program. Support for the utility of the IMRS to monitor the participants’ progress in the program was also found, providing a brief and economical method for assessing outcome of the IMR program.
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