| 1. |
- De Marco, O., et al.
(author)
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The messy death of a multiple star system and the resulting planetary nebula as observed by JWST
- 2022
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In: Nature Astronomy. - : Springer Science and Business Media LLC. - 2397-3366. ; 6:12, s. 1421-1432
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Journal article (peer-reviewed)abstract
- Planetary nebulae—the ejected envelopes of red giant stars—provide us with a history of the last, mass-losing phases of 90% of stars initially more massive than the Sun. Here we analyse images of the planetary nebula NGC 3132 from the James Webb Space Telescope (JWST) Early Release Observations. A structured, extended hydrogen halo surrounding an ionized central bubble is imprinted with spiral structures, probably shaped by a low-mass companion orbiting the central star at about 40–60 au. The images also reveal a mid-infrared excess at the central star, interpreted as a dusty disk, which is indicative of an interaction with another closer companion. Including the previously known A-type visual companion, the progenitor of the NGC 3132 planetary nebula must have been at least a stellar quartet. The JWST images allow us to generate a model of the illumination, ionization and hydrodynamics of the molecular halo, demonstrating the power of JWST to investigate complex stellar outflows. Furthermore, new measurements of the A-type visual companion allow us to derive the value for the mass of the progenitor of a central star with excellent precision: 2.86 ± 0.06 M⊙. These results serve as pathfinders for future JWST observations of planetary nebulae, providing unique insight into fundamental astrophysical processes including colliding winds and binary star interactions, with implications for supernovae and gravitational-wave systems.
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| 2. |
- Fissolo, N., et al.
(author)
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Serum biomarker levels predict disability progression in patients with primary progressive multiple sclerosis
- 2024
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In: Journal of Neurology Neurosurgery and Psychiatry. - 0022-3050. ; 95:5, s. 410-418
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Journal article (peer-reviewed)abstract
- BackgroundWe aimed to investigate the potential of serum biomarker levels to predict disability progression in a multicentric real-world cohort of patients with primary progressive multiple sclerosis (PPMS).MethodsA total of 141 patients with PPMS from 18 European MS centres were included. Disability progression was investigated using change in Expanded Disability Status Scale (EDSS) score over three time intervals: baseline to 2 years, 6 years and to the last follow-up. Serum levels of neurofilament light chain (sNfL), glial fibrillar acidic protein (sGFAP) and chitinase 3-like 1 (sCHI3L1) were measured using single-molecule array assays at baseline. Correlations between biomarker levels, and between biomarkers and age were quantified using Spearman's r. Univariable and multivariable linear models were performed to assess associations between biomarker levels and EDSS change over the different time periods.ResultsMedian (IQR) age of patients was 52.9 (46.4-58.5) years, and 58 (41.1%) were men. Median follow-up time was 9.1 (7.0-12.6) years. Only 8 (5.7%) patients received treatment during follow-up. sNfL and sGFAP levels were moderately correlated (r=0.43) and both weakly correlated with sCHI3L1 levels (r=0.19 and r=0.17, respectively). In multivariable analyses, levels of the three biomarkers were associated with EDSS changes across all time periods. However, when analysis was restricted to non-inflammatory patients according to clinical and radiological parameters (n=64), only sCHI3L1 levels remained associated with future EDSS change.ConclusionsLevels of sNfL, sGFAP and sCHI3L1 are prognostic biomarkers associated with disability progression in patients with PPMS, being CHI3L1 findings less dependent on the inflammatory component associated with disease progression.
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| 3. |
- Herenz, E. C., et al.
(author)
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A ∼15 kpc outflow cone piercing through the halo of the blue compact metal-poor galaxy SBS 0335–052E
- 2023
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In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 670
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Journal article (peer-reviewed)abstract
- Context. Outflows from low-mass star-forming galaxies are a fundamental ingredient for models of galaxy evolution and cosmology. Despite seemingly favourable conditions for outflow formation in compact starbursting galaxies, convincing observational evidence for kiloparsec-scale outflows in such systems is scarce.Aims. The onset of kiloparsec-scale ionised filaments in the halo of the metal-poor compact dwarf SBS 0335−052E was previously not linked to an outflow. In this paper we investigate whether these filaments provide evidence for an outflow.Methods. We obtained new VLT/MUSE WFM and deep NRAO/VLA B-configuration 21 cm data of the galaxy. The MUSE data provide morphology, kinematics, and emission line ratios of Hβ/Hα and [O III]λ5007/Hα of the low surface-brightness filaments, while the VLA data deliver morphology and kinematics of the neutral gas in and around the system. Both datasets are used in concert for comparisons between the ionised and the neutral phase.Results. We report the prolongation of a lacy filamentary ionised structure up to a projected distance of 16 kpc at SBHα = 1.5 × 10−18 erg s cm−2 arcsec−2. The filaments exhibit unusual low Hα/Hβ ≈ 2.4 and low [O III]/Hα ∼ 0.4 − 0.6 typical of diffuse ionised gas. They are spectrally narrow (∼20 km s−1) and exhibit no velocity sub-structure. The filaments extend outwards from the elongated H I halo. On small scales, the NHI peak is offset from the main star-forming sites. The morphology and kinematics of H I and H II reveal how star-formation-driven feedback interacts differently with the ionised and the neutral phase.Conclusions. We reason that the filaments are a large-scale manifestation of star-formation- driven feedback, namely limb-brightened edges of a giant outflow cone that protrudes through the halo of this gas-rich system. A simple toy model of such a conical structure is found to be commensurable with the observations.
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