SwePub - sökning: WFRF:(Nguyen Van Thanh)

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1.	Tran, Ngoc Hieu, et al. (författare) Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data 2020 Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 10:1 Tidskriftsartikel (refereegranskat)abstract The under-representation of several ethnic groups in existing genetic databases and studies have undermined our understanding of the genetic variations and associated traits or diseases in many populations. Cost and technology limitations remain the challenges in performing large-scale genome sequencing projects in many developing countries, including Vietnam. As one of the most rapidly adopted genetic tests, non-invasive prenatal testing (NIPT) data offers an alternative untapped resource for genetic studies. Here we performed a large-scale genomic analysis of 2683 pregnant Vietnamese women using their NIPT data and identified a comprehensive set of 8,054,515 single-nucleotide polymorphisms, among which 8.2% were new to the Vietnamese population. Our study also revealed 24,487 disease-associated genetic variants and their allele frequency distribution, especially 5 pathogenic variants for prevalent genetic disorders in Vietnam. We also observed major discrepancies in the allele frequency distribution of disease-associated genetic variants between the Vietnamese and other populations, thus highlighting a need for genome-wide association studies dedicated to the Vietnamese population. The resulted database of Vietnamese genetic variants, their allele frequency distribution, and their associated diseases presents a valuable resource for future genetic studies.
2.	Duy, Nguyen Van, et al. (författare) Design and fabrication of effective gradient temperature sensor array based on bilayer SnO2/Pt for gas classification 2022 Ingår i: Sensors and actuators. B, Chemical. - : Elsevier. - 0925-4005 .- 1873-3077. ; 351 Tidskriftsartikel (refereegranskat)abstract Classification of different gases is important, and it is possible to use different gas sensors for this purpose. Electronic noses, for example, combine separated gas sensors into an array for detecting different gases. However, the use of separated sensors in an array suffers from being bulky, high-energy consumption and complex fabrication processes. Generally, gas sensing properties, including gas selectivity, of semiconductor gas sensors are strongly dependent on their working temperature. It is therefore feasible to use a single device composed of identical sensors arranged in a temperature gradient for classification of multiple gases. Herein, we introduce a design for simple fabrication of gas sensor array based on bilayer Pt/SnO2 for real-time monitoring and classification of multiple gases. The study includes design simulation of the sensor array to find an effective gradient temperature, fabrication of the sensors and test of their performance. The array, composed of five sensors, was fabricated on a glass substrate without the need of backside etching to reduce heat loss. A SnO2 thin film sensitized with Pt on top deposited by sputtering was used as sensing material. The sensor array was tested against different gases including ethanol, methanol, isopropanol, acetone, ammonia, and hydrogen. Radar plots and principal component analysis were used to visualize the distinction of the tested gases and to enable effective classification.
3.	Kreibich, Heidi, et al. (författare) Panta Rhei benchmark dataset : Socio-hydrological data of paired events of floods and droughts 2023 Ingår i: Earth System Science Data. - : Copernicus Publications. - 1866-3508 .- 1866-3516. ; 15:5, s. 2009-2023 Tidskriftsartikel (refereegranskat)abstract As the adverse impacts of hydrological extremes increase in many regions of the world, a better understanding of the drivers of changes in risk and impacts is essential for effective flood and drought risk management and climate adaptation. However, there is currently a lack of comprehensive, empirical data about the processes, interactions, and feedbacks in complex human-water systems leading to flood and drought impacts. Here we present a benchmark dataset containing socio-hydrological data of paired events, i.e. two floods or two droughts that occurred in the same area. The 45 paired events occurred in 42 different study areas and cover a wide range of socio-economic and hydro-climatic conditions. The dataset is unique in covering both floods and droughts, in the number of cases assessed and in the quantity of socio-hydrological data. The benchmark dataset comprises (1) detailed review-style reports about the events and key processes between the two events of a pair; (2) the key data table containing variables that assess the indicators which characterize management shortcomings, hazard, exposure, vulnerability, and impacts of all events; and (3) a table of the indicators of change that indicate the differences between the first and second event of a pair. The advantages of the dataset are that it enables comparative analyses across all the paired events based on the indicators of change and allows for detailed context- and location-specific assessments based on the extensive data and reports of the individual study areas. The dataset can be used by the scientific community for exploratory data analyses, e.g. focused on causal links between risk management; changes in hazard, exposure and vulnerability; and flood or drought impacts. The data can also be used for the development, calibration, and validation of socio-hydrological models. The dataset is available to the public through the GFZ Data Services (Kreibich et al., 2023, 10.5880/GFZ.4.4.2023.001).
4.	Kreibich, Heidi, et al. (författare) The challenge of unprecedented floods and droughts in risk management 2022 Ingår i: Nature. - : Springer Nature. - 0028-0836 .- 1476-4687. ; 608:7921, s. 80-86 Tidskriftsartikel (refereegranskat)abstract Risk management has reduced vulnerability to floods and droughts globally, yet their impacts are still increasing. An improved understanding of the causes of changing impacts is therefore needed, but has been hampered by a lack of empirical data4,5. On the basis of a global dataset of 45 pairs of events that occurred within the same area, we show that risk management generally reduces the impacts of floods and droughts but faces difficulties in reducing the impacts of unprecedented events of a magnitude not previously experienced. If the second event was much more hazardous than the first, its impact was almost always higher. This is because management was not designed to deal with such extreme events: for example, they exceeded the design levels of levees and reservoirs. In two success stories, the impact of the second, more hazardous, event was lower, as a result of improved risk management governance and high investment in integrated management. The observed difficulty of managing unprecedented events is alarming, given that more extreme hydrological events are projected owing to climate change.
5.	Son, Dang Ngoc, et al. (författare) A novel design and fabrication of self-heated In2O3 nanowire gas sensor on for ethanol detection 2022 Ingår i: Sensors and Actuators A-Physical. - : Elsevier. - 0924-4247 .- 1873-3069. ; 345 Tidskriftsartikel (refereegranskat)abstract Many attempts have been made on the design and fabrication of low-power consumption gas sensor for application on the Internet of Things and portable devices. The performance of gas sensors includes sensitivity, selectivity, and power consumption, which are strongly dependent on the configuration of the device such as the gap size between two electrodes, the sensing material, and operation principle. Here, self-heated In2O3 nanowire-based gas sensors were designed and fabricated by on-chip growth technique via thermal evaporation to work at room temperature. The effect of electrode gap (10-40 mu m) on the power consumption and gas sensing performance of the In2O3 nanowire sensors was studied. With the large gap of 40 mu m, the sensor exhibited excellent sensing characteristics of low power consumption (1.06 mW) with ability to detect ethanol gas down to 20 ppm effectively. We also examined the role of nanowire conductivity in the performance of the self-heated sensor in the detection of reducing gas. The sensor demonstrated rapid response and recovery times of less than a minute, exceptional stability, and remarkable recovery.
6.	Thanh Hoan, Nguyen, et al. (författare) Novel Time Series Bagging Based Hybrid Models for Predicting Historical Water Levels in the Mekong Delta Region, Vietnam 2022 Ingår i: CMES - Computer Modeling in Engineering & Sciences. - : Tech Science Press. - 1526-1492 .- 1526-1506. ; 131:3, s. 1431-1449 Tidskriftsartikel (refereegranskat)abstract Water level predictions in the river, lake and delta play an important role in flood management. Every year Mekong River delta of Vietnam is experiencing flood due to heavy monsoon rains and high tides. Land subsidence may also aggravate flooding problems in this area. Therefore, accurate predictions of water levels in this region are very important to forewarn the people and authorities for taking timely adequate remedial measures to prevent losses of life and property. There are so many methods available to predict the water levels based on historical data but nowadays Machine Learning (ML) methods are considered the best tool for accurate prediction. In this study, we have used surface water level data of 18 water level measurement stations of the Mekong River delta from 2000 to 2018 to build novel time-series Bagging based hybrid ML models namely: Bagging (RF), Bagging (SOM) and Bagging (M5P) to predict historical water levels in the study area. Performances of the Bagging-based hybrid models were compared with Reduced Error Pruning Trees (REPT), which is a benchmark ML model. The data of 19 years period was divided into 70:30 ratio for the modeling. The data of the period 1/2000 to 5/2013 (which is about 70% of total data) was used for the training and for the period 5/2013 to 12/2018 (which is about 30% of total data) was used for testing (validating) the models. Performance of the models was evaluated using standard statistical measures: Coefficient of Determination (R2), Root Mean Square Error (RMSE) and Mean Absolute Error (MAE). Results show that the performance of all the developed models is good (R2 > 0.9) for the prediction of water levels in the study area. However, the Bagging-based hybrid models are slightly better than another model such as REPT. Thus, these Bagging-based hybrid time series models can be used for predicting water levels at Mekong data.
7.	Duoc, Vo Thanh, et al. (författare) Room temperature highly toxic NO2 gas sensors based on rootstock/scion nanowires of SnO2/ZnO, ZnO/SnO2, SnO2/SnO2 and, ZnO/ZnO 2021 Ingår i: Sensors and actuators. B, Chemical. - : Elsevier. - 0925-4005 .- 1873-3077. ; 348 Tidskriftsartikel (refereegranskat)abstract Grafted structures between SnO2 and ZnO nanowires were realized in a two-step process of growth. First, the rootstocks of SnO2 or ZnO nanowires were synthesized by thermal evaporation technique. Second, a thin Au layer was sputter deposited on the sample and synthesis of nanowire scions of ZnO or SnO2, respectively, on the rootstocks was realized by thermal evaporation technique again. In both growth steps, SnO2 powder or a mixture of ZnO and carbon powders was use as source materials for the synthesis. Different rootstock/scion combinations of SnO2/ZnO, ZnO/SnO2 nanowires (called heterostructures) and ZnO/ZnO, SnO2/SnO2 nanowires (called homostructures) were synthesised. The fabricated grafted nanowires were examined by field-emission scanning electron microscope and their compositions were analyzed by energy dispersive spectroscopy and X-ray diffraction analysis. The test results indicate that this type of nanostructure material is very promising for NO2 gas sensing at ppt level at room temperature. Among the fabricated structures the SnO2/ZnO nanowires showed the best sensing performance with the high sensitivity and fast response and recovery time. We also discussed the gas sensing mechanism of the fabricated sensors based on the band diagram.
8.	Kim, Min Seo, et al. (författare) Global burden of peripheral artery disease and its risk factors, 1990-2019 : a systematic analysis for the Global Burden of Disease Study 2019 2023 Ingår i: The Lancet Global Health. - : Elsevier. - 2214-109X. ; 11:10, s. E1553-E1565 Tidskriftsartikel (refereegranskat)abstract Background: Peripheral artery disease is a growing public health problem. We aimed to estimate the global disease burden of peripheral artery disease, its risk factors, and temporospatial trends to inform policy and public measures.Methods: Data on peripheral artery disease were modelled using the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2019 database. Prevalence, disability-adjusted life years (DALYs), and mortality estimates of peripheral artery disease were extracted from GBD 2019. Total DALYs and age-standardised DALY rate of peripheral artery disease attributed to modifiable risk factors were also assessed.Findings: In 2019, the number of people aged 40 years and older with peripheral artery disease was 113 million (95% uncertainty interval [UI] 99 center dot 2-128 center dot 4), with a global prevalence of 1 center dot 52% (95% UI 1 center dot 33-1 center dot 72), of which 42 center dot 6% was in countries with low to middle Socio-demographic Index (SDI). The global prevalence of peripheral artery disease was higher in older people, (14 center dot 91% [12 center dot 41-17 center dot 87] in those aged 80-84 years), and was generally higher in females than in males. Globally, the total number of DALYs attributable to modifiable risk factors in 2019 accounted for 69 center dot 4% (64 center dot 2-74 center dot 3) of total peripheral artery disease DALYs. The prevalence of peripheral artery disease was highest in countries with high SDI and lowest in countries with low SDI, whereas DALY and mortality rates showed U-shaped curves, with the highest burden in the high and low SDI quintiles.Interpretation: The total number of people with peripheral artery disease has increased globally from 1990 to 2019. Despite the lower prevalence of peripheral artery disease in males and low-income countries, these groups showed similar DALY rates to females and higher-income countries, highlighting disproportionate burden in these groups. Modifiable risk factors were responsible for around 70% of the global peripheral artery disease burden. Public measures could mitigate the burden of peripheral artery disease by modifying risk factors.
9.	Chu Manh, Hung, et al. (författare) ZnO coral-like nanoplates decorated with Pd nanoparticles for enhanced VOC gas sensing 2021 Ingår i: Journal of Science: Advanced Materials and Devices. - Hanoi, Vietnam : Elsevier. - 2468-2284 .- 2468-2179. ; 6:3, s. 453-461 Tidskriftsartikel (refereegranskat)abstract A high working temperature of the ZnO nanomaterial-based gas sensor could shorten the lifetime of the sensor and increase its power consumption. Enhancing the volatile organic compound (VOC) sensing performance of ZnO nanomaterial-based gas sensors in terms of gas response and temperature is vital for their practical application. Decoration of noble metals onto nanostructures is an effective approach for improving their sensing characteristics. Herein, hydrothermally synthesized ZnO coral-like nanoplates decorated with Pd nanoparticles are introduced to achieve the improved VOC sensing performance. The morphology, crystal structure, composition, atomic structure, and gas sensing properties of the synthesized pristine and Pd–ZnO coral-like nanoplates were investigated. The results showed a remarkable reduction of optimal working temperature from 450 °C for the pristine ZnO based sensor to 350 °C for the Pd–ZnO based sensor. The sensor response to acetone at the optimal operating temperature of 350 °C was improved three times by surface decoration with Pd nanoparticles. The response time and recovery time of the Pd–ZnO sensor were about three times faster than that of the pristine ZnO sensor. The Pd–ZnO sensor reached a theoretical detection limit of 17 ppt and a sensitivity of 3.5–2.5 ppm acetone at 350 °C. The sensor transient stability after several on/off switching cycles from air to gas revealed the effective reusability of the fabricated devices. A plausible mechanism for the VOC sensing of the porous Pd–ZnO coral-like nanoplate-based sensor is also discussed.
10.	Lam, Steven, et al. (författare) Unpacking the Theory Behind One Health Food Safety Programs : A Vietnam Case Study 2021 Ingår i: Frontiers in Veterinary Science. - : Frontiers Media S.A.. - 2297-1769. ; 8 Tidskriftsartikel (refereegranskat)abstract Many One Health programs are inherently complex, characterized by multiple perspectives from multiple sectors, delivery across various scales, and a focus on complex problems at the convergence of people, animals, and the environment. This complexity makes them difficult to conceptualize, requiring frameworks to organize the different program components. Evaluation frameworks that unpack the sequence of events linking program activities to outcomes (e.g., Theory of Change) and track outcomes (e.g., Outcome Mapping) show promise in supporting the development of One Health programs. While widely used in international development and health contexts, there has been little reflection on the use of Theory of Change and Outcome Mapping within One Health efforts. This paper reflects on the process of applying these frameworks to conceptualize a One Health food safety program in Vietnam. We find Theory of Change fostered the characterization of a change pathway toward safer pork, while Outcome Mapping kept us informed of where along the change pathway we were. One Health programs considering evaluation frameworks should adopt elements that make sense to them, be intentional about co-designing the evaluation, and view evaluation as a process, not a product.
11.	Nguyen, Thanh N, et al. (författare) Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up. 2023 Ingår i: Neurology. - 1526-632X. ; 100:4 Tidskriftsartikel (refereegranskat)abstract Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020).We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases.There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1-6.9]; p < 0.0001). ICH volumes declined from 29,585 to 28,156 (4.8% [5.1-4.6]; p < 0.0001) and IVT volume from 24,584 to 23,077 (6.1% [6.4-5.8]; p < 0.0001). Larger declines were observed at high-volume compared with low-volume centers (all p < 0.0001). There was no significant change in mechanical thrombectomy volumes (0.7% [0.6-0.9]; p = 0.49). Stroke was diagnosed in 1.3% [1.31-1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82-2.97], 5,656/195,539) of all stroke hospitalizations.There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year.This study is registered under NCT04934020.
12.	Van Duy, Lai, et al. (författare) Room Temperature Ammonia Gas Sensor Based on p-Type-like V2O5 Nanosheets towards Food Spoilage Monitoring 2023 Ingår i: Nanomaterials. - : MDPI. - 2079-4991. ; 13:1, s. 146-146 Tidskriftsartikel (refereegranskat)abstract Gas sensors play an important role in many areas of human life, including the monitoring of production processes, occupational safety, food quality assessment, and air pollution monitoring. Therefore, the need for gas sensors to monitor hazardous gases, such as ammonia, at low operating temperatures has become increasingly important in many fields. Sensitivity, selectivity, low cost, and ease of production are crucial characteristics for creating a capillary network of sensors for the protection of the environment and human health. However, developing gas sensors that are not only efficient but also small and inexpensive and therefore integrable into everyday life is a difficult challenge. In this paper, we report on a resistive sensor for ammonia detection based on thin V2O5 nanosheets operating at room temperature. The small thickness and porosity of the V2O5 nanosheets give the sensors good performance for sensing ammonia at room temperature (RT), with a relative change of resistance of 9.4% to 5 ppm ammonia (NH3) and an estimated detection limit of 0.4 ppm. The sensor is selective with respect to the seven interferents tested; it is repeatable and stable over the long term (four months). Although V2O5 is generally an n-type semiconductor, in this case the nanosheets show a p-type semiconductor behavior, and thus a possible sensing mechanism is proposed. The device’s performance, along with its size, low cost, and low power consumption, makes it a good candidate for monitoring freshness and spoilage along the food supply chain.Keywords: gas sensor; vanadium pentoxide; ammonia; nanosheet; room temperature; food quality
13.	Duoc, Vo Thanh, et al. (författare) Hydrogen gas sensor based on self-heating effect of SnO2/Pt thin film with ultralow power consumption 2024 Ingår i: International journal of hydrogen energy. - : Elsevier. - 0360-3199 .- 1879-3487. ; 61, s. 774-782 Tidskriftsartikel (refereegranskat)abstract Self-heating of sensing elements on gas sensors is an effective solution to avoid using external heaters. In this paper, a self-heated hydrogen gas sensor is presented. The sensor was created using the DC sputtering method, which involved fabricating it on a thermal-insulating Kapton flexible substrate. This process utilized a thin film of SnO2 with thick 50 nm that was modified with nanoclusters of Pt, serving as the sensing material. The SnO2/Pt material film was analyzed for microstructure and composition by SEM, XRD, and XPS analysis. Infrared images show that the self-heating effect is mainly concentrated in the strip of gas-sensitive material. It showed many good performances, such as high sensitivity (able to detect down to 50 ppm of H2), good selectivity (poor response to CO, NH3, H2S, and NO2), the sensor's performance is little changed by environmental humidity, and low power consumption (89 μW at 5V). The sensor is also stable and low-cost, suitable for portable H2 detection devices due to its low generated heat and small size.
14.	Duy, Nguyen Van, et al. (författare) Enhancement of NH3 gas sensing with Ag-Pt co-catalyst on SnO2 nanofilm towards medical diagnosis 2023 Ingår i: Thin Solid Films. - : Elsevier. - 0040-6090 .- 1879-2731. ; 767 Tidskriftsartikel (refereegranskat)abstract Exhaled breath analysis is a noninvasive diagnostic method for fatal disease monitoring and screening, which is recently gained extensive interest of researchers worldwide emphasizing on the development of effective chemiresistive gas sensor for practical application. Here, the Ag-Pt bimetallic nanoparticles were used to deco-rate nanofilms of SnO2 making different gas sensors with high performance. We found that the bimetal alloy improved the sensor performance significantly with super sensitivity as compared with the separate Ag and Pt catalyst. The right ratio of the bimetal made the sensor very sensitive to NH3, so that it was able to quickly (12 s) detect 1 parts-per-million of NH3 with a response of 4.31 at a temperature of 250 degrees C. The sensor limit of detection for NH3 was less than 10 parts-per-billion. The response of the sensor was negligibly affected by humidity and interfering gases. The results showed that the tiny, robust, and inexpensive sensor developed in this work can be used in breath analysis for early diagnosis via NH3 monitoring.
15.	Quyen, Vu Thi, et al. (författare) Enhanced recovery of phosphate as a value-added product from wastewater by using lanthanum modified carbon-fiber 2021 Ingår i: Chemosphere. - : Elsevier. - 0045-6535 .- 1879-1298. ; 281 Tidskriftsartikel (refereegranskat)abstract The aim of this study is to present the potential of activated carbon fiber (CF) impregnated with lanthanum (La) as a novel adsorbent (La-CF) of phosphate-phosphorus (P) and to assess the value-added due to P-recovery from wastewater using La-CF. The CF were loaded with La and the loaded CF was then calcined at 500 degrees C. The La-CF adsorbent was used in a series of batch experiments to characterize the adsorption of P at pH of 6-10 and P concentrations of 1-200 mg/L. Physical-chemical properties such as surface morphology, surface charge, surface area, and surface chemistry were determined for the La-CF. The La-CF exhibited adsorption capacity of 196.5 mg/g, fast sorption kinetics and high selectivity for P removal from aqueous solution. La-CF removed 97.3% of P from wastewater and achieved P-level to below 2 mg/L. It was repetitively reused over 10 times in successive cycles to remove P from wastewater. The value-added by recovery of P from wastewater was calculated at around 0.12 US$/L, demonstrating economic benefits of La-CF. In conclusion, the successful removal, recycling, and recovery value-added of P using La-CF adsorbent displayed good potential for developing the technology for treatment of wastewaters to recover valuable compounds such as phosphorus.
16.	Berg, Håkan, et al. (författare) An ecological economic comparison between integrated rice-fish farming and rice monocultures with low and high dikes in the Mekong Delta, Vietnam 2023 Ingår i: Ambio. - 0044-7447 .- 1654-7209. ; 52:9, s. 1462-1474 Tidskriftsartikel (refereegranskat)abstract This study makes an ecological economic comparison between three different rice farming strategies in the Mekong Delta. Interviews were made with 30 farmers with two crops of rice and low dikes (2RLd), 30 farmers with three crops of rice and high dikes (3RHd) and 18 farmers with two crops of rice and one crop of fish (2RF). 2RF farmers had the highest annual net income and benefit cost ratio, because of low production costs and high yields of rice and fish. 2RLd farmers had the lowest annual net income. 3RHd had the highest annual rice yield, but also used the highest amount of rice seeds and agrochemicals, generating the lowest benefit cost ratio. Most farmers (70%) preferred two crops because of a higher production efficiency. High dikes and frequent use of pesticides and fertilizers were seen to decrease the water and rice quality, connectivity and biodiversity in farms with three crops. It is concluded that rice farming with two crops, and especially if integrated with fish and applying IPM, provides a sustainable alternative to rice farming with three crops and high dikes, because it makes use of the high connectivity within the rice-field ecosystem for an efficient production of healthy food through increased recycling of nutrients and natural pest control mechanisms.
17.	Nguyen, Nhan Thanh, et al. (författare) Joint Communications and Sensing Design for Multi-Carrier MIMO Systems 2023 Ingår i: IEEE Workshop on Statistical Signal Processing Proceedings. ; 2023-July, s. 110-114 Konferensbidrag (refereegranskat)abstract In conventional joint communications and sensing (JCAS) designs for multi-carrier multiple-input multiple-output (MIMO) systems, the dual-functional waveforms are often optimized for the whole frequency band, resulting in limited communications-sensing performance tradeoff. To overcome the limitation, we propose employing a subset of subcarriers for JCAS, while the communications function is performed over all the subcarriers. This offers more degrees of freedom to enhance the communications performance under a given sensing accuracy. We first formulate the rate maximization under the sensing accuracy constraint to optimize the beamformers and JCAS subcarriers. The problem is solved via Riemannian manifold optimization and closed-form solutions. Numerical results for an 8 × 4 MIMO system with 64 subcarriers show that compared to the conventional subcarrier sharing scheme, the proposed scheme employing 16 JCAS subcarriers offers 60% improvement in the achievable communications rate at the signal-to-noise ratio of 10 dB. Meanwhile, this scheme generates the sensing beampattern with the same quality as the conventional JCAS design.
18.	Scutelnic, Adrian, et al. (författare) Characteristics and outcomes of cerebral venous thrombosis associated with COVID-19 2024 Ingår i: EUROPEAN STROKE JOURNAL. - 2396-9873 .- 2396-9881. Tidskriftsartikel (refereegranskat)abstract Introduction: Previous reports and meta-analyses derived from small case series reported a mortality rate of up to 40% in patients with coronavirus disease 2019 associated cerebral venous thrombosis (COVID-CVT). We assessed the clinical characteristics and outcomes in an international cohort of patients with COVID-CVT. Patients and methods: This was a registry study of consecutive COVID-CVT patients diagnosed between March 2020 and March 2023. Data collected by the International Cerebral Venous Thrombosis Consortium from patients with CVT diagnosed between 2017 and 2018 served as a comparison. Outcome analyses were adjusted for age and sex. Results: We included 70 patients with COVID-CVT from 23 hospitals in 15 countries and 206 controls from 14 hospitals in 13 countries. The proportion of women was smaller in the COVID-CVT group (50% vs 68%, p < 0.01). A higher proportion of COVID-CVT patients presented with altered mental state (44% vs 25%, p < 0.01), the median thrombus load was higher in COVID-CVT patients (3 [IQR 2-4] vs 2 [1-3], p < 0.01) and the length of hospital stay was longer compared to controls (11 days [IQR 7-20] vs 8 [4-15], p = 0.02). In-hospital mortality did not differ (5/67 [7%, 95% CI 3-16] vs 7/206 [3%, 2-7], aOR 2.6 [95% CI 0.7-9]), nor did the frequency of functional independence after 6 months (modified Rankin Scale 0-2; 45/58 [78%, 95% CI 65-86] vs 161/185 [87%, 81-91], aOR 0.5 [95% CI 0.2-1.02]). Conclusion: In contrast to previous studies, the in-hospital mortality rate and functional outcomes during follow-up did not differ between COVID-CVT patients and the pre-COVID-19 controls.
19.	Vu, Xuan-Son, 1988-, et al. (författare) MC-OCR Challenge : Mobile-Captured Image Document Recognition for Vietnamese Receipts 2021 Ingår i: Proceedings - 2021 RIVF International Conference on Computing and Communication Technologies, RIVF 2021. - : IEEE. - 9781665404358 ; , s. 88-93 Konferensbidrag (refereegranskat)abstract The paper describes the organisation of the "Mobile Captured Receipt Recognition Challenge"(MC-OCR) task at the RIVF conference 2021 1 on recognizing the fine-grained information in Vietnamese receipts captured using mobile devices. The task is organized as a multi-tasking model on a dataset containing 2, 436 Vietnamese receipts. The participants were challenged to build a model that is capable of (1) predicting receipt's quality based on readable information, and (2) recognizing textual information of four required information (i.e., "SELLER", "SELLER ADDRESS", "TIMESTAMP", and "TOTAL COST") in the receipts. MC-OCR challenge happened in one month and top winners of each task will present their solutions at RIVF 2021. Participants were competing on CodaLab.Org from 05th December 2020 to 23rd January 2021. All participants with valid submitted results were encouraged to submit their papers. Within one month, the challenge has attracted 105 participants and recorded about 1, 285 submission entries.
20.	Berckx, Fede, 1993-, et al. (författare) A tale of two lineages : how the strains of the earliest divergent symbiotic Frankia clade spread over the world 2022 Ingår i: BMC Genomics. - : Springer Science and Business Media LLC. - 1471-2164. ; 23:1 Tidskriftsartikel (refereegranskat)abstract It is currently assumed that around 100 million years ago, the common ancestor to the Fabales, Fagales, Rosales and Cucurbitales in Gondwana, developed a root nodule symbiosis with a nitrogen-fixing bacterium. The symbiotic trait evolved first in Frankia cluster-2; thus, strains belonging to this cluster are the best extant representatives of this original symbiont. Most cluster-2 strains could not be cultured to date, except for Frankia coriariae, and therefore many aspects of the symbiosis are still elusive. Based on phylogenetics of cluster-2 metagenome-assembled genomes (MAGs), it has been shown that the genomes of strains originating in Eurasia are highly conserved. These MAGs are more closely related to Frankia cluster-2 in North America than to the single genome available thus far from the southern hemisphere, i.e., from Papua New Guinea.To unravel more biodiversity within Frankia cluster-2 and predict routes of dispersal from Gondwana, we sequenced and analysed the MAGs of Frankia cluster-2 from Coriaria japonica and Coriaria intermedia growing in Japan, Taiwan and the Philippines. Phylogenetic analyses indicate there is a clear split within Frankia cluster-2, separating a continental from an island lineage. Presumably, these lineages already diverged in Gondwana.Based on fossil data on the host plants, we propose that these two lineages dispersed via at least two routes. While the continental lineage reached Eurasia together with their host plants via the Indian subcontinent, the island lineage spread towards Japan with an unknown host plant.
21.	Hoa Nguyen, Tien, et al. (författare) Performance Analysis and Optimization of the Coverage Probability in Dual Hop LoRa Networks With Different Fading Channels 2020 Ingår i: IEEE Access. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 2169-3536. ; 8, s. 107087-107102 Tidskriftsartikel (refereegranskat)abstract In this work, the performance evaluation and the optimization of dual-hop LoRa network are investigated. In particular, the coverage probability (Pcov) of edge end-devices (EDs) is computed in closed-form expressions under various fading channels, i.e., Nakagami-m and Rayleigh fading. The Pcov under Nakagami-m fading is computed in the approximated closed-form expressions; the Pcov under Rayleigh fading, on the other hand, is calculated in the exact closed-form expressions. In addition, we also investigate the impact of different kinds of interference on the performance of the Pcov, i.e., intra-SF interference, inter-SF interference (or capture effect) and both intra- and inter-SF interference. Our findings show that the impact of imperfect orthogonality is not non-negligible, along with the intra-SF interference. Moreover, based on the proposed mathematical framework, we formulate an optimization problem, which finds the optimal location of the relay to maximize the coverage probability. Since it is a mixed integer program with a non-convex objective function, we decompose the original problem with discrete optimization variables into sub-problems with a convex feasible set. After that, each sub-problem is effectively solved by utilizing the gradient descent approach. Monte Carlo simulations are supplied to verify the correctness of our mathematical framework. In addition, the results manifest that our proposed optimization algorithm converges rapidly, and the coverage probability is significantly improved when the location of relay is optimized.
22.	Hoang, Thanh, 1992, et al. (författare) Factors Influencing Tobacco Smoking and Cessation Among People Living with HIV: A Systematic Review and Meta-analysis 2024 Ingår i: AIDS and Behavior. - 1090-7165 .- 1573-3254. Forskningsöversikt (refereegranskat)abstract Tobacco smoking is highly prevalent among people living with HIV (PLWH), yet there is a lack of data on smoking behaviours and effective treatments in this population. Understanding factors influencing tobacco smoking and cessation is crucial to guide the design of effective interventions. This systematic review and meta-analysis of studies conducted in both high-income (HICs) and low- and middle-income countries (LMICs) synthesised existing evidence on associated factors of smoking and cessation behaviour among PLWH. Male gender, substance use, and loneliness were positively associated with current smoking and negatively associated with smoking abstinence. The association of depression with current smoking and lower abstinence rates were observed only in HICs. The review did not identify randomised controlled trials conducted in LMICs. Findings indicate the need to integrate smoking cessation interventions with mental health and substance use services, provide greater social support, and address other comorbid conditions as part of a comprehensive approach to treating tobacco use in this population. Consistent support from health providers trained to provide advice and treatment options is also an important component of treatment for PLWH engaged in care, especially in LMICs.
23.	Kariippanon, Katharina E., et al. (författare) Levels and Correlates of Objectively Measured Sedentary Behavior in Young Children : SUNRISE Study Results from 19 Countries 2022 Ingår i: Medicine & Science in Sports & Exercise. - : Lippincott, Williams & Wilkins. - 0195-9131 .- 1530-0315. ; 54:7, s. 1123-1130 Tidskriftsartikel (refereegranskat)abstract Purpose There is a paucity of global data on sedentary behavior during early childhood. The purpose of this study was to examine how device-measured sedentary behavior in young children differed across geographically, economically, and sociodemographically diverse populations, in an international sample. Methods This multinational, cross-sectional study included data from 1071 children 3-5 yr old from 19 countries, collected between 2018 and 2020 (pre-COVID). Sedentary behavior was measured for three consecutive days using activPAL accelerometers. Sedentary time, sedentary fragmentation, and seated transport duration were calculated. Linear mixed models were used to examine the differences in sedentary behavior variables between sex, country-level income groups, urban/rural settings, and population density. Results Children spent 56% (7.4 h) of their waking time sedentary. The longest average bout duration was 81.1 +/- 45.4 min, and an average of 61.1 +/- 50.1 min center dot d(-1) was spent in seated transport. Children from upper-middle-income and high-income countries spent a greater proportion of the day sedentary, accrued more sedentary bouts, had shorter breaks between sedentary bouts, and spent significantly more time in seated transport, compared with children from low-income and lower-middle-income countries. Sex and urban/rural residential setting were not associated with any outcomes. Higher population density was associated with several higher sedentary behavior measures. Conclusions These data advance our understanding of young childrens sedentary behavior patterns globally. Country income levels and population density appear to be stronger drivers of the observed differences, than sex or rural/urban residential setting.
24.	Lam, Thanh Tu, et al. (författare) Performance Evaluation of Incremental Relaying in Underlay Cognitive Radio Networks with Imperfect CSI 2021 Ingår i: IEEE ICCE 2020: 2020 IEEE EIGHTH INTERNATIONAL CONFERENCE ON COMMUNICATIONS AND ELECTRONICS (ICCE). - : IEEE. - 9781728154718 ; , s. 472-477 Konferensbidrag (refereegranskat)abstract The performance of both primary and secondary networks in underlay cognitive radio networks (CRNs) with the help of incremental amplify and forward (IAF) relaying under imperfect channel state information (CSI) are investigated. Particularly, the interference probability at primary networks denoted by IP as well as the outage probability at secondary networks denoted by OP, are computed in the closed-form expressions. Our findings show that the impact of the imperfect CSI on the performance of IP is non-negligible. To tackle the high value of IP, reducing the transmit power at the secondary transmitters is a proper solution, it, however, will also increase the OP at the secondary networks. Thus, a simple power control coefficient is proposed to compromise the performance between two networks. Finally, Monte-Carlo simulations are provided to verify the accuracy of the proposed mathematical frameworks.
25.	Le, Phong Q., et al. (författare) Iodine-promoted amide formation via oxidative cleavage of indoles : novel quinazoline-4(3H)-one and tryptanthrin syntheses 2024 Ingår i: RSC Advances. - : Royal Society of Chemistry. - 2046-2069. ; 14:22, s. 15597-15603 Tidskriftsartikel (refereegranskat)abstract A highly efficient method for the direct construction of amide bonds via a selective cleavage of C-H and C=C bonds in indole structures using an iodine-promoted approach was developed. Mechanistic studies indicated the formation of superoxide radicals obtained from molecular oxygen activation as a key intermediate step, which provided a precursor for subsequent oxidative ring-opening and intermolecular cyclization. A broad range of quinazolin-4(3H)-ones and tryptanthrins were synthesized in moderate to good yields under mild and environmentally benign conditions.
26.	Marto, João Pedro, et al. (författare) Safety and Outcome of Revascularization Treatment in Patients With Acute Ischemic Stroke and COVID-19: The Global COVID-19 Stroke Registry. 2023 Ingår i: Neurology. - 1526-632X. ; 100:7 Tidskriftsartikel (refereegranskat)abstract COVID-19-related inflammation, endothelial dysfunction, and coagulopathy may increase the bleeding risk and lower the efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate the safety and outcomes of revascularization treatments in patients with AIS and COVID-19.This was a retrospective multicenter cohort study of consecutive patients with AIS receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 and June 2021 tested for severe acute respiratory syndrome coronavirus 2 infection. With a doubly robust model combining propensity score weighting and multivariate regression, we studied the association of COVID-19 with intracranial bleeding complications and clinical outcomes. Subgroup analyses were performed according to treatment groups (IVT-only and EVT).Of a total of 15,128 included patients from 105 centers, 853 (5.6%) were diagnosed with COVID-19; of those, 5,848 (38.7%) patients received IVT-only and 9,280 (61.3%) EVT (with or without IVT). Patients with COVID-19 had a higher rate of symptomatic intracerebral hemorrhage (SICH) (adjusted OR 1.53; 95% CI 1.16-2.01), symptomatic subarachnoid hemorrhage (SSAH) (OR 1.80; 95% CI 1.20-2.69), SICH and/or SSAH combined (OR 1.56; 95% CI 1.23-1.99), 24-hour mortality (OR 2.47; 95% CI 1.58-3.86), and 3-month mortality (OR 1.88; 95% CI 1.52-2.33). Patients with COVID-19 also had an unfavorable shift in the distribution of the modified Rankin score at 3 months (OR 1.42; 95% CI 1.26-1.60).Patients with AIS and COVID-19 showed higher rates of intracranial bleeding complications and worse clinical outcomes after revascularization treatments than contemporaneous non-COVID-19 patients receiving treatment. Current available data do not allow direct conclusions to be drawn on the effectiveness of revascularization treatments in patients with COVID-19 or to establish different treatment recommendations in this subgroup of patients with ischemic stroke. Our findings can be taken into consideration for treatment decisions, patient monitoring, and establishing prognosis.The study was registered under ClinicalTrials.gov identifier NCT04895462.
27.	Okely, Anthony D., et al. (författare) Cross-sectional examination of 24-hour movement behaviours among 3-and 4-year-old children in urban and rural settings in low-income, middle-income and high-income countries : the SUNRISE study protocol 2021 Ingår i: BMJ Open. - : BMJ Publishing Group Ltd. - 2044-6055. ; 11:10 Tidskriftsartikel (refereegranskat)abstract Introduction 24-hour movement behaviours (physical activity, sedentary behaviour and sleep) during the early years are associated with health and developmental outcomes, prompting the WHO to develop Global guidelines for physical activity, sedentary behaviour and sleep for children under 5 years of age. Prevalence data on 24-hour movement behaviours is lacking, particularly in low-income and middle-income countries (LMICs). This paper describes the development of the SUNRISE International Study of Movement Behaviours in the Early Years protocol, designed to address this gap. Methods and analysis SUNRISE is the first international cross-sectional study that aims to determine the proportion of 3- and 4-year-old children who meet the WHO Global guidelines. The study will assess if proportions differ by gender, urban/rural location and/or socioeconomic status. Executive function, motor skills and adiposity will be assessed and potential correlates of 24-hour movement behaviours examined. Pilot research from 24 countries (14 LMICs) informed the study design and protocol. Data are collected locally by research staff from partnering institutions who are trained throughout the research process. Piloting of all measures to determine protocol acceptability and feasibility was interrupted by COVID-19 but is nearing completion. At the time of publication 41 countries are participating in the SUNRISE study. Ethics and dissemination The SUNRISE protocol has received ethics approved from the University of Wollongong, Australia, and in each country by the applicable ethics committees. Approval is also sought from any relevant government departments or organisations. The results will inform global efforts to prevent childhood obesity and ensure young children reach their health and developmental potential. Findings on the correlates of movement behaviours can guide future interventions to improve the movement behaviours in culturally specific ways. Study findings will be disseminated via publications, conference presentations and may contribute to the development of local guidelines and public health interventions.
28.	Poli, Sven, et al. (författare) Penumbral Rescue by normobaric O?=?O administration in patients with ischemic stroke and target mismatch proFile (PROOF): Study protocol of a phase IIb trial 2024 Ingår i: INTERNATIONAL JOURNAL OF STROKE. - 1747-4930 .- 1747-4949. ; 19:1, s. 120-126 Tidskriftsartikel (refereegranskat)abstract Rationale: Oxygen is essential for cellular energy metabolism. Neurons are particularly vulnerable to hypoxia. Increasing oxygen supply shortly after stroke onset could preserve the ischemic penumbra until revascularization occurs.Aims: PROOF investigates the use of normobaric oxygen (NBO) therapy within 6 h of symptom onset/notice for brain-protective bridging until endovascular revascularization of acute intracranial anterior-circulation occlusion.Methods and design: Randomized (1:1), standard treatment-controlled, open-label, blinded endpoint, multicenter adaptive phase IIb trial.Study outcomes: Primary outcome is ischemic core growth (mL) from baseline to 24 h (intention-to-treat analysis). Secondary efficacy outcomes include change in NIHSS from baseline to 24 h, mRS at 90 days, cognitive and emotional function, and quality of life. Safety outcomes include mortality, intracranial hemorrhage, and respiratory failure. Exploratory analyses of imaging and blood biomarkers will be conducted.Sample size: Using an adaptive design with interim analysis at 80 patients per arm, up to 456 participants (228 per arm) would be needed for 80% power (one-sided alpha 0.05) to detect a mean reduction of ischemic core growth by 6.68 mL, assuming 21.4 mL standard deviation.Discussion: By enrolling endovascular thrombectomy candidates in an early time window, the trial replicates insights from preclinical studies in which NBO showed beneficial effects, namely early initiation of near 100% inspired oxygen during short temporary ischemia. Primary outcome assessment at 24 h on follow-up imaging reduces variability due to withdrawal of care and early clinical confounders such as delayed extubation and aspiration pneumonia.
29.	Ramachandran, Prashanth, et al. (författare) Abscisic acid signaling activates distinct VND transcription factors to promote xylem differentiation in Arabidopsis 2021 Ingår i: Current Biology. - : Cell Press. - 0960-9822 .- 1879-0445. ; 31:14, s. 3153-3161.e5 Tidskriftsartikel (refereegranskat)abstract Plants display remarkable abilities to adjust growth and development to environmental conditions, such as the amount of available water. This developmental plasticity is apparent not only in root and shoot growth rates, but also in tissue patterning and cell morphology.(1,2) We have previously shown that in response to limited water availability, Arabidopsis thaliana root displays changes in xylem morphology, mediated by the non-cell-autonomous action of abscisic acid, ABA.(2) Here, we show, through analyses of ABA response reporters and tissue-specific suppression of ABA signaling, that xylem cells themselves act as primary signaling centers governing both xylemcell fate and xylem differentiation rate, revealing the cell-autonomous control of multiple aspects of xylem development by ABA. ABA rapidly activates the expression of genes encoding VASCULAR-RELATED NAC DOMAIN (VND) transcription factors. Molecular and genetic analyses revealed that the two ABA-mediated xylem developmental changes are regulated by distinct members of this transcription factor family, with VND2 and VND3 promoting differentiation rate of metaxylem cells, while VND7 promotes the conversion of metaxylem toward protoxylem morphology. This phenomenon shows how different aspects of developmental plasticity can be interlinked, yet genetically separable. Moreover, similarities in phenotypic and molecular responses to ABA in diverse species indicate evolutionary conservation of the ABA-xylem development regulatory network among eudicots. Hence, this study gives molecular insights into how environmental stress modifies plant vascular anatomy and has potential relevance for water use optimization and adaptation to drought conditions.

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