| 1. |
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| 2. |
- Adiels, Lars, 1952-, et al.
(författare)
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Test of CP violation with K0 and K‾0 at LEAR
- 1985
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Ingår i: Physics with antiprotons at LEAR in the ACOL era. - Gif sur Yvette : Editions Frontières. - 2863320351 ; , s. 467-482
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 3. |
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| 4. |
- Anveskog, L., et al.
(författare)
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Att välja rätt standardsystem
- 1984
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Ingår i: Data (Nordisk datanytt), nr 10, 1984, sid. 50-52.
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Tidskriftsartikel (refereegranskat)abstract
- Vi står inför att välja standardsystem. Vårt mål är att standardsystemet skall ge ett effektivt bidrag till verksamheten. Syftet är också att tjäna tid och pengar jämfört med egenutveckling. Et sätt att välja är att köpa det standardsystem som vi omedelbart fastnar för. Risken är då att vi inte ser de svårigheter och nackdelar som ofta finns. Vi bländas lätt av de positiva möjligheter som erbjuds genom standardsystemet. Vi går in i valprocessen med en förutfattad mening.Ett alternativt sätt att välja är att mera noggrant jämföra tänkbara standardsystem mot den egna verksamheten. Vi behöver då ta ställning till en mångfald olika faktorer för att kunna välja "rätt" standardsystem. En systematisk metod hjälper oss att få en överblick. Vi får en säker grund att stå på för att dra riktiga slutsatser om standardsystemens möjligheter och brister
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| 5. |
- Anveskog, L., et al.
(författare)
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Development of Activities - Standard Application Packages according SIV to help you choose the right standard application package for your organization : Verksamhetsutveckling - Standardsystem enligt SIV för att du skall kunna välja rätt standardsystem för din verksamhet
- 1986
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The report is published in an English and Swedish version.Rapporten finns utgiven på svenska och engelska.------------------------------------------------There is a need for a systematic way of working when planning for standard application packages in organizations. We have tried to develop a method for this field - the SIV method (Standard Application Packages in Organizations, in Swedish: Standardsystem I Verksamheter). The SIV method takes the customer's situation as a starting point - a customer view. Furthermore, occasions have been described where a dialogue between the customer and the vendor is necessary, e.g. demonstrations and negotiations. The SIV method gives a survey of the field with emphasis on adaptation of activities and standard application packages to each other and choice of standard application packages.This report is focusing on "choice" of standard application packages. A similar report has been done for "adaptation" of standard application packages.------------------------------------------------ Det finns behov av ett systematiskt arbetssätt vid planering av standardsystem för verksamheter. Vi har försökt utveckla en metodik för detta område - SIV (Standardsystem I Verksamheter). SIV-metodiken tar utgångspunkt i kundens situation - ett kundperspektiv. Vidare anges tillfällen när det behövs en dialog mellan kund och leverantör, t.ex. demonstrationer och förhandlingar. SIV-metodiken ger en översikt av området med betoning på val och anpassning av standardystem mot varandra.Denna rapport behandlar "val" av standardsystem. En liknande rapport har tagits fram för "anpassning" av standardystem.------------------------------------------------
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| 6. |
- Anveskog, L., et al.
(författare)
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Verksamhetsutveckling - Att välja standardsystem
- 1984
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Bok (refereegranskat)abstract
- De flesta företag köper idag färdiga standardsystem, i stället för att programmera, när man datoriserar olika rutiner.Att välja system innebär att vi jämför företagets behov med vad som finns på marknaden. Arbetet kan ses som en beslutsprocess där vi successivt väljer bort standardsystem så att till slut det "bästa" alterntivet återstår. Boken presenterar en metod för bättre planering av Standardsystem I Verksamheter (SIV) med tonvikt på valproblematiken. SIV-metoden omfattar ett antal steg, behovsnanalys, förutsättningsanalys, markandsundersökning, leverantörsbedömning, offertbegäran, jämförelse, urval, demonstration, behovskomplettering, utvärdering, preliminärval, testkörning, förhandling, beslut och delgivning.Ibland behöver vi ändå förändra standardsystemet och/eller den egna verksamheten. En metod för detta presenteras i boken: " Verksamhetsutveckling - Att anpassa standardsystem" (Studenlitteratur, 1983) som kan ses som ett komplement till denna bok.Boken var förpublicerad som V-rapport V-4302, Institutet för Verksamhetsutveckling (Institut V) vid Handelshögskolan i Stockholm (1983-12-01)
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| 7. |
- de Luca, S., et al.
(författare)
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Proteoglycans from chick limb bud chondrocyte cultures. Keratan sulfate and oligosaccharides which contain mannose and sialic acid
- 1980
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Ingår i: Journal of Biological Chemistry. - 0021-9258. ; 255:13, s. 6077-6083
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Tidskriftsartikel (refereegranskat)abstract
- The precursors, [ 35S]sulfate and [2- 3H]mannose, were used to study the biosynthesis of keratan sulfate and other oligosaccharides on proteoglycans isolated from Day 8 cultures of chick limb bud chondrocytes. After alkaline borohydride treatment, three fractions with sialic acid were separated by molecular sieve chromatography. The first contained keratan sulfate which was purified by digestion with chondroitinase to remove chondroitin sulfate, followed by molecular sieve and ion exchange chromatography. The purified keratan sulfate contained about 8% of the 35S activity originally in monomer. The chains had an average length of about 40 monosaccharides and contained only trace amounts of mannose (less than 1 residue/three to four chains). The second fraction contained the majority of the [ 3H]mannose originally in monomer, but no 35S activity. This fraction appears to contain oligosaccharide-peptides of the asparagine-N-glycosylamine type because there were no reduced sugars present and the alkaline borohydride treatment extensively degraded the core protein. The composition of the oligosaccharides, with high proportions of mannose, N-acetylglucosamine, galactose, and sialic acid, was consistent with this suggestion. The third fraction consisted of a series of oligosaccharides with sizes between three to six saccharides. They contained N-acetylgalactosaminitol, indicating that they were attached to the core protein by O-glycoside bonds between N-acetylgalactosamine and hydroxyl groups on serine and threonine. Thus, proteoglycans contain two classes of oligosaccharides, a mannose-rich class characteristic of glycoproteins and an O-glycoside class characteristic of mucins, in addition to the chondroitin sulfate and keratan sulfate chains.
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| 8. |
- Erlinge, S, et al.
(författare)
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Predation on brown hare and ring-necked pheasant populations on southern Sweden
- 1984
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Ingår i: Holarctic Ecology. ; 7:3, s. 300-304
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Tidskriftsartikel (refereegranskat)abstract
- in an open field area in southern Sweden. Biomass and numbers of hares and pheasants eaten by the predators were calculated from data on food habits, food requirements, and numbers of the mammalian and avian predators present (11 species). At the same time estimates of numbers and production of hares and pheasants were obtained. At least 40% of the estimated annual production of hares and almost 60% of subadult-adultp heasants in autumn were consumed by the predators. Estimated numbers of hares and pheasants taken by the predators greatly exceeded shootinga nd road mortality.F oxes and cats were the predominantp reda-tors on hares( about9 0%o f total harec onsumption). Foxesa ccountedf or aboutt wo-thirds of predation on pheasants; cats and goshawks were of secondary importance. Pheasant nests were preyed upon by hooded crows and also by badgers. Hares and pheasantsc ontributedo nly about 3 and 1%, respectively,o f the food of the predators.
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| 9. |
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| 10. |
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| 11. |
- Harris, A.S., et al.
(författare)
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Effect of viscosity on the pharmacokinetics and biological response to intranasal desmopressin.
- 1989
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Ingår i: Journal of Pharmaceutical Sciences. - : Elsevier BV. - 0022-3549. ; 78:6, s. 470-471
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Tidskriftsartikel (refereegranskat)abstract
- he effect of viscosity on the nasal absorption and biological response to desmopressin was studied in humans. Nasal solutions of desmopressin with and without the addition of 0.25% (w/v) methylcellulose were administered by a precompression nasal spray pump to 10 volunteers. Plasma levels of desmopressin were assayed by radioimmunoassay and the biological response was measured by determination of the antihemophilia factors (Factor VIII and von Willebrand factor). The results showed that the addition of methylcellulose produced a more sustained and slower absorption, with a longer time to maximum plasma concentration (tmax). However, the areas under the plasma concentration—time curve were not different, indicating a similar total bioavailability. The biological response showed a similar effect. Peak Factor VIII activity was not different, but the presence of methylcellulose produced a slower onset of activity. These findings indicate that although the addition of a viscous agent to nasal formulations may produce a more sustained effect, it delays the onset of activity and no enhancement is achieved in the total bioavailability.
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| 12. |
- Levin, J.C., et al.
(författare)
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Production of very cold, highly charged ions by synchrotron radiation: Comparisons of the “scalpel” and “hammer” methods
- 1987
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Ingår i: Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. - : Elsevier BV. - 0168-9002. ; 262:1, s. 106-109
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Tidskriftsartikel (refereegranskat)abstract
- Measurements of kinetic energies of highy charged argon ions produced by inner-shell photoionization and by ion-beam impact have been made using time-of-flight techniques. High-charge-state recoil ions produced by beams of ∼ 0.5-1 MeV/u Cl5+ are found to have energies one to two orders of magnitude higher than ions of the same charge produced by vacancy cascades following inner-shell photoionization by synchrotron radiation. The results may have application to the development of a very cold ion source useful for angle-resolved atomic collision studies.
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| 13. |
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| 14. |
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| 15. |
- Nilsson, I, et al.
(författare)
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Denitrification of Water Using Immobilized Pseudomonas denitrificans Cells
- 1980
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Ingår i: European Journal of Applied Microbiology and Biotechnology. ; 10, s. 261-274
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Tidskriftsartikel (refereegranskat)abstract
- Preparations of living Pseudomonas denitrificans cells immobilized in alginate gel were used in the denitrification of water. In the presence of an exogenous carbon source the entrapped microorganisms reduced nitrate and nitrite to gaseous products and to achieve complete reduction, carbon to nitrogen ratios of over two were required. The effects on denitrification of particle size and the number of bacteria in the gel were investigated. Apparent Km values for nitrate and nitrite reduction were calculated for free and immobilized cells. When the immobilized cells were incubated in nutrient media, an increase in reduction rate was observed and this was shown to be caused by the growth of cells within the gel particles. Immobilized P. denitrificans cells retained 75% of their initial nitrate reduction capacity after 21 days of storage at +4°C. The operational stability of the alginate-immobilized cells was studied both in batch and in a column which was operated continuously. A column (45 g of alginate-cell fibers in 80 ml) denitrified a high nitrate drinking water (100 mg NO3/l) with a rate of 300 ml of nitrate and nitrite free water/day/g of gel. The half life for nitrate reduction was estimated to be 30 days.
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| 16. |
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| 17. |
- Nilsson, I. M., et al.
(författare)
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Suppression of Secondary Antibody Response by Intravenous Immunoglobulin in a Patient with Haemophilia B and Antibodies
- 1983
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Ingår i: Scandinavian Journal of Haematology. - : Wiley. - 0036-553X. ; 30:5, s. 458-464
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Tidskriftsartikel (refereegranskat)abstract
- A 39‐year‐old patient, suffering from severe haemophilia B and antibodies against factor IX, has twice been treated with extracorporeal protein A‐Sepharose adsorption followed by conventional substitution therapy in combination with immunosuppression (cyclophos‐phamide). On both occasions, separated by a 2‐year interval, the same procedure was followed except that, on the second, administration of i.v. immunoglobulin (Gammonativ, KabiVitrum) was added. Within a week of the first treatment the patient developed a 15‐fold increase in the antibody titre. Following the second treatment described here, no secondary antibody response could be detected, and after a further 12 weeks only traces of antibodies are demonstrable. It seems that antibody synthesis was suppressed by the i.v. immunoglobulin. No evidence was found to demonstrate that the effect was due either to a non‐specific suppression of the immune and reticuloendothelial systems or to the action of interfering antibodies. It has not yet been established whether or not the protein A‐Sepharose adsorption technique, or the immunosuppressive treatment, contributed in any way to the result. The observations suggest a new approach to the treatment of haemophiliacs with antibodies of the high‐responding type.
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| 18. |
- Odenholt, I, et al.
(författare)
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Postantibiotic and bactericidal effect of imipenem against Pseudomonas aeruginosa.
- 1989
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Ingår i: European Journal of Clinical Microbiology and Infectious Diseases. - 0934-9723 .- 1435-4373. ; 8:2, s. 136-141
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Tidskriftsartikel (refereegranskat)abstract
- The postantibiotic effect of imipenem on Pseudomonas aeruginosa was studied at different inocula using one ATCC strain and four clinical isolates. The postantibiotic effect was measured using two different methods: viable counts and bioluminescence assay of intracellular bacterial ATP. The postantibiotic effect could be demonstrated with both methods (viable counts 1-2 h, ATP assay 3-5 h) for all strains at an inoculum of 10(6) CFU/ml. When the inoculum was raised to 10(8) CFU/ml, no postantibiotic effect could be observed with either method using routine growth conditions. This disappearance of the postantibiotic effect coincided with a loss of bactericidal effect of imipenem when high inocula were used. Improved oxygenation of the cultures restored the bactericidal and postantibiotic effects of imipenem at high inocula.
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| 19. |
- Paulsen, Otto, et al.
(författare)
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The interaction of erythromycin with theophylline
- 1987
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Ingår i: European Journal of Clinical Pharmacology. - 0031-6970. ; 32:5, s. 8-493
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Tidskriftsartikel (refereegranskat)abstract
- We have studied the interaction of erythromycin with theophylline. We gave ten healthy volunteers theophylline as an intravenous loading dose (5 mg X kg-1) over 1 h, followed by a maintenance infusion (0.5 mg X kg-1 X h-1) for 5 h. A second infusion of theophylline was given after 9 days of treatment with 1 g erythromycin base daily, and the concentrations of theophylline were determined during the infusion periods. The concentrations of erythromycin were measured for 8 h, after one week of treatment, and also after the last erythromycin dose, simultaneously with the second theophylline infusion. Concentrations within the therapeutic range were obtained with both drugs. A significant increase in both AUC and mean plasma concentrations of theophylline was seen during erythromycin treatment. The plasma clearance of theophylline was reduced in 9 of the 10 subjects. Renal clearance increased correspondingly, but the change was not statistically significant. Serum concentrations of erythromycin fell significantly, by more than 30%, with concurrent theophylline medication. We conclude that an interaction between theophylline and erythromycin, affecting both drugs, can be shown with concentrations of the drugs within the therapeutic range.
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| 20. |
- Reistad, N., et al.
(författare)
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Lifetimes of levels in cll and o iii, derived from beam-foil experiments and extensive cascade analyses
- 1986
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Ingår i: Physica Scripta. - : IOP Publishing. - 0031-8949 .- 1402-4896. ; 34:2, s. 151-157
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Tidskriftsartikel (refereegranskat)abstract
- Using the beam-foil excitation technique and the ANDC method for cascade corrections, we have determined lifetimes of the 2s2p22S, 2s2ns2S (n = 3, 4, 5), 2s2p22P, 2s2p2P° (n = 3, 4), and 2p32P° terms in CII and the 2s2p1P0 level in C III. The new experimental lifetimes are in very good agreement with the results of recent theoretical calculations.
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| 21. |
- Short, R. T., et al.
(författare)
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Production of very-low-energy highly charged ions by synchrotron radiation
- 1986
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Ingår i: Physical Review Letters. - 1079-7114. ; 56:24, s. 2614-2617
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Tidskriftsartikel (refereegranskat)abstract
- Very-low-energy highly charged ions have been produced by use of white and monochromatic x rays from a wiggler line at the Stanford Synchrotron Radiation Laboratory to generate vacancy cascades following inner-shell photoionization. Recoil-ion energies have been determined and are shown to correspond essentially to room temperatures, even for high charge states. Promising applications to study of the interaction of stellar radiation with cold matter, to high-brightness ionsource development, to precision spectroscopy, and to angle-resolved chemical-physics reactive-scattering studies are discussed.
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| 22. |
- Wallmark, A., et al.
(författare)
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Determination of factor IX allotypes for carrier identification in haemophilia B
- 1987
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Ingår i: British Journal of Haematology. - : Wiley. - 0007-1048 .- 1365-2141. ; 67:4, s. 427-432
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Tidskriftsartikel (refereegranskat)abstract
- The existence of two genetic variants (allotypes) of normal human factor IX is used for carrier detection in three families with severe and one with mild haemophilia B. By analysis of IX:Ag with two different monoclonal antibodies in 93 members of the families, allelic assignment is shown to be a complement in carrier diagnosis to genotypic DNA studies. Allelic assignment makes possible a reliable diagnosis based on phenotypic studies, though its usefulness is limited due to ethnic variation in allelic frequency. Determination of factor IX allotypes should be useful for carrier detection in any Swedish families with haemophilia B.
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| 23. |
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