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| 6. |
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| 7. |
- Stenman, U H, et al.
(författare)
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Summary report of the TD-3 workshop: characterization of 83 antibodies against prostate-specific antigen
- 1999
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Ingår i: Tumor Biology. - : Springer Science and Business Media LLC. - 1423-0380 .- 1010-4283. ; 20:Suppl. 1, s. 1-12
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Tidskriftsartikel (refereegranskat)abstract
- Twelve research groups participated in the ISOBM TD-3 Workshop in which the reactivity and specificity of 83 antibodies against prostate-specific antigen (PSA) were investigated. Using a variety of techniques including cross-inhibition assays, Western blotting, BIAcore, immunoradiometric assays and immunohistochemistry, the antibodies were categorized into six major groups which formed the basis for mapping onto two- and three-dimensional (2-D and 3-D) models of PSA. The overall findings of the TD-3 Workshop are summarized in this report. In agreement with all participating groups, three main antigenic domains were identified: free PSA-specific epitopes located in or close to amino acids 86-91; discontinuous epitopes specific for PSA without human kallikrein (hK2) cross-reactivity located at or close to amino acids 158-163; and continuous or linear epitopes shared between PSA and hK2 located close to amino acids 3-11. In addition, several minor and partly overlapping domains were also identified. Clearly, the characterization of antibodies from this workshop and the location of their epitopes on the 3-D model of PSA illustrate the importance of selecting appropriate antibody pairs for use in immunoassays. It is hoped that these findings and the epitope nomenclature described in this TD-3 Workshop are used as a standard for future evaluation of anti-PSA antibodies.
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| 10. |
- Nilsson, Thomas, 1965, et al.
(författare)
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Neutron Momentum Distributions from Core Break-up Reactions of Halo Nuclei
- 1995
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Ingår i: Europhysics Letters. - 0295-5075 .- 1286-4854. ; 30:1, s. 19-24
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Tidskriftsartikel (refereegranskat)abstract
- Neutron angular distributions from violent break-up reactions of Li-11 and Be-11 have been measured at 28 MeV/u and 280 MeV/u and at 41 MeV/u and 460 MeV/u, respectively. The derived neutron momentum distributions show a narrow component in transverse momentum that is within uncertainties independent of beam energy and target charge. This component is suggested to be simply related to the momentum distribution of the loosely bound halo neutron(s) in the projectiles.
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| 11. |
- Aleksandrov, D., et al.
(författare)
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Invariant mass spectrum and alpha-n correlation function studied in the fragmentation of He-6 on a carbon target
- 1998
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Ingår i: Nuclear Physics A. - 0375-9474. ; 633:2, s. 234-246
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Tidskriftsartikel (refereegranskat)abstract
- Momentum distributions and invariant mass spectra from the breakup of He-6 ions with an energy of 240 MeV/u interacting with a carbon target have been studied. The data were used to extract information about the reaction mechanism which is influenced by the structure of He-6. It is found that the dominant reaction mechanism is a two-step process: knock out of one neutron followed by the decay of the He-5 resonance. The shape of the (alpha+n) two-body invariant mass spectrum is interpreted as mainly reflecting the 5He ground state which is a J(pi) = 3/2(-) resonance. However, no evidence for correlations between cu particles and neutrons is observed in the momentum widths of the distributions. It is demonstrated that a combined analysis of the two-body invariant mass spectrum and an appropriate correlation function may be used to determine the properties of the intermediate resonance. (C) 1998 Elsevier Science B.V.
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| 12. |
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| 13. |
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| 14. |
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| 15. |
- Chulkov, L. V., et al.
(författare)
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Large spin alignment of the unbound He-5 fragment after fragmentation of 240 MeV/nucleon He-6
- 1997
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Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 79:2, s. 201-204
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Tidskriftsartikel (refereegranskat)abstract
- Peripheral fragmentation of a 240 MeV/nucleon beam of the halo nucleus He-6 incident on carbon target has been studied in a kinematically complete experiment. It is found that one-neutron stripping to the unbound nucleus He-5 is the dominant fragmentation mechanism and that it leads to a spin alignment of He-5 in a plane perpendicular to the He-5 momentum vector. This is expected to be a common feature for all neutron halo nuclei.
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| 16. |
- Humbert, F., et al.
(författare)
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Longitudinal and Transverse-Momentum Distributions of Li-9 Fragments from Break-up of Li-11
- 1995
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Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - 0370-2693. ; 347:3-4, s. 198-204
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Tidskriftsartikel (refereegranskat)abstract
- Transverse and longitudinal momentum distributions of Li-9 fragments from Li-11 break-up reactions in C, Al and Pb targets have been measured at 280 MeV/u. The two-neutron removal cross-section was measured to be sigma(-2n), = 0.26 +/- 0.02 b for the carbon target, sigma(-2n) = 0.47 +/- 0.08 b for the aluminum target and sigma(-2n), = 1.9 +/- 0.4 b for the lead target. No significant difference is observed between the narrow widths (FWHM approximate to 47 MeV/c) of the transverse and longitudinal momentum distributions of the Li-9 fragments. The physical implications of this are discussed.
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| 17. |
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| 18. |
- Marques, F. M., et al.
(författare)
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Neutrons from the breakup of C-19
- 1996
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Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - 0370-2693. ; 381:4, s. 407-412
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Tidskriftsartikel (refereegranskat)abstract
- Neutrons arising from the breakup of a 30 MeV/nucleon C-19 beam on a tantalum target have been measured using the 98 element array DEMON. A narrow, forward peaked neutron angular distribution, with a corresponding momentum spread considerably smaller than those measured simultaneously for N-21, O-22 and F-24 was observed for charged fragments with Z
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| 19. |
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| 21. |
- Axelsson, L., et al.
(författare)
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Study of the unbound nucleus 11N by elastic resonance scattering
- 1996
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Ingår i: Physical Review C (Nuclear Physics). - 0556-2813 .- 2469-9985 .- 2469-9993. ; 54:4, s. 1511-1514
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Tidskriftsartikel (refereegranskat)abstract
- Resonances in the unbound nucleus 11N have been studied, using the resonance scattering reaction 10C+p. The data give evidence for three states above the 10C+p threshold with energies 1.30, 2.04, and 3.72 MeV. These states can be interpreted, in a potential-model analysis, as the ground state and the first two excited states with spin-parity 1 / 2+, 1 / 2-, and 5 / 2+ arising from the shell-model orbitals 1s1 / 2, 0p1 / 2, and 0d5 / 2. A narrow state superposed on a broad structure found at higher energy could be interpreted as the mirror state of the 3 / 2- in 11Be shifted down in energy. This shift would suggest a large radius of the potential.
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| 22. |
- Baumann, T., et al.
(författare)
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Longitudinal momentum distributions of C-16,C-18 fragments after one-neutron removal from C-17,C-19
- 1998
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Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - 0370-2693. ; 439:3-4, s. 256-261
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Tidskriftsartikel (refereegranskat)abstract
- The fragment separator FRS at GSI was used as an energy-loss spectrometer to measure the longitudinal momentum distributions of C-16,C-18 fragments after one-neutron removal reactions in C-17,C-19 impinging on a carbon target at about 910 MeV/u. The distributions in the projectile frames are characterized by a FWHM of 141 +/- 6 MeV/c for C-16 and 69 +/- 3 MeV/c for C-18. Th, results are compared with experimental data obtained at lower energies and discussed within existing theoretical models. (C) 1998 Elsevier Science B.V. AU rights reserved.
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| 23. |
- Fynbo, H. O. U., et al.
(författare)
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Ar-31 examined: New limit on the beta-delayed three-proton branch
- 1999
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Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993. ; 59:4, s. 2275-2277
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Tidskriftsartikel (refereegranskat)abstract
- We have remeasured the decay of Ar-31 with a setup sensitive to multiparticle decay branches and obtained. a new limit of 1.1 x 10(-3) (99% C.L.) on the beta-delayed three-proton branch between the isobaric analog state in Cl-31 and the ground state of Si-28. This a factor of 17 below the previously reported first observation of beta-delayed three-proton emission in Ar-31. The limit on a possible beta 3p branch to the first excited state in Si-28 is 2.9 x 10(-4). [S0556-2813(99)04404-0].
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| 24. |
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| 25. |
- Hakansson, M C, et al.
(författare)
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The electronic structure of In- and As-terminated InAs(001) surfaces
- 1997
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Ingår i: Surface Science. - 0039-6028 .- 1879-2758. ; 374:1-3, s. 73-79
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Tidskriftsartikel (refereegranskat)abstract
- The InAs(001) 2 x 4 and 4 x 2 surfaces have been investigated by angle-resolved photoemission. The X(3) and X(5) points were found to be located 6.0 and 2.7 eV below the valence band maximum, respectively, and the dispersion of bulk bands along the Gamma-X direction in the bulk Brillouin zone were well described by a theoretical calculation. From angle-resolved valence band spectra measured along the high symmetry directions [110] and [1(1) over bar0$], three surface induced stares were identified on both the InAs(001)4 x 2 and the InAs(001)2 x 4 surface. (C) 1997 Elsevier Science B.V.
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| 26. |
- Nilsson, Thomas, 1965, et al.
(författare)
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He-6 and neutron momentum distributions from He-8 in nuclear break-up reactions at 240 MeV/u
- 1996
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Ingår i: Nuclear Physics A. - 0375-9474. ; 598:3, s. 418-434
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Tidskriftsartikel (refereegranskat)abstract
- Neutron and He-6 momentum distributions from He-8 break-up reactions in a C target have been measured at 240 MeV/u. The two-neutron removal cross section was found to be sigma(-2n) = 0.27 +/- 0.03 b. The nature of the momentum distributions is interpreted in some simple reaction scenarios.
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| 27. |
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| 28. |
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| 29. |
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| 30. |
- Andersson, C B M, et al.
(författare)
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Surface atomic structure of InAs((111)over-bar)2x2 and InSb((111)over-bar)2x2 studied by core level spectroscopy
- 1996
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Ingår i: Surface Science. - : Elsevier BV. - 0039-6028 .- 1879-2758. ; 347:1-2, s. 199-206
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Tidskriftsartikel (refereegranskat)abstract
- Surface sensitive high resolution core level spectroscopy has been applied to the molecular beam epitaxy grown InAs((111) over bar)2 x 2 and InSb((111) over bar)2 x 2 surfaces. For both systems the In 4d core level consists of one dominating component while the Group V core levels are deconvoluted into four components. This analysis is consistent with a surface model where the topmost layer consists entirely of arsenic or antimony. In this model, Group V atoms form trimers bound to Group V atoms in the first double layer, leaving a single Group V rest atom per unit cell.
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| 31. |
- Axelsson, L., et al.
(författare)
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Beta decay of Ar-31
- 1998
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Ingår i: Nuclear Physics A. - 0375-9474. ; 634:4, s. 475-496
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Tidskriftsartikel (refereegranskat)abstract
- A complete study of Ar-31 beta decay has been made by high-resolution charged-particle and gamma-ray spectroscopy. Beta-delayed radiation was detected by an array of three charged-particle detectors and a large-volume germanium detector. Fifteen new energy levels were discovered in Cl-31. The beta-strength distribution, measured to 14.5 MeV, is compared with a shell-model calculation in the full sd space. The quenching of the Gamow-Teller strength and the isospin impurity of the IAS in Cl-31 are discussed. (C) 1998 Published by Elsevier Science B.V.
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| 32. |
- Axelsson, L., et al.
(författare)
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Two-proton emission in the decay of Ar-31
- 1998
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Ingår i: Nuclear Physics A. - 0375-9474. ; 628:3, s. 345-362
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Tidskriftsartikel (refereegranskat)abstract
- Several beta-delayed two-proton branches were observed in the decay of Ar-31, the most intense ones proceeding through the isobaric analogue state (IAS) in Cl-31. The mechanism of the two-proton emission is studied via the energy and angular distributions of the two protons, Simultaneous emission of the two protons fits the present data well, sequential decays might also describe them. Independent of the decay mechanism, a spin of 5/2 for the IAS is suggested, An improved limit on the direct two-proton emission fi om the ground state of Ar-31 is presented, (C) 1998 Elsevier Science B.V.
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| 33. |
- Echternach, P. M., et al.
(författare)
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Effect of non-classical current paths in networks of 1-dimensional wires
- 1996
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Ingår i: Czechoslovak Journal of Physics. - 0011-4626.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- At low temperatures, the quantum corrections to the resistance due to weak localization and electron-electron interaction are affected by the shape and topology of samples. We observed these effects in the resistance of 2D percolation networks made from 1D wires and in a series of long 1D wires with regularly spaced side branches. Branches outside the classical current path strongly reduce the quantum corrections to the resistance and these reductions become a measure of the quantum lengths
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| 34. |
- FUHRBERG, K, et al.
(författare)
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COMPTON-SCATTERING OF 87 MEV PHOTONS BY HE-4
- 1995
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Ingår i: NUCLEAR PHYSICS A. - : ELSEVIER SCIENCE BV. ; 591:1, s. 1-14
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Differential cross sections for Compton scattering by He-4 have been measured at photon energies ranging from 83.7 to 93.8 MeV with a weighted average of 87 MeV using the bremsstrahlung beam of the MAX-LAB (Lund) nuclear-physics facility. The experimental
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| 35. |
- Gershenson, M. E., et al.
(författare)
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Nonlocal effects in the resistance of one-dimensional wires with dangling side branches
- 1995
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Ingår i: Physical Review B. - 2469-9969 .- 2469-9950. ; 51, s. 10256-9
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Tidskriftsartikel (refereegranskat)abstract
- We have studied the quantum corrections to the resistance of one-dimensional gold wires with periodically spaced dangling side branches. Both the weak localization and interaction corrections to the resistance of such samples are strongly reduced when the distance between branches becomes smaller than the quantum length scales. The dependence of the quantum corrections on the distance between the branches then becomes a measurement of the quantum lengths
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| 36. |
- Gershenson, M. E., et al.
(författare)
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Quantum effects in the resistivity of percolation metal networks
- 1995
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Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 74, s. 446-9
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Tidskriftsartikel (refereegranskat)abstract
- We have studied the quantum corrections to the resistance of two-dimensional (2D) percolation networks of quasi-one-dimensional (1D) wires in which the ratio between the percolation correlation length and the quantum lengths L,LT could be controllably changed over a wide range. We have shown that the percolation networks behave like homogeneous 2D conductors with respect to the quantum corrections if L, LT. Close to the percolation threshold (L, LT) a crossover to 1D quantum corrections is observed
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| 37. |
- Lindgren, S., et al.
(författare)
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Laser flip-chip mounting for passive alignment and high-frequency modulation
- 1996
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Ingår i: Optical Communication, 1996. ECOC ’96. 22nd European Conference on. ; , s. 103-106
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Konferensbidrag (refereegranskat)abstract
- We have developed a silicon motherboard for flip-chip mounting of lasers in a way that is compatible with high-frequency modulation (24 GHz) and which allows passive alignment of the lasers to single-mode fibres.
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| 38. |
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| 39. |
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| 40. |
- Nilsson, G., et al.
(författare)
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Demonstration of mast-cell chemotactic activity in nasal lavage fluid : characterization of one chemotaxin as c-kit ligand, stem cell factor
- 1998
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Ingår i: Allergy. European Journal of Allergy and Clinical Immunology. - : Wiley. - 0105-4538 .- 1398-9995. ; 53:9, s. 874-879
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Tidskriftsartikel (refereegranskat)abstract
- Mast cells are known to accumulate in tissue during allergic inflammation. However, the chemotaxins responsible are undefined. Using a modified Boyden chamber and the human mast-cell line HMC-1, we first identified mast-cell chemotactic activity in nasal lavage fluid collected before the pollen season after allergen provocation of allergic patients (n=29) (mean migratory response compared to medium control was 121%, range 85-198%). Mast-cell chemotactic activity was also detected in lavage fluid collected after allergen provocation at the end of a Swedish birch-pollen season from three different treatment groups: topical steroid treatment with budesonide; the topical antihistamine, levocabastine; and placebo. There was no significant difference in mast-cell chemotactic activity between nasal lavage fluid collected from the placebo group (mean=102%), the budesonide-treated group (mean=114%), or the levocabastine group (mean=125%). Stem cell factor (SCF), a known mast-cell chemotaxin, was present in the nasal lavage fluids from all three groups, and correlated with the mast-cell chemotactic activity (r=0.67, P<0.01). The mast-cell chemotactic activity was inhibited (range 5-100%) in some, but not all, nasal lavage fluids by a polyclonal antibody directed against SCF. This report describes the presence of mast-cell chemotactic activity in nasal lavage fluid during an allergic reaction. These findings show that SCF may play a pivotal role in the recruitment of mast cells in allergic rhinitis.
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| 41. |
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| 42. |
- Olsson, L O, et al.
(författare)
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Core level and valence-band studies of the (111)2x2 surfaces of InSb and InAs
- 1996
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Ingår i: Physical Review B Condensed Matter. - 0163-1829 .- 1095-3795. ; 53:8, s. 4734-4740
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Tidskriftsartikel (refereegranskat)abstract
- The valence and core electronic surface states on the (111)2X2 surfaces of InSb and InAs have been studied by angle-resolved photoelectron spectroscopy. Similarities in data show that the vacancy-buckling model, which is known to describe the InSb(111)2x2 surface, also applies to InAs(111)2X2. Three surface valence bands are identified and their dispersions are mapped along symmetry directions in the surface Brillouin zone. The In 4d core levels show one surface shifted component while no surface shifted components of the Sb 4d or As 3d core levels could be resolved.
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| 43. |
- Rojas, Ana Maria, et al.
(författare)
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Nicotinamide as a repair inhibitor in vivo: single and fractionated X-ray dose studies in mouse skin and kidneys
- 1996
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Ingår i: Radiation Research. - 0033-7587 .- 1938-5404. ; 145:4, s. 419-431
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Tidskriftsartikel (refereegranskat)abstract
- Inhibitors of adenosine diphosphoribosyl transferase, like nicotinamide, 3-aminobenzamide and other analogues, can inhibit repair of radiation-induced sublethal and/or potentially lethal damage in some in vitro systems. Therefore, we have tested the effect of nicotinamide on repair parameters in vivo in two rodent normal tissues. In skin, the sensitivity to dose fractionation (1, 2, 5 or 10 X-ray fractions in 5 days) was monitored by defining the alpha/beta ratio in the presence or absence of nicotinamide (0.5 mg g-1) in air or carbogen. Pre- and postirradiation sensitization were investigated using an X-ray schedule of 5 fractions/5 days in carbogen alone or combined with nicotinamide given 1 h before, immediately after or 8 h after irradiation. Also, changes in the steepness of the underlying X-ray survival curve for the target skin clonogens, reflected by a change in the alpha/beta ratio, were investigated using the neutron top-up design. Underlying survival curves for oxygen +/- nicotinamide were obtained over the X-ray dose range 2.5 to 25 Gy, by administering single X-ray doses and following these with single top-up doses of d(4)-Be neutrons. Finally, in mouse kidney, recovery half-times (t1/2) were obtained by determining the time-dependent disappearance of X-ray damage using a split-dose design of two 6-Gy fractions separated by an interval which varied from 0 to 48 h and followed by two top-up doses from a neutron beam. No increase in alpha/beta for epidermal damage was seen with nicotinamide alone and, although sensitization was observed when the drug was given 1 h before irradiation, no postirradiation sensitization was detected. In kidney, there was no significant difference in the proportion of total repairable damage or in the half-life of recovery between treatments given with or without nicotinamide. Therefore, no decrease in normal tissue tolerance should be observed with the use of nicotinamide in clinical radiotherapy resulting either from reduced sparing with dose fractionation or from an increase in residual damage when shortening the interfraction interval. Finally, unless repair of radiation damage in normal tissues in vivo differs markedly from that of tumors, it is unlikely that the large sensitization seen in rodent tumors at 1.5 to 2 Gy per fraction, with carbogen and nicotinamide, can be attributed to nicotinamide acting as a repair inhibitor.
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| 45. |
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| 46. |
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| 47. |
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| 48. |
- Borge, M. J. G., et al.
(författare)
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Probing the Li-11 halo structure through beta-decay into the Be-11(*) (18 MeV) state
- 1997
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Ingår i: Nuclear Physics A. - 0375-9474. ; 613:3, s. 199-208
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Tidskriftsartikel (refereegranskat)abstract
- An experimental study of beta-delayed charged particles (H, He, Be) from Li-11 shows a beta-feeding to an excited state at 18.15(15) MeV in Be-11 with a large Gamow-Teller strength, B-GT greater than or equal to 1.6. Branching ratios and reduced widths of 2-, 3- and 5- particle decay channels of this state are extracted, A strong suppression of the neutron branch from the 18 MeV state to the Be-10(g.s.) is observed, We suggest that the measured partial width may be sensitive to the (p(1/2))(2) component in the Li-11 halo, A rough estimate indicates that the (p(1/2))(2) component is not the dominant one in the halo wave-function.
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| 49. |
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| 50. |
- Grevy, S., et al.
(författare)
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Core-breakup reactions of the halo nuclei Be-11 and Li-11: momentum distributions and shadow effects
- 1999
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Ingår i: Nuclear Physics A. - 0375-9474. ; 650:1, s. 47-61
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Tidskriftsartikel (refereegranskat)abstract
- The halo nuclei Be-11 and Li-11 have been studied in core-breakup reactions where the halo neutrons are expected to be released without a major distortion due to the reaction. The widths of the halo-neutron momentum distributions have been extracted in coincidence with He fragments, Gamma = 32 +/- 4 MeV/c, and Li fragments, Gamma = 42 +/- 4 MeV/c for Be-11 and with He fragments, Gamma =42+/-6 MeV/c for Li-11. The Be-11 breakup gives a very low neutron multiplicity of 0.38+/-0.09 which is a manifestation of the shadowing of the neutron in the core-breakup reaction. This value can be understood from a simple theoretical calculation, which also accounts for the observed transverse momentum widths at small angles. (C) 1999 Elsevier Science B.V.
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