| 1. |
|
|
| 2. |
|
|
| 3. |
|
|
| 4. |
|
|
| 5. |
- Jacobsen, Steven J., et al.
(författare)
-
Comparability of the tandem-R andIMx assays for the measurement of serum prostate-specific antigen
- 1994
-
Ingår i: Urology. - 0090-4295. ; 44:4, s. 512-518
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives.: To assess the comparability of the Tandem-R and IMx serumprostate-specific antigen (PSA) assays across levels of the ratio of free-to-total serum PSA found in a community-based population of healthy men. Methods.: Banked serum samples from the baseline component of the Olmsted CountyStudy of Urinary Symptoms and Health Status Among Men were thawed and analyzed using the Tandem-R and IMx PSA assays. Serum levels also were determined for the free, noncomplexed form of PSA, PSA complexed to alpha-1 antichymotrypsin, and total PSA with a research-based immunofluorometric assay. Results.: The results of the Tandem-R and IMx assays were strongly correlated at alllevels of the ratio of free-to-total serum PSA. The Spearman correlation coefficients ranged from 0.87 to 0.98 (all p < 0.001). The relationship between the Tandem-R and IMx assays, however, differed at low levels of free-to-total serum PSA compared with high levels. In the lowest 10th percentile of the ratio of free-to-total serum PSA (0.04 to 0.18), the IMx assay read lower than the Tandem-R (slope ± standard error = 0.92±0.04, intercept ± standard error = 0.21 ± 0.14); whereas in the upper 10th percentile of free-to-total ratio (0.46 to 0.65) the IMx assay yielded values higher than the Tandem-R assay (slope = 1.21 ± 0.07, intercept = 0.14 ± 0.05). In the middle 90%, the slope did not statistically differ from 1.0. Conclusions.: For the majority of men, results of the Tandem-R and IMx PSA assays were virtually identical. The small differences found would not be of clinical significance for most men but should be considered when comparing results of different assays in sequential determinations for a specific man.
|
|
| 6. |
- Karlsson, BW, et al.
(författare)
-
Patients admitted to the emergency room with symptoms indicative of acute myocardial infarction
- 1991
-
Ingår i: Journal of Internal Medicine. - : Wiley-Blackwell Publishing Ltd.. - 0954-6820 .- 1365-2796. ; 230:3, s. 251-258
-
Tidskriftsartikel (refereegranskat)abstract
- All 7157 patients (55% men) admitted to the emergency room with chest pain or other symptoms indicative of acute myocardial infarction during a period of 21 months were registered consecutively. Chest pain was reported by 93% of the patients. On the basis of history, clinical examination, and electrocardiogram in the emergency room, all patients were prospectively classified in one of four categories: (i) obvious infarction (4% of all patients): (ii) strongly suspected infarction (20%): (iii) vague suspicion of infarction (35%); and (iv) no suspected infarction (41%). In patients with no suspected infarction (n = 2910), musculoskeletal (26%), obscure (21%) and psychogenic origins (16%) of the symptoms occurred most frequently. We conclude that few of the patients had an obvious infarction on admission, and that a musculoskeletal origin of the symptoms occurred most frequently in patients with no suspected infarction.
|
|
| 7. |
|
|
| 8. |
- Åkeby, Hans, et al.
(författare)
-
ELECTRONIC AND GEOMETRIC STRUCTURE OF THE CUN CLUSTER ANIONS (N-LESS-THAN-OR-EQUAL-TO-10)
- 1990
-
Ingår i: Journal of Physical Chemistry. - 0022-3654. ; 94:14, s. 5471-5477
-
Tidskriftsartikel (refereegranskat)abstract
- The structures of the anionic Cu, clusters with n I 10 have been investigated by using correlated wave functions includingthe effects of core (3d)-valence correlation through a model operator. The Cu core orbitals (including 3d) are describedby an effective core potential (ECP). The accuracy of both the ECP description and the treatment of corevalence correlationeffects is established by comparing with all-electron calculations for the smaller clusters. Recent experimental data for theelectron detachment energy (EDE) and HOMO-LUMO separations is combined with the computed total energies to establishthe structure of the observed Cui clusters. The EDE's are found to be strongly structure dependent, which is used to determinewhich of the low-lying structures is observed experimentally.
|
|
