| 1. |
- Friberg, Britt, et al.
(författare)
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Endometrial destruction by thermal coagulation : Evaluation of a new form of treatment for menorrhagia
- 1998
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Ingår i: Gynaecological Endoscopy. - : Wiley. - 0962-1091 .- 1365-2508. ; 7:2, s. 73-78
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Tidskriftsartikel (refereegranskat)abstract
- Objective. To report the first clinical evaluation of a new balloon endometrial, thermal destruction system Cavaterm®, for outpatient treatment of menorrhagia. Design. To elucidate possible technical problems during treatment, to evaluate how the patients tolerated the treatment and to judge which patients were suitable for this form of treatment. Main outcome measures. Measurements of bleeding volumes in pads and tampons before and after treatment were performed as well as subjective evaluation by bleeding charts. Patients also estimated their degree of satisfaction. Setting. Gynaecology department at a university hospital. Subjects. 36 patients under 52 pears of age with menorrhagia, without suspicion of intracavitary pathology including malignancy. Results. No procedure-related complications occurred. The patients tolerated the treatment well. There was a significant reduction in measured bleeding volumes in pads and tampons, collected during one menstruation, 2-7 months after treatment compared with measurements before treatment. Four patients subsequently underwent hysterectomy and should not have been included in the study (two with pedunculated myoma and one with a septum; the fourth showed premalignant endometrial changes in the curettage preceding the treatment). At 18-28-month follow up, 29 of the suitable patients (91%) reported a significant reduction in bleeding and another three patients reported reduced but still profuse bleeding compared with pretreatment; 88% (28/32) rated the treatment results as excellent, and a further 9% (3/32) as good. Conclusions. We found the Cavaterm® system for endometrial destruction to be safe, efficient and easy to use.
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| 2. |
- Jansson, Tomas, et al.
(författare)
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Ultrasound Doppler Vector Tomography - Measurements of Directional Blood Flow
- 1997
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Ingår i: Ultrasound in Medicine and Biology. - 0301-5629. ; 23:1, s. 47-57
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Tidskriftsartikel (refereegranskat)abstract
- An experimental system has been developed to verify the possibility of detecting flow activity using a technique called ultrasound Doppler vector tomography. A tomography algorithm is used to reconstruct blood flow vector fields using data from computer-controlled ultrasound continuous-wave Doppler scanning equipment. The result is a picture in which the brightness variations represent the reconstructed values of the curl of the velocity field (del x v). Continuous ultrasound is transmitted into a region with flow activity and the Doppler-shifted signals are received. To obtain measurement data suited for fan beam tomography, the scanning is performed in a plane from points encircling the region. Reconstructions have been achieved using measurement data from two different flow phantoms. A comparison between the experimental results and simulations shows good conformity. Copyright (C) 1997 World Federation for Ultrasound in Medicine & Biology.
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| 3. |
- Launois, Pascale, et al.
(författare)
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Pressure polymerized C60 single crystals: First x-ray diffraction results
- 1998
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Ingår i: Molecular Nanostructures. - Singapore : World Scientific. - 9789810232610 ; , s. 348-352
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Konferensbidrag (refereegranskat)abstract
- C60 single crystals compressed at approx. 1 GPa and heated at about 300 C are found to polymerize in one dimension without losing their crystalline order. The resulting structure is orthrhombic, with space group Pmnn and parameters a=9.14 Å, b=9.9 Å and c=14.66 Å. The X-ray single crystal results allow us to derive a polymerization mechanism, which may also, for instance, apply to one dimensional C60 polymers in the doped compounds. The new polymer phase is discussed with respect to the C60 pressure-temperature diagram. The comparison with the A1C60 polymers raises questions about the interchain and the alkali metal - fullerene interactins.
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| 4. |
- Löfberg, Robert, et al.
(författare)
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Oral budesonide versus prednisolone in patients with extensive and left sided ulcerative colitis
- 1996
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Ingår i: Gastroenterology. - : Elsevier BV. - 1528-0012 .- 0016-5085. ; 110:6, s. 1713-1718
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND & AIMS: Systemic glucocorticosteroids (GCSs) have proven efficacy in active ulcerative colitis but cause undesired systemic side effects. Therefore, new GCSs with high topical activity and a high rate of metabolism may be of clinical value in this condition. The aim of this study was to explore the efficacy and safety of the topically acting GCS budesonide in an oral controlled-release formulation in extensive or left-sided, mild to moderately active ulcerative colitis. METHODS: A 9-week, randomized, double-blind, controlled trial was performed, and treatments with 10 mg budesonide or 40 mg prednisolone daily, both gradually tapered, were compared. Endoscopic improvement and effect on endogenous plasma cortisol were assessed. RESULTS: Thirty-four patients were administered budesonide, and 38 patients were administered prednisolone. Mean endoscopic scores improved significantly in both groups but without difference between the groups. Five patients in the budesonide group and 7 patients in the prednisolone group deteriorated and were withdrawn from the study. Morning plasma cortisol levels were suppressed in the prednisolone group (entry, 449 nmol/L; 2 weeks, 116 nmol/L; 4 weeks, 195 nmol/L) but were unchanged in the budesonide group. CONCLUSIONS: The GCS budesonide administered in an oral controlled-release formulation seems to give an overall treatment result in active ulcerative colitis approaching that of prednisolone but without suppression of plasma cortisol levels. This concept merits further evaluation.
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| 5. |
- Moret, Roger, et al.
(författare)
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First X-ray diffraction analysis of pressure polymerized C60 single crystals
- 1997
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Ingår i: Europhysics letters. - : IOP Publishing. - 0295-5075 .- 1286-4854. ; 40:1, s. 55-60
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Tidskriftsartikel (refereegranskat)abstract
- It is shown that C60 single crystals can be polymerized under relatively modest pressure-temperature conditions. The resulting single crystals exhibit long-range order and they are made up of 12 orientation variants. The structure is orthorhombic with a short intermolecular distance along the chains (9.14 Å), characteristic of covalent bonding. We propose a structural mechanism for the polymerization of fullerene-based compounds; it involves a shift of one of the (111) cubic planes together with a shortening of the (111) spacing. The configuration of the polymer chains presents interesting relations with that found in the A1C60 polymer compounds.
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| 6. |
- Olsson, Roger, et al.
(författare)
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Organotitanium-induced stereoselective alkylative endo-cleavage of benzyl pentopyranosides
- 1998
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Ingår i: Carbohydrate Research. - 0008-6215. ; 307:1-2, s. 13-18
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Tidskriftsartikel (refereegranskat)abstract
- The results presented are the first examples where organotitanium reagents induced alkylative endo-cleavage of carbohydrates. The best conditions for the alkylative transfer of a methyl group to benzyl 2-deoxy- 2-C-methyl-4-O-(tert-butyldimethylsilyl)-α-D-arabinopyranoside (1) were the application of one equivalent of AlMe3 followed by four equivalents of MeTiCl3 generated by mixing TiCl4 and ZnMe2 in a ratio 2:1, or, alternatively, treatment of I with two equivalents of 1:1 Me2TiCl2-ZnMe2. Both the yields and diastereoselectivities were comparable with those of the reaction with AlMe3 but the titanium reagents were more reactive and could be applied at much lower temperatures than the aluminium reagent.
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| 7. |
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| 8. |
- Persson Österman, Roger
(författare)
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Kontinuitetsprincipen i den svenska inkomstbeskattningen
- 1997
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This dissertation deals with the principle of basis carry-over. The principle of basis carry-over makes possible generation succession and company reorganisations without the accompanying transfers and transactions resulting in taxation for the appreciation of the assets. The basis carry-over means that tax liability is transferred to another tax subject. This occurs because the transferee assumes the transferor’s basis. Thus, taxation is deferred. The transferee is taxed for the entire appreciation upon disposal of the asset. In Sweden, the theoretical foundation for the principle of basis carry-over is unclear. I show that the reason for the application of the principle is the superior goal of achieving effective taxation. This means that a transaction’s capacity to bear tax (i.e. the transaction’s tax elasticity) should have significance for the possibility of using the principle of basis carry-over. Transactions and transfers that occur despite taxation should not be encompassed by the principle of basis carry-over. The problem with the principle of basis carry-over is that the tax subject is changed. This change may be abused. The transferee’s tax situation may result in the assessment of less tax than if the transferor had disposed of the assets in question. It is therefore necessary to precisely regulate the forms for how the principle of basis-carry over may be applied in both generation succession situations and reorganisations. There are other techniques for achieving the same result. One technique is where income for a transfer is calculated but the taxation is deferred (i.e. by allocation to an unrealized intercompany profit account). This prevents exploitation of the transferee’s tax situation in order to reduce tax. It would be desirable therefore if this alternative could be used more frequently in Swedish law. An in-depth analysis of the Swedish legal rules in this area is presented in this dissertation. Generation succession, company formation and other types of reorganisations are scrutinized. The legal rules have developed over a long period of time. The rules are therefore fragmented and different solutions exist for basically the same problems. It is proposed in the dissertation that uniform and concise rules be introduced. This should occur through special legislation.
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| 9. |
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| 10. |
- Sundqvist, Bertil, et al.
(författare)
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Physical properties of pressure polymerized C60
- 1996
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Ingår i: Fullerenes: Recent Advances in the Chemistry and Physics of Fullerenes and Related Materials, volume 3. - Pennington, NJ : The Electrochemical Society. - 1566771625 ; , s. 1014-1028
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Konferensbidrag (refereegranskat)abstract
- We present in this paper an overview of the physical properties of the high pressure polymerized C60 phase commonly known as "soft fcc". This phase has been studied by several methods over wide ranges in temperature T and/or pressure, p. We present here experimental information about the specific heat capacity, the thermal expansion coefficient, the lattice structure, and the thermal conductivity, and we also show results obtained by NMR and Raman spectroscopy. All data presented agree with the accepted model that the individual molecules in this phase are covalently bound to form linear molecular chains. In particular, the NMR data show clearly the presence of covalent bonds, and the Raman data exhibit several new lines at very low energies connected with chain vibrations. Thermal conductivity data obtained during polymerization show both the time dependence of the process and that polymerization occurs at lower p and T than observed previously for this phase.
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| 11. |
- Sundqvist, Bertil, et al.
(författare)
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Structural and physical properties of pressure polymerized C60
- 1998
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Ingår i: Carbon, vol. 36 issue 5-6. - : Elsevier B.V.. ; 36:5-6, s. 657-660
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Konferensbidrag (refereegranskat)abstract
- We discuss the structural and dynamic properties of C60 polymerized under low-P, low-T conditions, and suggest that the disordered mixed orthorhombic-tetragonal-rhombohedral phases produced under these conditions arise from nucleation of molecular chains in random directions because of the quasi-free molecular rotation under standard reaction conditions in the fcc phase of C60. Polymerization in He gives results qualitatively different from those obtained in other media.
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