| 1. |
- Carninci, P, et al.
(författare)
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The transcriptional landscape of the mammalian genome
- 2005
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Ingår i: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 309:5740, s. 1559-1563
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Tidskriftsartikel (refereegranskat)abstract
- This study describes comprehensive polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome. We identify the 5′ and 3′ boundaries of 181,047 transcripts with extensive variation in transcripts arising from alternative promoter usage, splicing, and polyadenylation. There are 16,247 new mouse protein-coding transcripts, including 5154 encoding previously unidentified proteins. Genomic mapping of the transcriptome reveals transcriptional forests, with overlapping transcription on both strands, separated by deserts in which few transcripts are observed. The data provide a comprehensive platform for the comparative analysis of mammalian transcriptional regulation in differentiation and development.
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| 2. |
- Grisolia, C., et al.
(författare)
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JET contributions to ITER technology issues
- 2006
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Ingår i: Fusion engineering and design. - : Elsevier BV. - 0920-3796 .- 1873-7196. ; 81:07-jan, s. 149-154
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Tidskriftsartikel (refereegranskat)abstract
- The Joint European Torus (JET) fusion machine is the only device capable of operation with tritium and of handling Be and therefore is best suited to the study of tritium and fusion-related issues. A large variety of activities are performed within the JET fusion technology task force (FT-TF). In this paper, some topics such as erosion/deposition and material transport, characterisation of flakes and detritiation techniques are highlighted. Recent examples of results obtained on waste management studies are also given. Data on some ITER-relevant components that have been tested at JET, such as a pumping cryopanel and hardened optics fibers, are presented. In all fields, the work to be addressed in future JET work programmes is discussed.
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| 3. |
- Rosanvallon, S., et al.
(författare)
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Tritium related studies within the JET Fusion Technology work programme
- 2005
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Ingår i: Fusion science and technology. - 1536-1055 .- 1943-7641. ; 48:1, s. 268-273
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Tidskriftsartikel (refereegranskat)abstract
- The JET Fusion Technology (FT) work programme was launched in 2000, in the frame of the European Fusion Development Agreement, to address issues related to JET and ITER. In particular, there are four topics related to tritium being investigated Based on the experience gained on the existing tokamaks, first calculations indicate that in-vessel tritium retention could represent a burden for ITER operation. Therefore erosion/deposition studies are being performed in order to better understand the layer co-deposition and tritium retention processes in tokamaks. Moreover, testing of in-situ detritiation processes, in particular laser and flash lamp treatments, should assess detritiation techniques for in-vessel components in the ITER-relevant JET configuration. To reduce the constraints on waste disposal, dedicated procedures are being developed for detritiation Of metals, graphite, carbon-fibre composites, process and housekeeping waste. During the operational and decommissioning phases of a fusion reactor, many processes will produce tritiated water. Key components for an ITER relevant water detritiation facility are being studied experimentally with the aim of producing a complete design that could be implemented and tested at JET. This paper describes these topics of the FT-programme, the strategy developed and the results obtained so far.
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