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1.
  • Aad, G, et al. (författare)
  • 2015
  • swepub:Mat__t
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2.
  • Cossarizza, A., et al. (författare)
  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
  • 2019
  • Ingår i: European Journal of Immunology. - : Wiley. - 0014-2980 .- 1521-4141. ; 49:10, s. 1457-1973
  • Tidskriftsartikel (refereegranskat)abstract
    • These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in murine and human cells. The latest flow cytometry techniques and applications are also described, featuring examples of the data that can be generated and, importantly, how the data can be analysed. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid, all written and peer-reviewed by leading experts in the field, making this an essential research companion.
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3.
  • Hibar, Derrek P., et al. (författare)
  • Novel genetic loci associated with hippocampal volume
  • 2017
  • Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 8
  • Tidskriftsartikel (refereegranskat)abstract
    • The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (r(g) = -0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness.
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4.
  • Lawrenson, Kate, et al. (författare)
  • Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus
  • 2016
  • Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 7
  • Tidskriftsartikel (refereegranskat)abstract
    • A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P=9.2 × 10-20), ER-negative BC (P=1.1 × 10-13), BRCA1-associated BC (P=7.7 × 10-16) and triple negative BC (P-diff=2 × 10-5). Genotype-gene expression associations are identified for candidate target genes ANKLE1 (P=2 × 10-3) and ABHD8 (P<2 × 10-3). Chromosome conformation capture identifies interactions between four candidate SNPs and ABHD8, and luciferase assays indicate six risk alleles increased transactivation of the ADHD8 promoter. Targeted deletion of a region containing risk SNP rs56069439 in a putative enhancer induces ANKLE1 downregulation; and mRNA stability assays indicate functional effects for an ANKLE1 3′-UTR SNP. Altogether, these data suggest that multiple SNPs at 19p13 regulate ABHD8 and perhaps ANKLE1 expression, and indicate common mechanisms underlying breast and ovarian cancer risk.
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5.
  • Reifarth, R., et al. (författare)
  • Nuclear astrophysics with radioactive ions at FAIR
  • 2016
  • Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 665:1
  • Konferensbidrag (refereegranskat)abstract
    • The nucleosynthesis of elements beyond iron is dominated by neutron captures in the s and r processes. However, 32 stable, proton-rich isotopes cannot be formed during those processes, because they are shielded from the s-process flow and r-process beta-decay chains. These nuclei are attributed to the p and rp process. For all those processes, current research in nuclear astrophysics addresses the need for more precise reaction data involving radioactive isotopes. Depending on the particular reaction, direct or inverse kinematics, forward or time-reversed direction are investigated to determine or at least to constrain the desired reaction cross sections. The Facility for Antiproton and Ion Research (FAIR) will offer unique, unprecedented opportunities to investigate many of the important reactions. The high yield of radioactive isotopes, even far away from the valley of stability, allows the investigation of isotopes involved in processes as exotic as the r or rp processes.
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6.
  • Akiba, K., et al. (författare)
  • LHC forward physics
  • 2016
  • Ingår i: Journal of Physics G: Nuclear and Particle Physics. - : IOP Publishing. - 0954-3899 .- 1361-6471. ; 43:11
  • Tidskriftsartikel (refereegranskat)
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7.
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8.
  • Satizabal, Claudia L., et al. (författare)
  • Genetic architecture of subcortical brain structures in 38,851 individuals
  • 2019
  • Ingår i: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 51:11, s. 1624-
  • Tidskriftsartikel (refereegranskat)abstract
    • Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen and thalamus, using genome-wide association analyses in almost 40,000 individuals from CHARGE, ENIGMA and UK Biobank. We show that variability in subcortical volumes is heritable, and identify 48 significantly associated loci (40 novel at the time of analysis). Annotation of these loci by utilizing gene expression, methylation and neuropathological data identified 199 genes putatively implicated in neurodevelopment, synaptic signaling, axonal transport, apoptosis, inflammation/infection and susceptibility to neurological disorders. This set of genes is significantly enriched for Drosophila orthologs associated with neurodevelopmental phenotypes, suggesting evolutionarily conserved mechanisms. Our findings uncover novel biology and potential drug targets underlying brain development and disease.
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11.
  • Atar, L., et al. (författare)
  • Quasifree (p, 2p) Reactions on Oxygen Isotopes: Observation of Isospin Independence of the Reduced Single-Particle Strength
  • 2018
  • Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 120:5
  • Tidskriftsartikel (refereegranskat)abstract
    • Quasifree one-proton knockout reactions have been employed in inverse kinematics for a systematic study of the structure of stable and exotic oxygen isotopes at the R3B/LAND setup with incident beam energies in the range of 300-450 MeV/u. The oxygen isotopic chain offers a large variation of separation energies that allows for a quantitative understanding of single-particle strength with changing isospin asymmetry. Quasifree knockout reactions provide a complementary approach to intermediate-energy one-nucleon removal reactions. Inclusive cross sections for quasifree knockout reactions of the type OA(p,2p)NA-1 have been determined and compared to calculations based on the eikonal reaction theory. The reduction factors for the single-particle strength with respect to the independent-particle model were obtained and compared to state-of-the-art ab initio predictions. The results do not show any significant dependence on proton-neutron asymmetry.
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12.
  • de Zwarte, Sonja M. C., et al. (författare)
  • The association between familial risk and brain abnormalities is disease specific : an ENIGMA-relatives study of schizophrenia and bipolar disorder
  • 2019
  • Ingår i: Biological Psychiatry. - : Elsevier. - 0006-3223 .- 1873-2402. ; 86:7, s. 545-556
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Schizophrenia and bipolar disorder share genetic liability, and some structural brain abnormalities are common to both conditions. First-degree relatives of patients with schizophrenia (FDRs-SZ) show similar brain abnormalities to patients, albeit with smaller effect sizes. Imaging findings in first-degree relatives of patients with bipolar disorder (FDRs-BD) have been inconsistent in the past, but recent studies report regionally greater volumes compared with control subjects.METHODS: We performed a meta-analysis of global and subcortical brain measures of 6008 individuals (1228 FDRs-SZ, 852 FDRs-BD, 2246 control subjects, 1016 patients with schizophrenia, 666 patients with bipolar disorder) from 34 schizophrenia and/or bipolar disorder family cohorts with standardized methods. Analyses were repeated with a correction for intracranial volume (ICV) and for the presence of any psychopathology in the relatives and control subjects.RESULTS: FDRs-BD had significantly larger ICV (d = +0.16, q < .05 corrected), whereas FDRs-SZ showed smaller thalamic volumes than control subjects (d = -0.12, q < .05 corrected). ICV explained the enlargements in the brain measures in FDRs-BD. In FDRs-SZ, after correction for ICV, total brain, cortical gray matter, cerebral white matter, cerebellar gray and white matter, and thalamus volumes were significantly smaller; the cortex was thinner (d < -0.09, q < .05 corrected); and third ventricle was larger (d = +0.15, q < .05 corrected). The findings were not explained by psychopathology in the relatives or control subjects.CONCLUSIONS: Despite shared genetic liability, FDRs-SZ and FDRs-BD show a differential pattern of structural brain abnormalities, specifically a divergent effect in ICV. This may imply that the neurodevelopmental trajectories leading to brain anomalies in schizophrenia or bipolar disorder are distinct.
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14.
  • Diaz Fernandez, Paloma, 1983, et al. (författare)
  • Quasifree (p, pN) scattering of light neutron-rich nuclei near N=14
  • 2018
  • Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 97:2
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: For many years, quasifree scattering reactions in direct kinematics have been extensively used to study the structure of stable nuclei, demonstrating the potential of this approach. The (RB)-B-3 collaboration has performed a pilot experiment to study quasifree scattering reactions in inverse kinematics for a stable C-12 beam. The results from that experiment constitute the first quasifree scattering results in inverse and complete kinematics. This technique has lately been extended to exotic beams to investigate the evolution of shell structure, which has attracted much interest due to changes in shell structure if the number of protons or neutrons is varied. Purpose: In this work we investigate for the first time the quasifree scattering reactions (p, pn) and (p, 2p) simultaneously for the same projectile in inverse and complete kinematics for radioactive beams with the aim to study the evolution of single-particle properties from N = 14 to N = 15. Method: The structure of the projectiles O-23, O-22, and N-21 has been studied simultaneously via (p, pn) and (p, 2p) quasifree knockout reactions in complete inverse kinematics, allowing the investigation of proton and neutron structure at the same time. The experimental data were collected at the (RB)-B-3-LAND setup at GSI at beam energies of around 400 MeV/u. Two key observables have been studied to shed light on the structure of those nuclei: the inclusive cross sections and the corresponding momentum distributions. Conclusions: The knockout reactions (p, pn) and (p, 2p) with radioactive beams in inverse kinematics have provided important and complementary information for the study of shell evolution and structure. For the (p, pn) channels, indications of a change in the structure of these nuclei moving from N = 14 to N = 15 have been observed, i.e., from the 0d(5/2) shell to the 1s(1/2). This supports previous observations of a subshell closure at N = 14 for neutron-rich oxygen isotopes and its weakening for the nitrogen isotopes.
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16.
  • Paradela, C., et al. (författare)
  • High accuracy 235U(n,f) data in the resonance energy region
  • 2016
  • Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 2100-014X.
  • Konferensbidrag (refereegranskat)abstract
    • The U-235 neutron-induced cross section is widely used as reference cross section for measuring other fission cross sections, but in the resonance region it is not considered as an IAEA standard because of the scarce experimental data covering the full region. In this work, we deal with a new analysis of the experimental data obtained with a detection setup based on parallel plate ionization chambers (PPACs) at the CERN n_TOF facility in the range from 1 eV to 10 keV. The relative cross section has been normalised to the IAEA value in the region between 7.8 and 11 eV, which is claimed as well-known. Comparison with the ENDF/B-VII evaluation and the IAEA reference file from 100 eV to 10 keV are provided.
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17.
  • Revel, A., et al. (författare)
  • Strong Neutron Pairing in core+4n Nuclei
  • 2018
  • Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 120:15
  • Tidskriftsartikel (refereegranskat)abstract
    • The emission of neutron pairs from the neutron-rich N=12 isotones C18 and O20 has been studied by high-energy nucleon knockout from N19 and O21 secondary beams, populating unbound states of the two isotones up to 15 MeV above their two-neutron emission thresholds. The analysis of triple fragment-n-n correlations shows that the decay N19(-1p)C18∗→C16+n+n is clearly dominated by direct pair emission. The two-neutron correlation strength, the largest ever observed, suggests the predominance of a C14 core surrounded by four valence neutrons arranged in strongly correlated pairs. On the other hand, a significant competition of a sequential branch is found in the decay O21(-1n)O20∗→O18+n+n, attributed to its formation through the knockout of a deeply bound neutron that breaks the O16 core and reduces the number of pairs.
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18.
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19.
  • Vandebrouck, M., et al. (författare)
  • Effective proton-neutron interaction near the drip line from unbound states in F-25,F-26
  • 2017
  • Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 96:5
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Odd-odd nuclei, around doubly closed shells, have been extensively used to study proton-neutron interactions. However, the evolution of these interactions as a function of the binding energy, ultimately when nuclei become unbound, is poorly known. The F-26 nucleus, composed of a deeply bound pi 0d(5/2) proton and an unbound v0d(3/2) neutron on top of an O-24 core, is particularly adapted for this purpose. The coupling of this proton and neutron results in a J(pi) = 1(1)(+) - 4(1)(+) multiplet, whose energies must be determined to study the influence of the proximity of the continuum on the corresponding proton-neutron interaction. The J(pi) = 1(1)(+), 2(1)(+), 4(1)(+) bound states have been determined, and only a clear identification of the J(pi) = 3(1)(+) is missing. Purpose: We wish to complete the study of the J(pi) = 1(1)(+) - 4(1)(+) multiplet in F-26, by studying the energy and width of the J(pi) = 3(1)(+) unbound state. The method was first validated by the study of unbound states in F-25, for which resonances were already observed in a previous experiment. Method: Radioactive beams of Ne-26 and Ne-27, produced at about 440AMeV by the fragment separator at the GSI facility were used to populate unbound states in F-25 and F-26 via one-proton knockout reactions on a CH2 target, located at the object focal point of the (RB)-B-3/LAND setup. The detection of emitted. rays and neutrons, added to the reconstruction of the momentum vector of the A - 1 nuclei, allowed the determination of the energy of three unbound states in F-25 and two in F-26. Results: Based on its width and decay properties, the first unbound state in F-25, at the relative energy of 49(9) keV, is proposed to be a J(pi) = 1/ 2(-) arising from a p1/2 proton- hole state. In F-26, the first resonance at 323(33) keV is proposed to be the J(pi) = 3(1)(+) member of the J(pi) = 1(1)(+) - 4(1)(+) multiplet. Energies of observed states in F-25,F-26 have been compared to calculations using the independent-particle shell model, a phenomenological shell model, and the ab initio valence-space in-medium similarity renormalization group method. Conclusions: The deduced effective proton- neutron interaction is weakened by about 30-40% in comparison to the models, pointing to the need for implementing the role of the continuum in theoretical descriptions or to a wrong determination of the atomic mass of F-26.
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20.
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21.
  • Holl, M., et al. (författare)
  • Quasi-free neutron and proton knockout reactions from light nuclei in a wide neutron-to-proton asymmetry range
  • 2019
  • Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 795, s. 682-688
  • Tidskriftsartikel (refereegranskat)abstract
    • The quasi-free scattering reactions 11C(p,2p) and 10,11,12C(p,pn) have been studied in inverse kinematics at beam energies of 300–400 MeV/u at the R3B-LAND setup. The outgoing proton-proton and proton-neutron pairs were detected in coincidence with the reaction fragments in kinematically complete measurements. The efficiency to detect these pairs has been obtained from GEANT4 simulations which were tested using the 12C(p,2p) and 12C(p,pn) reactions. Experimental cross sections and momentum distributions have been obtained and compared to DWIA calculations based on eikonal theory. The new results reported here are combined with previously published cross sections for quasi-free scattering from oxygen and nitrogen isotopes and together they enable a systematic study of the reduction of single-particle strength compared to predictions of the shell model over a wide neutron-to-proton asymmetry range. The combined reduction factors show a weak or no dependence on isospin asymmetry, in contrast to the strong dependency reported in nucleon-removal reactions induced by nuclear targets at lower energies. However, the reduction factors for (p,2p) are found to be 'significantly smaller than for (p,pn) reactions for all investigated nuclei.
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22.
  • Ribeiro, G., et al. (författare)
  • Structure of Be-13 studied in proton knockout from B-14
  • 2018
  • Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 98:2
  • Tidskriftsartikel (refereegranskat)abstract
    • The neutron-unbound isotope Be-13 has been studied in several experiments using different reactions, different projectile energies, and different experimental setups. There is, however, no real consensus in the interpretation of the data, in particular concerning the structure of the low-lying excited states. Gathering new experimental information, which may reveal the Be-13 structure, is a challenge, particularly in light of its bridging role between Be-12, where the N = 8 neutron shell breaks down, and the Borromean halo nucleus Be-14. The purpose of the present study is to investigate the role of bound excited states in the reaction product Be-12 after proton knockout from B-14, by measuring coincidences between Be-12, neutrons, and gamma rays originating from de-excitation of states fed by neutron decay of Be-13. The Be-13 isotopes were produced in proton knockout from a 400 MeV/nucleon B-14 beam impinging on a CH2 target. The Be-12-n relative-energy spectrum d sigma/dE(fn) was obtained from coincidences between Be-12(g.s.) and a neutron, and also as threefold coincidences by adding gamma rays, from the de-excitation of excited states in Be-12. Neutron decay from the first 5/2(+) state in Be-13 to the 2(+) state in Be-12 at 2.11 MeV is confirmed. An energy independence of the proton-knockout mechanism is found from a comparison with data taken with a 35 MeV/nucleon B-14 beam. A low-lying p-wave resonance in Be-13(1/2(-)) is confirmed by comparing proton- and neutron-knockout data from B-14 and Be-14.
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23.
  • Benlliure, J., et al. (författare)
  • New experimental approaches to investigate the fission dynamics
  • 2016
  • Ingår i: AIP Conference Proceedings. - : Author(s). - 1551-7616 .- 0094-243X. - 9780735414112 ; 1753
  • Konferensbidrag (refereegranskat)abstract
    • The first ever achieved full identification of both fission fragments, in atomic and mass number, made it possible to define new observables sensitive to the fission dynamics along the fission path up to the scission point. Moreover, proton-induced fission of 208Pb at high energies offers optimal conditions for the investigation of dissipative, and transient effects, because of the high-excitation energy of the fissioning nuclei, its low angular momentum, and limited shape distortion by the reaction. In this work we show that the charge distribution of the final fission fragments can constrain the ground-to-saddle dynamics while the mass distribution is sensitive to the dynamics until the scission point.
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24.
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25.
  • Chatillon, A., et al. (författare)
  • Accurate measurements of fission-fragment yields in U-234,U-235,U-236,U-238(gamma,f) with the SOFIA set-up
  • 2016
  • Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 2101-6275 .- 2100-014X. - 9782759819706 ; 111
  • Konferensbidrag (refereegranskat)abstract
    • SOFIA (Studies On Fission with Aladin) is a new experimental set-up dedicated to accurate measurement of fission-fragments isotopic yields. It is located at GSI, the only place to use inverse kinematics at relativistic energies in order to study the (gamma,f) electromagnetic-induced fission. The SOFIA set-up is a large-acceptance magnetic spectrometer, which allows to fully identify both fission fragments in coincidence on the whole fission-fragment range. This paper will report on fission yields obtained in U-234,U-235,U-236,U-238(gamma,f) reactions.
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26.
  • Chatillon, A., et al. (författare)
  • Experimental study of nuclear fission along the thorium isotopic chain: From asymmetric to symmetric fission
  • 2019
  • Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 99:5
  • Tidskriftsartikel (refereegranskat)abstract
    • The inverse kinematics technique, applied to radioactive beams and combined to the Coulomb excitation method, is a powerful tool to study low-energy fission. A novel experimental setup was developed within the R3B/SOFIA (Reactions with Relativistic Radioactive Beams/Studies On FIssion with Aladin) collaboration to identify in mass and atomic numbers both fission fragments in coincidence. These new data provide elemental, isobaric, and isotonic yields for the fission along the thorium isotopic chain. Results are also compared to previous measurements using either the same reaction mechanism or thermal-neutron induced fission. This latter comparison permits to probe the influence of the excitation energy in the fission process.
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27.
  • Gorbinet, T., et al. (författare)
  • A sample of the results of the first SOFIA experiment
  • 2015
  • Ingår i: Physics Procedia. - : Elsevier BV. - 1875-3884 .- 1875-3892. ; 64, s. 101-106
  • Konferensbidrag (refereegranskat)abstract
    • The first SOFIA experiment (Studies On FIssion with Aladin) was performed in August 2012 at GSI. The fission of several neutron-deficient actinides and pre-actinides was induced in flight at 700 A MeV by electromagnetic excitation. The use of inverse kinematics provides both high detection and high geometrical efficiency. The complete identification of both fission fragments in coincidence (nuclear charge and mass) was obtained over a broad range of fissioning nuclei. After a short introduction and description of the experimental setup, the quality of the charge and mass separation is presented, followed by some results concerning the Coulex-induced fission of U-234 and U-235. (C) 2015 Published by Elsevier B.V.
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28.
  • Grente, L., et al. (författare)
  • The SOFIA experiment: Measurement of 236U fission fragment yields in inverse kinematics
  • 2016
  • Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 2101-6275 .- 2100-014X. ; 122:01006
  • Konferensbidrag (refereegranskat)abstract
    • The SOFIA (Studies On FIssion with Aladin) experiment aims at measuring fission-fragments isotopic yields with high accuracy using inverse kinematics at relativistic energies. This experimental technique allows to fully identify the fission fragments in nuclear charge and mass number, thus providing very accurate isotopic yields for low energy fission of a large variety of fissioning systems. This report focuses on the latest results obtained with this set-up concerning electromagnetic-induced fission of 236U.
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29.
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30.
  • Heine, M., et al. (författare)
  • Determination of the neutron-capture rate of C-17 for r-process nucleosynthesis
  • 2017
  • Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 95:1, s. Article no 014613 -
  • Tidskriftsartikel (refereegranskat)abstract
    • With the (RB)-B-3-LAND setup at GSI we have measured exclusive relative-energy spectra of the Coulomb dissociation of C-18 at a projectile energy around 425A MeV on a lead target, which are needed to determine the radiative neutron-capture cross sections of C-17 into the ground state of C-18. Those data have been used to constrain theoretical calculations for transitions populating excited states in C-18. This allowed to derive the astrophysical cross section sigma(n gamma)*. accounting for the thermal population of C-17 target states in astrophysical scenarios. The experimentally verified capture rate is significantly lower than those of previously obtained Hauser-Feshbach estimations at temperatures T-9
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31.
  • Knyazev, Alexander, et al. (författare)
  • Properties of the CsI(Tl) detector elements of the CALIFA detector
  • 2019
  • Ingår i: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. - : Elsevier BV. - 0168-9002. ; 940, s. 393-404
  • Tidskriftsartikel (refereegranskat)abstract
    • In the R3B experiment at FAIR, charged particles with energies up to 600 MeV and forward boosted γ-rays with energies up to 20 MeV need to be detected in scattering experiments. Calorimeters for nuclear physics experiments of this kind, using relativistic radioactive ion beams, require high energy resolution and high efficiency for simultaneous detection of strongly Doppler shifted γ-rays and high-energy charged particles. A calorimeter design that can meet these requirements, using CsI(Tl) scintillators, results in detector elements that may exhibit light output variations with crystal depth, which can limit the attainable resolution. In this paper we present results from a systematic study of 478 detector modules of CALIFA, the R3B calorimeter, in order to determine and minimize such variations. To facilitate further systematic studies we also present results for the total absorption length of the scintillation light, using spectrophotometry, light crosstalk between adjacent detector modules, and surface topography of the CsI(Tl) crystals from atomic force microscopy.
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32.
  • Mantovani, G., et al. (författare)
  • Study of High-Energy Fission in Inverse Kinematics
  • 2019
  • Ingår i: IV INTERNATIONAL CONFERENCE ON NUCLEAR STRUCTURE AND DYNAMICS (NSD2019). - : EDP Sciences. - 2100-014X. - 9782759890842 ; 223
  • Konferensbidrag (refereegranskat)abstract
    • Fission at low excitation energy, is a process in which both macroscopic and microscopic aspects are involved. Some features in the total kinetic energy and in the N/Z distributions of the fragments, commonly associated with shell effects, came out in a series of recent experiments with high excitation energy fusion fission reactions in inverse kinematics. In the latest experiment of this campaign, a study of high-energy fission and quasi-fission between a U-238 beam and a series of light targets was carried out by using the aforementioned technique, in order to probe the role of the shell structure in these processes.
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33.
  • Martin, J. F., et al. (författare)
  • Studies on fission with ALADIN Precise and simultaneous measurement of fission yields, total kinetic energy and total prompt neutron multiplicity at GSI
  • 2015
  • Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-601X .- 1434-6001. ; 51:12, s. 1-8
  • Tidskriftsartikel (refereegranskat)abstract
    • A novel technique for fission studies, based on the inverse kinematics approach, is presented. Following pioneering work in the nineties, the SOFIA Collaboration has designed and built an experimental set-up dedicated to the simultaneous measurement of isotopic yields, total kinetic energies and total prompt neutron multiplicities, by fully identifying both fission fragments in coincidence, for the very first time. This experiment, performed at GSI, permits to study the fission of a wide variety of fissioning systems, ranging from mercury to neptunium, possibly far from the valley of stability. A first experiment, performed in 2012, has provided a large array of unprecedented data regarding the nuclear fission process. An excerpt of the results is presented. With this solid starter, further improvements of the experimental set-up are considered, which are consistent with the expected developments at the GSI facility, in order to measure more fission observables in coincidence. The completeness reached in the SOFIA data, permits to scrutinize the correlations between the interesting features of fission, offering a very detailed insight in this still unraveled mechanism.
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34.
  • Pellereau, E., et al. (författare)
  • Accurate isotopic fission yields of electromagnetically induced fission of U 238 measured in inverse kinematics at relativistic energies
  • 2017
  • Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993. ; 95:5, s. 054603-
  • Tidskriftsartikel (refereegranskat)abstract
    • SOFIA (Studies On Fission with Aladin) is a novel experimental program, dedicated to accurate measurements of fission-fragment isotopic yields. The setup allows us to fully identify, in nuclear charge and mass, both fission fragments in coincidence for the whole fission-fragment range. It was installed at the GSI facility (Darmstadt), to benefit from the relativistic heavy-ion beams available there, and thus to use inverse kinematics. This paper reports on fission yields obtained in electromagnetically induced fission of U238.
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35.
  • Pietras, B., et al. (författare)
  • First testing of the CALIFA Barrel Demonstrator
  • 2016
  • Ingår i: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. - : Elsevier BV. - 0168-9002. ; 814, s. 56-65
  • Tidskriftsartikel (refereegranskat)abstract
    • Advancement of the CALIFA calorimeter project has reached a new milestone with the construction of the first modules of the CALIFA Demonstrator, ultimately to be integrated into the final calorimeter. Aspects and methods of detector optimisation will be discussed, along with characterisation using proton beams of 70
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36.
  • Rodriguez-Sanchez, J. L., et al. (författare)
  • Complete characterization of the fission fragments produced in reactions induced by Pb 208 projectiles on proton at 500A MeV
  • 2015
  • Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993. ; 91:6
  • Tidskriftsartikel (refereegranskat)abstract
    • The two fragments produced in fission reactions induced by Pb208 projectiles impinging on a liquid hydrogen target at 500AMeV have been fully identified in coincidence. The experiment was performed at GSI Darmstadt, where the combined use of the inverse kinematics technique with an efficient detection setup permitted one to detect and to fully identify the fission fragments in a range from Z=27 to Z=52. The corresponding isotopic cross sections and velocities of the fission fragments were measured with high accuracy. The results are compared to state-of-the-art model calculations that reproduce the measured observables. Correlations between the two fragments were used to assess the role of charge polarization and the excitation energy gained by the nascent fragments using the neutron excess of the final fragments. The analysis of the average velocities of the fission fragments allowed us to parametrize the distance between the two fission fragments at scission as a function of the size of the fissioning system.
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37.
  • Rodriguez-Sanchez, J. L., et al. (författare)
  • Constraining the level density using fission of lead projectiles
  • 2015
  • Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993. ; 92:4
  • Tidskriftsartikel (refereegranskat)abstract
    • The nuclear level density is one of the main ingredients for the statistical description of the fission process. In this work, we propose to constrain the description of this parameter by using fission reactions induced by protons and light ions on Pb208 at high kinetic energies. The experiment was performed at GSI (Darmstadt), where the combined use of the inverse kinematics technique with an efficient detection setup allowed us to measure the atomic number of the two fission fragments in coincidence. This measurement permitted us to obtain with high precision the partial fission cross sections and the width of the charge distribution as a function of the atomic number of the fissioning system. These data and others previously measured, covering a large range in fissility, are compared to state-of-the-art calculations. The results reveal that total and partial fission cross sections cannot unambiguously constrain the level density at ground-state and saddle-point deformations and additional observables, such as the width of the charge distribution of the final fission fragments, are required.
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38.
  • Rodriguez-Sanchez, J. L., et al. (författare)
  • Dissipative effects in fission investigated in complete kinematics measurements
  • 2017
  • Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 2101-6275 .- 2100-014X. - 9782759890200 ; 146
  • Konferensbidrag (refereegranskat)abstract
    • The study of dissipative effects in fission has been carried out with fusion-fission reactions by using a limited number of observables, such as the fission probabilities, the mass distribution of the fission fragments, or the neutron multiplicities. However, the large angular momenta gained by the compound nucleus in this kind of reaction could affect the conclusions drawn from such experiments. In this work, we propose to investigate the fission dynamics by the use of spallation reactions on 208Pb because the fissioning systems are produced with low angular momentum, small deformations, and high excitation energies, enhancing the dissipative effects. The complete kinematics measurements of the fission fragments and light-charged particles were performed by the use of the SOFIA setup combined with the inverse kinematics technique, allowing us for the first time a full indentification in atomic and mass number of the two fission fragments. These measurements permit us to define new fission observables for the investigation of the temperature and deformation dependencies of the dissipation parameter.
  •  
39.
  • Rodriguez-Sanchez, J. L., et al. (författare)
  • Dissipative effects in fission investigated with proton-on-lead reactions
  • 2016
  • Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 2101-6275 .- 2100-014X. - 9788874381012 ; 117, s. Art. no. 08017-
  • Konferensbidrag (refereegranskat)abstract
    • The complete kinematic measurement of the two fission fragments permitted us to investigate dissipative effects at large deformations, between the saddle-point and the corresponding scission configurations. Up to now, this kind of study has only been performed with fusionfission reactions using a limited number of observables, such as the mass distribution of the fission fragments or the neutron multiplicities. However, the large angular momenta gained by the compound nucleus could affect the conclusions drawn from such experiments. In this work, the use of spallation reactions, where the fissioning systems are produced with low angular momentum, small deformations and high excitation energies, favors the study of dissipation, and allowed us to define new observables, such as postscission neutron multiplicities and the neutron excess of the final fission fragments as a function of the atomic number of the fissioning system. These new observables are used to investigate the dissipation at large deformations.
  •  
40.
  • Rodriguez-Sanchez, J. L., et al. (författare)
  • Fission dynamics at high excitation energies investigated in complete kinematics measurements
  • 2017
  • Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 863:1, s. Article no 012047-
  • Konferensbidrag (refereegranskat)abstract
    • Light-charged particles emitted in proton-induced fission reactions on 208 Pb have been measured at different kinetic energies: 370A, 500A, and 650A MeV. The experiment was performed by the SOFIA collaboration at the GSI facilities in Darmstadt (Germany). The inverse kinematics technique was combined with a setup especially designed to measure light-charged particles in coincidence with fission fragments. The data were compared with different model calculations to assess the ground-to-saddle dynamics. The results confirm that transient and dissipative effects are required for an accurate description of the fission observables.
  •  
41.
  • Rodriguez-Sanchez, J. L., et al. (författare)
  • Light charged particles emitted in fission reactions induced by protons on Pb-208
  • 2016
  • Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 94:3
  • Tidskriftsartikel (refereegranskat)abstract
    • Light charged particles emitted in proton-induced fission reactions on Pb-208 have been measured at different kinetic energies: 370A, 500A, and 650A MeV. The experiment was performed by the SOFIA Collaboration at the GSI facilities in Darmstadt (Germany). The inverse kinematics technique was combined with a setup especially designed to measure light charged particles in coincidence with fission fragments. This measurement allowed us, for the first time, to obtain correlations between the light charged particles emitted during the fission process and the charge distributions of the fission fragments. These correlations were compared with different model calculations to assess the ground-to-saddle dynamics. The results confirm that transient and dissipative effects are required for an accurate description of the fission observables.
  •  
42.
  • Rodriguez-Sanchez, J. L., et al. (författare)
  • Presaddle and postsaddle dissipative effects in fission using complete kinematics measurements
  • 2016
  • Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 94:6
  • Tidskriftsartikel (refereegranskat)abstract
    • A complete kinematics measurement of the two fission fragments was used for the first time to investigate fission dynamics at small and large deformations. Fissioning systems with high excitation energies, compact shapes, and low angular momenta were produced in inverse kinematics by using spallation reactions of lead projectiles. A new generation experimental setup allowed for the first full and unambiguous identification in mass and atomic number of both fission fragments. This measurement permitted us to accurately determine fission cross sections, the charge distribution, and the neutron excess of the fission fragments as a function of the atomic number of the fissioning system. These data are compared with different model calculations to extract information on the value of the dissipation parameter at small and large deformations. The present results do not show any sizable dependence of the nuclear dissipation parameter on temperature or deformation.
  •  
43.
  • Rodriguez-Sanchez, J. L., et al. (författare)
  • Transient effects in fission investigated with proton-on-lead reactions in complete kinematic measurements
  • 2015
  • Ingår i: Physics Procedia. - : Elsevier BV. - 1875-3884 .- 1875-3892. ; 64, s. 157-162
  • Konferensbidrag (refereegranskat)abstract
    • Proton-induced fission of Pb-208 has been investigated at 370, 500 and 650 A MeV in complete kinematic measurements. The experiment was performed at GSI Darmstadt where the combined use of the inverse kinematics technique with an efficient detection setup allowed to measure for the first time the atomic and mass number of both fission fragments. The performed measurement together with different model calculations allow us to investigate dissipative and transient effects in the fission process and the dependence on temperature and deformation of the dissipation strength beta. The use of spallation reactions with lead projectiles favours this study due to its high excitation energy and low angular momentum. (C) 2015 The Authors. Published by Elsevier B.V.
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44.
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45.
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46.
  • Röder, M., et al. (författare)
  • Coulomb dissociation of 20,21 N
  • 2016
  • Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993 .- 0556-2813. ; 93:6
  • Tidskriftsartikel (refereegranskat)abstract
    • Neutron-rich light nuclei and their reactions play an important role in the creation of chemical elements. Here, data from a Coulomb dissociation experiment on N20,21 are reported. Relativistic N20,21 ions impinged on a lead target and the Coulomb dissociation cross section was determined in a kinematically complete experiment. Using the detailed balance theorem, the N19(n,γ)N20 and N20(n,γ)N21 excitation functions and thermonuclear reaction rates have been determined. The N19(n,γ)N20 rate is up to a factor of 5 higher at T
  •  
47.
  • Thies, Ronja, 1987, et al. (författare)
  • Systematic investigation of projectile fragmentation using beams of unstable B and C isotopes
  • 2016
  • Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993 .- 0556-2813. ; 93:5
  • Tidskriftsartikel (refereegranskat)abstract
    • Models describing nuclear fragmentation and fragmentation fission deliver important input for planning nuclear physics experiments and future radioactive ion beam facilities. These models are usually benchmarked against data from stable beam experiments. In the future, two-step fragmentation reactions with exotic nuclei as stepping stones are a promising tool for reaching the most neutron-rich nuclei, creating a need for models to describe also these reactions. Purpose: We want to extend the presently available data on fragmentation reactions towards the light exotic region on the nuclear chart. Furthermore, we want to improve the understanding of projectile fragmentation especially for unstable isotopes. Method: We have measured projectile fragments from C10,12-18 and B10-15 isotopes colliding with a carbon target. These measurements were all performed within one experiment, which gives rise to a very consistent data set. We compare our data to model calculations. Results: One-proton removal cross sections with different final neutron numbers (1pxn) for relativistic C10,12-18 and B10-15 isotopes impinging on a carbon target. Comparing model calculations to the data, we find that the epax code is not able to describe the data satisfactorily. Using abrabla07 on the other hand, we find that the average excitation energy per abraded nucleon needs to be decreased from 27 MeV to 8.1 MeV. With that decrease abrabla07 describes the data surprisingly well. Conclusions: Extending the available data towards light unstable nuclei with a consistent set of new data has allowed a systematic investigation of the role of the excitation energy induced in projectile fragmentation. Most striking is the apparent mass dependence of the average excitation energy per abraded nucleon. Nevertheless, this parameter, which has been related to final-state interactions, requires further study.
  •  
48.
  • Audouin, L., et al. (författare)
  • High-precision measurement of isotopic fission yields of 236 U
  • 2018
  • Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 2101-6275 .- 2100-014X. ; 193
  • Konferensbidrag (refereegranskat)abstract
    • We report on the second SOFIA experiment, dedicated to the fission yields of 236U∗, analog to 235U(n,f). The measurement is based on the inverse kinematics method, using a relativistic, secondary beam of 236U. Both fission fragments are identified in mass and charge in the SOFIA recoil spectrometer. The obtained isotopic yields are compared with existing spectroscopy measurements and the elemental yields are used to discuss the treatment of the even-odd effect with energy in nuclear data libraries.
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49.
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