| 1. |
- Lekki, J., et al.
(författare)
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On the follicular pathway of percutaneous uptake of nanoparticles: Ion microscopy and autoradiography studies
- 2007
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Ingår i: Nuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms. - : Elsevier BV. - 0168-583X. ; 260:1, s. 174-177
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Tidskriftsartikel (refereegranskat)abstract
- We report on the visualization of the penetration of sunscreen formulations containing TiO2 nanoparticles (about 20 nm primary particle size) into hair follicles of both human and porcine skin using the complementary methods of ion microscopy (PIXE, RBS, STIM) and autoradiography. Particles were found as deep as approx. 400 pin in the follicle, obviously introduced mechanically rather than by a diffusive process. No particles were observed in vital tissue nor in sebaceous glands. (c) 2007 Elsevier B.V. All rights reserved.
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| 2. |
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| 3. |
- Nilsson, Charlotta, et al.
(författare)
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The new target chamber at LIPSION: The new translation stage and goniometer and the new irradiation platform for single cell experiments
- 2007
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Ingår i: Nuclear Instruments and Methods in Physics Research Section B. - : Elsevier BV. ; 260:1, s. 71-76
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Tidskriftsartikel (refereegranskat)abstract
- A new target chamber as well as a new 7-axes translation stage with goniometer will shortly be implemented at the LIPSION nanoprobe in Leipzig. This new stage should enable linear motion as well as rotary motion with high precision, positioning accuracy and repeatability. These different features have been investigated online as well as offline, with encouraging results. Along with the new equipment, new software is also being developed, to provide stage control running over network. These software developments, including a graphical user interface, will also be described. As part of the new target chamber, a new external beam facility and irradiation platform for single ion experiments on single living cells is being assembled. A detailed description of the new cell irradiation platform, including beam extraction, new cell dishes, and cell recognition aspects will be given. It will be shown that the possibility of offline cell recognition, possibly using a differential interference contrast microscope, is an option.
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| 4. |
- Jacquet, J M, et al.
(författare)
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Safety and immunogenicity of a combined DTPa-IPV vaccine administered as a booster from 4 years of age : a review
- 2006
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Ingår i: Vaccine. - : Elsevier BV. - 0264-410X .- 1873-2518. ; 24:13, s. 2440-2448
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Tidskriftsartikel (refereegranskat)abstract
- A combined DTPa-IPV booster vaccine was administered as a 4th or 5th dose after DTPa or DTPw priming. Over 99% vaccines developed antibody levels considered to be protective to diphtheria, tetanus and poliovirus, and >95% mounted a response to acellular pertussis antigens. Rectal temperature >39.5 degrees C was observed in at most 3.2% of vaccinees. Swelling >50 mm occurred in 24% of DTPa-primed compared to 5.5% of DTPw-primed children. Large swelling involving the entire upper arm (extending to involve the elbow joint) was reported for up to 1.2% of DTPa-primed subjects, which is consistent with literature reports for other DTPa vaccines.
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