| 1. |
- Franke Stenport, Victoria, 1970, et al.
(författare)
-
Failure to induce supracrestal bone growth between and around partially inserted titanium implants using bone morphogenetic protein (BMP): an experimental study in dogs.
- 2003
-
Ingår i: Clinical oral implants research. - : Blackwell Munksgaard. - 0905-7161 .- 1600-0501. ; 14:2, s. 219-25
-
Tidskriftsartikel (refereegranskat)abstract
- The effect of bone morphogenetic protein on supracrestal bone growth around partially inserted implants in a dog model is described. The lower premolar teeth (P1, P2, P3 and P4) were extracted on both sides of the mandible in six dogs. At a surgical exposure 12 weeks later, two 10-mm turned titanium implants were partially inserted, approximately 15 mm apart, in the areas of the P1 and P3 in each side of the mandible, allowing five threads to protrude from the bone crest. A titanium mesh was fastened to the coronal aspect of the two fixtures and the space beneath the mesh was filled with bone morphogenetic protein (S300 BMP) in combination with an insoluble bone matrix carrier, or with the carrier alone. The mesh was covered with an ePTFE membrane. Thus, a space for potential bone formation was created between the two implants. The surgical flaps were coronally positioned and secured with vertical mattress sutures. After 16 weeks of healing, biopsy specimens were retrieved and examined histologically. Bone was not formed around the protruding implants or in the created space between the implants in any case. The carrier was incompletely resorbed. We conclude that supracrestal bone growth beyond the crestal limit with or without BMP in such a large space as in this experimental design may not be possible.
|
|
| 2. |
- Roos-Jansåker, Ann-Marie, et al.
(författare)
-
Dog model for study of supracrestal bone apposition around partially inserted implants.
- 2002
-
Ingår i: Clinical oral implants research. - 0905-7161. ; 13:5, s. 455-9
-
Tidskriftsartikel (refereegranskat)abstract
- A dog model for study of supracrestal bone growth around partially inserted implants is described. The mandibular premolar teeth (P1, P2, P3 and P4) were extracted on both sides of the mandible in four dogs. At a surgical exposure 12 weeks later, two 10 mm titanium implants were partially inserted on each side, 15 mm apart, in the areas of the P1 and the P3 so that five threads protruded from the bone crest. A titanium mesh was fastened to the coronal aspect of the two fixtures and covered with an ePTFE membrane. Thus, a space for potential bone formation was created between the two implants. The surgical flaps were coronally positioned and secured with vertical mattress sutures. After 12 weeks of healing, biopsy specimens were retrieved and examined histologically. In three of the four dogs under study, the partially inserted implants had integrated and the intended large wound spaces had been created around the noninserted parts of the implants. However, bone was not formed around the protruding implants. Accordingly, this experimental model may prove useful for future studies on the use of various procedures that hypothetically may enhance bone formation.
|
|
| 3. |
- Roos-Jansåker, Ann-Marie, et al.
(författare)
-
Treatment of peri-implant infections : a literature review
- 2003
-
Ingår i: Journal of Clinical Periodontology. - 0303-6979 .- 1600-051X. ; 30:6, s. 467-485
-
Forskningsöversikt (refereegranskat)abstract
- Objectives: The purpose of the present paper is to review available information on the treatment of peri-implant mucositis and peri-implantitis.Materials and Methods: The results of animal research and human studies are presented. Proposed strategies for the treatment of peri-implantitis presented in the literature are also included.Results: Most of the information accessible at this time derives from case reports. The reports provide evidence that efforts to reduce the submucosal infection may result in short-term improvements of the peri-implant lesion. They also indicate that regenerative procedures in intrabony peri-implant defects can result in the formation of new bone.Conclusions: Several uncertainties remain regarding the treatment of peri-implantitis. Properly conducted long-term follow-ups of consecutively treated cases would seem to be a realistic avenue for accumulation of more information. This may assist in establishing the predictability, magnitude and stability of improvements that can be achieved.
|
|
| 4. |
- Roos-Jansåker, Ann-Marie, et al.
(författare)
-
Treatment of peri-implant infections : a literature review
- 2003
-
Ingår i: Journal of Clinical Periodontology. - : Blackwell Munksgaard. - 0303-6979 .- 1600-051X. ; 30:6, s. 467-485
-
Forskningsöversikt (refereegranskat)abstract
- Objectives: The purpose of the present paper is to review available information on the treatment of peri-implant mucositis and peri-implantitis. Materials and Methods: The results of animal research and human studies are presented. Proposed strategies for the treatment of peri-implantitis presented in the literature are also included. Results: Most of the information accessible at this time derives from case reports. The reports provide evidence that efforts to reduce the submucosal infection may result in short-term improvements of the peri-implant lesion. They also indicate that regenerative procedures in intrabony peri-implant defects can result in the formation of new bone. Conclusions: Several uncertainties remain regarding the treatment of peri-implantitis. Properly conducted long-term follow-ups of consecutively treated cases would seem to be a realistic avenue for accumulation of more information. This may assist in establishing the predictability, magnitude and stability of improvements that can be achieved.
|
|
