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Theragnostic applic...
Theragnostic application of nanoparticle and CRISPR against food-borne multi-drug resistant pathogens
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- Bhattacharjee, Rahul (författare)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India.
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- Nandi, Aditya (författare)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India.
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- Mitra, Priya (författare)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India.
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- Saha, Koustav (författare)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India.
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- Patel, Paritosh (författare)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India.
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- Jha, Ealisha (författare)
- Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India.
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- Panda, Pritam Kumar, PhD Student, 1991- (författare)
- Uppsala universitet,Materialteori
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- Singh, Sushil Kumar (författare)
- Assam Agr Univ, Dept Agr Biotechnol, DBT NECAB, Jorhat 785013, Assam, India.
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- Dutt, Ateet (författare)
- Univ Nacl Autonoma Mexico, Inst Invest Mat, Mexico City, Mexico.
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- Mishra, Yogendra Kumar (författare)
- Univ Southern Denmark, Mads Clausen Inst, NanoSYD, Alsion 2, DK-6400 Sonderborg, Denmark.
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- Verma, Suresh K. (författare)
- Uppsala universitet,Materialteori,Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India.
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Kalinga Inst Ind Technol KIIT DU, KIIT Sch Biotechnol, Bhubaneswar, Orissa, India Materialteori (creator_code:org_t)
- Elsevier, 2022
- 2022
- Engelska.
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Ingår i: MATERIALS TODAY BIO. - : Elsevier. - 2590-0064. ; 15
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Foodborne infection is one of the leading sources of infections spreading across the world. Foodborne pathogens are recognized as multidrug-resistant (MDR) pathogens posing a significant problem in the food industry and healthy consumers resulting in enhanced economic burden, and nosocomial infections. The continued search for enhanced microbial detection tools has piqued the interest of the CRISPR-Cas system and Nanoparticles. CRISPRCas system is present in the bacterial genome of some prokaryotes and is repurposed as a theragnostic tool against MDR pathogens. Nanoparticles and composites have also emerged as an efficient tool in theragnostic applications against MDR pathogens. The diagnostic limitations of the CRISPR-Cas system are believed to be overcome by a synergistic combination of the nanoparticles system and CRISPR-Cas using nanoparticles as vehicles. In this review, we have discussed the diagnostic application of CRISPR-Cas technologies along with their potential usage in applications like phage resistance, phage vaccination, strain typing, genome editing, and antimicrobial. we have also elucidated the antimicrobial and detection role of nanoparticles against foodborne MDR pathogens. Moreover, the novel combinatorial approach of CRISPR-Cas and nanoparticles for their synergistic effects in pathogen clearance and drug delivery vehicles has also been discussed.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
Nyckelord
- Antimicrobial activity
- Diagnosis
- CRISPR-Cas system
- Nanoparticle and MDR food-Borne-pathogens
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Bhattacharjee, R ...
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Nandi, Aditya
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Mitra, Priya
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Saha, Koustav
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Patel, Paritosh
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Jha, Ealisha
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Panda, Pritam Ku ...
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Singh, Sushil Ku ...
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Dutt, Ateet
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Mishra, Yogendra ...
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Verma, Suresh K.
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