| 1. |
- Djurfeldt, Mikael, 1967-, et al.
(författare)
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See-A framework for simulation of biologically detailed and artificial neural networks and systems
- 1999
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Ingår i: Neurocomputing. - 0925-2312 .- 1872-8286. ; 26-27, s. 997-1003
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Tidskriftsartikel (refereegranskat)abstract
- See is a software framework for simulation of biologically detailed and artficial neural networks and systems. It includes a general purpose scripting language, based on Scheme,which also can be used interactively, while the basic framework is written in C++. Models can be built on the Scheme level from `simulation objectsa, each representing a population ofneurons, a projection, etc. The simulator provides a flexible and efficient protocol for data transfer between such objects. See contains a user interface to the parallelized, platformindependent, library SPLIT intended for biologically detailed modeling of large-scale networks and is easy to extend with new user code, both on the C++ and Scheme levels.
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| 2. |
- Abbas, Abdul-Karim, 1959, et al.
(författare)
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Bicarbonate-sensitive cysteine induced elevation of extracellular aspartate and glutamate in rat hippocampus in vitro
- 1997
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Ingår i: Neurochemistry International. - 0197-0186. ; 30:3, s. 253-259
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Tidskriftsartikel (refereegranskat)abstract
- The effect of different concentrations of cysteine (0.125, 0.25, 0.5 and 1 mM) on the net efflux of endogenous amino acids was studied by the incubation of rat hippocampal slices. Addition of cysteine (1 mM) in bicarbonate containing low K+ medium (5 min) selectively increased the basal net efflux of glutamate and aspartate by 370% and 396%, respectively. High K+ media (50 mM) containing cysteine (1 mM) evoked the net efflux of glutamate and aspartate by 1454% and 1019%, respectively. The corresponding effects in control slices without cysteine were 669% and 404%, respectively. No changes were observed on the concentrations of GABA, glutamine and taurine. The cysteine oxidation products, cysteine sulfinate (0.5 μM) and cystine (0.25 mM) were without effects. The effect of cysteine (0.5 mM) was dramatically reduced in media with no added bicarbonate/CO2. Thus, cysteine in a bicarbonate-sensitive manner selectively increases the extracellular concentration of excitotoxic amino acids in adult rat brain in vitro, possibly by interfering with the carrier-mediated glutamate uptake/ release
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| 3. |
- Abbas, Abdul-Karim, 1959, et al.
(författare)
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Bicarbonate-sensitive cysteine induced elevation of extracellular aspartate and glutamate in rat hippocampus in vitro
- 1997
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Ingår i: Neurochemistry International. - 0197-0186. ; 30:3, s. 253-259
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Tidskriftsartikel (refereegranskat)abstract
- The effect of different concentrations of cysteine (0.125, 0.25, 0.5 and 1 mM) on the net efflux of endogenous amino acids was studied by the incubation of rat hippocampal slices. Addition of cysteine (1 mM) in bicarbonate containing low K+ medium (5 min) selectively increased the basal net efflux of glutamate and aspartate by 370% and 396%, respectively. High K+ media (50 mM) containing cysteine (1 mM) evoked the net efflux of glutamate and aspartate by 1 454% and 1 019%, respectively. The corresponding effects in control slices without cysteine were 669% and 404%, respectively. No changes were observed on the concentrations of GABA, glutamine and taurine. The cysteine oxidation products, cysteine sulfinate (0.5 μM) and cystine (0.25 mM) were without effects. The effect of cysteine (0.5 mM) was dramatically reduced in media with no added bicarbonate/CO2. Thus, cysteine in a bicarbonate-sensitive manner selectively increases the extracellular concentration of excitotoxic amino acids in adult rat brain in vitro, possibly by interfering with the carrier-mediated glutamate uptake/ release
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| 4. |
- Daerga, Per-Anders, et al.
(författare)
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Byggsatsfönster. Utveckling av två prototypfönster
- 1998
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Den här rapporten handlar om byggsatsfönster i trä. Tyngdpunkten ligger på konstruktion och funktion, men även ekonomi och marknad ingår. Konceptet har flera tilltalande egenskaper. En byggsats är kompakt, inte lika skrymmande att transportera som fabriksmonterade fönster, vilket bör underlätta exportsatsningar. Vissa komponenter, framför allt isolerrutor men även beslag och tätningar, kan köpas på den lokala marknaden, vilket möjliggör anpassning till brukartraditionen.
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| 5. |
- Ehlers, Stephan, et al.
(författare)
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Asperger syndrome, autism and attention disorders: a comparative study of the cognitive profiles of 120 children.
- 1997
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Ingår i: Journal of Child Psychology and Psychiatry, and Allied Disciplines. - 0021-9630 .- 1469-7610. ; 38:2, s. 207-217
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Tidskriftsartikel (refereegranskat)abstract
- The Wechsler Intelligence Scale for Children-Revised (WISC-R) was applied (in a Swedish version) in 120 children with Asperger syndrome, autistic disorder, and attention disorders. Using stepwise logistic regression analysis, the WISC's discriminating ability was investigated. The overall rate of correct diagnostic classification was 63%. Further, WISC profiles were analysed within each group. The group with autistic disorder was characterised by a peak on Block Design. The Asperger syndrome group had good verbal ability and troughs on Object Assembly and Coding. The group with attention disorders had troughs on Coding and Arithmetic. The results suggest that Kaufman's Verbal Comprehension, Perceptual Organisation and Freedom from Distractibility factors rather than verbal IQ and performance IQ account for the variance on the WISC. Furthermore, the Asperger syndrome and autistic disorder groups differed in respect of "fluid" and "crystallised" cognitive ability.
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| 6. |
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| 8. |
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| 9. |
- Lindén, Anna-Lisa, et al.
(författare)
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Values of Nature in Every-day Life: Words versus Action in Ecological Behaviour
- 1998
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Ingår i: SUSTAINABILITY. The Challenge. People, power and the environment.. - 1551641216 ; , s. 34-41
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The aim of the chapter is to present aspects of generation and gender in relation to ecological behaviour in Sweden. Past studies have compared age groups, sexes or some other classified groups in relation to attitudes and behaviour. The studies present an empirical overview. To get a deeper understanding of attitudes and behaviour we are in need of theoretical renewal with references to both classical and modern sociological theory. A way to go is to focus on value orientation instead of attitudes and to focus on the behavioural dimension of individualism-collectivism instead of specified definitions of ecological behaviour. Values stress perspectives of ethics and morals on environmental problems. The effects of a problem can to some extent by a person be judged as favorable or unfavorable either to individuals or society. It seems as if culture bound experiences during the socialisation processes are important in understanding differences between sexes and generations in aspects of value orientation and ecological behaviour. The discussion ends in a typology of actors, namely the egoistic exploiter, the egoistic conservationist, the collectivistic conservationist, the collectivistic exploiter.
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| 10. |
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| 11. |
- Olsson, Anders, et al.
(författare)
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Load-Carrying Capacity of Damaged Steel Columns with Channel Sections
- 1999
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Ingår i: Journal of Structural Engineering. - 0733-9445. ; 125:3, s. 338-343
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Tidskriftsartikel (refereegranskat)abstract
- The influence of damage on the load-carrying capacity of thin-walled steel columns with channel sections is investigated. The axial load-carrying capacity is evaluated for different profiles, and different damage magnitudes are dealt with. The profiles selected for the analysis are commonly used as upright members in rack and shelving systems in industry. The type of damage corresponds primarily to truck impacts. The strategy presented, however, is generally applicable to different types of profiles, and suitable for parameter studies of different types of damage, load cases, and boundary conditions. The main part of the analysis consists of numerical simulations using the finite-element method, but a verifying laboratory test series is also presented. The results of the numerical simulations are in good agreement with the laboratory tests, and show that even very small defects in the thin-walled columns significantly reduce the axial load-carrying capacity.
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| 12. |
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| 13. |
- Olsson, Anders, et al.
(författare)
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Parameter Studies on Pallet Racks
- 1998
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Pallet racks used in industry are often exposed to large loads, and in some casesresistance to failure is reduced by damage or inadequate handling. The present study was undertaken with the aim of investigating a number of different parameters of importance for the load-carrying capacity of pallet racks. Mainly numerical studies, using the finite element method, are performed, but some experimental work is also presented.The first parameter studied was the influence of damage to upright, cold-formedproles with thin-walled, open cross-sections. Both numerical simulations and laboratory tests showed that small imperfections result in signicant reduction of the load-carrying capacity. A global pallet rack was modelled to investigate the global influence of damaged uprights. Probabilistic computations, containing up to 300 sets of damaged uprights, were performed. The different damage cases were generated with Latin hypercube sampling. Probabilistic computations were also performed to investigate the influence on the load-carrying capacity of uncertainties in the stiffnesses of the connectors between uprights and horizontal beams. The computational results show that the load-carrying capacity depends on the mean stiffness relation of the connectors, but is not very sensitive to the distribution of the connector stiffnesses around the mean stiffness relation. The last part of the work considers different situations where horizontal beams or cross-aisle bracing members are removed from a pallet rack. The influence of this type of handling, considering the load-carrying capacity, is evaluated.
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| 16. |
- Sandberg, Göran, et al.
(författare)
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Failure sensitivity analysis of engineering structures
- 1999
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Ingår i: Computers & Structures. - 0045-7949. ; 72:4-5, s. 525-534
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Tidskriftsartikel (refereegranskat)abstract
- The present paper suggests a method to consider uncertainties in engineering structures in a computational scheme. Latin hypercube sampling is used to prepare input data of probabilistic parameters for subsequent deterministic simulations where the mechanical response is evaluated. The approach is applied on a pallet rack system where damaged columns and connector stiffnesses are considered as probabilistic parameters. The mechanical simulations are performed with the finite element method, and full advantage is taken of existing commercial code.
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| 17. |
- Sterky, Fredrik, et al.
(författare)
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Gene discovery in the wood-forming tissues of poplar : Analysis of 5,692 expressed sequence tags
- 1998
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 95:22, s. 13330-13335
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Tidskriftsartikel (refereegranskat)abstract
- A rapidly growing area of genome research is the generation of expressed sequence tags (ESTs) in which large numbers of randomly selected cDNA clones are partially sequenced. The collection of ESTs reflects the level and complexity of gene expression in the sampled tissue, To date, the majority of plant ESTs are from nonwoody plants such as Arabidopsis, Brassica, maize, and rice. Here, we present a large-scale production of ESTs from the wood-forming tissues of two poplars, Populus tremula L, x tremuloides Michx, and Populus trichocarpa 'Trichobel.' The 5,692 ESTs analyzed represented a total of 3,719 unique transcripts for the two cDNA libraries, Putative functions could be assigned to 2,245 of these transcripts that corresponded to 820 protein functions. Of specific interest to forest biotechnology are the 4% of ESTs involved in various processes of cell wall formation, such as lignin and cellulose synthesis, 5% similar to developmental regulators and members of known signal transduction pathways, and 2% involved in hormone biosynthesis. An additional 12% of the ESTs show ed no significant similarity to any other DNA or protein sequences in existing databases. The absence of these sequences from public databases may indicate a specific role for these proteins in wood formation. The cDNA libraries and the accompanying database are valuable resources for forest research directed toward understanding the genetic control of wood formation and future endeavors to modify wood and fiber properties for industrial use.
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