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1.	Bischoff, Sascha, et al. (författare) Flexible and High-Speed System-Level Performance Analysis using Hardware-Accelerated Simulation 2013 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
2.	Carsten, Hobohm, et al. (författare) Land Use Change and the Future of Biodiversity 2021 Ingår i: Perspectives for Biodiversity and Ecosystems. - Cham : Springer. - 2214-2827 .- 2214-2835. - 9783030577094 ; , s. 451-483 Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract This synthesis report is a meta-analysis of perspectives for biodiversity and ecosystems, with a strong focus on human impacts on the environment, and a work order to enable and manage the protection, survival and evolution of all species on Earth. The goal is to protect nature without any further species loss (Zero Extinction). With this report, we assess alarming signals from the environment; determine the needs of threatened biota and the required actions to manage and protect landscapes and ecosystems; and identify some inescapable tendencies, challenges but also possibilities. The story of humans on Earth is at a critical juncture. Human behaviour is inherently dependent on physical and societal relations, including orientation and positioning within the physical environment. There is no single cultural benefit that is independent of provisioning through ecosystem services. Humans are part of the environment, acquire all needs from it and, as such, depend on its integrity and management for life and well-being. Moreover, if human impacts to the environment continue to increase the risk of rebound effects impacting human life and health will increase as well. Whenever a biome, ecosystem, habitat or species is heavily impacted or threatened with irreversible transformation or extinction, prevailing environmental conditions are relevant and should be observed, analysed and remedied as necessary and where possible. Ecology examines the evolutionary, historical and more recent interplay between biological life and the abiotic environment, while the role of social science and the humanities is to question the physical and social landscape, and how and why it should be protected or influenced, e.g. by nature conservation measures under political and economic, ethical and legal considerations. Thus, for all inter-relationships between natural and sociocultural processes, a joint venture in the form of social-ecological thinking is necessary to combine natural sciences and the humanities. With this contribution, we combine ecological knowledge with social science knowledge (s.l.) through the participation of scientists of many different disciplines. We analyse history and current processes to assess risks, threats and possibilities, and call for an array of regulations and measures that can contribute to halting of biodiversity loss and that assist in achieving a sustainable future. Regulations comprise creativity, cultural incentives, social norms, environmental education and economic investments—such as payments for sustainable agriculture, forestry, and fishery; investments in water, soil and air purity; and much clearer and stronger legal restrictions and consequences around waste streams and environmental degradation. Moreover, a gradual change from profit-oriented economies in the short-run to environmentally-sensitive policies that include systematic environmental programmes in the long term might help to decrease pressure on ecosystems and biota. Such economics might also include the real costs of consumerism, including the impacts of particular products on the environment and on human health. The greatest hurdle for the continued existence of many critically endangered species is the impact of widespread anthropogenic-driven change in the usage of water, air and land, and industry intensification in agriculture, aquaculture, forestry, urbanisation, transportation and mining sectors. However, there is not one simple solution to solve these issues. We conclude that many of the current developments have to be adjusted or gradually altered in a step-wise manner, especially with respect to existing sociocultural behaviours. Therefore, various concepts, decisions and measures should be discussed and implemented at all scales from local to supranational and among researchers, practitioners and politicians.
3.	Leo Sandberg, Elinn, et al. (författare) Matbistånd från Svenska kyrkan 2023 Ingår i: Nyckeln till Svenska kyrkan – en skrift om organisation, verksamhet och ekonomi 2023.. ; , s. 7-27 Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract This is the first time the Church of Sweden's food aid has been mapped statistically and nationally. Food aid is the most common material aid to people in economic vulnerability and a full 86% of the parishes and pastorates in the Church of Sweden work with it. This chapter describes the extent, frequency, composition of the recipient's household, main group affiliation and whether food aid is considered to have increased.
4.	Moberg, Christina, et al. (författare) De unga gör helt rätt när de stämmer staten 2022 Ingår i: Aftonbladet. - 1103-9000. Tidskriftsartikel (populärvet., debatt m.m.)abstract 1 620 forskare och lärare i forskarvärlden: Vi ställer oss bakom Auroras klimatkrav
5.	Sandberg, Andreas, 1984-, et al. (författare) Modeling performance variation due to cache sharing 2013 Ingår i: Proc. 19th IEEE International Symposium on High Performance Computer Architecture. - : IEEE Computer Society. - 9781467355858 ; , s. 155-166 Konferensbidrag (refereegranskat)abstract Shared cache contention can cause significant variability in the performance of co-running applications from run to run. This variability arises from different overlappings of the applications' phases, which can be the result of offsets in application start times or other delays in the system. Understanding this variability is important for generating an accurate view of the expected impact of cache contention. However, variability effects are typically ignored due to the high overhead of modeling or simulating the many executions needed to expose them.This paper introduces a method for efficiently investigating the performance variability due to cache contention. Our method relies on input data captured from native execution of applications running in isolation and a fast, phase-aware, cache sharing performance model. This allows us to assess the performance interactions and bandwidth demands of co-running applications by quickly evaluating hundreds of overlappings.We evaluate our method on a contemporary multicore machine and show that performance and bandwidth demands can vary significantly across runs of the same set of co-running applications. We show that our method can predict application slowdown with an average relative error of 0.41% (maximum 1.8%) as well as bandwidth consumption. Using our method, we can estimate an application pair's performance variation 213x faster, on average, than native execution.
6.	Amanullah, Rahman, et al. (författare) Diversity in extinction laws of Type Ia supernovae measured between 0.2 and 2 μm 2015 Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 453:3, s. 3300-3328 Tidskriftsartikel (refereegranskat)abstract We present ultraviolet (UV) observations of six nearby Type Ia supernovae (SNe Ia) obtained with the Hubble Space Telescope, three of which were also observed in the near-IR (NIR) with Wide-Field Camera 3. UV observations with the Swift satellite, as well as ground-based optical and NIR data provide complementary information. The combined data set covers the wavelength range 0.2-2 mu m. By also including archival data of SN 2014J, we analyse a sample spanning observed colour excesses up to E(B - V) = 1.4 mag. We study the wavelength-dependent extinction of each individual SN and find a diversity of reddening laws when characterized by the total-to-selective extinction R-V. In particular, we note that for the two SNe with E(B - V) greater than or similar to 1 mag, for which the colour excess is dominated by dust extinction, we find R-V = 1.4 +/- 0.1 and R-V = 2.8 +/- 0.1. Adding UV photometry reduces the uncertainty of fitted R-V by similar to 50 per cent allowing us to also measure R-V of individual low-extinction objects which point to a similar diversity, currently not accounted for in the analyses when SNe Ia are used for studying the expansion history of the Universe.
7.	Andersson, Anders, et al. (författare) A transcriptional timetable of autumn senescence 2004 Ingår i: Genome Biology. - : Springer Science and Business Media LLC. - 1465-6906 .- 1474-760X. ; 5:4, s. R24- Tidskriftsartikel (refereegranskat)abstract Background We have developed genomic tools to allow the genus Populus (aspens and cottonwoods) to be exploited as a full-featured model for investigating fundamental aspects of tree biology. We have undertaken large-scale expressed sequence tag (EST) sequencing programs and created Populus microarrays with significant gene coverage. One of the important aspects of plant biology that cannot be studied in annual plants is the gene activity involved in the induction of autumn leaf senescence. Results On the basis of 36,354 Populus ESTs, obtained from seven cDNA libraries, we have created a DNA microarray consisting of 13,490 clones, spotted in duplicate. Of these clones, 12,376 (92%) were confirmed by resequencing and all sequences were annotated and functionally classified. Here we have used the microarray to study transcript abundance in leaves of a free-growing aspen tree (Populus tremula) in northern Sweden during natural autumn senescence. Of the 13,490 spotted clones, 3,792 represented genes with significant expression in all leaf samples from the seven studied dates. Conclusions We observed a major shift in gene expression, coinciding with massive chlorophyll degradation, that reflected a shift from photosynthetic competence to energy generation by mitochondrial respiration, oxidation of fatty acids and nutrient mobilization. Autumn senescence had much in common with senescence in annual plants; for example many proteases were induced. We also found evidence for increased transcriptional activity before the appearance of visible signs of senescence, presumably preparing the leaf for degradation of its components.
8.	Andersson, Christer, et al. (författare) Manifest för lämplig styrning av hälso- och sjukvården 2018 Ingår i: Läkartidningen. - 0023-7205. ; 115:3 Tidskriftsartikel (refereegranskat)
9.	Andersson, Per, et al. (författare) Introducing research on recognition of prior learning 2013 Ingår i: International Journal of Lifelong Education. - : Taylor & Francis. - 0260-1370 .- 1464-519X. ; 32:4, s. 405-411 Tidskriftsartikel (refereegranskat)
10.	Andersson, Per, 1964-, et al. (författare) Introduction : Introducing research on recognition of prior learning 2015. - 1 Ingår i: Recognition of Prior Learning. - London & New York : Routledge. - 9781138955028 ; , s. 1-7 Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract This is the introduction chapter of an anthology of research on recognition of prior learning, previously published as a special issue of the International Journal of Lifelong Education.
11.	Andreas, Sandberg, et al. (författare) Limits on Lyman Continuum Escape from z = 2.2 Hα-emitting Galaxies 2015 Ingår i: Astrophysical Journal Letters. - 2041-8205 .- 2041-8213. ; 814:1 Tidskriftsartikel (refereegranskat)abstract The leakage of Lyman continuum (LyC) photons from star-forming galaxies is an elusive parameter. When observed, it provides a wealth of information on star formation in galaxies and on the geometry of the interstellar medium, and puts constraints on the role of star-forming galaxies in the reionization of the universe. Hα-selected galaxies at trace the highest star formation population at the peak of cosmic star formation history, providing a base for directly measuring LyC escape. Here we present this method and highlight its benefits as well as caveats. We also use the method on 10 Hα emitters in the Chandra Deep Field South at also imaged with the Hubble Space Telescope in the ultraviolet. We find no individual LyC detections, and our stack puts a 5σ upper limit on the average absolute escape fraction of <24%, consistent with similar studies. With future planned observations, the sample sizes should rapidly increase and the method presented here should provide very robust constraints on the escape fraction.
12.	Axelsson, Roland, et al. (författare) Indikatorer för hållbar välfärdsutveckling på stadsdelsnivå 2010 Ingår i: Partnerskap för hållbar välfärdsutveckling. - Örebro : Örebro universitet. - 9789176687338 ; , s. 219-240 Bokkapitel (övrigt vetenskapligt/konstnärligt)
13.	Baliakas, Panagiotis, et al. (författare) Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study 2014 Ingår i: The Lancet Haematology. - 2352-3026. ; 1:2, s. 74-84 Tidskriftsartikel (refereegranskat)abstract Background About 30% of cases of chronic lymphocytic leukaemia (CLL) carry quasi-identical B-cell receptor immunoglobulins and can be assigned to distinct stereotyped subsets. Although preliminary evidence suggests that B-cell receptor immunoglobulin stereotypy is relevant from a clinical viewpoint, this aspect has never been explored in a systematic manner or in a cohort of adequate size that would enable clinical conclusions to be drawn. Methods For this retrospective, multicentre study, we analysed 8593 patients with CLL for whom immunogenetic data were available. These patients were followed up in 15 academic institutions throughout Europe (in Czech Republic, Denmark, France, Greece, Italy, Netherlands, Sweden, and the UK) and the USA, and data were collected between June 1, 2012, and June 7, 2013. We retrospectively assessed the clinical implications of CLL B-cell receptor immunoglobulin stereotypy, with a particular focus on 14 major stereotyped subsets comprising cases expressing unmutated (U-CLL) or mutated (M-CLL) immunoglobulin heavy chain variable genes. The primary outcome of our analysis was time to first treatment, defined as the time between diagnosis and date of first treatment. Findings 2878 patients were assigned to a stereotyped subset, of which 1122 patients belonged to one of 14 major subsets. Stereotyped subsets showed significant differences in terms of age, sex, disease burden at diagnosis, CD38 expression, and cytogenetic aberrations of prognostic significance. Patients within a specific subset generally followed the same clinical course, whereas patients in different stereotyped subsets-despite having the same immunoglobulin heavy variable gene and displaying similar immunoglobulin mutational status-showed substantially different times to first treatment. By integrating B-cell receptor immunoglobulin stereotypy (for subsets 1, 2, and 4) into the well established Dohner cytogenetic prognostic model, we showed these, which collectively account for around 7% of all cases of CLL and represent both U-CLL and M-CLL, constituted separate clinical entities, ranging from very indolent (subset 4) to aggressive disease (subsets 1 and 2). Interpretation The molecular classification of chronic lymphocytic leukaemia based on B-cell receptor immunoglobulin stereotypy improves the Dohner hierarchical model and refines prognostication beyond immunoglobulin mutational status, with potential implications for clinical decision making, especially within prospective clinical trials.
14.	Baliakas, Panagiotis, 1977-, et al. (författare) No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy 2018 Ingår i: Haematologica. - : FERRATA STORTI FOUNDATION. - 0390-6078 .- 1592-8721. ; 103:4, s. E158-E161 Tidskriftsartikel (refereegranskat)
15.	Baliakas, Panagiotis, et al. (författare) Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations. 2015 Ingår i: Blood. - : American Society of Hematology. - 1528-0020 .- 0006-4971. ; 125:5, s. 856-859 Tidskriftsartikel (refereegranskat)abstract An unresolved issue in chronic lymphocytic leukemia (CLL) is whether IGHV3-21 gene usage, in general, or the expression of stereotyped B-cell receptor immunoglobulin defining subset #2 (IGHV3-21/IGLV3-21), in particular, determines outcome for IGHV3-21-utilizing cases. We reappraised this issue in 8593 CLL patients of whom 437 (5%) used the IGHV3-21 gene with 254/437 (58%) classified as subset #2. Within subset #2, immunoglobulin heavy variable (IGHV)-mutated cases predominated, whereas non-subset #2/IGHV3-21 was enriched for IGHV-unmutated cases (P = .002). Subset #2 exhibited significantly shorter time-to-first-treatment (TTFT) compared with non-subset #2/IGHV3-21 (22 vs 60 months, P = .001). No such difference was observed between non-subset #2/IGHV3-21 vs the remaining CLL with similar IGHV mutational status. In conclusion, IGHV3-21 CLL should not be axiomatically considered a homogeneous entity with adverse prognosis, given that only subset #2 emerges as uniformly aggressive, contrasting non-subset #2/IGVH3-21 patients whose prognosis depends on IGHV mutational status as the remaining CLL.
16.	Barkah, Dani, et al. (författare) Evaluation of Automatic Flow Analysis for WCET Calculation on Industrial Real-Time System Code 2008 Ingår i: Proceedings - Euromicro Conference on Real-Time Systems, 2008. - 9780769532981 ; , s. 331-340 Konferensbidrag (refereegranskat)abstract A static Worst-Case Execution Time (WCET) analysis derives upper bounds for the execution times of programs. Such analysts requires information about the possible program flows. The current practice is to provide this information manually, which can be laborious and error-prone. An alternative is to derive this information through an automated flow analysis. In this article, we present a case study where an automatic flowanalysis method was tested on industrial real-time system code. The same code was the subject of an earlier WCET case study, where it was analysed using manual annotations for the flow information. The purpose of the current study was to see to which extent the same flow information could be found automatically. The results show that for the most part this is indeed possible, and we could derive comparable WCET estimates using the automatically generated flow information. In addition, valuable insights were gained on what is needed to make flow analysis methods work on real production code.
17.	Berg, Lotta, et al. (författare) Djurvälfärden vid träning och prov av jakthundar i och utanför vilthägn med vildsvin, älg, björn och hare 2021 Rapport (övrigt vetenskapligt/konstnärligt)abstract Syftet med detta yttrande är att sammanställa aktuell forskning kring djurvälfärden vid träning och prov av jakthundar på vildsvin, älg, björn och hare i vilthägn samt hur de vilda djurens naturliga beteende tillgodoses vid mötet med ett rovdjur och hur detta påverkas av hägnets utformning. Det finns kunskapsluckor inom området då det råder brist på vetenskapliga studier av hur träning och prov i och utanför vilthägn påverkar jakthunden och de vilda djuren. Omfattningen av denna verksamhet är till stora delar okänd för Rådet och området är tämligen oreglerat i lagstiftningen.Träning och prov av jakthundar i hägn sker för att kunna utvärdera hundarnas egenskaper vid jakt. Utfallet av dessa prov används för att undersöka om hunden fungerar och är lämpad för praktisk jakt, men även i avelsarbetet. Skador från björn, vildsvin och älg kan bli allvarliga för jakthunden vid ordinarie jakt. I dagsläget tränas och testas hundar på vildsvin och hare inne i hägnet medan träning och prov av hund på björn och älg sker utanför hägnet med stängsel mellan hund och vilt. Risk för fysiska skador på hund i samband med träning och prov är därför störst i mötet med vildsvin. Djurvälfärdsriskerna för hund omfattar även psykisk påverkan, fysisk överansträngning, värmestress och vätskebrist vid höga utomhustemperaturer samt fysiska skador på grund av hägnets utformning och innehåll. Hur många hundar som skadas i samband med träning på hägnat vilt är dock oklart. Det finns rehabiliteringsanläggningar för jakthundar där hundarna kan tränas på hägnat vilt under mer kontrollerade former och därmed övervinna rädslor och oönskade beteenden. En hund som av olika orsaker blir rädd i samband med jakt, eller som uppvisar oönskade beteenden mot viltet, kan med hjälp av hägnat vilt antingen tränas ytterligare eller uteslutas från att användas vid jakt.En av grundförutsättningarna med träning och prov på vilda djur i hägn är att jaktsituationen ska efterlikna vanlig jakt. Detta innebär att det vilda djuret utsätts för ett hot, vilket i många fall sannolikt innebär stress för det vilda djuret. Hur stor stressituationen blir beror på hur djuret upplever hotet och om det lyckas kontrollera situationen. Vilda djur undviker i regel kontakt med människor och hundar. Att bli förföljd av en hund inne i hägnet är med stor sannolikhet en belastning för det vilda djuret, och även närvaro av hund utanför ett stängsel kan upplevas som ett hot. Träning och prov i hägn varierar med djurslag och anläggning och det vilda djuret har olika förutsättningar att hantera situationen, bland annat beroende på art och individuella skillnader. Förföljelse och jakt innebär sannolikt en betydande stress för vildsvin och hare. Även träning eller prov på älg och björn där hunden befinner sig utanför hägnet kan innebära stress för det vilda djuret. Situationen för det vilda djuret påverkas av faktorer som tidigare erfarenheter av hund och människor, hundens beteende, hur ofta och länge träningen eller proven pågår, hägnets storlek och utformning, samt om hägnet ger viltet möjlighet att undkomma hunden och situationen. Repetitiva moment skulle kunna vänja viltet vid hunden och situationen och för vissa individer innebära ett minskat upplevt hot och stressrespons. Negativ erfarenhet och förväntningar av hundträningen innebär dock en risk för upprepad och ackumulerad stress, vilket kan resultera i att djuret utsätts för ett upprepat och långvarigt lidande. Upplevelsen av repetitiva moment kan påverkas av individuella egenskaper, djurslagsskillnader och det sätt på vilket träningen eller proven utförs. Återkommande exponering för hund kan antingen leda till att det vilda djuret vänjer sig, habituering, eller blir mera känsligt, sensitisering.Hägnets utformning och skötsel har stor betydelse för viltets välfärd och djurskyddsproblem i hägn har noterats. Ett hägnat vilt djur som är kroniskt stressat vid undermålig djurhållning kan ha sämre förutsättningar att hantera den belastning som träning eller prov med hund kan innebära. De hägn för vilda djur som används vid träning och prov av hundar uppvisar stor variation i storlek och utformning. Gemensamt är att hägnet inskränker de vilda djurens naturliga beteenden, exempelvis möjligheten att förflytta sig längre sträckor. I de fall viltet flyttas till ett mindre hägn i samband med träning eller prov reduceras viltets möjligheter till naturliga beteenden ytterligare. Ett hägnat vilt djur som upplever en hotande fara, kan uppleva oro, rädsla och frustration. Detta kan leda till stress, främst när djuret inte kan undkomma eller bemöta hotet på samma sätt som om djuret varit frilevande. Stress uppstår när djuret inte kan kontrollera en situation, eller då kroppen utsätts för psykiska eller fysiska påfrestningar, som vid flyktförsök, värmestress, fysiska skador och smärta.Vildsvin i det vilda är ofta skygga och undviker en potentiell predator om de har möjlighet, men kan också försvara sig mot och även attackera sin förföljare om de blir trängda. Hur vildsvinen påverkas av att hållas instängda i hägn med begränsad möjlighet att undkomma hunden är inte studerat vetenskapligt, men i de fall hund förföljer vildsvinet innebär det troligen betydande rädsla och stress för vildsvinet. Studier har visat att jakt kan leda till att vildsvinen ändrar aktivitetsmönster och vistelseområde. Det finns också en risk att alltför aggressiva hundar tillfogar vildsvinen fysisk skada samtidigt som jakten även riskerar att vildsvin utsätts för värmestress då de har begränsade möjligheter att temperaturreglera sig. Hägn för vildsvin kan vara relativt stora, med en varierad och naturlig biotop. Eftersom hunden kan förfölja vildsvinen inne i hägnet innebär hägnet, oavsett storlek, att vildsvin har begränsade möjligheter att undkomma hunden och jakten i sig är sannolikt stressande. En studie har visat att det kan föreligga allvarliga djurskyddsproblem i vissa vildsvinshägn. Om detta även omfattar tränings- och provhägn skulle detta kunna påverka vildsvinens upplevelse och förmåga att hantera situationen vid jakt i hägn, men detta är inte studerat vetenskapligt.Älgar är flyktdjur som kan springa långa sträckor för att undkomma en angripare, men de kan också försvara sig när de känner sig trängda. Generellt kan älgar relativt lätt hållas i hägn och bli mycket vana vid människor och de förefaller ofta vara tämligen opåverkade vid möten med hundar. Vetenskapliga studier av hur älgar egentligen upplever situationen har Rådet inte funnit. En älg kan göra utfall mot en hund, men även i de fall älgen verkar lugn och opåverkad går det inte att utesluta att konfrontationen med hunden innebär stress för älgen, särskilt då hägnet kraftigt begränsar älgens naturliga flyktbeteende. Under träning eller prov hålls ofta älgen i ett mindre hägn för att hunden ska ges möjlighet att komma nära. Vid träning med hägnad älg har älgen begränsade möjligheter att avlägsna sig från eller komma undan hunden vilket skulle kunna leda till svårigheter för älgen att kontrollera situationen, vilket i sin tur kan ge upphov till stress. Eftersom älgar och hundar hålls åtskilda genom stängsel är risken för fysiska skador hos både hund och älg liten.Vilda björnar undviker normalt kontakt med människor och hundar. Att jagas av en hund har visat sig resultera i såväl beteendemässiga som fysiologiska förändringar vilket tyder på att björnen blir stressad. Exponering för en aktiv, skällande hund utanför hägnet kan upplevas som ett hot och leda till stress. Risken för stress ökar i en anläggning med litet tränings/provhägn, där björnen inte kan undkomma hunden eller kontrollera situationen. I ett litet hägn utan lämpliga biotoper eller fredad zon har björnen små möjligheter att avlägsna sig från hunden eller dölja sig. Situationen för björn vid träning eller prov med hund påverkas av faktorer som tillvänjning, tidigare erfarenheter av hundar och människor, hundens beteende, hur ofta och hur länge hundträningen/proven pågår samt hägnets storlek och utformning och om hägnet ger björnen möjligheter till naturligt beteende och att undkomma hunden. Björnens skötsel och miljö utöver prov-/träningstillfällena, liksom dess individuella förutsättningar påverkar också björnens välfärd, vilket också behöver tas hänsyn till vid bedömningen av björnens situation vid träning och prov med hund.Haren är ett bytesdjur och betraktar hunden som en predator. Haren flyr genom snabba rusher, men kan också försöka förvilla sin efterföljare genom längre hopp och blindspår. I hägn med hare tillåts jakthunden vara lös och jaga haren. Rådet har inte funnit några vetenskapliga studier av harar i den här typen av hägn men det finns studier av harars situation vid möte med hund i andra sammanhang, samt harars reaktion på predatorer generellt. Harar som utsattes för rävlukt minskade sin närvaro i dessa områden och hararnas vaksamhet ökade. Det finns skäl att anta att vilda harar kan reagera på lukt av hund på motsvarande sätt. Man kan anta att stressen för hare vid träningsjakt i hägn liknar den vid vanlig jakt. Skillnaden är att hägnet begränsar harens flyktvägar och även kan begränsa harens möjlighet till normalt flyktbeteende. Hur begränsande hägnet är beror på dess storlek, men eventuellt även dess placering, t.ex. närheten till människor och hundar som ger upphov till syn- eller luktintryck, samt dess utformning, inklusive förekomsten av naturliga förhållanden. Oavsett hägnets storlek och utformning är risken påtaglig att harens välfärd påverkas negativt av att bli jagad. Då harar har en sna
18.	Berg, Lotta, et al. (författare) Grävlingars lidande vid grytanlagsprov med levande grävling 2021 Rapport (övrigt vetenskapligt/konstnärligt)abstract Grävlingar i Sverige jagas idag med flera olika jaktmetoder såsom fällor, vakjakt, jakt med ställande hund ovan jord och jakt med grythund under jord. Grythundar används för jakt, skyddsjakt och eftersök på räv, grävling och mårdhund vilket ställer krav på grythundarnas mentala och fysiska förmågor. Hundarna får inte visa ett uppenbart aggressivt beteende. Olika jaktprov används för att utvärdera hundens mentala och fysiska egenskaper som grythund. Därutöver medger de olika proven en värdering av hundens värde som avelsdjur. Grytanlagsprovens syfte är att bedöma hundars lämplighet vid grytjakt. Provet sker med en levande grävling i ett konstgjort gryt med tre olika gångar som leder fram till en så kallad kittel, där grävlingen är placerad. Kitteln är oftast en rund konstruktion med galler mellan hund och grävling för att undvika fysisk kontakt mellan djuren, kitteln kan vridas för att exponera grävlingen åt rätt håll, mot hunden. Domaren vrider således kitteln för att kunna bedöma hundens arbete med grävlingen. Grävlingar beskrivs som försiktiga djur som ytterst sällan reagerar aggressivt mot människor och som ofta blir skrämda redan vid lukten av en människa. Att vara instängd utan att kunna kontrollera eller undkomma situationen kan vara något av det mest stressande som ett vilt djur kan utsättas för. Det finns få vetenskapliga studier på grävling, men studier som publicerats som rapporter och examensarbeten avseende grävling i konstgryt har tillsammans med en vetenskaplig publikation på fällfångst av grävling visat att grävlingar gjort utfall mot hundar i provgryt, och att grävlingar som fångats i fällor har reagerat med flyktförsök. Djur som saknar möjlighet att kontrollera eller undkomma en stressande situation, kan bli passiva eller till och med uppvisa s.k. inlärd hjälplöshet varvid djuret ger upp och blir apatiskt. Studierna visade också att grävlingar som hade ett passivt beteende i samband med att de hölls instängda i gryt eller fälla ofta hade förhöjd hjärtfrekvens och förändrad kortisolkoncentration i träck, vilket kan tyda på att de upplevde stress. Fastän antalet djur i studierna är litet är detta en indikation på att även till synes lugna grävlingar kan vara stressade. Även om grävlingen vid grytanlagsprovet numera separeras från hunden med ett galler saknar grävlingen möjlighet att komma undan eller kontrollera situationen. Hunden uppfattas också sannolikt som predator av grävlingen. Även en tam eller inte helt vild grävling kan vara rädd för hundar. Grävlingens hundvana eller rädsla för hundar kan vara svår att bedöma eftersom även en till synes lugn grävling kan ha ett stresspåslag. Grävlingens situation och lidande måste bedömas inte bara under själva grytanlagsprovet och träningstillfällena utan under hela grävlingens liv, då den oftast tillbringar 8-10 år i hägn. Välfärden för grävlingen är därför även beroende av hägnets utformning och den dagliga skötseln. Infångande i hägnet liksom transport till provplatsen kan påverka 6 grävlingens välfärd i olika hög grad beroende på faktorer som grävlingens tamhet och tillvänjning, tidigare erfarenhet och förväntan, samt kompetensen hos de personer som hanterar och transporterar djuren. En grävling som är ovan och mindre tam stressas sannolikt mer än en tillvand och tamare individ. Förutom att användas vid grytanlagsprov används grävlingen även när unga hundar ska lära sig jaga. Omfattningen av denna träning är inte reglerad enligt Svenska kennelklubbens reglemente men enligt uppgift ska samma regler följas som vid grytanlagsprov. Det råder brist på vetenskapligt granskade studier på grävlingar och grytanlagsprov och det har inte tillkommit nya studier inom området sedan år 2006. Graden av lidandet för grävlingen beror främst på riskfaktorer som grävlingens oförmåga att kontrollera eller komma undan situationen, grävlingens tidigare erfarenheter, bristande tillvänjning, samt hundens agerande i provgrytet. Beroende på djurets subjektiva upplevelse av hållandet och av de olika ingående momenten kan graden och varaktigheten av lidande skilja sig åt mellan olika individer. För vissa individer kan lidandet röra sig om enstaka men upprepade moment, t.ex. enbart tiden i provgrytet. För andra individer kan lidandet ha en längre varaktighet samt en adderad effekt som ökar graden av lidande om exempelvis hägnets utformning inte möjliggör naturligt beteende och grävlingarna inte är tama vilket kan addera stress under infångande och transport. Sammantaget föreligger en påtaglig risk för lidande, som inte är obetydligt, för grävlingar som används för grytanlagsprov. Det kan på grund av individuella variationer i grävlingarnas beteende under grytanlagsprovet föreligga svårigheter att standardisera proven. Det kan också ifrågasättas om grävlingens beteende vid grytanlagsprov motsvarar ett möte med vild grävling. Hundar kan dessutom få utföra ett slutligt grytjaktprov på vild grävling i naturgryt utan att först ha gjort ett grytanlagsprov. Eventuella negativa effekter av ett icke utfört grytanlagsprov med levande grävling är oklara vid jaktprov på grävling i ett naturgryt. Ett alternativ till prov på levande grävling är att använda en attrapp. Användning av grävlingsattrapp möjliggör en standardisering av grytanlagsproven, samt kan ge ökade och mer lättillgängliga tränings- och testmöjligheter för hundarna. Detta förutsätter dock att attrappen är av tillräckligt hög kvalitet. I Danmark används idag rävattrapper, och det finns attrapp för grävling i Sverige, men utfallet av prov med sådana är oklar. Förutom att grävlingar inte skulle behöva hållas i fångenskap och riskera att utsättas för lidande skulle en väl fungerande och mer lättillgänglig attrapp kunna minska risken för att olämpliga eller otillräckligt tränade hundar utsätter sig själva eller viltet för lidande.
19.	Björnsson, Claes-Ingvar, et al. (författare) The location of the Crab pulsar emission region : restrictions on synchrotron emission models 2010 Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 516, s. A65- Tidskriftsartikel (refereegranskat)abstract Recent observations of the Crab pulsar show no evidence of a spectral break in the infrared regime. It is argued that the observations are consistent with a power-law spectrum in the whole observable infrared-optical range. This is taken as the starting point for evaluating of how self-consistent incoherent synchrotron models fare in a comparison with observations. Inclusion of synchrotron self-absorption proves important as does the restriction on the observed size of the emission region imposed by the relativistic beaming thought to define the pulse profile. It is shown that the observations can be used to derive two independent constraints on the distance from the neutron star to the emission region; in addition to a direct lower limit, an indirect measure is obtained from an upper limit to the magnetic field strength. Both of these limits indicate that the emission region is located at a distance considerably greater than the light cylinder radius. The implications of this result are discussed, and it is emphasized that, for standard incoherent synchrotron models to fit inside the light cylinder, rather special physical conditions need to be invoked.
20.	Bonagas, Nadilly, et al. (författare) Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress 2022 Ingår i: NATURE CANCER. - : Springer Science and Business Media LLC. - 2662-1347. ; 3:2, s. 156- Tidskriftsartikel (refereegranskat)abstract The folate metabolism enzyme MTHFD2 (methylenetetrahydrofolate dehydrogenase/cyclohydrolase) is consistently overexpressed in cancer but its roles are not fully characterized, and current candidate inhibitors have limited potency for clinical development. In the present study, we demonstrate a role for MTHFD2 in DNA replication and genomic stability in cancer cells, and perform a drug screen to identify potent and selective nanomolar MTHFD2 inhibitors; protein cocrystal structures demonstrated binding to the active site of MTHFD2 and target engagement. MTHFD2 inhibitors reduced replication fork speed and induced replication stress followed by S-phase arrest and apoptosis of acute myeloid leukemia cells in vitro and in vivo, with a therapeutic window spanning four orders of magnitude compared with nontumorigenic cells. Mechanistically, MTHFD2 inhibitors prevented thymidine production leading to misincorporation of uracil into DNA and replication stress. Overall, these results demonstrate a functional link between MTHFD2-dependent cancer metabolism and replication stress that can be exploited therapeutically with this new class of inhibitors. Helleday and colleagues describe a nanomolar MTHFD2 inhibitor that causes replication stress and DNA damage accumulation in cancer cells via thymidine depletion, demonstrating a potential therapeutic strategy in AML tumors in vivo.
21.	Born, Andreas, et al. (författare) A man´s world? – The impact of a male dominated environment on female leadership 2018 Rapport (övrigt vetenskapligt/konstnärligt)abstract Despite the significant growth in female labor force participation and educational attainment over the past decades, few women reach leadership positions. In this study, we explore whether male dominated environments, in and of themselves, adversely affect women´s willingness to lead a team. We find that women randomly assigned to male majority teams are less willing to become team leaders than women assigned to female majority teams. Analyses of potential mechanisms show that women in male majority teams are less confident in their relative performance, less influential, and more swayed by others in team discussions. They also (accurately) believe that they will receive less support from team members in a leadership election. Taken together, our results indicate that the absence of women in male dominated contexts may be a self-reinforcing process.
22.	Born, Andreas, et al. (författare) Gender and Willingness to Lead: Does the Gender Composition of Teams Matter? 2022 Ingår i: The Review of Economics and Statistics. - : MIT Press - Journals. - 0034-6535 .- 1530-9142. ; 104:2, s. 259-275 Tidskriftsartikel (refereegranskat)abstract We explore how team gender composition affects willingness to lead by randomly assigning participants in an experiment to male- or female-majority teams. Irrespective of team gender composition, men are substantially more willing than women to lead their team. The pooled sample, and women separately, are more willing to lead female- than male-majority teams. An analysis of mechanisms reveals that a large share of the negative effect of male-majority teams on women's leadership aspirations is accounted for by a negative effect on women's confidence, influence, and expected support from team members.
23.	Bratt, Ola, et al. (författare) The Study of Active Monitoring in Sweden (SAMS) : A randomized study comparing two different follow-up schedules for active surveillance of low-risk prostate cancer 2013 Ingår i: Scandinavian Journal of Urology. - : Medical Journals Sweden AB. - 2168-1805 .- 2168-1813. ; 47:5, s. 347-355 Forskningsöversikt (refereegranskat)abstract Objective. Only a minority of patients with low-risk prostate cancer needs treatment, but the methods for optimal selection of patients for treatment are not established. This article describes the Study of Active Monitoring in Sweden (SAMS), which aims to improve those methods. Material and methods. SAMS is a prospective, multicentre study of active surveillance for low-risk prostate cancer. It consists of a randomized part comparing standard rebiopsy and follow-up with an extensive initial rebiopsy coupled with less intensive follow-up and no further scheduled biopsies (SAMS-FU), as well as an observational part (SAMS-ObsQoL). Quality of life is assessed with questionnaires and compared with patients receiving primary curative treatment. SAMS-FU is planned to randomize 500 patients and SAMS-ObsQoL to include at least 500 patients during 5 years. The primary endpoint is conversion to active treatment. The secondary endpoints include symptoms, distant metastases and mortality. All patients will be followed for 10-15 years. Results. Inclusion started in October 2011. In March 2013, 148 patients were included at 13 Swedish urological centres. Conclusions. It is hoped that the results of SAMS will contribute to fewer patients with indolent, low-risk prostate cancer receiving unnecessary treatment and more patients on active surveillance who need treatment receiving it when the disease is still curable. The less intensive investigational follow-up in the SAMS-FU trial would reduce the healthcare resources allocated to this large group of patients if it replaced the present standard schedule.
24.	Bratt, Ola, 1963, et al. (författare) The Value of an Extensive Transrectal Repeat Biopsy with Anterior Sampling in Men on Active Surveillance for Low-risk Prostate Cancer: A Comparison from the Randomised Study of Active Monitoring in Sweden (SAMS) 2019 Ingår i: European Urology. - : Elsevier BV. - 0302-2838 .- 1873-7560. ; 76:4, s. 461-466 Tidskriftsartikel (refereegranskat)abstract Background: A systematic repeat biopsy is recommended for men starting on active surveillance for prostate cancer, but the optimal number and distribution of cores are unknown. Objective: To evaluate an extensive repeat transrectal biopsy with anterior sampling in men starting on active surveillance. Design, setting, and participants: Randomised multicentre trial. From 2012 to 2016, 340 Swedish men, aged 40-75 yr, with recently diagnosed low-volume Gleason grade group 1 prostate cancer were included. Intervention: Either an extensive transrectal biopsy with anterior sampling (median 19 cores) or a standard transrectal biopsy (median 12 cores). Outcome measurements and statistical analysis: Primary outcome measure: Gleason grade group >= 2 cancer. Secondary outcomes: Cancer in anteriorly directed biopsy cores and postbiopsy infection. Nonparametric statistical tests were applied. Results and limitations: Gleason grade group >= 2 cancer was detected in 16% of 156 men who had an extensive biopsy and in 10% of 164 men who had a standard biopsy, a 5.7% difference (95% confidence interval [CI]-0.2% to 13%, p = 0.09). There was a strong linear association between prostate-specific antigen (PSA) density and cancer in the anteriorly directed biopsy cores. The odds ratios for cancer in the anteriorly directed cores were for any cancer 2.2 (95% CI 1.3-3.9, p = 0.004) and for Gleason grade group >= 2 cancer 2.3 (95% CI 1.2-4.4, p = 0.015) per 0.1-ng/ml/cm(3) increments. Postbiopsy infections were equally common in the two groups. A limitation is that magnetic resonance imaging was not used. Conclusions: The trial did not support general use of the extensive transrectal repeat biopsy template, but cancer in the anteriorly directed cores was common, particularly in men with high PSA density. The higher the PSA density, the stronger the reason to include anterior sampling at a systematic repeat biopsy. Patient summary: This trial compared two different templates for transrectal prostate biopsy in men starting on active surveillance for low-risk prostate cancer. Cancer was often found in the front part of the prostate, which is not sampled on a standard prostate biopsy. (C) 2019 European Association of Urology. Published by Elsevier B.V. All rights reserved.
25.	Bridel, Claire, et al. (författare) Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology : A Systematic Review and Meta-analysis 2019 Ingår i: JAMA Neurology. - : American Medical Association (AMA). - 2168-6149 .- 2168-6157. ; 76:9, s. 1035-1048 Forskningsöversikt (refereegranskat)abstract Importance Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a number of neurological conditions compared with healthy controls (HC) and is a candidate biomarker for neuroaxonal damage. The influence of age and sex is largely unknown, and levels across neurological disorders have not been compared systematically to date.Objectives To assess the associations of age, sex, and diagnosis with NfL in CSF (cNfL) and to evaluate its potential in discriminating clinically similar conditions.Data Sources PubMed was searched for studies published between January 1, 2006, and January 1, 2016, reporting cNfL levels (using the search terms neurofilament light and cerebrospinal fluid) in neurological or psychiatric conditions and/or in HC.Study Selection Studies reporting NfL levels measured in lumbar CSF using a commercially available immunoassay, as well as age and sex.Data Extraction and Synthesis Individual-level data were requested from study authors. Generalized linear mixed-effects models were used to estimate the fixed effects of age, sex, and diagnosis on log-transformed NfL levels, with cohort of origin modeled as a random intercept.Main Outcome and Measure The cNfL levels adjusted for age and sex across diagnoses.Results Data were collected for 10 059 individuals (mean [SD] age, 59.7 [18.8] years; 54.1% female). Thirty-five diagnoses were identified, including inflammatory diseases of the central nervous system (n = 2795), dementias and predementia stages (n = 4284), parkinsonian disorders (n = 984), and HC (n = 1332). The cNfL was elevated compared with HC in a majority of neurological conditions studied. Highest levels were observed in cognitively impaired HIV-positive individuals (iHIV), amyotrophic lateral sclerosis, frontotemporal dementia (FTD), and Huntington disease. In 33.3% of diagnoses, including HC, multiple sclerosis, Alzheimer disease (AD), and Parkinson disease (PD), cNfL was higher in men than women. The cNfL increased with age in HC and a majority of neurological conditions, although the association was strongest in HC. The cNfL overlapped in most clinically similar diagnoses except for FTD and iHIV, which segregated from other dementias, and PD, which segregated from atypical parkinsonian syndromes.Conclusions and Relevance These data support the use of cNfL as a biomarker of neuroaxonal damage and indicate that age-specific and sex-specific (and in some cases disease-specific) reference values may be needed. The cNfL has potential to assist the differentiation of FTD from AD and PD from atypical parkinsonian syndromes.
26.	Brodén, Cyrus, et al. (författare) Low-dose CT-based implant motion analysis is a precise tool for early migration measurements of hip cups : a clinical study of 24 patients 2020 Ingår i: Acta Orthopaedica. - : Informa UK Limited. - 1745-3674 .- 1745-3682. ; 91:3, s. 260-265 Tidskriftsartikel (refereegranskat)abstract Background and purpose - Early implant migration is known to be a predictive factor of clinical loosening in total hip arthroplasty (THA). Radiostereometric analysis (RSA) is the gold standard used to measure early migration in patients. However, RSA requires costly, specialized imaging equipment and the image process is complex. We determined the precision of an alternative, commercially available, CT method in 3 ongoing clinical THA studies, comprising 3 different cups.Materials and methods - 24 CT double examinations of 24 hip cups were selected consecutively from 3 ongoing prospective studies: 2 primary THA (1 cemented and 1 uncemented) and 1 THA (cemented) revision study. Precision of the CT-based implant motion analysis (CTMA) system was calculated separately for each study, using both the surface anatomy of the pelvis and metal beads placed in the pelvis.Results - For the CTMA analysis using the surface anatomy of the pelvis, the precision ranged between 0.07 and 0.31 mm in translation and 0.20° and 0.39° for rotation, respectively. For the CTMA analysis using beads the precision ranged between 0.08 and 0.20 mm in translation and between 0.20° and 0.43° for rotations. The radiation dose ranged between 0.2 and 2.3 mSv.Interpretation - CTMA achieved a clinically relevant and consistent precision between the 3 different hip cups studied. The use of different hip cup types, different CT scanners, or registration method (beads or surface anatomy) had no discernible effect on precision. Therefore, CTMA without the use of bone markers could potentially be an alternative to RSA to measure early migration.
27.	Brum, Wagner S., et al. (författare) Biological variation estimates of Alzheimer's disease plasma biomarkers in healthy individuals 2024 Ingår i: Alzheimer's and Dementia. - 1552-5260 .- 1552-5279. ; 20:2, s. 1284-1297 Tidskriftsartikel (refereegranskat)abstract INTRODUCTION: Blood biomarkers have proven useful in Alzheimer's disease (AD) research. However, little is known about their biological variation (BV), which improves the interpretation of individual-level data. METHODS: We measured plasma amyloid beta (Aβ42, Aβ40), phosphorylated tau (p-tau181, p-tau217, p-tau231), glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL) in plasma samples collected weekly over 10weeks from 20 participants aged 40 to 60 years from the European Biological Variation Study. We estimated within- (CVI) and between-subject (CVG) BV, analytical variation, and reference change values (RCV). RESULTS: Biomarkers presented considerable variability in CVI and CVG. Aβ42/Aβ40 had the lowest CVI (≈ 3%) and p-tau181 the highest (≈ 16%), while others ranged from 6% to 10%. Most RCVs ranged from 20% to 30% (decrease) and 25% to 40% (increase). DISCUSSION: BV estimates for AD plasma biomarkers can potentially refine their clinical and research interpretation. RCVs might be useful for detecting significant changes between serial measurements when monitoring early disease progression or interventions. Highlights Plasma amyloid beta (Aβ42/Aβ40) presents the lowest between- and within-subject biological variation, but also changes the least in Alzheimer's disease (AD) patients versus controls. Plasma phosphorylated tau variants significantly vary in their within-subject biological variation, but their substantial fold-changes in AD likely limits the impact of their variability. Plasma neurofilament light chain and glial fibrillary acidic protein demonstrate high between-subject variation, the impact of which will depend on clinical context. Reference change values can potentially be useful in monitoring early disease progression and the safety/efficacy of interventions on an individual level. Serial sampling revealed that unexpectedly high values in heathy individuals can be observed, which urges caution when interpreting AD plasma biomarkers based on a single test result.
28.	Cambridge Handbook of Institutional Investment and Fiduciary Duty 2014 Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract The Cambridge Handbook of Institutional Investment and Fiduciary Duty is a comprehensive reference work exploring recent changes and future trends in the principles that govern institutional investors and fiduciaries. A wide range of contributors offer new perspectives on dynamics that drive the current emphasis on short-term investment returns. Moreover, they analyze the forces at work in markets around the world which are bringing into sharper focus the systemic effects that investment practices have on the long-term stability of the economy and the interests of beneficiaries in financial, social and environmental sustainability. This volume provides a global and multi-faceted commentary on the evolving standards governing institutional investment, offering guidance for students, researchers and policy-makers interested in finance, governance and other aspects of the contemporary investment world. It also provides investment, business, financial media and legal professionals with the tools they need to better understand and respond to new financial market challenges of the twenty-first century.
29.	Dahlstedt, Magnus, 1975-, et al. (författare) Dissonant futures : occupational trajectories, gender and class in contemporary municipal adult education in Sweden 2018 Ingår i: Journal of Education and Work. - : Informa UK Limited. - 1363-9080 .- 1469-9435. ; 31:1, s. 16-27 Tidskriftsartikel (refereegranskat)abstract The aim of this article is to problematize the ways class and gender are played out in adult students’ narratives about their occupational choice and future. Drawing on Beverly Skeggs, we analyse how students think about future occupations, what motivates them towards these and how they are able to form their future in relation to them. Taking on Sweden as a case, our results show that students’ narratives on their future occupations are classed as well as gendered. In their vision of future occupations, working-class students tend to focus on occupations helping and caring for others, while middle-class students tend to focus on work more as a means of fulfilling themselves as individuals. These differences are also gendered. Female students are more likely than their male counterparts to picture their future occupations in relation to having children and a family. This tells us that in the female students’ narratives, there tends to be a strong focus on caring – for their families as well as in future occupations.
30.	Dahlstedt, Magnus, et al. (författare) Formation of respectable citizens : precarious work and uncertain futures in a f-cked up world 2016 Konferensbidrag (refereegranskat)abstract Drawing on research on gender and class and especially on the work of Beverly Skeggs we analyse adult educational student’s stories of their future occupations and future lives. We argue that these narratives of the future are both gendered and class specific. The results shows that there are echoes from the past, where the working class focused on being diligent, caring, modest and respectable. There is also a gender difference among the working class students, where women picture their future occupations in relation to having children and a family. For the working class female students their future occupations are further often connected to working with people, i.e. as care workers, teachers or for instance physiotherapist – i.e. work that involve caring in one way or another. Different results are seen in the analysis of middle class students that are more likely to focus on their individual self-realisation, where the futures are grander and not so much connected to a specific time and space. Another important result is that the working class students are modest in the narratives of their future occupations. Imagined occupations would mean a certain amount of social mobility, but rather modest ones.
31.	Dahlstedt, Magnus, et al. (författare) Longing to belong : Stories of (non)belonging in multi-ethnic Sweden 2017 Ingår i: Nordic Journal of Migration Research. - : De Gruyter Open. - 1799-649X. ; 7:4, s. 197-204 Tidskriftsartikel (refereegranskat)abstract The aim of this article is to contribute to an understanding of contemporary processes of negotiations concerning belonging and non-belonging to the Swedish social community. Taking on a theoretical approach on belonging inspired by Yuval-Davis and Jacobsen, the article analyses three individual stories of women who have migrated to Sweden. Out of this analysis, focusing on how these women claim their belonging to a Swedish social community at the same time as they in different ways are denied such belonging by others, we may conclude that although each of the stories told is unique and articulates an individual experience, there are striking similarities in how their claims of belonging, with its related implications for belonging, are not acknowledged by others. In a way, these individual stories tell us something about some of the crucial challenges regarding belonging in contemporary multi-ethnic Sweden, as well as Europe.
32.	Dahlstedt, Magnus, et al. (författare) Medborgarskapandets paradoxer : Medborgarskapspositioneringar i berättelser om tillhörighet i migrationens tid 2017 Ingår i: Sociologisk forskning. - : Sveriges Sociologförbund. - 0038-0342 .- 2002-066X. ; 54:1, s. 31-50 Tidskriftsartikel (refereegranskat)abstract Paradoxes of citizen formation: Citizenship positioning in stories about belonging in an era of migrationThis article analyzes the formation of citizenship in today’s multi-ethnic Sweden with a particular focus on how migration renders visible existing citizenship ideals, defined in terms of similarity and difference on the basis of ethno-cultural background. Analysing three individual stories of women who have migrated to Sweden, with different biographies and stories of how they ended up in Sweden, the article focuses on negotiations of the boundaries and contents of citizenship in multi-ethnic Sweden. The point of departure for the analysis is a post-structuralist and discursive approach. In all, the stories address the crucial question of who should be included into the social community and on what conditions – and who should be left out? This particular question is also at the very centre of the political debate in today’s Europe. On the one hand, there are strong arguments about the ’death of multiculturalism’ and demands for new forms of ethno-culturally graduated citizenship – also in Sweden. On the other hand, in Sweden as well as in other European countries, claims for the development of a new and more inclusive societal community have been raised, expanding the rights of citizens to accommodating also those who have been excluded from them.
33.	Dahlstedt, Magnus, et al. (författare) Medborgarskapandets paradoxer [Paradoxes of citizen formation] : Medborgarskapspositioneringar i berättelser om tillhörighet i migrationens tid. [Citizenship positioning in stories about belonging in an era of migration] 2017 Ingår i: Sociologisk forskning. - : Sveriges sociologförbund. - 0038-0342 .- 2002-066X. ; 54:1-2, s. 31-50 Tidskriftsartikel (refereegranskat)abstract This article analyzes the formation of citizenship in today’s multi-ethnic Sweden with a particular focus on how migration renders visible existing citizenship ideals, defined in terms of similarity and difference on the basis of ethno-cultural background. Analysing three individual stories of women who have migrated to Sweden, with different biographies and stories of how they ended up in Sweden, the article focuses on negotiations of the boundaries and contents of citizenship in multi-ethnic Sweden. The point of departure for the analysis is a post-structuralist and discursive approach. In all, the stories address the crucial question of who should be included into the social community and on what conditions – and who should be left out? This particular question is also at the very centre of the political debate in today’s Europe. On the one hand, there are strong arguments about the ’death of multiculturalism’ and demands for new forms of ethno-culturally graduated citizenship – also in Sweden. On the other hand, in Sweden as well as in other European countries, claims for the development of a new and more inclusive societal community have been raised, expanding the rights of citizens to accommodating also those who have been excluded from them.
34.	Dahlstedt, Magnus, et al. (författare) To belong or not to belong : negotiating citizenship in an age of migration 2016 Konferensbidrag (refereegranskat)abstract 2015. More than a million people are seeking refuge in Europe. Over water or over land, children as well as adults are fleeing from war, persecution and poverty. Thousands of them disappear without a trace or drown beneath the waves. Most of the refugees come from the war-torn Syria (International Organisation for Migration 2015). Throughout the member states of the European Union, exceptional policy measures are taken in order to handle the so-called ‘refugee crisis’ – intensified border control, the introduction of ID checks at specific checkpoints as well as within the borders of a country and restrictive rules for the reception of asylum seekers. This precarious situation in Europe addresses a number of crucial questions about the state of citizenship and belonging in contemporary Europe – in an age of large-scale international migration. In an era of international migration established conceptions of citizenship, of who the citizen is or should be, are challenged. International migration highlights some of the fundamental issues of citizenship: which characteristics, abilities or values should the citizen have and how are the relationships between the citizen and society arranged? In the context of international migration certain individuals are seen as ‘naturally’ belonging to the national community they inhabit, guaranteeing a set of rights, while others are seen as not belonging. The question, however, is: Who are included in the societal community, who are excluded, and what conditions are used to decide? This article analyses the formation of citizenship in today’s multi-ethnic Sweden with a particular focus on how migration renders visible existing citizenship ideals, defined in terms of similarity and difference on the basis of ethno-cultural background. Analysing three individual stories of women who have migrated to Sweden, with different biographies, the article focuses on negotiations of the boundaries and contents of citizenship in multi-ethnic Sweden. The point of departure for the analysis is a post-structuralist and discursive approach.
35.	Duval, Florent, et al. (författare) The Lyman alpha reference sample VI. Lyman alpha escape from the edge-on disk galaxy Mrk 1486 2016 Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 587 Tidskriftsartikel (refereegranskat)abstract Context. Recent numerical simulations suggest that the strength of the Lyman alpha (Ly alpha) line of star-forming disk galaxies strongly depends on the inclination at which they are observed: from edge-on to face-on, we expect to see a change from a strongly attenuated Ly alpha line to a strong Ly alpha emission line.Aims. We aim to understand how a strong Ly alpha emission line is able to escape from the low-redshift highly inclined (edge-on) disk galaxy Mrk 1486 (z similar to 0.0338). To our knowledge, this work is the first observational study of Ly alpha transport inside an edge-on disk galaxy.Methods. Using a large set of HST imaging and spectroscopic data, we investigated the interstellar medium (ISM) structure and the dominant source of Ly alpha radiation inside Mrk 1486. Moreover, using a 3D Monte Carlo Ly alpha radiation transfer code, we studied the radiative transfer of Ly alpha and UV continuum photons inside a 3D geometry of neutral hydrogen (HI) and dust that models the ISM structure at the galaxy center. Our numerical simulations predicted the Ly alpha line profile that we then compared to the one observed in the HST/COS spectrum of Mrk 1486.Results. While a pronounced Ly alpha absorption line emerges from the disk of Mrk 1486, very extended Ly alpha structures are observed at large radii from the galaxy center: a large Ly alpha-halo and two very bright Ly alpha regions located slightly above and below the disk plane. The analysis of IFU H alpha spectroscopic data of Mrk 1486 indicates the presence of two bipolar outflowing halos of HI gas at the same location as these two bright Ly alpha regions. Comparing different diagnostic diagrams (such as [OIII](5007)/H beta versus [OI](6300)/H alpha) to photo-and shock-ionization models, we find that the Ly alpha production of Mrk 1486 is dominated by photoionization inside the galaxy disk. From this perspective, our numerical simulations succeed in reproducing the strength and shape of the observed Ly alpha emission line of Mrk 1486 by assuming a scenario in which the Ly alpha photons are produced inside the galaxy disk, travel along the outflowing halos, and scatter on cool HI materials toward the observer.Conclusions. Extended bipolar galactic winds are frequently observed from star-forming disk galaxies. Given the advantage Ly alpha photons take of such outflowing HI materials to easily escape from Mrk 1486, this mechanism may explain the origin of strong Ly alpha emission lines frequently observed from highly inclined galaxies at high-redshift. This therefore challenges the robustness of the expected viewing-angle effect on the Ly alpha properties of star-forming disk galaxies.
36.	Edberg, Jesper, et al. (författare) Laser-induced graphitization of a forest-based ink for use in flexible and printed electronics 2020 Ingår i: npj Flexible Electron.. - : Nature Research. - 2397-4621. ; 4 Tidskriftsartikel (refereegranskat)abstract Laser-induced graphitization (LIG) is a method of converting a carbon-rich precursor into a highly conductive graphite-like carbon by laser scribing. This method has shown great promise as a versatile and low-cost patterning technique. Here we show for the first time how an ink based on cellulose and lignin can be patterned using screen printing followed by laser graphitization. Screen printing is one of the most commonly used manufacturing techniques of printed electronics, making this approach compatible with existing processing of various devices. The use of forest-based materials opens the possibility of producing green and sustainable electronics. Pre-patterning of the ink enables carbon patterns without residual precursor between the patterns. We investigated the effect of the ink composition, laser parameters, and additives on the conductivity and structure of the resulting carbon and could achieve low sheet resistance of 3.8 Ω sq-1 and a high degree of graphitization. We demonstrated that the process is compatible with printed electronics and finally manufactured a humidity sensor which uses lignin as the sensing layer and graphitized lignin as the electrodes.
37.	Ekendahl, Susanne, et al. (författare) Algodling hos massa- och pappersbruk för hållbar produktion av biobränsle – en förstudie 2012 Rapport (refereegranskat)
38.	Eklund, Andreas Aldogan, et al. (författare) Orchestrating an experiential value proposition : the case of a Scandinavian automotive manufacturer 2022 Ingår i: European Business Review. - : Emerald Group Publishing Limited. - 0955-534X .- 1758-7107. ; 34:5, s. 624-641 Tidskriftsartikel (refereegranskat)abstract Purpose This paper aims to advance the theoretical knowledge of how manufacturers develop a multisensory value proposition. Design/methodology/approach An exploratory case study with a global automotive manufacturer was conducted. Personal in-depth interviews with key informants within a manufacturer were performed to obtain in-depth knowledge and insights on how the manufacturer plans and designs a value proposition. Findings This paper reveals how a value proposition is created from a sensory marketing perspective, which includes orchestrating the sensory experience, harmonising sensory cues to ensure they provide a consistent experience, thereby providing a memorable experience. Practical implications Understanding how to offer value might assist managers in tailoring a unique experiential value proposition to position the brand. Originality/value This paper proposes a theoretical framework, enriching the understanding of the underlying mechanisms used to create an experiential value proposition. The framework illustrates that harmonising sensory cues based on brand-related stimuli fosters a memorable experience, which enables consumers to (sub)consciously infer value.
39.	Erlingsson, Gissur Ó, 1974-, et al. (författare) Är reformer smittsamma? : en forskning om tröghet och förändring i kommunsektorn 2023 Rapport (övrigt vetenskapligt/konstnärligt)abstract Den svenska kommunsektorn står inför tuffa utmaningar. Trots att den svenska befolkningen ökat med nästan två miljoner invånare sedan 1970-talets mitt har omkring hälften av kommunerna färre invånare idag jämfört med då. I början av 2023 hade knappt 50 kommuner färre än 8 000 invånare. Det var den minimigräns som 1961 års indelningssakkunniga ansåg vara nödvändig för bärkraftiga kommuner när kommunblocksreformen påbörjades 1962 (SOU 1961:9). Oberoende av invånarantal och skattebas har alla kommuner samma skyldigheter. De bär ansvar för och fördelar resurser kring flera av välfärdsstatens kärnområden, såsom förskola, grundskola, gymnasium, individ- och familjeomsorg samt äldreomsorg. Den ändrade demografi som en åldrande befolkning innebär sätter tveklöst mycket hård press på kommunerna och den svenska välfärden.
40.	Ermedahl, Andreas, et al. (författare) Loop Bound Analysis based on a Combination of Program Slicing, Abstract Interpretation, and Invariant Analysis 2007 Ingår i: OpenAccess Series in Informatics, Volume 6, 2007. - 9783939897057 Konferensbidrag (refereegranskat)abstract Static Worst-Case Execution Time (WCET) analysis is a technique to derive upper bounds for the execution times of programs. Such bounds are crucial when designing and verifying real-time systems. A key component for static derivation of precise WCET estimates is upper bounds on the number of times different loops can be iterated. In this paper we present an approach for deriving upper loop bounds based on a combination of standard program analysis techniques. The idea is to bound the number of different states in the loop which can influence the exit conditions. Given that the loop terminates, this number provides an upper loop bound. An algorithm based on the approach has been implemented in our WCET analysis tool SWEET. We evaluate the algorithm on a number of standard WCET benchmarks, giving evidence that it is capable to derive valid bounds for many types of loops.
41.	Fejes, Andreas, et al. (författare) Adult Education and the Formation of Citizens : A critical Interrogation 2018. - 1 Bok (refereegranskat)abstract Adult Education and the Formation of Citizens turns attention towards normative claims about who adults should become through education, and what capacities and skills adults need to develop to become included in society as ‘full’ citizens. Through these debates, adults are construed as not yet citizens, despite already being citizens in a formal sense; this book problematises such regimes of truth and their related notions of the possibilities and impossibilities of adult education and citizenship. Drawing on empirical examples from the two main adult education institutions in Sweden, folk high schools and municipal adult education, it argues that, through current regimes of truth, these institutions become spaces for the re-shaping of the "abnormal" citizen. The book suggests that only certain futures of citizenship and its educational provision are made possible, while other futures are ignored or even made impossible to imagine. Offering a unique focus on critically problematising the role of adult education in relation to the fostering and shaping of citizens, the book addresses the important contemporary challenges of the role of adult education in a time of migration.Adult Education and the Formation of Citizens will be of great interest to academics, researchers and postgraduate students in the fields of adult education, lifelong learning and education. "Citizenship education is typically viewed as an unproblematic ‘good’ thing that empowers adults to participate fully in a democratic society. In this fascinating volume, Andreas Fejes and his colleagues outline the normative nature of citizenship education and challenge the idea that those not receiving such education are somehow ‘less than’ full citizens. Drawing on Foucault’s ideas they analyse conceptions of citizenship and practices of education as regimes of truth, and explore the ways that power relations shape citizenship as a process of inclusion and exclusion." Stephen Brookfield, John Ireland Endowed Chair, University of St. Thomas, Minneapolis-St. Paul, USA."Never has there been time when we need more strategic adult education oriented to formal, nonformal and informal sectors, to address the ongoing crises in citizenship and global civil society. In putting adult education at the centre, the authors not only fill a deep gap in citizenship education, they push for more careful consideration of the many challenges citizens face globally. This book is a must read for those of us interested in the discourses of citizenship, adult education, and global civil society." Leona M. English is Professor of Adult Education at St. Francis Xavier University, Canada.
42.	Fejes, Andreas, 1977-, et al. (författare) Adult Education and the Formation of Citizens : A critical Interrogation 2018 Bok (refereegranskat)abstract Adult Education and the Formation of Citizens turns attention towards normative claims about who adults should become through education, and what capacities and skills adults need to develop to become included in society as ‘full’ citizens. Through these debates, adults are construed as not yet citizens, despite already being citizens in a formal sense; this book problematises such regimes of truth and their related notions of the possibilities and impossibilities of adult education and citizenship.Drawing on empirical examples from the two main adult education institutions in Sweden, folk high schools and municipal adult education, it argues that, through current regimes of truth, these institutions become spaces for the re-shaping of the "abnormal" citizen. The book suggests that only certain futures of citizenship and its educational provision are made possible, while other futures are ignored or even made impossible to imagine. Offering a unique focus on critically problematising the role of adult education in relation to the fostering and shaping of citizens, the book addresses the important contemporary challenges of the role of adult education in a time of migration.Adult Education and the Formation of Citizens will be of great interest to academics, researchers and postgraduate students in the fields of adult education, lifelong learning and education.
43.	Fejes, Andreas, 1977-, et al. (författare) Adult education as a heterotopia of deviation : Ruptures and stability in young adults and migrants lives 2015 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
44.	Fejes, Andreas, et al. (författare) Individualisation in Swedish Adult Education 2016 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
45.	Fejes, Andreas, 1977-, et al. (författare) Individualisation in Swedish adult education and the shaping of neo-liberal subjectivities 2018 Ingår i: Scandinavian Journal of Educational Research. - : Routledge. - 0031-3831 .- 1470-1170. ; 62:3, s. 461-473 Tidskriftsartikel (refereegranskat)abstract In this article we have analysed the ways a discourse on individualisation is taking shape within adult education in Sweden, how it operates, and what effects it has in terms of shaping student subjectivity. Drawing on a post-structural theorisation we analyse interviews with teachers and students in municipal adult education (MAE) and folk high schools (FHS). The analysis illustrates how both institutions contribute to the shaping of individualised subjectivities, although differently. At the end, a general question is raised about what happens with the democratic function of adult education in general, when a discourse on individualisation operates in the ways described, and more specifically, asks what is happening to FHS as an educational practice, that upholds its self-image as a last bastion of a collective notion of learning and subjectivity, and nurturing an educational practice of learning democracy?
46.	Fejes, Andreas, et al. (författare) Individualisation in the citizen formation in Swedish adult education 2016 Konferensbidrag (refereegranskat)abstract In this article we have analysed the ways a discourse on individualisation is taking shape within adult education in Sweden, how it operates, and what effects it has in terms of shaping student subjectivity. Drawing on a post-structural theorisation we analyse interviews with teachers and students in municipal adult education (MAE) and folk high schools (FHS). The analysis illustrates how both institutions contribute to the shaping of individualised subjectivities, although differently. At the end, a general question is raised about what happens with the democratic function of adult education in general, when a discourse on individualisation operates in the ways described, and more specifically, asks what is happening to FHS as an educational practice, that upholds its self-image as a last bastion of a collective notion of learning and subjectivity, and nurturing an educational practice of learning democracy?
47.	Fejes, Andreas, et al. (författare) Individualisering genom det kollektiva i svensk folkhögskola 2015 Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract The aim of this paper presentation is to identify how the principles of democracy and the market are played out in Swedish adult education. More specifically, we focus on how collective and individually oriented notions of what it means to be a citizen, shape student subjectivity. By focusing on both formal adult education (municipal adult education) and non-formal adult education (folk high schools) we wish to illustrate how these principles are mobilized differently, thus shaping different kinds of citizen subjectivities. Drawing on a post structural theorization inspired by the work of Michel Foucault, we analyse interviews with students and teachers at one school for municipal adult education, as well as one folk high school. Our analysis illustrates how an individually oriented citizen is shaped through discourses mobilized in both settings. However, in the folk highs school, individualization is shaped through discourses on collectivization. We argue that such shaping are in line with neoliberal forms of governance.
48.	Fejes, Andreas, 1977-, et al. (författare) Individualisering genom det kollektiva i svensk folkhögskola 2015 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
49.	Fejes, Andreas, 1977-, et al. (författare) Medborgarskap och utbildning för vuxna : Om Komvux, folkhögskola och medborgarskapandets praktiker 2018 Bok (övrigt vetenskapligt/konstnärligt)abstract Utbildning för vuxna lyfts ofta fram som en lösning på en rad aktuella samhällsutmaningar. Allt från miljöfrågor till den mer övergripande målsättningen att skapa ekonomisk tillväxt. Men vuxenutbildningen har också ett tydligt demokratiskt och medborgerligt uppdrag och i denna bok utforskas detta medborgerliga uppdrag utifrån dess grundläggande antaganden, verkningssätt och konsekvenser. Det är en berättelse som å ena sidan handlar om inkludering, erkännande, framtidstro och realiserandet av drömmar, å andra sidan om normalisering, exkludering och villkorad gemenskap. Med andra ord, att bli en god samhällsmedborgare handlar inte enbart om att tillägna sig relevant kunskap. Det är lika mycket en process av att forma en person – dennes självuppfattning och -uttryck – vilket öppnar upp för en diskussion om gränserna för vuxenutbildningens uppdrag. Boken vänder sig till studenter inom lärarutbildningarna, yrkes- verksamma lärare, skolledare, studievägledare, folkbildare och politiker som intresserar sig för frågor om vuxenutbildningens och folkbildningens roll i att fostra framtida medborgare.
50.	Fejes, Andreas, et al. (författare) The shaping neoliberal subjectivities : Dissonant futures 2016 Konferensbidrag (övrigt vetenskapligt/konstnärligt)

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