| 1. |
- Anastasiadou, Elena, et al.
(författare)
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Business Actor Engagement and Perceived Initiator Roles in Platform Development
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Abstract The implications of business actor engagement and industry-specific platform development within business-to-business (B2B) contexts requires more research. While existing literature provides some guidance on common engagement factors and their impact on value outcomes, it primarily focuses on consumer markets, overlooking the complexities of B2B markets. Recent studies highlight the need for mid-range conceptualizations of business actor engagement, emphasizing engagement’s role beyond the customer perspective. Understanding how responding actors perceive initiators in the BAE process is crucial, as it influences the overall engagement and value outcomes. This study addresses this gap by examining how the behavior and perceived role of initiating actors (in the study; Swedish real estate firms developing sustainability services for commercial tenants) impact responding actors’ engagement. Four perceived roles are identified and conceptualized: the diligent, negligent, steward, and dominant initiating actor. The results also offer insights into BAE role dynamics and suggest that digital platform components serve as business actor engagement role amplifier, shaping engagement and platform development
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| 2. |
- Schmidt, Morena Azbel, 1955-
(författare)
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How do you do it anyway?
- 2005
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This study investigates the translation process of three translator students and their production of translated non-fiction texts. The students are followed from an initial examination task over a period of time of 5 years. The translated texts produced during this period are analysed with selected methods of text analysis, which is compared to their source texts. The text analysis focuses on certain grammatical features that are known to generate problems for translators with the language pair Russian – Swedish. The results of the analysis show that the systematic differences in the languages involved are not as problematic as expected for the participants. Writing skills in the TL, translation principles and initial beliefs as well as the individual’s approach concerning the task of a translator turn out to have the most significant influences on the participants’ performance. In a complementary analysis, introspection data obtained from concurrent verbalisations are analysed according to a model that allows indicating and classifying marked processing in the translations. The role of contrastive language knowledge is especially emphasised in this part of the study. The results are put in relation to each other to obtain a picture of the individual development of the participating translator students. The three case studies show that each participant developed his/her competence during the time of the study. They also show that this development stays within a conceptual frame set by the participants before they started their training as translators. The implications for translator training that can be drawn from this study are mainly concerned with the importance of writing skills in the TL, contrastive language knowledge and the importance of questioning individual beliefs and principles concerning the task of the translator as well as approaches to translating.
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| 3. |
- Ahmad, MS, et al.
(författare)
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A patient satisfaction survey and educational package to improve the care of people hospitalised with COVID-19: a quality improvement project, Liverpool, UK
- 2021
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Ingår i: Wellcome open research. - : F1000 Research Ltd. - 2398-502X. ; 6, s. 222-
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Tidskriftsartikel (refereegranskat)abstract
- Background: The perspectives and experiences of people hospitalised with COVID-19 have been under-reported during the coronavirus pandemic. We developed and conducted a COVID-19 patient satisfaction survey in a large university-affiliated secondary healthcare centre in Liverpool, UK, during Europe’s first coronavirus wave (April-June 2020). The survey found that care was rated highly, including among people of Black Asian and Minority Ethnic (BAME) backgrounds. However, sleep-quality and communication about medications and discharge-planning were identified as areas for improvement. Methods: To improve care for people with COVID-19 admitted to our centre, we designed an educational package for healthcare professionals working on COVID-19 wards. The package, implemented in August 2020, included healthcare worker training sessions on providing holistic care and placement of “Practice Pointers” posters. Patient satisfaction was re-evaluated during the second/third COVID-19 waves in Liverpool (September 2020 - February 2021). Results: Across waves, most (95%) respondents reported that they would recommend our hospital to friends and/or family and rated overall care highly. Comparison of the responses of second/third-wave respondents (n=101) with first-wave respondents (n=94) suggested improved patient satisfaction across most care domains but especially those related to having worries and fears addressed and being consulted about medications and their side-effects. Conclusions: People admitted with COVID-19 to our centre in Liverpool, including those from BAME backgrounds, rated the care they received highly. A simple education package improved the feedback on care received by respondents between the first and second/third waves. These UK-first findings are informing regional strategies to improve person-centred care of hospitalised people with COVID-19.
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| 4. |
- Bakkman, Linda, et al.
(författare)
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Reduced respiratory capacity in muscle mitochondria of obese subjects.
- 2010
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Ingår i: Obesity Facts. - : S. Karger AG. - 1662-4025 .- 1662-4033. ; 3:6, s. 371-5
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND/AIMS: The extent of weight gain varies among individuals despite equal calorie overconsumption. Furthermore, weight gain is often less than expected from energy excess. This suggests differences in metabolic efficiency and basal metabolism. Since mitochondrial uncoupling accounts for a substantial portion of the basal metabolic rate, we compared skeletal muscle mitochondrial respiration in obese subjects to normal-weight reference groups with various degrees of physical activity.METHODS: Muscle biopsies were taken from the vastus lateralis muscle of 9 healthy obese subjects (BMI 40 ± 3). Mitochondria were isolated and analyzed for coupled (state 3) and uncoupled (state 4) respirations as well as mitochondrial efficiency (P/O ratio) using pyruvate as a substrate. Respiratory data were compared to reference groups A, normal-weight untrained (BMI 24 ± 0.7), and B, normal-weight trained (BMI 24 ± 0.6).RESULTS: Obese subjects had a decreased respiratory capacity per mitochondrial volume compared to the reference groups: this was evident in state 4 (65% and 35% of reference group A and B, respectively) and state 3 (53% and 29% of A and B, respectively) (p < 0.05).CONCLUSION: Obese subjects had a low capacity for fuel oxidation, which may play a role in the predisposition of obesity. However, whether lower mitochondrial capacity is a cause or a consequence of obesity requires further research.
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| 5. |
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| 6. |
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| 7. |
- Bakkour, Rani, et al.
(författare)
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Molecularly Imprinted Polymers for Compound-Specific Isotope Analysis of Polar Organic Micropollutants in Aquatic Environments
- 2018
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Ingår i: Analytical Chemistry. - : American Chemical Society (ACS). - 0003-2700 .- 1520-6882. ; 90:12, s. 7292-7301
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Tidskriftsartikel (refereegranskat)abstract
- Compound-specific isotope analysis (CSIA) of polar organic micropollutants in environmental waters requires a processing of large sample volumes to obtain the required analyte masses for analysis by gas chromatography/isotoperatio mass spectrometry (GC/IRMS). However, the accumulation of organic matter of unknown isotopic composition in standard enrichment procedures currently compromises the accurate determination of isotope ratios. We explored the use of molecularly imprinted polymers (MIPs) for selective analyte enrichment for C-13/C-12 and N-15/N-14 ratio measurements by GC/IRMS using 1H-benzotriazole, a typical corrosion inhibitor in dishwashing detergents, as example of a widely detected polar organic micropollutant. We developed procedures for the treatment of >10 L of water samples, in which custom-made MIPs enabled the selective cleanup of enriched analytes in organic solvents obtained through conventional solid-phase extractions. Hydrogen bonding interactions between the triazole moiety of 1H-benzotriazole, and the MIP were responsible for selective interactions through an assessment of interaction enthalpies and N-15 isotope effects. The procedure was applied successfully without causing isotope fractionation to river water samples, as well as in- and effluents of wastewater treatment plants containing mu g/L concentrations of 1H-benzotriazole and dissolved organic carbon (DOC) loads of up to 28 mg C/L. MIP-based treatments offer new perspectives for CSIA of organic micropollutants through the reduction of the DOC-to-micropollutant ratios.
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| 8. |
- Baklanov, Alexander, et al.
(författare)
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Modelling of Episodes of Atmospheric Transport and Deposition from Hypothetical Nuclear Accidents on the Kola Peninsula
- 2001
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The precarious condition of several radioactive sources, and the aggravating situation with regard to how waste is accumulating without adequate storage and maintenance capacity on and along the Kola Peninsula have lately become recognised world-wide. Several major problems are related to the military sources, albeit those of a civil origin definitely also need consideration. The Kola-Barents region of the Russian Arctic exceeds, for example, all other regions and countries in the world regarding the concentration and number of nuclear reactors. One important environmental research issues for the Kola Peninsula as well as for northern Europe appears thus to be assessment of possible consequences after hypothetical accidents at such radioactive sources. Analyses of that kind are the main theme for the present project: ‘Radioactive sources on the Kola Peninsula: a radiological sensitivity analysis of potential cases of airborne accidental release’ of the ÖCB research programme ‘Risk and Nuclear Waste: nuclear problems, risk perceptions of, and societal responses to nuclear waste in the Barents region’. It is a progress report for the first year of the project, it has been focused on “modelling of episodes of atmospheric transport and deposition from hypothetical nuclear accidents on the Kola Peninsula. The report includes the results of modelling of atmospheric transport and deposition from potential accidents at the nuclear sites at the Kola Peninsula for meso- and regional scales. Several scenarios of airborne accidental releases are considered. Additionally, for this period an overview of population distribution and preliminary results of radiological effects to the population of the Barents / Scandinavian region.
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| 9. |
- Baklanov, A. V, et al.
(författare)
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Nanosecond and femtosecond probing of the dynamics of the UV-photodissociation of perfluoroethyliodide C2F5I
- 2001
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Ingår i: Journal of Chemical Physics. - : AIP Publishing. - 0021-9606 .- 1089-7690. ; 115:24, s. 11157-11165
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Tidskriftsartikel (refereegranskat)abstract
- The ns photodissociation of perfluoroethyliodide C2F5I at 266 nm has been studied by using the resonant two-photon ionization (R2PI) technique. Recoil anisotropy parameters as well as average translational energy of the I atoms in the fine structure states P-2(1/2) and P-2(3/2) have been determined. The main contribution (99%) to the absorption at 266 nm was found to be caused by a parallel transition to the (3)Q(0) state which gives mainly excited-state atoms I(P-2(1/2)). The ground-state atoms I(P-2(3/2)) were found to appear mainly (88%) from the primarily excited (3)Q(0) state via curve-crossing (3)Q(0)-(1)Q(1) and to a lesser extent (12%) from direct absorption by a perpendicular transition to the (1)Q(1) and (3)Q(1) states. The fs pump-dump technique in combination with ns R2PI probing of the fragments I(P-2(1/2)) and I(P-2(3/2)) and time-of-flight mass spectrometry have been applied to probe the early stage dynamics of the C2F5I molecule on the excited state (3)Q(0) potential energy surface (PES). The evolution time of the excited molecule to the point where the energy gap between the excited state (3)Q(0) and the ground-state potential energy surfaces drops to a value of about 12 440 cm-1 was found to be 52 +/- 13 fs. This time corresponds to about 0.8 Angstrom extension of the C-I bond distance. The molecular dynamics simulation with DFT calculated ground-state PES and (3)Q(0) PES with the shape calculated for methyl iodide found in the literature gives reasonable agreement with the experimental result for the evolution time. (C) 2001 American Institute of Physics.
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| 10. |
- Baklanov, D. V., et al.
(författare)
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Comparison of transendocardial and retrograde coronary venous intramyocardial catheter delivery systems in healthy and infarcted pigs
- 2006
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Ingår i: Catheterization and cardiovascular interventions. - : Wiley-Blackwell. - 1522-1946 .- 1522-726X. ; 68:3, s. 416-423
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Tidskriftsartikel (refereegranskat)abstract
- We compared two routes for myocardial delivery of therapeutics, transendocardial (TE) delivery with an intramyocardial injection catheter, and retrograde coronary venous (RCV) delivery with a balloon occlusion catheter in the interventricular vein. Methods: TE and RCV injection of 15 mu m, neutron-activatable microspheres was compared in healthy pigs (Group I, n = 3), pigs with a 1-week-old myocardial infarction (MI; group II, n = 5), and pigs with a 2-weeks-old MI (group III, n = 4). The MI was induced by a 1-hr balloon occlusion in the LAD. Both methods were compared in the same animal using different microspheres. The RCV catheter allowed for continuous measurement of distal pressure and 2.5 x 10(6) microspheres were injected in 10 ml at 300 mmHg above balloon occlusion pressure. The TE injections were targeted to the infarct zone and 2.5 x 10(6) microspheres were distributed over 10 injections of 200 mu l. Results: The retention of microspheres decreased with increase in MI age, but was comparable between devices within the groups. RCV delivery resulted in (14.3 +/- 0.9)% microsphere retention in Group I, (10.3 +/- 0.2)% in Group II, and (6.4 +/- 0.1)% in group III (P less than 0.05 versus group I). Microsphere retention after TE was (15.1 +/- 0.7)% in group I, (18.9 +/- 0.6)% in group II, (4.1 +/- 0.1)% in Group III (P less than 0.05 versus groups I and II). The RCV catheter delivered primarily to midventricular, antero-septal segments, whereas TE targeted apical areas predominantly. Conclusions: Delivery efficacy was comparable between devices in each group however RCV targeted midventricular areas whereas TE targeted apical areas.
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| 11. |
- Baklanov, Dmitri V., et al.
(författare)
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Live 3D echo guidance of catheter-based endomyocardial injection
- 2005
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Ingår i: Catheterization and cardiovascular interventions. - : Wiley-Blackwell. - 1522-1946 .- 1522-726X. ; 65:3, s. 340-345
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Tidskriftsartikel (refereegranskat)abstract
- Local delivery of therapeutic agents into the myocardium is limited by suboptimal imaging. We evaluated the feasibility and accuracy of live 313 echo to guide left ventricular endomyocardial injection. An intramyocardial injection catheter was positioned in the left ventricle in five healthy Yorkshire pigs using fluoroscopy. All other catheter manipulations were performed with live biplane and 3D echo guidance. In each animal, a total of 12 endomyocardial injections (volume, 50-100 mu l) of echo contrast mixed with blue tissue dye were performed. Four injections, 10 mm apart, were directed to three myocardial target zones: the anterior septum at the mitral valve level (zone 1); the posterolateral wall between the heads of the papillary muscles (zone 2); and the apex (zone 3). The injections were aimed to form a transverse line in zones 1 and 2 and an inverted triangular pyramid in zone 3. The animals were sacrificed, the hearts were inspected and the left ventricular endocardium was examined to create a map of injection marks. Success, defined as a visible injection of tissue dye, was 95%, and accuracy, defined as an injection into the target zone, was 83%. There was no significant difference in accuracy between the zones. Live 3D echo can successfully guide endomyocardial injections by accurately targeting specific myocardial zones, verifying catheter apposition and, when combined with echo contrast, providing real-time visualization of injectate deposition. (c) 2005 Wiley-Liss, Inc.
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| 12. |
- Corrales Compagnucci, Marcelo, et al.
(författare)
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Non-Fungible Tokens as a Framework for Sustainable Innovation in Pharmaceutical R&D: A Smart Contract-Based Platform for Data Sharing and Rightsholder Protection
- 2024
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Ingår i: International Review of Law, Computers & Technology. - 1360-0869. ; 38:1, s. 66-85
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Tidskriftsartikel (refereegranskat)abstract
- Research and Development (R&D) in the pharmaceutical sector traditionally occurred in closed, siloed institutional settings. This approach was a function of a rights-oriented model which framed access and reuse of data (data sharing) as a threat to rights-holders. However, a closed model of explorative collaboration is less suited to today’s more complex scientific ecosystem, where external engagement and dynamic partnering with multiple actors and diverse information sources has become essential. As such, devising alternative approaches is vital in ensuring that opportunities for scientific advances are not lost or innovation stifled.This article introduces a hybrid contractual framework that combines the benefits of the automated functionality of smart contracts and non-fungible tokens embedded in the blockchain with more traditional rights-based licensing schemes. The framework described is based on the outcome of an experimental pilot platform that enabled participants to store, find and reuse data following FAIR data principles. The platform documents real-world physical assets in the drug discovery of chemical molecules in an immutable digital ledger.More generally, smart contracts and non-fungible token’s point us towards an open and global collaborative platform for exploiting and advancing drug research assets. The resulting platform creates mechanisms for resolving issues regarding standardization, interoperability, and disclosure. As such, it overcomes many of the practical hurdles currently obstructing collaboration in pharmaceutical R&D, as well as providing a framework to address the central conflict in drug discovery, namely the demand for greater data sharing and the protection of rights-holder interests.
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| 13. |
- Filate, Tadele Tamenu, 1994, et al.
(författare)
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Aqueous Processed All-Polymer Solar Cells with High Open-Circuit Voltage Based on Low-Cost Thiophene-Quinoxaline Polymers
- 2024
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Ingår i: ACS Applied Materials & Interfaces. - : American Chemical Society (ACS). - 1944-8252 .- 1944-8244. ; 16:10, s. 12886-12896
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Tidskriftsartikel (refereegranskat)abstract
- Eco-friendly solution processing and the low-cost synthesis of photoactive materials are important requirements for the commercialization of organic solar cells (OSCs). Although varieties of aqueous-soluble acceptors have been developed, the availability of aqueous-processable polymer donors remains quite limited. In particular, the generally shallow highest occupied molecular orbital (HOMO) energy levels of existing polymer donors limit further increases in the power conversion efficiency (PCE). Here, we design and synthesize two water/alcohol-processable polymer donors, poly[(thiophene-2,5-diyl)-alt-(2-((13-(2,5,8,11-tetraoxadodecyl)-2,5,8,11-tetraoxatetradecan-14-yl)oxy)-6,7-difluoroquinoxaline-5,8-diyl)] (P(Qx8O-T)) and poly[(selenophene-2,5-diyl)-alt-(2-((13-(2,5,8,11-tetraoxadodecyl)-2,5,8,11-tetraoxatetradecan-14-yl)oxy)-6,7-difluoroquinoxaline-5,8-diyl)] (P(Qx8O-Se)) with oligo(ethylene glycol) (OEG) side chains, having deep HOMO energy levels (∼−5.4 eV). The synthesis of the polymers is achieved in a few synthetic and purification steps at reduced cost. The theoretical calculations uncover that the dielectric environmental variations are responsible for the observed band gap lowering in OEG-based polymers compared to their alkylated counterparts. Notably, the aqueous-processed all-polymer solar cells (aq-APSCs) based on P(Qx8O-T) and poly[(N,N′-bis(3-(2-(2-(2-methoxyethoxy)-ethoxy)ethoxy)-2-((2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-methyl)propyl)naphthalene-1,4,5,8-bis(dicarboximide)-2,6-diyl)-alt-(2,5-thiophene)] (P(NDIDEG-T)) active layer exhibit a PCE of 2.27% and high open-circuit voltage (VOC) approaching 0.8 V, which are among the highest values for aq-APSCs reported to date. This study provides important clues for the design of low-cost, aqueous-processable polymer donors and the fabrication of aqueous-processable OSCs with high VOC
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| 14. |
- Filate, Tadele Tamenu, 1994, et al.
(författare)
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Hydrophilic Conjugated Polymers for Sustainable Fabrication of Deep-Red Light-Emitting Electrochemical Cells
- 2024
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Ingår i: Advanced Materials Technologies. - : John Wiley & Sons. - 2365-709X. ; 9:3
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Tidskriftsartikel (refereegranskat)abstract
- It is crucial to develop functional electronic materials that can be processed from green solvents to achieve environmentally sustainable and cost-efficient printing fabrication of organic electronic devices. Here, the design and cost-efficient synthesis of two hydrophilic and emissive conjugated polymers, TQ-OEG and TQ2F-OEG, are presented, which are rendered hydrophilic through the grafting of oligo(ethylene glycol) (OEG) solubilizing groups onto the thiophene-quinoxaline conjugated backbone and thereby can be processed from a water:ethanol solvent mixture. It is shown that the introduction of the OEG groups enables for a direct dissolution of salts by the neat polymer for the attainment of solid-state ion mobility. These properties are utilized for the design and development of light-emitting electrochemical cells (LECs), the active materials of which can be solution cast from a water:ethanol-based ink. It is specifically shown that such an LEC device, comprising an optimized blend of the TQ2F-OEG emitter and a Li salt as the active material positioned between two air-stabile electrodes, delivers deep-red emission (peak wavelength = 670 nm) with a radiance of 185 µW m−2 at a low drive voltage of 2.3 V. This study contributes relevant information as to how polymers and LEC devices can be designed and fabricated to combine functionality with sustainability.
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| 15. |
- Filatov, Alexander, et al.
(författare)
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Negative differential resistance in magnetic tunnel junction systems
- 2014
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Ingår i: Physica Status Solidi B-Basic Solid State Physics. - : Wiley. - 0370-1972 .- 1521-3951. ; 251:1, s. 172-177
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Tidskriftsartikel (refereegranskat)abstract
- We study the electrophysical properties of the Fe/MgO/Fe magnetic tunnel junctions (MTJ) with impurities. Sample structures are fabricated on top of fine-crystalline glass-ceramic substrates by e-beam evaporation in a relatively low vacuum (approximate to 10(-4)Torr). The influence of the first magnetic layer fabrication conditions on the degradation of the MTJ is explained by the interlayer diffusion. Various models of electrophysical processes in MTJ on polycrystalline substrates are discussed. The current-voltage (I-V) characteristics of the fabricated structures are found to exhibit a region with negative differential resistance, similar to the one in tunneling diodes. We explain this phenomenon by the formation of excitons in the MgO layer modified by the conductive impurity atoms and their diffusion. The obtained results will be useful in the development of MRAM devices containing MTJs and tunneling diodes. (C) 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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| 16. |
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| 17. |
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| 18. |
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| 19. |
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| 20. |
- Ghapanchi, Amir H., et al.
(författare)
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Resources Contributing to Gaining Competitive Advantage for Open Source Software Projects : An Application of Resource-Based Theory
- 2014
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Ingår i: International Journal of Project Management. - : Elsevier. - 0263-7863 .- 1873-4634. ; 32:1, s. 139-152
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Tidskriftsartikel (refereegranskat)abstract
- Open Source Software (OSS) is an important asset in today’s software-intensive society. The success of OSS projects is highly dependent on a number of factors. These factors must be understood and managed as an OSS project progresses. Thus, project management of an OSS project has a decisive role in ensuring the success of its software. The objective of the research is to increase the understanding of the resources affecting the competitiveness of OSS projects. Herewith, the responsiveness of OSS projects to users’ needs is assessed via an investigation of the defect-fixing process. A Resource-Based View of the firm (RBV) is used to build theoretical justifications for a set of hypotheses proposed in this study. Data gathered from 427 OSS projects confirmed that developers’ interest in and users’ contribution to the project as well as frequently updating and releasing the software affect the project’s ability to gain competitive advantage through effective defect-fixing. It is also shown that OSS projects that are more popular and have a higher level of organizational communication than others are more likely to gain competitive advantage through effective defect-fixing. Finally, implications of the results for practitioners and the research community are presented.
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| 21. |
- Gontad, Francisco, et al.
(författare)
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Fabrication of Nb/Pb structures through ultrashort pulsed laser deposition
- 2016
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Ingår i: Journal of Vacuum Science & Technology. A. Vacuum, Surfaces, and Films. - : AMER INST PHYSICS. - 0734-2101 .- 1520-8559. ; 34:4
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Tidskriftsartikel (refereegranskat)abstract
- This work reports the fabrication of Nb/Pb structures with an application as photocathode devices. The use of relatively low energy densities for the ablation of Nb with ultrashort pulses favors the reduction of droplets during the growth of the film. However, the use of laser fluences in this ablation regime results in a consequent reduction in the average deposition rate. On the other hand, despite the low deposition rate, the films present a superior adherence to the substrate and an excellent coverage of the irregular substrate surface, avoiding the appearance of voids or discontinuities on the film surface. Moreover, the low energy densities used for the ablation favor the growth of nanocrystalline films with a similar crystalline structure to the bulk material. Therefore, the use of low ablation energy densities with ultrashort pulses for the deposition of the Nb thin films allows the growth of very adherent and nanocrystalline films with adequate properties for the fabrication of Nb/Pb structures to be included in superconducting radiofrequency cavities. (C) 2016 American Vacuum Society.
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| 22. |
- Gowda, V. Krishne, et al.
(författare)
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Effective interfacial tension in flow-focusing of colloidal dispersions : 3-D numerical simulations and experiments
- 2019
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Ingår i: Journal of Fluid Mechanics. - : CAMBRIDGE UNIV PRESS. - 0022-1120 .- 1469-7645. ; 876, s. 1052-1076
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Tidskriftsartikel (refereegranskat)abstract
- An interface between two miscible fluids is transient, existing as a non-equilibrium state before complete molecular mixing is reached. However, during the existence of such an interface, which typically occurs at relatively short time scales, composition gradients at the boundary between the two liquids cause stresses effectively mimicking an interfacial tension. Here, we combine numerical modelling and experiments to study the influence of an effective interfacial tension between a colloidal fibre dispersion and its own solvent on the flow in a microfluidic system. In a flow-focusing channel, the dispersion is injected as core flow that is hydrodynamically focused by its solvent as sheath flows. This leads to the formation of a long fluid thread, which is characterized in three dimensions using optical coherence tomography and simulated using a volume of fluid method. The simulated flow and thread geometries very closely reproduce the experimental results in terms of thread topology and velocity flow fields. By varying the interfacial tension numerically, we show that it controls the thread development, which can be described by an effective capillary number. Furthermore, we demonstrate that the applied methodology provide the means to measure the ultra-low but dynamically highly significant effective interfacial tension.
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| 23. |
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| 24. |
- Händel, Peter, 1962-, et al.
(författare)
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Frequency rate estimation at high SNR
- 1997
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Ingår i: IEEE Transactions on Signal Processing. - : Institute of Electrical and Electronics Engineers (IEEE). - 1053-587X .- 1941-0476. ; 45:8, s. 2101-2105
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Tidskriftsartikel (refereegranskat)abstract
- The problem of estimating the frequency rate-of-change of complex-valued frequency-modulated signals from noisy observations is considered. The performance of four related estimators is studied, both analytically and by means of simulations, and their relationship to the estimators proposed by Djuric/Kay and Lang/Musicus is established.
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| 25. |
- Händel, Peter, 1962-, et al.
(författare)
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Frequency rate estimation based on fourth order sample moments
- 1996
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Ingår i: 8th IEEE Signal Processing Workshop on Statistical Signal and Array Processing, SSAP'96. ; , s. 391-394
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Konferensbidrag (refereegranskat)abstract
- Estimation of the frequency rate of linear frequency modulated signals based on phase angles of fourth order sample moments is considered. Three low-complexity estimators are proposed whose performance is close to optimal, that is their error variance is close to the Cramer-Rao lower bound
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| 26. |
- Händel, Peter, 1962-
(författare)
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Frequency selective adaptive time delay estimation
- 1999
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Ingår i: IEEE Transactions on Signal Processing. - : Institute of Electrical and Electronics Engineers (IEEE). - 1053-587X .- 1941-0476. ; 47:2, s. 532-535
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Tidskriftsartikel (refereegranskat)abstract
- A frequency-selective algorithm for time delay estimation between two channel data is proposed, and its performance is studied. The adaptive stochastic gradient scheme pro\ides a direct estimate of the time delay, It has a low numerical complexity, and it is an alternative to data prefiltering and time delay estimation when the source and noise components have different spectral characteristics.
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| 27. |
- Händel, Peter, 1962-
(författare)
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High-order Yule-Walker estimation of the parameters of exponentially damped cisoids in noise
- 1993
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Ingår i: Signal Processing. - 0165-1684 .- 1872-7557. ; 32:3, s. 315-328
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Tidskriftsartikel (refereegranskat)abstract
- An approach for the estimation of the frequencies and damping factors of exponentially damped cisoids (complex sinusoids) is presented. The method may be seen as an extension of the method of backward linear prediction and singular value decomposition of Kumaresan and Tufts to the second-order statistics domain. The proposed estimator is interpreted as a high-order Yule-Walker (HOYW) method using a data based covariance matrix. The HOYW method is analysed at high SNR where closed-form expressions for the accuracy of the estimates are derived. By Monte Carlo simulations the HOYW method is applied to data consisting of one and two damped cisoids in additive white noise. The simulation results are compared with the results using the Kumaresan and Tufts method, with the Cramer-Rao bound, and with the derived theoretical results. The method is not statistically efficient, but the comparison shows that the HOYW method outperforms the method of Kumaresan and Tufts in terms of accuracy versus algorithmic complexity and in terms of precision in the cases considered. Due to the above properties the method is suitable to provide fast initial estimates for nonlinear search methods.
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| 28. |
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| 29. |
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| 30. |
- Ilyas, Aamir, et al.
(författare)
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Residual organic matter and microbial respiration in bottom ash: Effects on metal leaching and eco-toxicity.
- 2015
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Ingår i: Waste Management & Research. - 1096-3669. ; 33:9, s. 805-811
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Tidskriftsartikel (refereegranskat)abstract
- A common assumption regarding the residual organic matter, in bottom ash, is that it does not represent a significant pool of organic carbon and, beyond metal-ion complexation process, it is of little consequence to evolution of ash/leachate chemistry. This article evaluates the effect of residual organic matter and associated microbial respiratory processes on leaching of toxic metals (i.e. arsenic, copper, chromium, molybdenum, nickel, lead, antimony and zinc), eco-toxicity of ash leachates. Microbial respiration was quantified with help of a respirometric test equipment OXITOP control system. The effect of microbial respiration on metal/residual organic matter leaching and eco-toxicity was quantified with the help of batch leaching tests and an eco-toxicity assay - Daphnia magna. In general, the microbial respiration process decreased the leachate pH and eco-toxicity, indicating modification of bioavailability of metal species. Furthermore, the leaching of critical metals, such as copper and chromium, decreased after the respiration in both ash types (fresh and weathered). It was concluded that microbial respiration, if harnessed properly, could enhance the stability of fresh bottom ash and may promote its reuse.
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| 31. |
- Ilyas, Aamir
(författare)
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Unsaturated Phase Environmental Processes in MSWI Bottom Ash
- 2013
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Every year, Sweden produces 1.5 million tons of incineration residues from waste to energy plants. Among these residues bottom ash(BA) due to its large volume and good geotechnical quality can be reused as an alternative construction material. However there are some negative environmental impacts of this practice such as leaching of salts and metals to soils and groundwater. Environmental processes occuring in the unsaturated phase can determine BA’s environmental impacts as well as provide interesting insights into improving its reuse. However, due to dominant conceptualisation of BA’s environmental impacts as a saturated phase phenomenon, very little work has been done on understanding the usaturated phase environmental processes. There is virtaully nothing known about BA’s dielectric properties which can be an impediment in the development of innovative tools e.g. microwave based monitoring and metal recovery systems. Similarly, release of hydrogen gas in anaerobic phase is considered a problem and its recovery for beneficial use has not been considered yet. Finally, residual organic matter is known to degrade and support microbial respiratory processes in BA. However, little work has been done on exploring its impact on leaching of metals and eco-toxicity of ash leachates.Therefore, the objective of this thesis was to explorethese unsaturated enviromental processes and highlight their role in envrionmental monitoring, reuse and resource recovery.To achieve this objective, the thesis was divided into three subdomains; 1) physical-dielectrics and non invasive monitoring , 2) chemicalanaerobic corrosion and hydrogen production, and 3) biological-microbial respiration and its impacts on the ash quality. During this work, methods such as frequency domain relectometry, respiration tests, hydrogen evolution experiments, batch leaching and ecotoxicity tests were employed. Methods such as gas chromatocgraphy and scanning electron microscopy(SEM) were also used when needed. For data analysis, statistical techniques such as polynomial regression, hierarchical clustering and principal components analysis (PCA) were used. Moreover, during the work on dielectrics, physical models were also used to establish the relationship between dielectric permittivity and volumetric water content. The results of dielectrics showed that in dry state BA acts a non conductor with strong dispersion tendencies especially at high frequencies.From the measured dielectric spectra, it was possible to estimate the moisture content as well as the effective electrical conductivity of BA.The dielectric properties of BA indicate the potential use of microwaves in noninvasive monitoring of moisture,weathering, residual metal contentand wet metal recovery.The results of hydrogen gas formation showed that the gas production from fresh BA was possible at mild conditions of temperature and pressure, and it showeda promise for commercial development. Comparison of hydrogen production with metal recovery showed that as compared to metal recovery,the reaction of metallic Al with alkaline solutions, to generate hydrogen , was more efficient. From the results on respiration tests, it was found that the respiration in fresh ash played a positive role by lowering the pH, reducing the leaching of critical metals and modifying the ash leachate eco-toxicity. However in case of the weathered ash, the microbial respiration negatively affected the ash quality by increasing the leaching heavy metals. The leaching of metals(Cu, Cr, Mo, Ni, Pb, & Zn) and total organic carbon was further enhanced by the addition of external organic matter. Further work on a bench scale hydrogen recovery system, the use of substrate induced respiration in fresh BA for carbonation and the use of microwaves in environmental monitoring and wet metal recovery is suggested.
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| 32. |
- Ilyas, Danish, et al.
(författare)
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Performance of STBC Cooperative NOMA with Imperfect Successive Interference Cancellation
- 2021
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Ingår i: IEEE International Conference on Communications (ICC). - : IEEE.
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Konferensbidrag (refereegranskat)abstract
- This paper explores the performance gains achieved by space time block coding (STBC)-based non orthogonal multiple access (NOMA) scheme versus regular cooperative NOMA under the influence of imperfect successive interference cancellation (SIC). Imperfection in the SIC process of NOMA causes performance degradation which is proportional to the number of SIC operations involved. It is demonstrated through outage and sum-rate performance that STBC-NOMA maintains a considerable performance margin from conventional cooperative NOMA even under adverse imperfections in SIC. Furthermore, closed-form expressions of signal to interference ratio (SIR) at user equipment (UE) and outage probability for STBC-NOMA under imperfect SIC are also derived and validated.
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| 33. |
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| 34. |
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| 35. |
- Lopes, F. L., et al.
(författare)
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Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder
- 2020
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Ingår i: Translational Psychiatry. - : Springer Science and Business Media LLC. - 2158-3188. ; 10:1
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Tidskriftsartikel (refereegranskat)abstract
- Bipolar disorder is often comorbid with anxiety, which is itself associated with poorer clinical outcomes, including suicide. A better etiologic understanding of this comorbidity could inform diagnosis and treatment. The present study aims to test whether comorbid anxiety in bipolar disorder reflects shared genetic risk factors. We also sought to assess the contribution of genetic risk for anxiety to suicide attempts in bipolar disorder. Polygenic risk scores (PRS) were calculated from published genome-wide association studies of samples of controls and cases with anxiety (n = 83,566) or bipolar disorder (n = 51,710), then scored in independent target samples (totaln = 3369) of individuals with bipolar disorder who reported or denied lifetime anxiety disorders or suicidal attempts in research interviews. Participants were recruited from clinical and nonclinical settings and genotyped for common genetic variants. The results show that polygenic risk for anxiety was associated with comorbid anxiety disorders and suicide attempts in bipolar disorder, while polygenic risk for bipolar disorder was not associated with any of these variables. Our findings point out that comorbid anxiety disorders in bipolar disorder reflect a dual burden of bipolar and anxiety-related genes; the latter may also contribute to suicide attempts. Clinical care that recognizes and addresses this dual burden may help improve outcomes in people living with comorbid bipolar and anxiety disorders.
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| 36. |
- Lopes, Flávia, 1989, et al.
(författare)
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Simplified geodata models for integrated urban and public transport planning
- 2023
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Ingår i: Proceedings of the 26th AGILE Conference on Geographic Information Science. ; 4:32
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Konferensbidrag (refereegranskat)abstract
- The current division between urban and transport planning is a significant obstacle to achieving sustainable urban development. To transform cities towards sustainability, both fields must adopt shared or at least compatible models of the urban systems, namely transport, street and public space networks for all users and urban activities. Although several models and tools have emerged in recent years to facilitate this integration, there are still usability gaps that hinder their wider adoption. One of the gaps is a lack of flexibility to operate at different stages of integrated planning. To address this gap, the study aims to develop a set of aligned and flexible multimodal urban network models and tools to support different stages of planning. This paper focuses on the public transport geodata models, which were built by aggregating a General Transit Feed Specification (GTFS) dataset at various spatial and temporal levels. The aggregation levels range from a baseline data model that is useful for detailed planning stages, up to a topological data model that is suitable for macro scale and strategic planning. By using this unified set of models, the dialogue between the two fields at different integrated planning phases can be facilitated, and decision-making can be enhanced.
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| 37. |
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| 38. |
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| 39. |
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| 40. |
- Mur, Pilar, et al.
(författare)
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Germline variation in the oxidative DNA repair genes NUDT1 and OGG1 is not associated with hereditary colorectal cancer or polyposis
- 2018
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Ingår i: Human Mutation. - : Hindawi Limited. - 1059-7794 .- 1098-1004. ; 39:9, s. 1214-1225
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Tidskriftsartikel (refereegranskat)abstract
- The causal association of NUDT1 (=MTH1) and OGG1 with hereditary colorectal cancer (CRC) remains unclear. Here, we sought to provide additional evidence for or against the causal contribution of NUDT1 and OGG1 mutations to hereditary CRC and/or polyposis. Mutational screening was performed using pooled DNA amplification and targeted next-generation sequencing in 529 families (441 uncharacterized MMR-proficient familial nonpolyposis CRC and 88 polyposis cases). Cosegregation, in silico analyses, in vitro functional assays, and case-control associations were carried out to characterize the identified variants. Five heterozygous carriers of novel (n=1) or rare (n=4) NUDT1 variants were identified. In vitro deleterious effects were demonstrated for c.143G>A p.G48E (catalytic activity and protein stability) and c.403G>T p.G135W (protein stability), although cosegregation data in the carrier families were inconclusive or nonsupportive. The frequency of missense, loss-of-function, and splice-site NUDT1 variants in our familial CRC cohort was similar to the one observed in cancer-free individuals, suggesting lack of association with CRC predisposition. No OGG1 pathogenic mutations were identified. Our results suggest that the contribution of NUDT1 and OGG1 germline mutations to hereditary CRC and to polyposis is inexistent or, at most, negligible. The inclusion of these genes in routine genetic testing is not recommended.
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| 41. |
- Mura, Anna, et al.
(författare)
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Bringing rehabilitation home with an e-health platform to treat stroke patients : study protocol of a randomized clinical trial (RGS@home)
- 2022
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Ingår i: Trials. - : BioMed Central (BMC). - 1745-6215. ; 23:1
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundThere is a pressing need for scalable healthcare solutions and a shift in the rehabilitation paradigm from hospitals to homes to tackle the increase in stroke incidence while reducing the practical and economic burden for patients, hospitals, and society. Digital health technologies can contribute to addressing this challenge; however, little is known about their effectiveness in at-home settings. In response, we have designed the RGS@home study to investigate the effectiveness, acceptance, and cost of a deep tech solution called the Rehabilitation Gaming System (RGS). RGS is a cloud-based system for delivering AI-enhanced rehabilitation using virtual reality, motion capture, and wearables that can be used in the hospital and at home. The core principles of the brain theory-based RGS intervention are to deliver rehabilitation exercises in the form of embodied, goal-oriented, and task-specific action.MethodsThe RGS@home study is a randomized longitudinal clinical trial designed to assess whether the combination of the RGS intervention with standard care is superior to standard care alone for the functional recovery of stroke patients at the hospital and at home. The study is conducted in collaboration with hospitals in Spain, Sweden, and France and includes inpatients and outpatients at subacute and chronic stages post-stroke. The intervention duration is 3 months with assessment at baseline and after 3, 6, and 12 months. The impact of RGS is evaluated in terms of quality of life measurements, usability, and acceptance using standardized clinical scales, together with health economic analysis. So far, one-third of the patients expected to participate in the study have been recruited (N = 90, mean age 60, days after stroke ≥ 30 days). The trial will end in July 2023.DiscussionWe predict an improvement in the patients’ recovery, high acceptance, and reduced costs due to a soft landing from the clinic to home rehabilitation. In addition, the data provided will allow us to assess whether the prescription of therapy at home can counteract deterioration and improve quality of life while also identifying new standards for online and remote assessment, diagnostics, and intervention across European hospitals.
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| 42. |
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| 43. |
- Pettersson Lidbom, Per
(författare)
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Does the size of the legislature affect the size of government? : Evidence from two natural experiments
- 2012
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Ingår i: Journal of Public Economics. - : Elsevier BV. - 0047-2727 .- 1879-2316. ; 96:3-4, s. 269-278
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Tidskriftsartikel (refereegranskat)abstract
- This paper makes use of regression discontinuity designs to estimate the effect of the number of legislators on the size of government. The results indicate a negative effect, i.e., the larger the size of the legislature the smaller is the size of government. This runs counter to conventional wisdom. One potential explanation is that more legislators can better control a budget maximizing bureaucracy. I present evidence that is consistent with the proposed mechanism.
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| 44. |
- Pettersson-Lidbom, Per
(författare)
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Dynamic Commitment and the Soft Budget Constraint An Empirical Test
- 2010
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Ingår i: American Economic Journal. Economic Policy. - : American Economic Association. - 1945-7731 .- 1945-774X. ; 2:3, s. 154-179
-
Tidskriftsartikel (refereegranskat)abstract
- This paper develops an empirical framework for the problem of soft budgets which is explicitly based on a dynamic commitment problem, i e, the inability of a supporting organization to commit itself not to extend more resources ex post to a budget-constrained organization than it was prepared to provide ex ante Swedish local governments are used as a testing ground since the central government distributed a large number of fiscal transfers The estimated soft-budget effect is economically significant on average a local government Increases its debt by more than 20 percent by going from a hard to a soft budget constraint (JEL D82, G32, L32)
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| 45. |
- Pettersson, Magnus, 1980
(författare)
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Emotiv funktion hos könsövergripande personsubstantiv i tyskan. Några resultat från en empirisk studie av feministiska tidskrifter
- 2007
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Ingår i: Språk och kön i nutida och historiskt perspektiv. Studier presenterade vid Den sjätte nordiska konferensen om språk och kön, Uppsala den 6-7 oktober. Redigerade av Britt-Louise Gunnarsson, Sonja Entzenberg, Maria Ohlsson. - 0083-4661. - 9789150619447 ; , s. 243-252
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- This paper examines gender-inclusive personal nouns in contemporary German. These can be constructed in three ways: by means of a split/double form (die Studentinnen und Studenten), the masculine-gender form (die Studenten), and various neutral forms (e.g. die Studierenden). The gender-inclusive masculine gender, which has traditionally been used when both male and female individuals are referred to at the same time, has been severely criticized by feminist linguists in German-speaking countries. They argue that the gender-inclusive masculine, owing to its morphological similarity to the male-specific masculine form, makes women invisible in the German language. The linguistic designation of human beings, with some respect to gender, is an interesting area of research, with links to social and political issues of gender and equality between the sexes. Gender-inclusive personal nouns in German have been a concern of linguistics and also of public debate since the 1970s; however, most studies on the topic focus on quantitative and/or psycholinguistic aspects, whereas pragmatic and functional perspectives and systematic textual analysis as a methodological tool have been relatively little in evidence. In this paper, I apply the functional language model of Roman Jakobson (1960) to gender-inclusive nouns in two articles from the German feminist periodicals, Emma magazine and the journal Feministische Studien. My conclusion is that the use of the masculine gender can be seen as fulfilling the emotive (sender-oriented) function in texts, where otherwise the split and neutral form dominate. When the persons being referred to represent a negative activity or position, the masculine form is used, but when they are positively described, gender-neutral or split forms, which make women visible, are applied. This is a pattern of variation that has also been found in other texts than the two analysed in this paper. The two samples presented in this paper are abbreviated examples of the kind of textual and pragmatic analyses of gender-inclusive nouns that I am undertaking for my doctoral thesis in German linguistics.
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| 46. |
- Pezeshki, Ali, et al.
(författare)
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Empirical canonical correlation analysis in subspaces
- 2004
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Ingår i: Conference Record of the Thirty-Eighth Asilomar Conference on Signals, Systems and Computers. - : IEEE Communications Society. - 0780386221 ; , s. 994-997
-
Konferensbidrag (refereegranskat)abstract
- This paper addresses canonical correlation analysis of two-channel data, when channel covariances are estimated from a limited number of samples, and are not necessarily full-rank. We show that empirical canonical correlations measure the cosines of the principal angles between the row spaces of the data matrices for the two channels. When the number of samples is smaller than the sum of the ranks of the two data matrices, some of the empirical canonical correlations become one, regardless of the two-channel model that generates the samples. In such cases, the empirical canonical correlations may not be used as estimates of correlation between random variables.
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| 47. |
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| 48. |
- Pirotta, Vanessa, et al.
(författare)
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First evidence of bubble-net feeding and the formation of ‘super-groups’ by the east Australian population of humpback whales during their southward migration
- 2021
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Ingår i: Aquatic conservation. - : Wiley. - 1052-7613 .- 1099-0755. ; , s. 1-8
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Tidskriftsartikel (refereegranskat)abstract
- The recovery of overexploited populations is likely to reveal behaviours that may have been present prior to harvest but are only now reappearing as the population size increases. The east Australian humpback whale (Megaptera novaeangliae) population (group V, stock E1) has recovered well from past exploitation and is now estimated to be close to the pre-whaling population size.Humpback whales were thought to follow a ‘feast and famine’ model historically, feeding intensively in high-latitude feeding grounds and then fasting while migrating and in calving grounds; however, there is growing evidence that animals may feed outside of known foraging grounds.This short article reports on the first photographically documented evidence of bubble-net feeding by humpback whales in Australian coastal waters (n = 10 groups observed) and provides the first evidence of a second site in the southern hemisphere for the formation of ‘super-groups’ (n = 6 super-groups at discrete locations).The formation of super-groups may be linked to changes in the type or density of prey available, either along the migratory route or in the feeding grounds of the previous summer. It is also possible that the increased population size following recovery make large group sizes while feeding more common. These findings strongly support evidence that feeding behaviour is not restricted to high-latitude foraging grounds in the Southern Ocean, and that prey consumption prior to leaving the coastal waters of Australia may be a significant component of the migratory ecology of this population.Understanding how environmental variation influences the extent to which humpback whales depend on foraging opportunities along their migratory route, and where feeding occurs, will help to predict how future changes in the ocean will influence whale populations. This will also allow for more effective management measures to reduce the impact of threats during this important period of energy consumption.
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| 49. |
- Pirouz, P., et al.
(författare)
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Microstructural aspects and mechanism of degradation of 4H-SiC PiN diodes under forward biasing
- 2004
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Ingår i: Mater Res Soc Symp Proc. - : Springer Science and Business Media LLC. ; , s. 91-102
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Konferensbidrag (refereegranskat)abstract
- Devices fabricated from the wide bandgap semiconductor SiC have many advantages over those made from conventional semiconductors. Thus, performance characteristics of some 4H-SiC devices can be two orders of magnitude better than equivalent devices made from silicon. On the other hand, new and unexpected problems have emerged with the operation of some SiC devices that need to be understood and solved before further progress can be made in this area. One of the most intriguing problems has been the degradation of bipolar PiN diodes that have major advantages over unipolar Schottky barrier diodes at high blocking voltages. The electrical degradation of the PiN diodes refers to a drop in voltage under extended forward current operation. The degradation appears to be associated with the appearance of stacking faults (SFs) in the entire base region of the diode. In this paper, we discuss some puzzling aspects of stacking fault formation in such diodes. Electroluminescence as well as TEM has been used to investigate the degradation problem and, based on experimental results, the formation of stacking faults within the device, possible sources of partial dislocations responsible for the stacking faults, and the enhanced motion of dislocations under forward biasing are considered.
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| 50. |
- PirouziFard, MirNabi, et al.
(författare)
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First moment approximations for order statistics from the extreme value distribution
- 2007
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Ingår i: Statistical Methodology. - : Elsevier BV. - 1572-3127. ; 4:2, s. 196-203
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Tidskriftsartikel (refereegranskat)abstract
- Approximate expressions of the first moment of the order statistics of standard extreme value distributions are proposed. We compare different previously given approximations with the exact values. The results show that the approximation given here fits the exact values better than previously given models.
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