| 1. |
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| 2. |
- Krasilnikov, A., et al.
(författare)
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Evidence of 9 Be + p nuclear reactions during 2ω CH and hydrogen minority ICRH in JET-ILW hydrogen and deuterium plasmas
- 2018
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 58:2
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Tidskriftsartikel (refereegranskat)abstract
- The intensity of 9Be + p nuclear fusion reactions was experimentally studied during second harmonic (2ω CH) ion-cyclotron resonance heating (ICRH) and further analyzed during fundamental hydrogen minority ICRH of JET-ILW hydrogen and deuterium plasmas. In relatively low-density plasmas with a high ICRH power, a population of fast H+ ions was created and measured by neutral particle analyzers. Primary and secondary nuclear reaction products, due to 9Be + p interaction, were observed with fast ion loss detectors, γ-ray spectrometers and neutron flux monitors and spectrometers. The possibility of using 9Be(p, d)2α and 9Be(p, α)6Li nuclear reactions to create a population of fast alpha particles and study their behaviour in non-active stage of ITER operation is discussed in the paper.
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| 3. |
- Bombarda, F., et al.
(författare)
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Runaway electron beam control
- 2019
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Ingår i: Plasma Physics and Controlled Fusion. - : IOP Publishing. - 1361-6587 .- 0741-3335. ; 61:1
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Tidskriftsartikel (refereegranskat)
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| 4. |
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- 2018
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 58:1
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Forskningsöversikt (refereegranskat)
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| 5. |
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| 9. |
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| 11. |
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| 12. |
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| 13. |
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| 14. |
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| 15. |
- Joffrin, E., et al.
(författare)
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Overview of the JET preparation for deuterium-tritium operation with the ITER like-wall
- 2019
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 59:11
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Forskningsöversikt (refereegranskat)abstract
- For the past several years, the JET scientific programme (Pamela et al 2007 Fusion Eng. Des. 82 590) has been engaged in a multi-campaign effort, including experiments in D, H and T, leading up to 2020 and the first experiments with 50%/50% D-T mixtures since 1997 and the first ever D-T plasmas with the ITER mix of plasma-facing component materials. For this purpose, a concerted physics and technology programme was launched with a view to prepare the D-T campaign (DTE2). This paper addresses the key elements developed by the JET programme directly contributing to the D-T preparation. This intense preparation includes the review of the physics basis for the D-T operational scenarios, including the fusion power predictions through first principle and integrated modelling, and the impact of isotopes in the operation and physics of D-T plasmas (thermal and particle transport, high confinement mode (H-mode) access, Be and W erosion, fuel recovery, etc). This effort also requires improving several aspects of plasma operation for DTE2, such as real time control schemes, heat load control, disruption avoidance and a mitigation system (including the installation of a new shattered pellet injector), novel ion cyclotron resonance heating schemes (such as the three-ions scheme), new diagnostics (neutron camera and spectrometer, active Alfven eigenmode antennas, neutral gauges, radiation hard imaging systems...) and the calibration of the JET neutron diagnostics at 14 MeV for accurate fusion power measurement. The active preparation of JET for the 2020 D-T campaign provides an incomparable source of information and a basis for the future D-T operation of ITER, and it is also foreseen that a large number of key physics issues will be addressed in support of burning plasmas.
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| 16. |
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| 19. |
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| 20. |
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| 21. |
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| 22. |
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| 23. |
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| 24. |
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| 25. |
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Overview of the JET results
- 2015
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 0029-5515 .- 1741-4326. ; 55:10
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Tidskriftsartikel (refereegranskat)
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| 26. |
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| 27. |
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- 2018
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 58:9
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Tidskriftsartikel (refereegranskat)
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| 28. |
- Ablikim, M., et al.
(författare)
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Measurement of e(+)e(-) -> K(K)over-barJ/psi cross sections at center-of-mass energies from 4.189 to 4.600 GeV
- 2018
-
Ingår i: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 97:7
-
Tidskriftsartikel (refereegranskat)abstract
- We investigate the process e(+)e(-) -> K (K) over barJ/psi at center-of-mass energies from 4.189 to 4.600 GeV using 4.7 fb(-1) of data collected by the BESIII detector at the BEPCII collider. The Born cross sections for the reactions e(+)e(-) -> K(+)K(-)J/psi and K(S)(0)K(S)(0)J/psi are measured as a function of center-of-mass energy. The energy dependence of the cross section for e(+)e(-) -> K(+)K(-)J/psi is shown to differ from that for pi(+)pi(-)J/psi in the region around the Y(4260). In addition, there is evidence for a structure around 4.5 GeV in the e(+)e(-) -> K(+)K(-)J/psi cross section that is not present in pi(+)pi(-)J/psi.
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| 29. |
- Ablikim, M., et al.
(författare)
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Amplitude analysis of the pi(0)pi(0) system produced in radiative J/psi decays
- 2015
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Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 92:5
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Tidskriftsartikel (refereegranskat)abstract
- An amplitude analysis of the pi(0)pi(0) system produced in radiative J/psi decays is presented. In particular, a piecewise function that describes the dynamics of the pi(0)pi(0) system is determined as a function of M pi(0)pi(0) from an analysis of the (1.311 +/- 0.011) x 10(9) J/psi decays collected by the BESIII detector. The goal of this analysis is to provide a description of the scalar and tensor components of the pi(0)pi(0) system while making minimal assumptions about the properties or number of poles in the amplitude. Such a model-independent description allows one to integrate these results with other related results from complementary reactions in the development of phenomenological models, which can then be used to directly fit experimental data to obtain parameters of interest. The branching fraction of J/psi -> pi(0)pi(0) is determined to be (1.15 +/- 0.05) x 10(-3), where the uncertainty is systematic only and the statistical uncertainty is negligible.
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| 30. |
- Ablikim, M., et al.
(författare)
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Evidence for e+e−→γηc(1S) at center-of-mass energies between 4.01 and 4.60 GeV
- 2017
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Ingår i: Physical Review D. - 2470-0010 .- 2470-0029. ; 96:5
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Tidskriftsartikel (refereegranskat)abstract
- We present first evidence for the process e(+)e(-) -> gamma eta(c)(1S) at six center-of-mass energies between 4.01 and 4.60 GeV using data collected by the BESIII experiment operating at BEPCII. We measure the Born cross section at each energy using a combination of twelve eta(c)(1S) decay channels. We also combine all six energies under various assumptions for the energy-dependence of the cross section. If the process is assumed to proceed via the Y(4260), we measure a peak Born cross section sigma(peak)(e(+)e(-) -> gamma eta(c)(1S)) = 2.11 +/- 0.49 (stat.) +/- 0.36 (syst.) pb with a statistical significance of 4.2 sigma.
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| 31. |
- Ablikim, M., et al.
(författare)
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Measurement of the e(+)e(-) -> pi(+) pi(-) cross section between 600 and 900 MeV using initial state radiation
- 2016
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Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 753, s. 629-638
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Tidskriftsartikel (refereegranskat)abstract
- We extract the e(+) e(-) -> pi(+) pi(-) cross section in the energy range between 600 and 900 MeV, exploiting the method of initial state radiation. A data set with an integrated luminosity of 2.93 fb(-1) taken at a center-of-mass energy of 3.773 GeV with the BESIII detector at the BEPCII collider is used. The cross section is measured with a systematic uncertainty of 0.9%. We extract the pion form factor vertical bar F pi vertical bar(2) as well as the contribution of the measured cross section to the leading-order hadronic vacuum polarization contribution to (g - 2)(mu). We find this value to be a(mu)(pi pi,LO) (600-900 MeV) = (368.2 +/- 2.5(stat)+/- 3.3(sys)).10(-10), which is between the corresponding values using the BaBar or KLOE data.
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| 32. |
- Ablikim, M., et al.
(författare)
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Measurement of y(CP) in D-0-(D)over-bar(0) oscillation using quantum correlations in e(+)e(-) -> D-0(D)over-bar(0) at root s=3.773 GeV
- 2015
-
Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 744, s. 339-346
-
Tidskriftsartikel (refereegranskat)abstract
- We report a measurement of the parameter y(CP) in D-0-(D) over bar (0) oscillations performed by taking advantage of quantum coherence between pairs of D-0(D) over bar (0) mesons produced in e(+)e(-) annihilations near threshold. In this work, doubly-tagged D-0(D) over bar (0) events, where one D decays to a CP eigenstate and the other D decays in a semileptonic mode, are reconstructed using a data sample of 2.92 fb(-1) collected with the BESIII detector at the center-of-mass energy of root s = 3.773 GeV. We obtain y(CP) = (-2.0 +/- 1.3 +/- 0.7)%, where the first uncertainty is statistical and the second is systematic. This result is compatible with the current world average.
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| 33. |
- Ablikim, M., et al.
(författare)
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Search for the Y(4140) via e(+)e(-) -> gamma phi J/psi at root s=4.23, 4.26 and 4.36 GeV
- 2015
-
Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 91:3
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Tidskriftsartikel (refereegranskat)abstract
- Using data samples collected at center-of-mass energies root s = 4.23, 4.26, and 4.36 GeV with the BESIII detector operating at the BEPCII storage ring, we search for the production of the charmoniumlike state Y(4140) through a radiative transition followed by its decay to phi J/psi. No significant signal is observed and upper limits on sigma[e(+)e(-) -> gamma Y(4140)] . B(Y(4140) -> phi J/psi at the 90% confidence level are estimated as 0.35, 0.28, and 0.33 pb at root s = 4.23, 4.26, and 4.36 GeV, respectively.
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| 34. |
- Ablikim, M., et al.
(författare)
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Searches for isospin-violating transitions chi(c0,2) -> pi(0)eta(c)
- 2015
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Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 91:11
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Tidskriftsartikel (refereegranskat)abstract
- We present the first upper-limit measurement of the branching fractions of the isospin-violating transitions chi(c0,2) -> pi(0)eta(c). The measurements are performed using 106 x 10(6) psi(3686) events accumulated with the BESIII detector at the BEPCII e(+)e(-) collider at a center-of-mass energy corresponding to the psi(3686) mass. We obtained upper limits on the branching fractions at a 90% confidence level of B(chi(c0) -> pi(0)eta(c)) < 1.6 x 10(-3) and B(chi(c2) -> pi(0)eta(c)) < 3.2 x 10(-3).
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| 35. |
- Ablikim, M., et al.
(författare)
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Study of e(+)e(-) -> omega chi(cJ) at Center of Mass Energies from 4.21 to 4.42 GeV
- 2015
-
Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 114:9
-
Tidskriftsartikel (refereegranskat)abstract
- Based on data samples collected with the BESIII detector at the BEPCII collider at nine center of mass energies from 4.21 to 4.42 GeV, we search for the production of e(+)e(-) -> omega chi(cJ) (J = 0, 1, 2). The process e(+)e(-) -> omega chi(c0) is observed for the first time, and the Born cross sections at root s = 4.23 and 4.26 GeV are measured to be (55.4 +/- 6.0 +/- 5.9) and (23.7 +/- 5.3 +/- 3.5) pb, respectively, where the first uncertainties are statistical and the second are systematic. The omega chi(c0) signals at the other seven energies and the e(+)e(-) -> omega chi(c1) and omega chi(c2) signals are not significant, and the upper limits on the cross sections are determined. By examining the omega chi(c0) cross section as a function of center of mass energy, we find that it is inconsistent with the line shape of the Y(4260) observed in e(+)e(-) -> pi(+)pi(-) J/psi Assuming the omega chi(c0) signals come from a single resonance, we extract the mass and width of the resonance to be (4230 +/- 8 +/- 6) MeV/c(2) and (38 +/- 12 +/- 2) MeV, respectively, and the statistical significance is more than 9 sigma.
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| 36. |
- Ablikim, M., et al.
(författare)
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Study of J/psi -> eta phi pi(+)pi(-) at BESIII
- 2015
-
Ingår i: Physical Review D. - 1550-7998 .- 1550-2368. ; 91:5
-
Tidskriftsartikel (refereegranskat)abstract
- invariant mass spectrum of phi f(0)(980) with a statistical significance of greater than 10 sigma. The corresponding mass and width are determined to be M = 2200 +/- 6(stat) +/- 5(syst) MeV/c(2) and Gamma = 104 +/- 15(stat) +/- 15(syst) MeV, respectively, and the product branching fraction is measured to be B(J/psi ->eta Y(2175), Y(2175)->phi f(0)(980), f(0)(980)->pi(+)pi(-)) = (1.20 +/- 0.14(stat)+/- 0.37(syst))x10(-4). The results are consistent within errors with those of previous experiments. We also measure the branching fraction of J/psi ->phi f(1)(1285) with f(1)(1285)->eta pi(+)pi(-) and set upper limits on the branching fractions for J/psi ->phi eta(1405)/phi X(1835)/phi X(1870) with eta(1405)/X(1835)/X(1870)->eta pi(+)pi(-) at the 90% confidence level.
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| 37. |
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| 38. |
- Ablikim, M., et al.
(författare)
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Evidence for e(+)e(-)->gamma chi c1,2 at center-of-mass energies from 4.009 to 4.360 GeV
- 2015
-
Ingår i: Chinese Physics C. - : IOP Publishing. - 1674-1137 .- 2058-6132. ; 39:4
-
Tidskriftsartikel (refereegranskat)abstract
- Using data samples collected at center-of-mass energies of root s=4.009, 4.230, 4.260, and 4.360 GeV with the BESIII detector operating at the BEPCII collider, we perform a search for the process e(+)e(-)->gamma chi(cJ) (J=0, 1, 2) and find evidence for e(+)e(-)->gamma chi(c1) and e(+)e(-)->gamma chi(c2) with statistical significances of 3.0 sigma and 3.4 sigma, respectively. The Born cross sections sigma(B)(e(+)e(-)->gamma chi(cJ)), as well as their upper limits at the 90% confidence level (C.L.) are determined at each center-of-mass energy.
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| 39. |
- Ablikim, M., et al.
(författare)
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Precision measurement of the D*(0) decay branching fractions
- 2015
-
Ingår i: Physical Review D. - 1550-7998 .- 1550-2368 .- 2470-0010. ; 91:3
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Tidskriftsartikel (refereegranskat)abstract
- Using 482 pb(-1) of data taken at root s = 4.009 GeV, we measure the branching fractions of the decays of D*(0) into D-0 pi(0) and D-0 gamma to be B(D*(0) -> D-0 pi(0)) = (65.5 +/- 0.8 +/- 0.5)% and B(D*(0) -> D0 gamma) = (34.5 +/- 0.8 +/- 0.5)%, respectively, by assuming that the D*(0) decays only into these two modes. The ratio of the two branching fractions is B(D*(0) -> D-0 pi(0))/B(D*(0) -> D-0 gamma) = 1.90 +/- 0.07 +/- 0.05, which is independent of the assumption made above. The first uncertainties are statistical and the second ones systematic. The precision is improved by a factor of 3 compared to the present world average values.
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| 40. |
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| 41. |
- Ablikim, M., et al.
(författare)
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Determination of the number of ψ(3686) events at BESIII
- 2018
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Ingår i: Chinese Physics C. - : IOP Publishing. - 1674-1137 .- 2058-6132. ; 42:2
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Tidskriftsartikel (refereegranskat)abstract
- The numbers of psi(3686) events accumulated by the BESIII detector for the data taken during 2009 and 2012 are determined to be (107.0 +/- 0.8)x10(6) and (341.1 +/- 2.1)x10(6), respectively, by counting inclusive hadronic events, where the uncertainties are systematic and the statistical uncertainties are negligible. The number of events for the sample taken in 2009 is consistent with that of the previous measurement. The total number of psi(3686) events for the two data taking periods is (448.1 +/- 2.9) x 10(6).
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| 42. |
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| 43. |
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| 44. |
- Shepherd, L., et al.
(författare)
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Infection-related and -unrelated malignancies, HIV and the aging population
- 2016
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Ingår i: HIV Medicine. - : Wiley. - 1464-2662 .- 1468-1293. ; 17:8, s. 590-600
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives: HIV-positive people have increased risk of infection-related malignancies (IRMs) and infection-unrelated malignancies (IURMs). The aim of the study was to determine the impact of aging on future IRM and IURM incidence. Methods: People enrolled in EuroSIDA and followed from the latest of the first visit or 1 January 2001 until the last visit or death were included in the study. Poisson regression was used to investigate the impact of aging on the incidence of IRMs and IURMs, adjusting for demographic, clinical and laboratory confounders. Linear exponential smoothing models forecasted future incidence. Results: A total of 15 648 people contributed 95 033 person-years of follow-up, of whom 610 developed 643 malignancies [IRMs: 388 (60%); IURMs: 255 (40%)]. After adjustment, a higher IRM incidence was associated with a lower CD4 count [adjusted incidence rate ratio (aIRR) CD4 count < 200 cells/μL: 3.77; 95% confidence interval (CI) 2.59, 5.51; compared with ≥ 500 cells/μL], independent of age, while a CD4 count < 200 cells/μL was associated with IURMs in people aged < 50 years only (aIRR: 2.51; 95% CI 1.40–4.54). Smoking was associated with IURMs (aIRR: 1.75; 95% CI 1.23, 2.49) compared with never smokers in people aged ≥ 50 years only, and not with IRMs. The incidences of both IURMs and IRMs increased with older age. It was projected that the incidence of IRMs would decrease by 29% over a 5-year period from 3.1 (95% CI 1.5–5.9) per 1000 person-years in 2011, whereas the IURM incidence would increase by 44% from 4.1 (95% CI 2.2–7.2) per 1000 person-years over the same period. Conclusions: Demographic and HIV-related risk factors for IURMs (aging and smoking) and IRMs (immunodeficiency and ongoing viral replication) differ markedly and the contribution from IURMs relative to IRMs will continue to increase as a result of aging of the HIV-infected population, high smoking and lung cancer prevalence and a low prevalence of untreated HIV infection. These findings suggest the need for targeted preventive measures and evaluation of the cost−benefit of screening for IURMs in HIV-infected populations.
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| 45. |
- Middeldorp, Christel M., et al.
(författare)
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The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia : design, results and future prospects
- 2019
-
Ingår i: European Journal of Epidemiology. - : Springer Science and Business Media LLC. - 0393-2990 .- 1573-7284. ; 34:3, s. 279-300
-
Tidskriftsartikel (refereegranskat)abstract
- The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.
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| 46. |
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| 47. |
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| 48. |
- Mourikis, TP, et al.
(författare)
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Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma
- 2019
-
Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 3101-
-
Tidskriftsartikel (refereegranskat)abstract
- The identification of cancer-promoting genetic alterations is challenging particularly in highly unstable and heterogeneous cancers, such as esophageal adenocarcinoma (EAC). Here we describe a machine learning algorithm to identify cancer genes in individual patients considering all types of damaging alterations simultaneously. Analysing 261 EACs from the OCCAMS Consortium, we discover helper genes that, alongside well-known drivers, promote cancer. We confirm the robustness of our approach in 107 additional EACs. Unlike recurrent alterations of known drivers, these cancer helper genes are rare or patient-specific. However, they converge towards perturbations of well-known cancer processes. Recurrence of the same process perturbations, rather than individual genes, divides EACs into six clusters differing in their molecular and clinical features. Experimentally mimicking the alterations of predicted helper genes in cancer and pre-cancer cells validates their contribution to disease progression, while reverting their alterations reveals EAC acquired dependencies that can be exploited in therapy.
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| 49. |
- Cerutti, P. O., et al.
(författare)
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The socioeconomic and environmental impacts of wood energy value chains in Sub-Saharan Africa : A systematic map protocol
- 2015
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Ingår i: Environmental Evidence. - : Springer Science and Business Media LLC. - 2047-2382. ; 4:1
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Tidskriftsartikel (refereegranskat)abstract
- Background: The vast majority of households in Sub-Saharan Africa (SSA) depend on wood energy - comprising firewood and charcoal - for their daily energetic needs. Such consumption trends are expected to remain a common feature of SSA's wood energy production and supply chains, at least in the short- to medium-terms. Notwithstanding its importance, wood energy generally has low priority in SSA national policies. However, the use of wood energy is often considered a key driver of unsustainable management and negative environmental consequences in the humid and dry forests. To date, unsystematic assessments of the socio-economic and environmental consequences of wood energy use have underplayed its significance, thus further hampering policy debates. Therefore, a more balanced approach which considers both demand and supply dynamics is needed. This systematic map aims at providing a comprehensive approach to understanding the role and impacts of wood energy across all regions and aspects in SSA. Methods: The objective of this systematic map is to collate evidence from studies of environmental and socio-economic impacts of wood energy value chains, by considering both demand and supply within SSA. The map questions are framed using a Populations, Exposure, Comparators and Outcomes (PECO) approach. We name the supply and demand of wood energy as the "exposure," composed of wood energy production, harvesting, processing, and consumption. The populations of interest include both the actors involved in these activities and the forest sites where these activities occur. The comparator is defined as those cases where the same wood energy activities occur with i) available/accessible alternative energy sources, ii) regulatory frameworks that govern the sector and iii) alternative technologies for efficient use. The outcomes of interest encompass both socioeconomic and environmental impacts that can affect more than the populations named above. For instance, in addition to the direct socioeconomic impacts felt by participants in the wood energy value chain, forest dwellers may experience livelihood changes due to forest degradation caused by external harvesters. Moreover, intensified deforestation in one area may concurrently lead to forest regeneration in another.
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| 50. |
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