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Träfflista för sökning "WFRF:(Steele G.) srt2:(2000-2004)"

Sökning: WFRF:(Steele G.) > (2000-2004)

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1.
  • Pfaller, M.A., et al. (författare)
  • Twelve years of fluconazole in clinical practice : Global-trends in species distribution and fluconazole susceptibility of bloodstream isolates of Candida
  • 2004
  • Ingår i: Clinical Microbiology and Infection. - : Elsevier BV. - 1198-743X .- 1469-0691. ; 10:SUPPL. 1, s. 11-23
  • Tidskriftsartikel (refereegranskat)abstract
    • We determined the species distribution and in-vitro susceptibility of 6082 bloodstream infection (BSI) isolates of Candida spp. collected from 250 medical centres in 32 nations over a 10-year period from 1992 through 2001. The species included 3401 C. albicans, 984 C. glabrata, 796 C. parapsilosis, 585 C. tropicalis, 153 C. krusei, 67 C. lusitaniae, 48 C. guilliermondii, 10 C. famata, 10 C. kefyr, six C. pelliculosa, five C. rugosa, four C. lipolytica, three C. dubliniensis, three C. inconspicua, two C. sake and one isolate each of C. lambica, C. norvegensis and C. zeylanoides. Minimum inhibitory concentration determinations were made using the National Committee for Clinical Laboratory Standards reference broth microdilution method. Variation in the rank order and frequency of the different species of Candida was observed over time and by geographic area. The proportion of BSI due to C. albicans and C. glabrata increased and C. parapsilosis decreased over time in Canada, the USA and Europe. C. glabrata was an infrequent cause of BSI in Latin America and the Asia-Pacific region. Very little variation in fluconazole susceptibility was observed among isolates of C. albicans, C. tropicalis and C. parapsilosis. These species accounted for 78% of all BSI and remained highly susceptible (91-100% susceptible) to fluconazole from 1992 to 2001 irrespective of geographic origin. The prevalence of fluconazole resistance among C. glabrata isolates was variable both over time and among the various countries and regions. Resistance to fluconazole among C. glabrata isolates was greatest in the USA and varied by US census region (range 0-23%). These observations are generally encouraging relative to the sustained usefulness of fluconazole as a systemically active antifungal agent for the treatment of candida BSI. © 2004 Copyright by the European Society of Clinical Microbiology and Infectious Diseases.
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2.
  • Ahrens, J., et al. (författare)
  • Observation of high energy atmospheric neutrinos with the Antarctic muon and neutrino detector array
  • 2002
  • Ingår i: Physical Review D. - : American Physical Society. - 1550-7998 .- 1550-2368. ; 66:1, s. 120051-1200520
  • Tidskriftsartikel (refereegranskat)abstract
    • The Antarctic muon and neutrino detector array (AMANDA) began collecting data with ten strings in 1997. Results from the first year of operation are presented. Neutrinos coming through the Earth from the Northern Hemisphere are identified by secondary muons moving upward through the array. Cosmic rays in the atmosphere generate a background of downward moving muons, which are about 106 times more abundant than the upward moving muons. Over 130 days of exposure, we observed a total of about 300 neutrino events. In the same period, a background of 1.05 × 109 cosmic ray muon events was recorded. The observed neutrino flux is consistent with atmospheric neutrino predictions. Monte Carlo simulations indicate that 90% of these events lie in the energy range 66 GeV to 3.4 TeV. The observation of atmospheric neutrinos consistent with expectations establishes AMANDA-B10 as a working neutrino telescope.
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3.
  • Bai, X., et al. (författare)
  • Status of the Neutrino Telescope AMANDA : Monopoles and WIMPS
  • 2001
  • Ingår i: Dark Matter in Astro- and Particle Physics. - Berlin, Heidelberg : Springer. - 9783642626081 ; , s. 699-706
  • Konferensbidrag (refereegranskat)abstract
    • The neutrino telescope AMANDA has been set up at the geographical South Pole as first step to a neutrino telescope of the scale of one cubic kilometer, which is the canonical size for a detector sensitive to neutrinos from Active Galactic Nuclei (AGN), Gamma Ray Bursts (GRB) and Topological Defects (TD). The location and depth in which the detector is installed is given by the requirement to detect neutrinos by the Cherenkov light produced by their reaction products and to keep the background due to atmospheric muons as small as possible. However, a detector optimized for this purpose is also capable to detect the bright Cherenkov light from relativistic Monopoles and neutrino signals from regions with high gravitational potential, where WIMPS are accumulated and possibly annihilate. Both hypothetical particles might contribute to the amount of dark matter. Therefore here a report about the status of the experiment (autumn 2000) and about the status of the search for these particles with the AMANDA B10 sub-detector is given.
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4.
  • Edsjö, Joakim, et al. (författare)
  • WIMP searches with AMANDA-B10
  • 2001
  • Ingår i: The Identification Of Dark Matter. - : World Scientific. - 9789810246020 ; , s. 499-505
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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5.
  • Kowalski, Marek, et al. (författare)
  • Physics results from the AMANDA neutrino detector
  • 2001
  • Ingår i: Proceedings of Science. - 1824-8039. ; HEP2001
  • Tidskriftsartikel (refereegranskat)abstract
    • In the winter season of 2000, the AMANDA (Antarctic Muon And NeutrinoDetector Array) detector was completed to its nal state. We report on major physicsresults obtained from the AMANDA-B10 detector, as well as initial results of the fullAMANDA-II detector.
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6.
  • Ahrens, J., et al. (författare)
  • Initial results from AMANDA
  • 2001
  • Ingår i: 21st Rencontres de Moriond Workshop on Very High-Energy Phenomena in the Universe.
  • Konferensbidrag (refereegranskat)
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7.
  • Ahrens, J., et al. (författare)
  • Limits to the muon flux from WIMP annihilation in the center of the Earth with the AMANDA detector
  • 2002
  • Ingår i: Physical Review D. - : American Physical Society. - 1550-7998 .- 1550-2368. ; 66:3, s. 032006-
  • Tidskriftsartikel (refereegranskat)abstract
    • A search for nearly vertical up-going muon-neutrinos from neutralino annihilations in the center of the Earth has been performed with the AMANDA-B10 neutrino detector. The data collected in 130.1 days of live time in 1997, ∼10 9 events, have been analyzed for this search. No excess over the expected atmospheric neutrino background has been observed. An upper limit at 90% confidence level has been obtained on the annihilation rate of neutralinos in the center of the Earth, as well as the corresponding muon flux limit, both as a function of the neutralino mass in the range 100 GeV-5000 GeV. © 2002 The American Physical Society.
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8.
  • Ahrens, J., et al. (författare)
  • Results from AMANDA
  • 2001
  • Ingår i: Proceedings, 9th International Workshop, Venice, Italy, March 6-9, 2001. Vol. 1, 2. ; , s. 569-580
  • Konferensbidrag (refereegranskat)
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9.
  • Ahrens, J., et al. (författare)
  • Search for point sources of high-energy neutrinos with AMANDA
  • 2003
  • Ingår i: Astrophysical Journal Letters. - : Institute of Physics (IOP). - 2041-8205 .- 0004-637X .- 1538-4357. ; 583:2 I, s. 1040-1057
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper describes the search for astronomical sources of high-energy neutrinos using the AMANDA-B10 detector, an array of 302 photomultiplier tubes used for the detection of Cerenkov light from upward-traveling neutrino-induced muons, buried deep in ice at the South Pole. The absolute pointing accuracy and angular resolution were studied by using coincident events between the AMANDA detector and two independent telescopes on the surface, the GASP air Cerenkov telescope and the SPASE extensive air shower array. Using data collected from 1997 April to October (130.1 days of live time), a general survey of the northern hemisphere revealed no statistically significant excess of events from any direction. The sensitivity for a flux of muon neutrinos is based on the effective detection area for through-going muons. Averaged over the northern sky, the effective detection area exceeds 10,000 m2 for E μ ≈ 10 TeV. Neutrinos generated in the atmosphere by cosmic-ray interactions were used to verify the predicted performance of the detector. For a source with a differential energy spectrum proportional to Eν -2 and declination larger than +40°, we obtain E2(dNν/dE) ≤ 10-6 GeV cm-2 s-1 for an energy threshold of 10 GeV.
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10.
  • Ahrens, J., et al. (författare)
  • Search for supernova neutrino bursts with the AMANDA detector
  • 2001
  • Ingår i: Astroparticle physics. - : Elsevier. - 0927-6505 .- 1873-2852. ; 16:4, s. 345-359
  • Tidskriftsartikel (refereegranskat)abstract
    • The core collapse of a massive star in the Milky Way will produce a neutrino burst, intense enough to be detected by existing underground detectors. The AMANDA neutrino telescope located deep in the South Pole ice can detect MeV neutrinos by a collective rate increase in all photo-multipliers on top of dark noise. The main source of light comes from positrons produced in the CC reaction of anti-electron neutrinos on free protons ve + p → e+ + n. This paper describes the first supernova search performed on the full sets of data taken during 1997 and 1998 (215 days of live time) with 302 of the detector's optical modules. No candidate events resulted from this search. The performance of the detector is calculated, yielding a 70% coverage of the galaxy with one background fake per year with 90% efficiency for the detector configuration under study. An upper limit at the 90% c.l. on the rate of stellar collapses in the Milky Way is derived, yielding 4.3 events per year. A trigger algorithm is presented and its performance estimated. Possible improvements of the detector hardware are reviewed.
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11.
  • Andrés, E., et al. (författare)
  • Observation of high-energy neutrinos using Čerenkov detectors embedded deep in Antarctic ice
  • 2001
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 410:6827, s. 441-443
  • Tidskriftsartikel (refereegranskat)abstract
    • Neutrinos are elementary particles that carry no electric charge and have little mass. As they interact only weakly with other particles, they can penetrate enormous amounts of matter, and therefore have the potential to directly convey astrophysical information from the edge of the Universe and from deep inside the most cataclysmic high-energy regions. The neutrino's great penetrating power, however, also makes this particle difficult to detect. Underground detectors have observed low-energy neutrinos from the Sun and a nearby supernova2, as well as neutrinos generated in the Earth's atmosphere. But the very low fluxes of high-energy neutrinos from cosmic sources can be observed only by much larger, expandable detectors in, for example, deep water3,4 or ice5. Here we report the detection of upwardly propagating atmospheric neutrinos by the ice-based Antarctic muon and neutrino detector array (AMANDA). These results establish a technology with which to build a kilometre-scale neutrino observatory necessary for astrophysical observations1.
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12.
  • Andrés, E., et al. (författare)
  • Recent results from AMANDA
  • 2001
  • Ingår i: International Journal of Modern Physics A. - 0217-751X .- 1793-656X. ; 16:1C, s. 1013-1015
  • Tidskriftsartikel (refereegranskat)abstract
    • We present results based on data taken in 1997 with the 302-PMT Antarctic Muon and Neutrino Detector Array-B10 ("AMANDA-B10") array. Atmospheric neutrinos created in the northern hemisphere are observed indirectly through their charged current interactions which produce relativistic, Cherenkov-light-emitting upgoing muons in the South Pole ice cap. The reconstructed angular distribution of these events is in good agreement with expectation and demonstrates the viability of this ice-based device as a neutrino telescope.
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13.
  • Andres, E., et al. (författare)
  • Results from the AMANDA high energy neutrino detector
  • 2000
  • Ingår i: Nuclear physics B, Proceedings supplements. - : Elsevier. - 0920-5632 .- 1873-3832. ; 91:1-3, s. 423-430
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper briefly summarizes the search for astronomical sources of high-energy neutrinos using the AMANDA-B10 detector. The complete data set from 1997 was analyzed. For Eμ > 10 TeV, the detector exceeds 10,000 m2 in effective area between declinations of 25 and 90 degrees. Neutrinos generated in the atmosphere by cosmic ray interactions were used to verify the overall sensitivity of the detector. The absolute pointing accuracy and angular resolution has been confirmed by the analysis of coincident events between the SPASE air shower array and the AMANDA detector. Preliminary flux limits from point source candidates are presented. For declinations larger than +45 degrees, our results compare favorably to existing limits for sources in the Southern sky. We also present the current status of the searches for high energy neutrino emission from diffusely distributed sources, GRBs, and WIMPs from the center of the earth.
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14.
  • Andres, E., et al. (författare)
  • Selected recent results from AMANDA
  • 2001
  • Ingår i: ICHEP 2000. Proceedings of the 30th International Conference on High Energy Physics. - : World Scientific. ; , s. 965-968
  • Konferensbidrag (refereegranskat)abstract
    • We present a selection of results based on data taken in 1997 with the 302-PMT Antarctic Muon and Neutrino Detector Array-B10 ("AMANDA-B10") array. Atmospheric neutrinos created in the northern hemisphere are observed indirectly through their charged current interactions which produce relativistic, Cherenkov-light-emitting upgoing muons in the South Pole ice cap. The reconstructed angular distribution of these events is in good agreement with expectation and demonstrates the viability of this ice-based device as a neutrino telescope. Studies of nearly vertical upgoing muons limit the available parameter space for WIMP dark matter under the assumption that WIMPS are trapped in the earth's gravitational potential well and annihilate with one another near the earth's center.
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15.
  • Karle, A., et al. (författare)
  • Observation of high energy atmospheric neutrinos with AMANDA
  • 2000
  • Ingår i: AIP Conference Proceedings. - : American Institute of Physics (AIP). ; , s. 823-827
  • Konferensbidrag (refereegranskat)abstract
    • In 1997 the Antarctic Muon and Neutrino Detector Array (AMANDA) started operating with 10 strings. In an analysis of data taken during the first year of operation 188 atmospheric neutrino candidates were found. Their zenith angle distribution agrees with expectations based on Monte Carlo simulations. A preliminary upper limit is given on a diffuse flux of high energy neutrinos of astrophysical origin.
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16.
  • Niessen, Peter, et al. (författare)
  • Recent results from the amanda experiment
  • 2003
  • Ingår i: Proceedings of 38th Rencontres de Moriond on Electroweak Interactions and Unified Theories 15-22 Mar 2003. Les Arcs, France.
  • Konferensbidrag (refereegranskat)abstract
    • AMANDA (Antarctic Muon And Neutrino Detector Array) is a neutrino telescope built under the southern polar icecap and its scope is to explore the possibility to detect high energy cosmic neutrinos. This should generate insight into the powerful celestial objects where acceleration mechanisms can bring up to 10 20   eV. We describe the achievements and results from the AMANDA-B10 prototype and the preliminary results from the current AMANDA-II detector which show dramatic increase in sensitivity.
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17.
  • Ahrens, J., et al. (författare)
  • Calibration and survey of AMANDA with the SPASE detectors
  • 2004
  • Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier. - 0168-9002 .- 1872-9576. ; 522:3, s. 347-359
  • Tidskriftsartikel (refereegranskat)abstract
    • We report on the analysis of air showers observed in coincidence by the Antarctic Muon and Neutrino detector array (AMANDA-B10) and the South Pole Air Shower Experiment (SPASE-1 and SPASE-2). We discuss the use of coincident events for calibration and survey of the deep AMANDA detector as well as the response of AMANDA to muon bundles. This analysis uses data taken during 1997 when both SPASE-1 and SPASE-2 were in operation to provide a stereo view of AMANDA. © 2003 Elsevier B.V. All rights reserved.
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18.
  • Ahrens, J., et al. (författare)
  • Limits on diffuse fluxes of high energy extraterrestrial neutrinos with the AMANDA-B10 detector
  • 2003
  • Ingår i: Physical Review Letters. - : American Physical Society. - 0031-9007 .- 1079-7114. ; 90:25, s. 2511011-2511015
  • Tidskriftsartikel (refereegranskat)abstract
    • A report on the limits, which could be placed on diffuse fluxes of high energy extraterrestrial neutrinos, was presented. The incorporation of neutrino oscillations was necessary for interpreting the limits in terms of the flux from a cosmological distributions of sources. The energetic accelerated environments were presented as the sources of high energy extraterrestrial neutrinos.
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19.
  • Ahrens, J., et al. (författare)
  • Measurement of the cosmic ray composition at the knee with the SPASE-2/AMANDA-B10 detectors
  • 2004
  • Ingår i: Astroparticle physics. - : Elsevier. - 0927-6505 .- 1873-2852. ; 21:6, s. 565-581
  • Tidskriftsartikel (refereegranskat)abstract
    • The mass composition of high-energy cosmic rays at energies above 1015 eV can provide crucial information for the understanding of their origin. Air showers were measured simultaneously with the SPASE-2 air shower array and the AMANDA-B10 Cherenkov telescope at the South Pole. This combination has the advantage to sample almost all high-energy shower muons and is thus a new approach to the determination of the cosmic ray composition. The change in the cosmic ray mass composition was measured versus existing data from direct measurements at low energies. Our data show an increase of the mean log atomic mass 〈lnA〉 by about 0.8 between 500 TeV and 5 PeV. This trend of an increasing mass through the "knee" region is robust against a variety of systematic effects. © 2004 Elsevier B.V. All rights reserved.
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20.
  • Ahrens, J., et al. (författare)
  • Physics and operation of the AMANDA-II high energy neutrino telescope
  • 2002
  • Ingår i: Proceedings of the SPIE - The International Society for Optical Engineering 2003. - : Institution of Electrical Engineers (IEE). ; , s. 79-91
  • Konferensbidrag (refereegranskat)abstract
    • This paper briefly describes the principle of operation and science goals of the AMANDA high energy neutrino telescope located at the South Pole, Antarctica. Results from an earlier phase of the telescope, called AMANDA-B10, demonstrate both reliable operation and the broad astrophysical reach of this device, which includes searches for a variety of sources of ultrahigh energy neutrinos: generic point sources, Gamma-Ray Bursts and diffuse sources. The predicted sensitivity and angular resolution of the telescope were confirmed by studies of atmospheric muon and neutrino backgrounds. We also report on the status of the analysis from AMANDA-II, a larger version with far greater capabilities. At this stage of analysis, details of the ice properties and other systematic uncertainties of the AMANDA-II telescope are under study, but we have made progress toward critical science objectives. In particular, we focus on the search for continuous emission from astrophysical point sources and the search for correlated neutrino emission from Gamma Ray Bursts detected by BATSE before decommissioning in May 2000. During the next two years, we expect to exploit the full potential of AMANDA-II with the installation of a new data acquisition system that records full waveforms from the in-ice optical sensors.
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21.
  • Ahrens, J., et al. (författare)
  • Results from the AMANDA telescope
  • 2003
  • Ingår i: Nuclear Physics A. - : Elsevier. - 0375-9474 .- 1873-1554. ; 721, s. C545-C548
  • Tidskriftsartikel (refereegranskat)abstract
    • We present results from the AMANDA high energy neutrino telescope located at the South Pole. They include measurements of the atmospheric neutrino flux, search for UHE point sources, and diffuse sources producing electromagnetic/hadronic showers at the detector or close to it.
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22.
  • Ahrens, J., et al. (författare)
  • Search for Extraterrestrial Point Sources of Neutrinos with AMANDA-II
  • 2004
  • Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 92:7, s. 711021-711025
  • Tidskriftsartikel (refereegranskat)abstract
    • The results of a search for point sources of high energy neutrinos in the northern hemisphere were presented using AMANDA-II data collected in the year 2000. The results included the flux limits on several active-galactic-nuclei blazars, microquasars, magnetars, and other candidate neutrino sources. A search for excesses above a random background of cosmic ray induced atmospheric neutrinos and misreconstructed downgoing cosmic-rays muons, which revealed no statistically significant neutrino point sources was also presented. It was shown that AMANDA-II had achieved the sensitivity required to probe known TeV γ-ray sources such as the blazar Markarian 501 in its 1997 flaring state at a level where neutrino and γ-ray fluxes were equal.
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23.
  • Ahrens, J., et al. (författare)
  • Search for neutrino-induced cascades with the AMANDA detector
  • 2003
  • Ingår i: Physical Review D. - : American Physical Society (APS). - 1550-7998 .- 1550-2368. ; 67:1, s. 012003-
  • Tidskriftsartikel (refereegranskat)abstract
    • We report on a search for electromagnetic and/or hadronic showers (cascades) induced by a diffuse flux of neutrinos with energies between 5 TeV and 300 TeV from extraterrestrial sources. Cascades may be produced by matter interactions of all flavors of neutrinos, and contained cascades have better energy resolution and afford better background rejection than throughgoing νμ-induced muons. Data taken in 1997 with the AMANDA detector were searched for events with a high-energy cascadelike signature. The observed events are consistent with expected backgrounds from atmospheric neutrinos and catastrophic energy losses from atmospheric muons. Effective volumes for all flavors of neutrinos, which allow the calculation of limits for any neutrino flux model, are presented. The limit on cascades from a diffuse flux of νe+ νμ + ντ+ ν̄e + ν̄μ+ ν̄τ is E2(dΦ/dE)<9.8×10-6 GeV cm-2 s-1 sr-1, assuming a neutrino flavor flux ratio of 1:1:1 at the detector. The limit on cascades from a diffuse flux of νe+ν̄e is E2(dΦ/dE)<6. 5×10-6 GeV cm-2 s-1 sr-1, independent of the assumed neutrino flavor flux ratio. © 2003 The American Physical Society.
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24.
  • Wiebusch, C., et al. (författare)
  • Results from AMANDA
  • 2002
  • Ingår i: Modern Physics Letters A. - : Institution of Electrical Engineers (IEE). - 0217-7323 .- 1793-6632. ; 17:31, s. 2019-2037
  • Tidskriftsartikel (refereegranskat)abstract
    • The Antarctic Muon and Neutrino Detector Array (AMANDA) is a high-energy neutrino telescope operating at the geographic South Pole. It is a lattice of photomultiplier tubes buried deep in the polar ice. The primary goal of this detector is to discover astrophysical sources of high energy neutrinos. We describe the detector methods of operation and present results from the AMANDA-B10 prototype. We demonstrate the improved sensitivity of the current AMANDA-II detector. We conclude with an outlook to the envisioned sensitivity of the future IceCube detector.
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25.
  • Ahrens, J., et al. (författare)
  • Results from the Antarctic muon and nuetrino detector array
  • 2003
  • Ingår i: Nuclear physics B, Proceedings supplements. - : Elsevier. - 0920-5632 .- 1873-3832. ; 118, s. 371-379
  • Tidskriftsartikel (refereegranskat)abstract
    • We show new results from both the older and newer incarnations of AMANDA (AMANDA-B10 and AMANDA-II, respectively). These results demonstrate that AMANDA is a functioning, multipurpose detector with significant physics and astrophysics reach. They include a new higher-statistics measurement of the atmospheric muon neutrino flux and preliminary results from searches for a variety of sources of ultrahigh energy neutrinos: generic point sources, gamma-ray bursters and diffuse sources producing muons in the detector, and diffuse sources producing electromagnetic or hadronic showers in or near the detector.
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26.
  • Pinniger, G J, et al. (författare)
  • H-reflex modulation during passive lengthening and shortening of the human triceps surae.
  • 2001
  • Ingår i: Journal of Physiology. - : Wiley. - 0022-3751 .- 1469-7793. ; 534:Pt 3, s. 913-23
  • Tidskriftsartikel (refereegranskat)abstract
    • 1. The present study investigated the effects of lengthening and shortening actions on H-reflex amplitude. H-reflexes were evoked in the soleus (SOL) and medial gastrocnemius (MG) of human subjects during passive isometric, lengthening and shortening actions performed at angular velocities of 0, +/-2, +/-5 and +/-15 deg s(-1). 2. H-reflex amplitudes in both SOL and MG were significantly depressed during passive lengthening actions and facilitated during passive shortening actions, when compared with the isometric H-reflex amplitude. 3. Four experiments were performed in which the latencies from the onset of movement to delivery of the stimulus were altered. Passive H-reflex modulation during lengthening actions was found to begin at latencies of less than 60 ms suggesting that this inhibition was due to peripheral and/or spinal mechanisms. 4. It is postulated that the H-reflex modulation seen in the present study is related to the tonic discharge of muscle spindle afferents and the consequent effects of transmission within the Ia pathway. Inhibition of the H-reflex at less than 60 ms after the onset of muscle lengthening may be attributed to several mechanisms, which cannot be distinguished using the current protocol. These may include the inability to evoke volleys in Ia fibres that are refractory following muscle spindle discharge during rapid muscle lengthening, a reduced probability of transmitter release from the presynaptic terminal (homosynaptic post-activation depression) and presynaptic inhibition of Ia afferents from plantar flexor agonists. Short latency facilitation of the H-reflex may be attributed to temporal summation of excitatory postsynaptic potentials arising from muscle spindle afferents during rapid muscle lengthening. At longer latencies, presynaptic inhibition of Ia afferents cannot be excluded as a potential inhibitory mechanism.
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27.
  • Pinniger, G J, et al. (författare)
  • Tension regulation during lengthening and shortening actions of the human soleus muscle.
  • 2000
  • Ingår i: European Journal of Applied Physiology. - : Springer Science and Business Media LLC. - 1439-6319 .- 1439-6327 .- 0301-5548. ; 81:5, s. 375-83
  • Tidskriftsartikel (refereegranskat)abstract
    • In the present study we investigated tension regulation in the human soleus (SOL) muscle during controlled lengthening and shortening actions. Eleven subjects performed plantar flexor efforts on an ankle torque motor through 30 degrees of ankle displacement (75 degrees -105 degrees internal ankle angle) at lengthening and shortening velocities of 5, 15 and 30 degrees. S(-1). To isolate the SOL from the remainder of the triceps surae, the subject's knee was flexed to 60 degrees during all trials. Voluntary plantar flexor efforts were performed under two test conditions: (1) maximal voluntary activation (MVA) of the SOL, and (2) constant submaximal voluntary activation (SVA) of the SOL. SVA trials were performed with direct visual feedback of the SOL electromyogram (EMG) at a level resulting in a torque output of 30% of isometric maximum. Angle-specific (90 degrees ankle angle) torque and EMG of the SOL, medial gastrocnemius (MG) and tibialis anterior (TA) were recorded. In seven subjects from the initial group, the test protocol was repeated under submaximal percutaneous electrical activation (SEA) of SOL (to 30% isometric maximal effort). Lengthening torques were significantly greater than shortening torques in all test conditions. Lengthening torques in MVA and SVA were independent of velocity and remained at the isometric level, whereas SEA torques were greater than isometric torques and increased at higher lengthening velocities. Shortening torques were lower than the isometric level for all conditions. However, whereas SVA and SEA torques decreased at higher velocities of shortening, MVA torques were independent of velocity. These results indicate velocity- and activation-type-specific tension regulation in the human SOL muscle.
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