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Estimates of epilepsy prevalence, psychiatric co-morbidity and cost

Christensen, Jakob (author)
Department of Neurology, Aarhus University Hospital, Aarhus, Denmark; The National Center for Register-based Research, Aarhus University, Aarhus, Denmark; Affiliated Partner of the European Reference Network, EpiCARE, Italy
Dreier, Julie Werenberg (author)
The National Center for Register-based Research, Aarhus University, Aarhus, Denmark; Centre for Integrated Register-based Research, CIRRAU, Aarhus University, Aarhus, Denmark
Sun, Yuelian (author)
Department of Neurology, Aarhus University Hospital, Aarhus, Denmark; The National Center for Register-based Research, Aarhus University, Aarhus, Denmark
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Linehan, Christine (author)
UCD Centre for Disability Studies, University College Dublin, Ireland
Tomson, Torbjörn (author)
Karolinska Institutet
Marson, Anthony (author)
Affiliated Partner of the European Reference Network, EpiCARE, Italy; Institute of Translational Medicine, University of Liverpool, United Kingdom
Forsgren, Lars (author)
Umeå universitet,Neurovetenskaper
Granbichler, Claudia A. (author)
Affiliated Partner of the European Reference Network, EpiCARE, Italy; Department of Neurology, Christian Doppler Klinik, Paracelsus Medical University and Centre for Cognitive Neuroscience, Salzburg, Austria; Department of Neurology, Chaim Sheba Medical Center, Ramat Gan, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Trinka, Eugen (author)
Affiliated Partner of the European Reference Network, EpiCARE, Italy; Department of Neurology, Christian Doppler Klinik, Paracelsus Medical University and Centre for Cognitive Neuroscience, Salzburg, Austria; Department of Public Health, Health Services Research and Health Technology Assessment, UMIT – University for Health Sciences, Medical Informatics and Technology, Hall in Tirol, Austria
Illiescu, Catrinel (author)
Clinical Neurosciences Department, “Carol Davila”, University of Medicine and Pharmacy, Bucharest, Romania; Pediatric Neurology Clinic, Expertise Centre for Rare Diseases in Pediatric Neurology, “Prof Dr Alexandru Obregia” Clinical Hospital, Bucharest, Romania; Member of the European Reference Network, EpiCARE
Malmgren, Kristina, 1952 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
Kjellberg, Jakob (author)
VIVE – The Danish Center for Social Science Research, Copenhagen, Denmark
Ibsen, Rikke (author)
i2minds, Aarhus, Denmark
Jennum, Poul Jorgen (author)
Danish Center of Sleep Medicine, Rigshospitalet (Copenhagen University Hospital), Denmark
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 (creator_code:org_t)
Elsevier, 2023
2023
English.
In: Seizure. - : Elsevier. - 1059-1311 .- 1532-2688. ; 107, s. 162-171
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Purpose: This study estimated epilepsy prevalence, psychiatric co-morbidity and annual costs associated with epilepsy.Methods: We used Danish national health registers to identify persons diagnosed with epilepsy and psychiatric disorders, and persons using antiseizure medication and persons using drugs for psychiatric disorders. We calculated the prevalence of epilepsy and co-morbid psychiatric disorders in Denmark on December 31, 2016, using information on epilepsy and psychiatric disorders based on combinations of hospital contacts and use of antiseizure and psychoactive medication. Further, direct and indirect annual costs associated with epilepsy were calculated using individual-level data from a range of socioeconomic registers.Results: There were 5,044,367 persons alive and living in Denmark on December 31, 2016, including 33,628 persons with at least one hospital contact with epilepsy in the previous five years (epilepsy prevalence 0.67% (0.69% males; 0.65% females)). Among these persons with epilepsy, we identified 12,562 (37.4%) persons with a psychiatric disorder or use of drugs used for psychiatric disorders as compared with 801,052 (15.9%) persons in the general population. The estimated total annual individual net costs associated with epilepsy was €30,683. Compared with prevalence estimates on December 31, 2006, the prevalence of epilepsy on December 31, 2016, was slightly higher in the older population and slightly lower in childrenConclusions: Population estimates from national registers provide epilepsy prevalence estimates of approximately 0.6–0.7% - similar to previous reviews of epilepsy prevalence. In addition, the national sample allowed idenitfication of high prevalence of psychiatric disorders and high societal costs associated with epielspy.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Neurosciences (hsv//eng)

Keyword

Cost
Epidemiology
Prevalence
Psychiatric co-morbidity
Cost
Epidemiology
Prevalence
Psychiatric co-morbidity

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ref (subject category)
art (subject category)

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