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Search: WFRF:(Thornberg Charlotte) > (2015-2019)

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1.
  • Ceberg, Sofie, et al. (author)
  • Surface guided radiotherapy decreases the uncertainty in breast cancer patient setup
  • 2018
  • Conference paper (peer-reviewed)abstract
    • (Sunday, 7/29/2018) 3:00 PM - 6:00 PMRoom: Exhibit HallPurpose: The aim was to investigate if the setup of breast cancer patients could be improved using surface guided radiotherapy, compared to the conventional method using lasers and skin markings.Methods: Forty-seven patients, who received tangential or locoregional adjuvant radiotherapy, were positioned using a surface-based setup (SBS). Thirty-eight patients were positioned using the conventional laser-based setup (LBS). For the patient group positioned using a SBS, correction for posture was performed under guidance of a color map projected onto the patients' skin in real time. The surface tolerance for the color map was 5 mm. For both setup techniques the deviation of the breast position was measured using verification images. In total, 897 images were analysed. The frequency distributions of the deviations were analysed.Results: The result showed a significant improvement in the interfractional variation of the setup deviation for SBS compared to the LBS (pConclusion: Conventional laser-based setup can be replaced by surface-based setup, both for tangential and locoregional breast cancer treatments.
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2.
  • Jönsson, Mattias, et al. (author)
  • Technical evaluation of a laser-based optical surface scanning system for prospective and retrospective breathing adapted computed tomography.
  • 2015
  • In: Acta Oncologica. - 1651-226X. ; 54:2, s. 261-265
  • Journal article (peer-reviewed)abstract
    • Background. For breathing adapted radiotherapy, the same motion monitoring system can be used for imaging and triggering of the accelerator. Purpose. To evaluate a new technique for prospective gated computed tomography (CT) and four-dimensional CT (4DCT) using a laser based surface scanning system (Sentinel(™), C-RAD, Uppsala, Sweden). The system was compared to the AZ-733V respiratory gating system (Anzai Medical, Tokyo, Japan) and the Real-Time Position Management System (RPM(™)) (Varian Medical Systems, Palo Alto, CA, USA). Material and methods. Temporal accuracy was evaluated using a moving phantom programmed to move a platform along trajectories following a sin(6)(ωt) function with amplitudes from 6 to 20 mm and periods from 2 to 5 s during 120 s while the motion was recorded. The recorded data was Fourier transformed and the peak area at the fundamental and harmonic frequencies compared to data generated using the same sinusoidal function. For verification of the 4DCT reconstruction process, the phantom was programmed to move along a sinusoidal trajectory. Ten phase series were reconstructed. The distance from the couch to the platform was measured in each image. By fitting the function sin(ωt-ϕ) to the values measured in the images corresponding to each slice, the phase of each image was verified. Results and conclusion. In the recorded data, the peak area at the fundamental frequency covered on average 104 ± 4%, 102 ± 4% and 91 ± 27% of the peak area in the generated data for the Sentinel(™), RPM(™) and AZ-733V systems, respectively. All systems managed to resolve both harmonic frequencies. The second experiment showed that all images were sorted into the correct series using breathing data recorded by each system. The systems generated very similar results, however, it is preferable to use the same system both for imaging and treatment.
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3.
  • Kügele, Malin, et al. (author)
  • Surface guided radiotherapy (SGRT) improves breast cancer patient setup accuracy
  • 2019
  • In: Journal of Applied Clinical Medical Physics. - : Wiley. - 1526-9914. ; , s. 61-68
  • Journal article (peer-reviewed)abstract
    • Purpose: The purpose of the study was to investigate if surface guided radiotherapy (SGRT) can decrease setup deviations for tangential and locoregional breast cancer patients compared to conventional laser-based setup (LBS). Materials and Methods: Both tangential (63 patients) and locoregional (76 patients) breast cancer patients were enrolled in this study. For LBS, the patients were positioned by aligning skin markers to the room lasers. For the surface based setup (SBS), an optical surface scanning system was used for daily setup using both single and three camera systems. To compare the two setup methods, the patient position was evaluated using verification imaging (field images or orthogonal images). Results: For both tangential and locoregional treatments, SBS decreased the setup deviation significantly compared to LBS (P < 0.01). For patients receiving tangential treatment, 95% of the treatment sessions were within the clinical tolerance of ≤ 4 mm in any direction (lateral, longitudinal or vertical) using SBS, compared to 84% for LBS. Corresponding values for patients receiving locoregional treatment were 70% and 54% for SBS and LBS, respectively. No significant difference was observed comparing the setup result using a single camera system or a three camera system. Conclusions: Conventional laser-based setup can with advantage be replaced by surface based setup. Daily SGRT improves patient setup without additional imaging dose to breast cancer patients regardless if a single or three camera system was used.
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