| 1. |
- Korayem, A M, et al.
(författare)
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A Drosophila salivary gland mucin is also expressed in immune tissues : evidence for a function in coagulation and the entrapment of bacteria
- 2004
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Ingår i: Insect Biochemistry and Molecular Biology. - : Elsevier BV. - 0965-1748 .- 1879-0240. ; 34:12, s. 1297-1304
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Tidskriftsartikel (refereegranskat)abstract
- Our studies on the developmental regulation of glycosylation in Drosophila melanogaster led us to identify and characterize gp 150, an ecdysone-regulated mucin that is found in hemocytes, the gut (peritrophic membrane) and in the salivary glands. We are particularly interested in mucin immune functions and found that gp 150 is released from larval hemocytes, becomes part of the clot and participates in the entrapment of bacteria. By RT-PCR and RNAi experiments, we identified gp 150 as the previously described 171-7, an ecdysone-induced salivary glue protein. We discuss the evolutionary and biochemical implications of the dual use of salivary proteins for immune functions in insects. Further molecular characterization of such shared proteins may enable a better understanding of the properties of proteins involved in containment and elimination of microbes, as well as hemostasis and wound repair.
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| 2. |
- Ueda, K, et al.
(författare)
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Nuclear motion and symmetry breaking of the B 1s-excited BF3 molecule
- 2003
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Ingår i: Chemical Physics. - 0301-0104. ; 289:1, s. 135-147
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Tidskriftsartikel (refereegranskat)abstract
- Out-of-plane nuclear motion stimulated in the core-excited state and symmetry breaking due to this nuclear motion have been investigated for B Is excitation in the BF3 molecule by a combination of three different experimental methods: angle-resolved ion-yield spectroscopy, vibrationally resolved resonant Auger electron spectroscopy and quadruple-ion coincidence momentum-imaging technique. (C) 2002 Elsevier Science B.V. All rights reserved.
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| 3. |
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| 4. |
- Feifel, R, et al.
(författare)
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Probing doubly excited ionic states of N-2(+) via a triple excitation above the N 1s threshold in the N-2 molecule
- 2003
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Ingår i: Physical Review A (Atomic, Molecular and Optical Physics). - 1050-2947. ; 67:3: 032504
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Tidskriftsartikel (refereegranskat)abstract
- Angle-resolved resonant Auger-electron spectroscopy has been carried out on the nitrogen molecule at selected photon energies around 419 eV, where a 1s core electron and two valence electrons are promoted into the lowest unoccupied molecular orbital 1pi(g). Significant enhancement of a specific band, which cannot be disentangled in direct photoionization, is observed at a binding energy of 37.6 eV, with a value of the anisotropy parameter beta much smaller than 2. We assign this new band to the transition to a doubly excited cationic state of N-2, in which two of the excited valence electrons remain in the 1pi(g) orbital, proposing a "double spectator" type decay mechanism. This observation shows how to preferentially probe multiply excited configurations of cations using multiple resonant excitation.
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| 5. |
- Kitajima, M., et al.
(författare)
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Doppler effect in resonant photoemission from SF6 : Correlation between doppler profile and auger emission anisotropy
- 2003
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 91:21
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Tidskriftsartikel (refereegranskat)abstract
- Fragmentation of the SF6 molecule upon F 1s excitation has been studied by resonant photoemission. The F atomiclike Auger line exhibits the characteristic Doppler profile that depends on the direction of the photoelectron momentum relative to the polarization vector of the radiation as well as on the photon energy. The measured Doppler profiles are analyzed by the model simulation that takes account of the anisotropy of the Auger emission in the molecular frame. The Auger anisotropy extracted from the data decreases with an increase in the F-SF5 internuclear distance.
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| 6. |
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| 7. |
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| 8. |
- Mineta, H, et al.
(författare)
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Low expression of fragile histidine triad gene correlates with high proliferation in head and neck squamous cell carcinoma
- 2003
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Ingår i: Oral Oncology. - 1879-0593. ; 39:1, s. 56-63
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Tidskriftsartikel (refereegranskat)abstract
- Frequent loss of heterozygosity in head and neck squamous cell carcinoma (HNSCC) has been found in several chromosomal regions such as 3p, 9p, 11q, 13q and 17p. Fragile histidine triad (FHIT) gene is located at 3p14.2 encompassing a common fragile site, and is identified as a tumor suppressor gene. We examined 57 patients with HNSCC using immunohistochemistry, western blot, and reverse transcriptase polymerase chain reaction. The association between FHIT expression and clinicopathologic characteristics including p53 and Ki-67 expressions was analyzed. Immunohistochemical analysis revealed 30 patients (53%) of low FHIT expression and 27 patients (47%) of high FHIT expression. Low FHIT expression significantly correlated with high Ki-67 expression, indicating that tumor cells with low FHIT expression can proliferate aggressively. No correlation was found between FHIT expression and clinical characteristics including age, gender, tumor size, lymph node status, stage grouping, histologic grade, p53 expression, and prognosis. FHIT alteration may play an important role in cancer development of HNSCC, however it did not contribute to the prognosis. (C) 2002 Elsevier Science Ltd. All rights reserved.
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| 9. |
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| 10. |
- R. Feifel, K. Ueda, A. De Fanis, K. Okada, S. Tanimoto, T. Furuta, H. Shindo, M. Kitajima, H. Tanaka, O. Björneholm, L. Karlsson, S. Svensson and S. L. Sorensen
(författare)
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Probing doubly excited ionic states of N2+ via a triple excitation above the N1s threshold in the N2 moecule
- 2003
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Ingår i: Phys. Rev.. ; A:67, s. 32504-
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Tidskriftsartikel (refereegranskat)
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| 11. |
- Ristinmaa Sörensen, Stacey, et al.
(författare)
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Application of an atomic relaxation model for the interpretation of O1s to Rydberg excited Auger electron spectra of molecular oxygen
- 2004
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Ingår i: Chemical Physics Letters. - : Elsevier BV. - 0009-2614. ; 398:1-3, s. 168-174
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Tidskriftsartikel (refereegranskat)abstract
- Resonant and normal Auger electron spectra associated with an O1s initial vacancy of the O-2 molecule have been recorded using photon energies of 541.80, 541.97 and 650 eV. The resonant Auger spectra obtained at 541.80 and 541.97 eV are interpreted as composed essentially of two characteristic parts, one between 10 and 35 eV binding energy reminiscent to direct photoionisation, and another, above 35 eV, associated primarily with spectator decay of the intermediate core-hole state. The spectra above 35 eV owe some similarity to the ordinary Auger electron spectrum recorded at 650 eV, and an interpretation is made in terms of Rydberg series in the cation converging towards the dicationic ionisation limits. The interpretation is based on a relaxation model introduced earlier for atomic resonant Auger spectra. The assignments of the resonant spectra assume that the relevant intermediate neutral states at 541.80 and 541.97 eV governing the Auger decay are essentially the v = 0 and 1 vibrational components of the (O1s) ((4)Sigma(u)(-)) 4psigma Rydberg state. Arguments for this interpretation are given.
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| 12. |
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| 13. |
- Ueda, K, et al.
(författare)
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Anisotropic ultrafast dissociation probed by the Doppler effect in resonant photoemission from CF4
- 2003
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Ingår i: Physical Review Letters. - 1079-7114. ; 90:23: 233006
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Tidskriftsartikel (refereegranskat)abstract
- The resonant Auger spectrum from the decay of F 1s-excited CF4 is measured. Several lines exhibit a nondispersive kinetic energy as the exciting photon energy is tuned through the resonance region. The F 1s(-1) atomiclike Auger line is split into two components due to the emission of Auger electrons by a fragment in motion, when electron emission is observed along the polarization vector of the light. This Doppler splitting is direct evidence that the core excitation leads to T-d-->C-3v symmetry lowering, by elongation of a specific C-F bond preferentially aligned along the polarization vector of the incident photon.
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