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| 2. |
- Pfrommer, H., et al.
(författare)
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Experimental Demonstration of Full-Duplex DOCSIS Signal Transmissions over a Wireline/Wireless-Fibre Access Network
- 2006
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Ingår i: 2006 International Topical Meeting on Microwaves Photonics. ; , s. 89-92
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Konferensbidrag (refereegranskat)abstract
- A fibre-radio access network architecture for simultaneous wireline and wireless transmissions of data over cable service interface specification (DOCSIS) signals is presented. An all-optical harmonic up-conversion technique using a dual-drive Mach-Zehnder modulator (DD-MZM) is employed at the central station while an InGaAsP/InGaAsP multiple quantum well (MQW) asymmetric Fabry-Perot modulator/detector (AFPM) functions as a single optical/electrical transducer performing optical intensity modulation and photodetection simultaneously at the base station. Full-duplex operation is demonstrated for both access types in an indoor laboratory environment as well as in a small-scale outdoor field trial
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| 3. |
- Pfrommer, H., et al.
(författare)
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Full-duplex DOCSIS/wirelessDOCSIS fiber-radio network employing packaged AFPM-based base-stations
- 2006
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Ingår i: IEEE Photonics Technology Letters. - : Institute of Electrical and Electronics Engineers (IEEE). - 1041-1135 .- 1941-0174. ; 18:04-jan, s. 406-408
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Tidskriftsartikel (refereegranskat)abstract
- The simultaneous wireline (600 MHz) and wireless (5.5 GHz) transmission of data over cable service interface specification (DOCSIS) signals in a hybrid fiber-radio access network is presented. The DOCSIS signal wireless replica is generated by means of an optical harmonic up-conversion technique based on a dual-drive Mach-Zehnder modulator. The optical signal is fed to a base station (BS) where a packaged asymmetric Fabry-Perot modulator/detector acts simultaneously as a photodetector and an optical modulator. At the BS, the DOCSIS signals can be fed either to a wireline or a wireless access network, in a highly flexible approach. Full-duplex operation has been demonstrated for both access types, including indoor wireless transmission.
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| 4. |
- Karlsson, Hasse, 1943, et al.
(författare)
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High-throughput and high-sensitivity nano-LC/MS and MS/MS for O-glycan profiling.
- 2009
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Ingår i: Methods in molecular biology (Clifton, N.J.). - Totowa, NJ : Humana Press. - 1064-3745. ; 534, s. 117-31
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Tidskriftsartikel (refereegranskat)abstract
- Sensitive and fast methods for the profiling of biologically important molecules are highly demanded. Mucins are densely O-glycosylated glycoproteins found at mucosal surfaces and are of great medical interest. Here we describe sensitive methods for the analysis of O-glycans from mucins using gel electrophoresis, and chromatography by nanoLC on graphite columns and structural analysis by electrospray mass spectrometry on a linear trap mass spectrometer.
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| 5. |
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| 6. |
- Medeiros, Marcelo C., et al.
(författare)
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Linear models, smooth transition autoregressions, and neural networks for forecasting macroeconomic time series : a re-examination
- 2005
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Ingår i: International Journal of Forecasting. - : Elsevier. - 1872-8200 .- 0169-2070. ; 21:4, s. 755-774
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Tidskriftsartikel (refereegranskat)abstract
- In this paper, we examine the forecast accuracy of linear autoregressive, smooth transition autoregressive (STAR), and neural network (NN) time series models for 47 monthly macroeconomic variables of the G7 economies. Unlike previous studies that typically consider multiple but fixed model specifications, we use a single but dynamic specification for each model class. The point forecast results indicate that the STAR model generally outperforms linear autoregressive models. It also improves upon several fixed STAR models, demonstrating that careful specification of nonlinear time series models is of crucial importance. The results for neural network models are mixed in the sense that at long forecast horizons, an NN model obtained using Bayesian regularization produces more accurate forecasts than a corresponding model specified using the specific-to-general approach. Reasons for this outcome are discussed.
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| 7. |
- Sihlbom, Carina, 1973, et al.
(författare)
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Localization of O-glycans in MUC1 glycoproteins using electron-capture dissociation fragmentation mass spectrometry.
- 2009
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Ingår i: Glycobiology. - : Oxford University Press (OUP). - 1460-2423 .- 0959-6658. ; 19:4, s. 375-81
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Tidskriftsartikel (refereegranskat)abstract
- MUC1 is a mucin glycoprotein containing multiple tandem repeats of 20 amino acids, with five serines and threonines that can be O-glycosylated. Here, we investigated the O-glycosylation site occupancy in MUC1 glycoproteins produced in two mutant CHO cell lines, Lec3.2.8.1 and ldlD. We found that the average site occupancy was higher in MUC1 from Lec3.2.8.1 than from ldlD and that the occupancy increased with the number of tandem repeats in the protein and also depended on the culture conditions used for production. Moreover, we describe the successful use of electron-capture dissociation (ECD) fragmentation, coupled to online liquid chromatography mass spectrometry, to determine the glycosylation of individual sites in recombinant MUC1 proteins with 16 tandem repeats. We analyzed MUC1 tandem repeat peptides with 1-5 GalNAc residues by ECD fragmentation and found that the first site to be glycosylated was either Ser-5 or Thr-6, with the addition of a second GalNAc at Thr-14. For peptides with three GalNAc residues, several different variants of glycopeptides were found, indicating a heterogeneous order of glycosylation at this stage. In contrast, only one variant was found for peptides with four GalNAc residues, where Thr-19 in the PDTR motif was left unglycosylated, indicating that this site is glycosylated last. The results gave novel insight into the order of GalNAc substitution in MUC1 in vivo.
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