| 1. |
- Haghighi, Mona, et al.
(författare)
-
A Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study
- 2016
-
Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 6
-
Tidskriftsartikel (refereegranskat)abstract
- Regression models are extensively used in many epidemiological studies to understand the linkage between specific outcomes of interest and their risk factors. However, regression models in general examine the average effects of the risk factors and ignore subgroups with different risk profiles. As a result, interventions are often geared towards the average member of the population, without consideration of the special health needs of different subgroups within the population. This paper demonstrates the value of using rule-based analysis methods that can identify subgroups with heterogeneous risk profiles in a population without imposing assumptions on the subgroups or method. The rules define the risk pattern of subsets of individuals by not only considering the interactions between the risk factors but also their ranges. We compared the rule-based analysis results with the results from a logistic regression model in The Environmental Determinants of Diabetes in the Young (TEDDY) study. Both methods detected a similar suite of risk factors, but the rule-based analysis was superior at detecting multiple interactions between the risk factors that characterize the subgroups. A further investigation of the particular characteristics of each subgroup may detect the special health needs of the subgroup and lead to tailored interventions.
|
|
| 2. |
- Bushby, Katharine, et al.
(författare)
-
Ataluren treatment of patients with nonsense mutation dystrophinopathy.
- 2014
-
Ingår i: Muscle & nerve. - : Wiley. - 1097-4598 .- 0148-639X. ; 50:4, s. 477-87
-
Tidskriftsartikel (refereegranskat)abstract
- Dystrophinopathy is a rare, severe muscle disorder, and nonsense mutations are found in 13% of cases. Ataluren was developed to enable ribosomal readthrough of premature stop codons in nonsense mutation (nm) genetic disorders.
|
|
| 3. |
- Schmitz, Martin, et al.
(författare)
-
Rethinking Smart Objects : The International Workshop on Interacting with Smart Objects in Interactive Spaces
- 2022
-
Ingår i: ISS 2022. - New York, NY, USA : Association for Computing Machinery (ACM). ; , s. 64-67
-
Konferensbidrag (refereegranskat)abstract
- The increasing proliferation of smart objects in everyday life has changed how we interact with computers. Instead of concentrating computational capabilities and interaction into one device, everyday objects have naturally integrated parts of interactive features. Although this has led to many practical applications, the possibilities for explicit or implicit interaction with such objects are still limited in interaction spaces. We still often rely on smartphones as interactive hubs for controlling smart objects, hence not fulfilling the vision of truly smart objects. The workshop Rethinking Smart Objects invites practitioners and researchers from both academia and industry to discuss novel interaction paradigms and the integration and societal implications of using smart objects in interactive space. This workshop will include an action plan with leading questions, aiming to move the research field forward.
|
|
| 4. |
- Voit, Alexandra, et al.
(författare)
-
The attention Kitchen: Comparing modalities for smart home notifications in a cooking scenario
- 2021
-
Ingår i: ACM International Conference Proceeding Series. - New York, NY, USA : ACM. ; , s. 90-97
-
Konferensbidrag (refereegranskat)abstract
- A steadily increasing number of notifications, auditory, visual or ambient, competes for the user's attention. Frequent unsuitable notifications can lead to a breakdown in efficiency and increase error rates. This paper compares the effectiveness, disruptiveness, and user experience of three different notification modalities: On-Object, ambient On-Environment, and On-Smartphone notifications. In a user study with 24 participants, we evaluate the three notification modalities during a cooking task where users were frequently exposed to notifications. Our results show that ambient On-Environment notifications minimize the time in which users can resume their primary task. Ambient On-Environment notifications were also perceived as least disrupting compared to the other two notification modalities. We discuss the design requirements for non-disruptive notifications in smart home environments and conclude with future strategies for notifying users at different urgency levels.
|
|
